CRANIAL AND POST-CRANIAL TRAUMATIC INJURY PATTERNS IN VAN CASTLE MOUND MEDIEVAL POPULATION

The excavations conducted at Van Castle Mound, East Anatolia, between 1987 and 2010 uncovered a total of 328 human skeletons dating back to the Medieval period. Thirty trauma cases were identified within the collection, constituting 9.14% of the entire population. Typology and distribution of the trauma among different sexes indicated that depression fractures, oblique fractures, comminuted fractures, and head deformation were more frequently observed in male skeletons, while a post-fractural infection appeared only in a female skeleton. Trauma cases were more common on post-cranial bones. In addition, a trepanned cranial specimen belonging to a mature individual is identified in which grooving technique was performed. Most of the observed trauma cases were related to heavy labor, unsafe working conditions, and challenges of everyday agrarian life. Previous paleopathological studies from the Medieval Van Castle Mound also indicates an insufficient nutritation and high physical stress.Peer reviewe

Ovarian cancer molecular pathology.

Peer reviewe

Incidental CT Findings of Patients Who Admitted to ER Following a Traffic Accident

SUMMARYObjectiveThe aim of this study was to investigate and analyze incidental CT findings of traffic injury patients discharged from the ER, and to determine overall notification rates.MethodsAll traffic injury-related patient records between 01.06.2013–01.03.2013 were obtained from Derince Training and Research Hospital Emergency Service using patient files and the hospital database. Brain, thorax and/or abdominal CT images of 340 patients aged between 0 to 84 years were included in the study. ER observation forms were investigated for the patients who had incidental findings on CT scanning and overall notification rates were recorded.ResultsMean age of the 363 cases was 31.2 (SD 17.9, min 0, max 84) and 35.5% of patients were female (n=129) and 64.5% were male (n=234). A total of 537 CT scans were performed on 363 patients. 147, 319 and 71 CT scans were performed on the thorax, brain and abdominal, respectively. 27.3% (n=99) of scan results showed the presence of a coincidental pathology. The most common disease on scans were bone lesions (8%, n=29), followed by sinus abnormalities (7.7%, n=28). Incidental findings ratio in patients aged over 60 was 60.8%, while under 60 was 24.8%. It was found that seven patients (7.1%) were informed about the imaging results.ConclusionMost of the incidental findings were found to be benign; however, 16.5% of them were considered to require in-depth investigation. Further investigations are needed to understand the clinical relevance of these findings and their effects on patients

Brentuximab vedotin related bilateral Purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection

We describe a 36-year-old woman with a relapsing Hodgkin’s lymphoma who developed a severe bilateral sudden visual loss almost three weeks after the initiation of brentuximab therapy. Ancillary fundus tests yielded bilateral severe retinal arteriolar occlusion 360° and serous macular retinal detachment. No visual improvement could be achieved despite the pulse corticosteroid therapy and a single bilateral intravitreal aflibercept administration cessation of the brentuximab therapy. Unfortunately, she succumbed to respiratory failure almost six weeks after the diagnosis of Purtscher-like retinopathy

Esophageal muscle cell interaction with biopolymers

Background: The in vitro interactions of esophageal smooth muscle cells (SMCs) with synthetic absorbable polymers were tested and artificial muscle tissues harvested from subcutaneous implantation were examined

The Analysis of Escherichia Coli Resistance in Urine Culture and in Antibiograms as Requested by Emergency Service

SUMMARY: Objectives: The aim of this study was to determine the antibiotic resistance of infectious and non-infectious E. coli species in order to increase the success of empirical antibiotic treatment in urinary system infections. Methods: The antibiotic susceptibility of 464 E. coli strains that were isolated from urine samples of patients who visited Derince Training and Research Hospital Emergency Department between January 1 and December 31, 2012 were retrospectively evaluated from records. The antibiogram results were classified as susceptible, moderately susceptible or resistant. Moderately susceptible strains were assumed to be resistant. Results: Bacterial proliferation was seen in 563 (28.1%) of the 1998 urine cultures tested. One hundred and twelve cultures could not be evaluated due to contamination, and there was no proliferation in 1323 cultures. E. coli strains were isolated in 464 (82.4%) of the cultures in which proliferation was seen. Three hundred and sixty seven (79%) of the patients were female, 97 (21%) were male, and the mean age of all of the patients was 41.1±24.1 years (min: 1, max: 90). The antibiograms of the E. coli strains revealed that meropenem had the lowest resistance (0%), while ampicillin-sulbactam had the highest resistance (36.8%). Conclusions: In this study, we investigated the antibiotic resistance of E. coli strains isolated from urine cultures in our region. Future studies, perhaps similar to this one, can be performed in the future to increase the success of treatments. ÖZET: Amaç: Bu çalışmada üriner sistem enfeksiyonlarında ampirik antibiyotik tedavi başarısını artırmak için enfeksiyon etkeni olan veya olmayan E.coli suşlarının çeşitli antibiyotik türlerine direnci araştırıldı. Gereç ve Yöntem: 1 Ocak-31 Aralık 2012 tarihleri arasında Derince Eğitim ve Araştırma Hastanesi acil servisine başvuran hastaların mikrobiyoloji laboratuvarına gönderilmiş idrar örneklerinden izole edilen 464 E.coli suşunun antibiyotik duyarlılıkları bilgisayar kayıtları üzerinden retrospektif olarak değerlendirildi. Antibiyogram sonuçları duyarlı, orta duyarlı ve dirençli olarak sınıflandırıldı. Orta duyarlı suşlar dirençli kabul edildi. Bulgular: 1998 idrar kültüründen 563'ünde (%28.1) üreme oldu. Kültürlerin 112'si kontaminasyon nedeniyle değerlendirilemedi, 1323 kültürde ise üreme olmadı. Üreme olan kültürlerden 464'ünde (%82.4) E.coli suşları izole edildi. Hastaların 367'si (%79) kadın 97'si (%21) erkek, tüm hastaların yaş ortalaması 41.1±24.1 (min: 1, maks: 90) idi. E.coli suşlarına karşı antibiyogramlar incelendiğinde, direncin en düşük görüldüğü antibiyotik meropenem (%0), en yüksek görüldüğü antibiyotik ise ampisilinsulbaktam olarak saptandı (%36.8). Sonuç: Bölgemizde idrar kültürlerinden izole edilen E.coli suşlarına karşı antibiyotik dirençlerini incelediğimiz çalışmamızın benzerlerinin ilerleyen dönemde yapılmasının tedavi başarısına yardımcı olacağını düşünmekteyiz. Key words: Culture, E. coli, emergency, urine, Anahtar sözcükler: Kültür, E.coli, acil, idra