624 research outputs found
The association between distal findings and proximal colorectal neoplasia: a systematic review and meta-analysis
Objectives:
Whether screening participants with distal hyperplastic polyps (HPs) detected by flexible sigmoidoscopy (FS) should be followed by subsequent colonoscopy is controversial. We evaluated the association between distal HPs and proximal neoplasia (PN)/advanced proximal neoplasia (APN) in asymptomatic, average-risk patients.
Methods:
We searched Ovid Medline, EMBASE, and the Cochrane Library from inception to 30 June 2016 and included all screening studies that examined the relationship between different distal findings and PN/APN. Data were independently extracted by two reviewers with disagreements resolved by a third reviewer. We pooled absolute risks and odds ratios (ORs) with a random effects meta-analysis. Seven subgroup analyses were performed according to study characteristics. Heterogeneity was characterized with theI2 statistics.
Results:
We analyzed 28 studies (104,961 subjects). When compared with normal distal findings, distal HP was not associated with PN (OR=1.16, 95% confidence interval (CI)=0.89â1.51,P=0.14,I2=40%) or APN (OR=1.09, 95% CI=0.87â1.36,P=0.39,I2=5%), while subjects with distal non-advanced or advanced adenoma had higher odds of PN/APN. Higher odds of PN/APN were observed for more severe distal lesions. Weaker association between distal and proximal findings was noticed in studies with higher quality, larger sample size, population-based design, and more stringent endoscopy quality-control measures. The Eggerâs regression tests showed allP>0.05.
Conclusions:
Distal HP is not associated with PN/APN in asymptomatic screening population when compared with normal distal findings. Hence, the presence of distal HP alone detected by FS does not automatically indicate colonoscopy referral for all screening participants, as other risk factors of PN/APN should be considered
Mass measurements of neutron-deficient Y, Zr, and Nb isotopes and their impact on rp and Îœp nucleosynthesis processes
© 2018 The Authors. Published by Elsevier B.V. This manuscript is made available under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND 4.0). For further details please see: https://creativecommons.org/licenses/by-nc-nd/4.0/Using isochronous mass spectrometry at the experimental storage ring CSRe in Lanzhou, the masses of 82Zr and 84Nb were measured for the first time with an uncertainty of âŒ10 keV, and the masses of 79Y, 81Zr, and 83Nb were re-determined with a higher precision. The latter are significantly less bound than their literature values. Our new and accurate masses remove the irregularities of the mass surface in this region of the nuclear chart. Our results do not support the predicted island of pronounced low α separation energies for neutron-deficient Mo and Tc isotopes, making the formation of ZrâNb cycle in the rp-process unlikely. The new proton separation energy of 83Nb was determined to be 490(400) keV smaller than that in the Atomic Mass Evaluation 2012. This partly removes the overproduction of the p-nucleus 84Sr relative to the neutron-deficient molybdenum isotopes in the previous Îœp-process simulations.Peer reviewe
Dissecting the Genetic Basis of Resistance to Soybean Cyst Nematode Combining Linkage and Association Mapping
Partial Wave Analysis of
BES data on are presented. The
contribution peaks strongly near threshold. It is fitted with a
broad resonance with mass MeV, width MeV. A broad resonance peaking at 2020 MeV is also required
with width MeV. There is further evidence for a component
peaking at 2.55 GeV. The non- contribution is close to phase
space; it peaks at 2.6 GeV and is very different from .Comment: 15 pages, 6 figures, 1 table, Submitted to PL
Low-magnitude whole body vibration with resistive exercise as a countermeasure against cardiovascular deconditioning after 60 days of head-down bed rest
Whole body vibration with resistive exercise is a promising countermeasure against some weightlessness-induced dysfunctions. Our objective was to study whether the combination of low-magnitude whole body vibration with a resistive exercise can prevent the cardiovascular deconditioning induced by a nonstrict 60-day head-down bed rest (Earth Star International Bed Rest Experiment Project). Fourteen healthy men participated in this study. We recorded electrocardiograms and blood pressure waves by means of a noninvasive beat-by-beat measurement system (Cardiospace, integrated by Centre National d\u27Etudes Spatiales and Astronaut Center of China) during an orthostatic test (20 min of 75-degree head-up tilt test) before and immediately after bed rest. We estimated heart rate, blood pressure, cardiac output, stroke volume, total peripheral resistance, baroreflex sensitivity, and heart rate variability. Low-magnitude whole body vibration with resistive exercise prevented an increase of the sympathetic index (reflecting the sympathovagal balance of cardiac autonomic control) and limited the decrease of the spontaneous baroreflex sensitivity induced by 60 days of head-down bed rest. However, this countermeasure had very little effect on cardiac hemodynamics and did not improve the orthostatic tolerance. This combined countermeasure did not efficiently prevent orthostatic intolerance but prevents changes in the autonomic nervous system associated with cardiovascular deconditioning. The underlying mechanisms remain hypothetical but might involve cutaneous and muscular mechanoreceptors
