On arithmetic detection of grey pulses with application to Hawking radiation

Micron-sized black holes do not necessarily have a constant horizon temperature distribution. The black hole remote-sensing problem means to find out the `surface' temperature distribution of a small black hole from the spectral measurement of its (Hawking) grey pulse. This problem has been previously considered by Rosu, who used Chen's modified Moebius inverse transform. Here, we hint on a Ramanujan generalization of Chen's modified Moebius inverse transform that may be considered as a special wavelet processing of the remote-sensed grey signal coming from a black hole or any other distant grey sourceComment: 5 pages, published versio

Structure-Induced Reversible Anionic Redox Activity in Na Layered Oxide Cathode

Anionic redox reaction (ARR) in lithium- and sodium-ion batteries is under hot discussion, mainly regarding how oxygen anion participates and to what extent oxygen can be reversibly oxidized and reduced. Here, a P3-type Na0.6[Li0.2Mn0.8]O2 with reversible capacity from pure ARR was studied. The interlayer O-O distance (peroxo-like O-O dimer, 2.506(3) Å), associated with oxidization of oxygen anions, was directly detected by using a neutron total scattering technique. Different from Li2RuO3 or Li2IrO3 with strong metal-oxygen (M-O) bonding, for P3-type Na0.6[Li0.2Mn0.8]O2 with relatively weak Mn-O covalent bonding, crystal structure factors might play an even more important role in stabilizing the oxidized species, as both Li and Mn ions are immobile in the structure and thus may inhibit the irreversible transformation of the oxidized species to O2 gas. Utilization of anionic redox reaction (ARR) on oxygen has been considered as an effective way to promote the charge-discharge capacity of the layered oxide cathodes for lithium- or sodium-ion batteries. The detailed mechanism of ARR, in particular how crystal structure affects and coordinates with the ARR, is not yet well understood. In the present work, a combination of X-ray and neutron total scattering measurements has been performed to study the structure of the prototype P3-type layered Na0.6[Li0.2Mn0.8]O2 with pure ARR. Unique structural characteristics, rather than prevailing knowledge of covalency of metal-oxygen, enable the stabilization of the crystal structure of Na0.6[Li0.2Mn0.8]O2 along with the ARR. This work suggests that reversible ARR can be manipulated by proper structure designs, thus to achieve high lithium or sodium storage in layered oxide cathodes. For P3-type Na0.6[Li0.2Mn0.8]O2 with relatively weak Mn-O covalent bonding, crystal structure factors play an important role in stabilizing the oxidized species, inhibiting the irreversible transformation of the oxidized species to O2 gas. The finding is important for better design of layered oxide positive materials with higher reversible capacity via the introduction of a reversible anionic redox reaction

The Neural Basis for Spatial Relations

Studies in semantics traditionally focus on knowledge of objects. By contrast, less is known about how objects relate to each other. In an fMRI study, we tested the hypothesis that the neural processing of categorical spatial relations between objects is distinct from the processing of the identity of objects. Attending to the categorical spatial relations compared with attending to the identity of objects resulted in greater activity in superior and inferior parietal cortices (especially on the left) and posterior middle frontal cortices bilaterally. In an accompanying lesion study, we tested the hypothesis that comparable areas would be necessary to represent categorical spatial relations and that the hemispheres differ in their biases to process categorical or coordinate spatial relations. Voxelbased lesion symptom mapping results were consistent with the fMRI observations. Damage to a network comprising left inferior frontal, supramarginal, and angular gyri resulted in behavioral impairment on categorical spatial judgments. Homologous right brain damage also produced such deficits, albeit less severely. The reverse pattern was observed for coordinate spatial processing. Right brain damage to the middle temporal gyrus produced more severe deficits than left hemisphere damage. Additional analyses suggested that some areas process both kinds of spatial relations conjointly and others distinctly. The left angular and inferior frontal gyrus processes coordinate spatial information over and above the categorical processing. The anterior superior temporal gyrus appears to process categorical spatial information uniquely. No areas within the right hemisphere processed categorical spatial information uniquely. Taken together, these findings suggest that the functional neuroanatomy of categorical and coordinate processing is more nuanced than implied by a simple hemispheric dichotomy

