207 research outputs found
Evaluasi Penggunaan Augmented Reality sebagai Media Ajar Pengenalan Benda Sekitar pada Kelompok Bermain
Penelitian ini telah melakukan analisis penggunaan Augmented Reality (AR) untuk pembelajaran pada kelompok bermain dengan topik pengenalan benda secara 3D. Metode dalam penelitian ini adalah waterfall diawali dengan observasi, rancang bangun aplikasi dan pengujian aplikasi. Observasi dilakukan pada 2 tempat yaitu pada kelompok bermain Ayah Bunda dan Pos PAUD di Kecamatan Colomadu. Aplikasi dikembangkan menggunakan openspace. Pengujian aplikasi dilakukan secara black box, sedangkan analisis pengujian aplikasi terhadap daya tarik pengunjung dilakukan melalui angket kuisioner dengan skala butir pertanyaan menggunakan skala Likert dalam 6 skala nilai. Responden yang mengisi angket kuisioner sejumlah 33 terdiri dari pengasuh dan wali murid. Tanggapan terhadap aplikasi diwujudkan dalam 5 aspek bernilai setuju-sangat setuju yaitu aspek ketertarikan terhadap aplikasi 93%, aspek kemudahan mendapatkan informasi 97%, aspek kemudahan navigasi 100%, aspek interaktifitas aplikasi 94%, dan aspek inovasi aplikasi 97%
Polynomial Structure of the (Open) Topological String Partition Function
In this paper we show that the polynomial structure of the topological string
partition function found by Yamaguchi and Yau for the quintic holds for an
arbitrary Calabi-Yau manifold with any number of moduli. Furthermore, we
generalize these results to the open topological string partition function as
discussed recently by Walcher and reproduce his results for the real quintic.Comment: 15 page
Dessins d'enfants in N=2 generalised quiver theories
We study Grothendieck’s dessins d’enfants in the context of the N=2 supersymmetric gauge theories in (3 + 1) dimensions with product SU (2) gauge groups which have recently been considered by Gaiotto et al.. We identify the precise context in which dessins arise in these theories: they are the so-called ribbon graphs of such theories at certain isolated points in the moduli space. With this point in mind, we highlight connections to other work on trivalent dessins, gauge theories, and the modular group
The holomorphic anomaly for open string moduli
We complete the holomorphic anomaly equations for topological strings with
their dependence on open moduli. We obtain the complete system by standard path
integral arguments generalizing the analysis of BCOV (Commun. Math. Phys. 165
(1994) 311) to strings with boundaries. We study both the anti-holomorphic
dependence on open moduli and on closed moduli in presence of Wilson lines. By
providing the compactification a' la Deligne-Mumford of the moduli space of
Riemann surfaces with boundaries, we show that the open holomorphic anomaly
equations are structured on the (real codimension one) boundary components of
this space.Comment: 1+14 pages, 6 figures! v2: ref. added v3: section 4 expanded, 1+17
pages, 11 figures!!, to be publ. in JHE
Structure and dynamics of ring polymers: entanglement effects because of solution density and ring topology
The effects of entanglement in solutions and melts of unknotted ring polymers
have been addressed by several theoretical and numerical studies. The system
properties have been typically profiled as a function of ring contour length at
fixed solution density. Here, we use a different approach to investigate
numerically the equilibrium and kinetic properties of solutions of model ring
polymers. Specifically, the ring contour length is maintained fixed, while the
interplay of inter- and intra-chain entanglement is modulated by varying both
solution density (from infinite dilution up to \approx 40 % volume occupancy)
and ring topology (by considering unknotted and trefoil-knotted chains). The
equilibrium metric properties of rings with either topology are found to be
only weakly affected by the increase of solution density. Even at the highest
density, the average ring size, shape anisotropy and length of the knotted
region differ at most by 40% from those of isolated rings. Conversely, kinetics
are strongly affected by the degree of inter-chain entanglement: for both
unknots and trefoils the characteristic times of ring size relaxation,
reorientation and diffusion change by one order of magnitude across the
considered range of concentrations. Yet, significant topology-dependent
differences in kinetics are observed only for very dilute solutions (much below
the ring overlap threshold). For knotted rings, the slowest kinetic process is
found to correspond to the diffusion of the knotted region along the ring
backbone.Comment: 17 pages, 11 figure
Geometric Mixing, Peristalsis, and the Geometric Phase of the Stomach
Mixing fluid in a container at low Reynolds number - in an inertialess
environment - is not a trivial task. Reciprocating motions merely lead to
cycles of mixing and unmixing, so continuous rotation, as used in many
technological applications, would appear to be necessary. However, there is
another solution: movement of the walls in a cyclical fashion to introduce a
geometric phase. We show using journal-bearing flow as a model that such
geometric mixing is a general tool for using deformable boundaries that return
to the same position to mix fluid at low Reynolds number. We then simulate a
biological example: we show that mixing in the stomach functions because of the
"belly phase": peristaltic movement of the walls in a cyclical fashion
introduces a geometric phase that avoids unmixing.Comment: Revised, published versio
Holomorphicity and Modularity in Seiberg-Witten Theories with Matter
We calculate the gravitational corrections to the effective action of N=2
SU(2) Seiberg-Witten theory with matter using modularity, the holomorphic
anomaly equation and expected behavior at the boundaries of the moduli space.