The energy spectrum of all-particle cosmic rays around the knee region observed with the Tibet-III air-shower array
We have already reported the first result on the all-particle spectrum around
the knee region based on data from 2000 November to 2001 October observed by
the Tibet-III air-shower array. In this paper, we present an updated result
using data set collected in the period from 2000 November through 2004 October
in a wide range over 3 decades between eV and eV, in which
the position of the knee is clearly seen at around 4 PeV. The spectral index is
-2.68 0.02(stat.) below 1PeV, while it is -3.12 0.01(stat.) above 4
PeV in the case of QGSJET+HD model, and various systematic errors are under
study now.Comment: 12 pages, 7 figures, accepted by Advances in space researc
Moon Shadow by Cosmic Rays under the Influence of Geomagnetic Field and Search for Antiprotons at Multi-TeV Energies
We have observed the shadowing of galactic cosmic ray flux in the direction
of the moon, the so-called moon shadow, using the Tibet-III air shower array
operating at Yangbajing (4300 m a.s.l.) in Tibet since 1999. Almost all cosmic
rays are positively charged; for that reason, they are bent by the geomagnetic
field, thereby shifting the moon shadow westward. The cosmic rays will also
produce an additional shadow in the eastward direction of the moon if cosmic
rays contain negatively charged particles, such as antiprotons, with some
fraction. We selected 1.5 x10^{10} air shower events with energy beyond about 3
TeV from the dataset observed by the Tibet-III air shower array and detected
the moon shadow at level. The center of the moon was detected
in the direction away from the apparent center of the moon by 0.23 to
the west. Based on these data and a full Monte Carlo simulation, we searched
for the existence of the shadow produced by antiprotons at the multi-TeV energy
region. No evidence of the existence of antiprotons was found in this energy
region. We obtained the 90% confidence level upper limit of the flux ratio of
antiprotons to protons as 7% at multi-TeV energies.Comment: 13pages,4figures; Accepted for publication in Astroparticle Physic
The ARGO-YBJ Experiment Progresses and Future Extension
Gamma ray source detection above 30TeV is an encouraging approach for finding
galactic cosmic ray origins. All sky survey for gamma ray sources using wide
field of view detector is essential for population accumulation for various
types of sources above 100GeV. To target the goals, the ARGO-YBJ experiment has
been established. Significant progresses have been made in the experiment. A
large air shower detector array in an area of 1km2 is proposed to boost the
sensitivity. Hybrid detection with multi-techniques will allow a good
discrimination between different types of primary particles, including photons
and protons, thus enable an energy spectrum measurement for individual specie.
Fluorescence light detector array will extend the spectrum measurement above
100PeV where the second knee is located. An energy scale determined by balloon
experiments at 10TeV will be propagated to ultra high energy cosmic ray
experiments
Charm multiplicity and the branching ratios of inclusive charmless b quark decays in the general two-Higgs-doublet models
In the framework of general two-Higgs-doublet models, we calculate the
branching ratios of various inclusive charmless b decays by using the low
energy effective Hamiltonian including next-to-leading order QCD corrections,
and examine the current status and the new physics effects on the determination
of the charm multiplicity and semileptonic branching ratio .
Within the considered parameter space, the enhancement to the ratio due to the charged-Higgs penguins can be as large as a factor of 8 (3) in
the model III (II), while the ratio can be increased from
the standard model prediction of 2.49% to 4.91% (2.99%) in the model III (II).
Consequently, the value of and can be decreased simultaneously
in the model III. The central value of will be lowered slightly by
about 0.003, but the ratio can be reduced significantly from the
theoretical prediction of in the SM to , for GeV, respectively. We find that
the predicted and the measured now agree within roughly one
standard deviation after taking into account the effects of gluonic charged
Higgs penguins in the model III with a relatively light charged Higgs boson.Comment: 25 pages, Latex file, axodraw.sty, 6 figures. Final version to be
published in Phys.Rev.
High Altitude test of RPCs for the ARGO-YBJ experiment
A 50 m**2 RPC carpet was operated at the YangBaJing Cosmic Ray Laboratory
(Tibet) located 4300 m a.s.l. The performance of RPCs in detecting Extensive
Air Showers was studied. Efficiency and time resolution measurements at the
pressure and temperature conditions typical of high mountain laboratories, are
reported.Comment: 16 pages, 10 figures, submitted to Nucl. Instr. Met
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