Extragalactic Point Source Search in Five-year WMAP 41, 61 and 94 GHz Maps

We present the results of an extragalactic point source search using the five-year WMAP 41, 61 and 94 GHz (Q-, V- and W-band) temperature maps. This work is an extension of our point source search in the WMAP maps applying a CMB-free technique. An internal linear combination (ILC) map has been formed from the three-band maps, with the weights chosen to remove the CMB anisotropy signal as well as to favor a selection of flat-spectrum sources. We find 381 sources at the > 5 sigma level outside the WMAP point source detection mask in the ILC map, among which 89 are "new" (i.e., not present in the WMAP catalog). Source fluxes have been calculated and corrected for the Eddington bias. We have solidly identified 367 (96.3%) of our sources. The 1 sigma positional uncertainty is estimated to be 2'. The 14 unidentified sources could be either extended radio structure or obscured by Galactic emission. We have also applied the same detection process on simulated maps and found 364+/-21 detections on average. The recovered source distribution N(>S) agrees well with the simulation input, which proves the reliability of this method.Comment: 28 pages, 9 figures, 2 tables, accepted by Ap

Effect of patient sex on triage for ischaemic heart disease and treatment onset times: a retrospective analysis of Australian emergency department data

AbstractTime between emergency department (ED) presentation and treatment onset is an important, but little-researched phase within the revascularization process for ischaemic heart disease (IHD).ObjectiveTo determine if sex influences triage score allocation and treatment onset for patients with IHD in the ED.MethodsRetrospective data for patients 18–85years presenting to EDs from 2005 to 2010 for acute myocardial infarction (AMI), unstable and stable angina, and chest pain were analysed collectively and separately for AMI.ResultsProportionately more men (61% of males) were triaged correctly for AMI than women (51.4% of females; P<0.001). Across all triage categories, average treatment time was faster for men than women with AMI (P<0.001). When incorrectly triaged for AMI, treatment time for men was faster than for women (P=0.04). When correctly triaged for AMI, there was no difference in mean treatment time between men and women (P=0.538).ConclusionsSubstantial undertriage of AMI occurred for both sexes, but was worse in women. Incorrect triage led to prolonged treatment times for AMI, with women’s treatment delays longer than men’s. When triaged correctly, both sexes were treated early for AMI, emphasising the need for all patients to be accurately triaged for this time-sensitive disease

Influence of opioids on immune function in patients with cancer pain: from bench to bedside

In patients with cancer, opioids are principally used for the management of acute surgical and chronic cancer-related pain. However, opioids have many non-analgesic effects, including direct and indirect effects on cancer cells and on anti-tumour immunity (NK cells, macrophages and T-cells). Direct effects on immune cells are manifested via opioid and non-opioid toll-like receptors, whereas indirect effects are manifested via the sympathetic nervous system and hypothalamic–pituitary–adrenal axis. Opioids can also decrease/alter immune cell infiltration into the tumour micro-environment. Animal models have shown that this is not a class effect, in that morphine and fentanyl suppress NK cell cytotoxicity; buprenorphine does not affect NK cell cytotoxicity, whereas tramadol increases NK cell cytotoxicity, reducing metastasis. In healthy individuals, morphine suppresses and fentanyl enhances NK cell cytotoxicity. In patients undergoing surgery, fentanyl decreased and tramadol increased NK cell cytotoxicity; clinical outcomes were not determined. Meta-analyses of opioid-sparing surgical studies report an association between improved recurrence-free and/or overall survival with regional/neuraxial anaesthesia compared with systemic opioids. In patients receiving opioids for non-surgical cancer-related pain, morphine has variable effects on immunity; clinical outcomes were not assessed. Although there is a potential association between systemic opioid administration and shorter survival in cancer patients with a prognosis of months to years, studies have not been designed to primarily assess survival, as a consequence of which causality cannot be apportioned. Pain is immunosuppressive, so analgesia is important. Opioids for cancer-related pain will continue to be recommended until definitive data on the effects of opioids on clinical outcomes in specific patient groups becomes available

The Luminosity Function Evolution of Soft X--ray selected AGN in the RIXOS survey

A sample of 198 soft X--ray selected active galactic nuclei (AGN) from the ROSAT International X--ray Optical Survey (RIXOS), is used to investigate the X--ray luminosity function and its evolution. RIXOS, with a flux limit of 3E-14 erg s-1 cm-2 (0.5 to 2.0 keV), samples a broad range in redshift over 20 deg^2 of sky, and is almost completely identified; it is used in combination with the Einstein Extended Medium Sensitivity Survey (EMSS), to give a total sample of over 600 AGN. We find the evolution of AGN with redshift to be consistent with pure luminosity evolution (PLE) models in which the rate of evolution slows markedly or stops at high redshifts z>1.8. We find that this result is not affected by the inclusion, or exclusion, of narrow emission line galaxies at low redshift in the RIXOS and EMSS samples, and is insensitive to uncertainties in the conversion between flux values measured with ROSAT and Einstein. We confirm, using a model independent Ve/Va test, that our survey is consistent with no evolution at high redshifts.Comment: 10 pages, LaTeX file, PS figures and mn.sty. Accepted in MNRA