As in pure gauge theory we show that the gap condition at the dyon
singularities completely fixes the gravitational corrections. We discuss the
behavior of the gravitational corrections at the conformal points. We compare
our results with the recursive solution of the loop equation in the matrix
model approach, which provides in addition open amplitudes.Comment: 53 pages, no figure
AFe2As2 (A = Ca, Sr, Ba, Eu) and SrFe_(2-x)TM_(x)As2 (TM = Mn, Co, Ni): crystal structure, charge doping, magnetism and superconductivity
The electronic structure and physical properties of the pnictide compound
families OFeAs ( = La, Ce, Pr, Nd, Sm), FeAs ( = Ca,
Sr, Ba, Eu), LiFeAs and FeSe are quite similar. Here, we focus on the members
of the FeAs family whose sample composition, quality and single
crystal growth are better controllable compared to the other systems. Using
first principles band structure calculations we focus on understanding the
relationship between the crystal structure, charge doping and magnetism in
FeAs systems. We will elaborate on the tetragonal to
orthorhombic structural distortion along with the associated magnetic order and
anisotropy, influence of doping on the site as well as on the Fe site, and
the changes in the electronic structure as a function of pressure.
Experimentally, we investigate the substitution of Fe in
SrFeAs by other 3 transition metals, = Mn, Co, Ni.
In contrast to a partial substitution of Fe by Co or Ni (electron doping) a
corresponding Mn partial substitution does not lead to the supression of the
antiferromagnetic order or the appearance of superconductivity. Most calculated
properties agree well with the measured properties, but several of them are
sensitive to the As position. For a microscopic understanding of the
electronic structure of this new family of superconductors this structural
feature related to the Fe-As interplay is crucial, but its correct ab initio
treatment still remains an open question.Comment: 27 pages, single colum
Energy-band engineering for improved charge retention in fully self-aligned double floating-gate single-electron memories
We present a new fully self-aligned single-electron memory with a single pair
of nano floating gates, made of different materials (Si and Ge). The energy
barrier that prevents stored charge leakage is induced not only by quantum
effects but also by the conduction-band offset that arises between Ge and Si.
The dimension and position of each floating gate are well defined and
controlled. The devices exhibit a long retention time and single-electron
injection at room temperature
Multiple molecular mechanisms form a positive feedback loop driving amyloid β42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons
Emerging evidence supports an important role for the ROS-sensitive TRPM2 channel in mediating age-related cognitive impairment in Alzheimer’s disease (AD), particularly neurotoxicity resulting from generation of excessive neurotoxic Aβ peptides. Here we examined the elusive mechanisms by which Aβ₄₂ activates the TRPM2 channel to induce neurotoxicity in mouse hippocampal neurons. Aβ₄₂-induced neurotoxicity was ablated by genetic knockout (TRPM2-KO) and attenuated by inhibition of the TRPM2 channel activity or activation through PARP-1. Aβ₄₂-induced neurotoxicity was also inhibited by treatment with TPEN used as a Zn²⁺-specific chelator. Cell imaging revealed that Aβ₄₂-induced lysosomal dysfunction, cytosolic Zn²⁺ increase, mitochondrial Zn²⁺ accumulation, loss of mitochondrial function, and mitochondrial generation of ROS. These effects were suppressed by TRPM2-KO, inhibition of TRPM2 or PARP-1, or treatment with TPEN. Bafilomycin-induced lysosomal dysfunction also resulted in TRPM2-dependent cytosolic Zn²⁺ increase, mitochondrial Zn²⁺ accumulation, and mitochondrial generation of ROS, supporting that lysosomal dysfunction and accompanying Zn²⁺ release trigger mitochondrial Zn²⁺ accumulation and generation of ROS. Aβ₄₂-induced effects on lysosomal and mitochondrial functions besides neurotoxicity were also suppressed by inhibition of PKC and NOX. Furthermore, Aβ₄₂-induced neurotoxicity was prevented by inhibition of MEK/ERK. Therefore, our study reveals multiple molecular mechanisms, including PKC/NOX-mediated generation of ROS, activation of MEK/ERK and PARP-1, lysosomal dysfunction and Zn²⁺ release, mitochondrial Zn²⁺ accumulation, loss of mitochondrial function, and mitochondrial generation of ROS, are critically engaged in forming a positive feedback loop that drives Aβ₄₂-induced activation of the TRPM2 channel and neurotoxicity in hippocampal neurons. These findings shed novel and mechanistic insights into AD pathogenesis
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