X-ray spectra of XMM-Newton serendipitous medium flux sources

We report on the results of a detailed analysis of the X-ray spectral properties of a large sample of sources detected serendipitously with the XMM-Newton observatory in 25 selected fields. The survey covers a total solid angle of ~3.5 deg2 and contains 1137 sources with ~10E-15 < S0.5-10 < 10E-12 erg cm-2 s-1. We find evidence for hardening of the average X-ray spectra of the sources towards fainter fluxes. We interpret this as indicating a higher degree of photoelectric absorption amongst the fainter population. Absorption is detected at 95% confidence in 20% of the sources, but it could certainly be present in many other sources below our detection capabilities. For Broad Line AGNs (BLAGNs), we detect absorption in ~10% of the sources with column densities in the range 10E21 - 10E22 cm-2. The fraction of absorbed Narrow Emission Line galaxies (NELGs, most with intrinsic X-ray luminosities >10E43 erg s-1, and therefore classified as type 2 AGNs) is significantly higher (40%), with a hint of moderately higher columns. We do not find evidence for a redshift evolution of the underlying power law index of BLAGNs, which stays roughly constant at Gamma ~1.9, with intrinsic dispersion of 0.4. A small fraction (~7%) of BLAGNs and NELGs require the presence of a soft excess, that we model as a black body with temperature ranging from 0.1 to 0.3 keV. Comparing our results on absorption to popular X-ray background synthesis models, we find absorption in only ~40% of the sources expected. This is due to a deficiency of heavily absorbed sources (with NH ~10E22 - 10E24 cm-2) in our sample in comparison with the models. We therefore conclude that the synthesis models require some revision in their specific parameters.Comment: 20 pages, 30 Postscript figures, A&A in pres

Special biconformal changes of K\"ahler surface metrics

The term "special biconformal change" refers, basically, to the situation where a given nontrivial real-holomorphic vector field on a complex manifold is a gradient relative to two K\"ahler metrics, and, simultaneously, an eigenvector of one of the metrics treated, with the aid of the other, as an endomorphism of the tangent bundle. A special biconformal change is called nontrivial if the two metrics are not each other's constant multiples. For instance, according to a 1995 result of LeBrun, a nontrivial special biconformal change exists for the conformally-Einstein K\"ahler metric on the two-point blow-up of the complex projective plane, recently discovered by Chen, LeBrun and Weber; the real-holomorphic vector field involved is the gradient of its scalar curvature. The present paper establishes the existence of nontrivial special biconformal changes for some canonical metrics on Del Pezzo surfaces, viz. K\"ahler-Einstein metrics (when a nontrivial holomorphic vector field exists), non-Einstein K\"ahler-Ricci solitons, and K\"ahler metrics admitting nonconstant Killing potentials with geodesic gradients.Comment: 16 page

Simulated SKA maps from Galactic 3D-emission models

(Abridged) We present maps for various Galactic longitudes and latitudes at 1.4 GHz, which is the frequency where deep SKA surveys are proposed. The maps are about 1.5 deg in size and have an angular resolution of about 1.6 arcsec. We analyse the maps in terms of their probability density functions (PDFs) and structure functions. Total intensity emission is more smooth in the plane than at high latitudes due to the different contributions from the regular and random magnetic field. The high latitude fields show more extended polarized emission and RM structures than those in the plane, where patchy emission structures on very small scales dominate. The RM PDFs in the plane are close to Gaussians, but clearly deviate from that at high latitudes. The RM structure functions show smaller amplitudes and steeper slopes towards high latitudes. These results emerge from the fact that much more turbulent cells are passed through by the line-of-sights in the plane. Although the simulated random magnetic field components distribute in 3D, the magnetic field spectrum extracted from the structure functions of RMs conforms to 2D in the plane and approaches 3D at high latitudes. This is partly related to the outer scale of the turbulent magnetic field, but mainly to the different lengths of the line-of-sights.Comment: 19 pages, 15 figures, accepted for publication in Astronomy and Astrophysics. The sizes of figures have been significantly reduced. For the version with full resolution, see ftp://ftp.mpifr-bonn.mpg.de/outgoing/p098wre/sun-reich.pd