Evaluating Research Survey Websites in Kinesiology: A Case Study Using An Accessibility Rating Form

Advancing equity in the research and educational practice of kinesiology requires intentional efforts to ensure access divides do not widen nor persist (Ross et al., in press, JOPERD). PURPOSE: Given knowledge of suitability assessment of materials (SAM) principles supports the equitable design of lay print and online material, we evaluated the extent they would also support developing a research survey website consistent with accessibility guidelines for digital technology. METHODS: The study website was adapted from the Canvas learning management system. A cross-sectional formative assessment was performed. Using their knowledge of SAM principles (eg, clear layout, text ≤ 8th grade reading level), the second and third author (JDT, RFH) constructed the website webpages (eg, site welcome page, online questionnaire; Jun.-Jul. 2022). The first author (YSW), using guidelines from two reputable sources (ie, a Canvas tutorial and W3C website), developed a 14-item accessibility rating form to critically appraise the website’s 10 webpages (ie, 1 = Not Accessible, 2 = Somewhat Accessible, 3 = Accessible; Wallace et al., 2010, JPAH). Authors 1-4 then performed a formative assessment of the adapted Canvas websites’ accessibility independently (Jul.-Aug. 2022). Form reliability was assessed using the intraclass correlation coefficient and its interpretive cut-points for average absolute-rater agreement (Cicchetti, 1994, Psych Assess; Landers, 2015, Winnower). RESULTS: Average rater agreement was excellent per webpage (M = .91, LL = .82, UL = .94). Mean webpage score ranged between 2.55 (±0.78) to 2.77 (±0.58). Informational pages (eg, welcome page) had greater accessibility than interactive pages (eg, forms). Five discrepant items were systematic, resulting in redundant rater differences (eg, keyboard navigation was hard to notice). All discrepancies were resolved with 100% consensus. CONCLUSION: The findings of the present study suggest knowledge of SAM principles ensures developers can design lay friendly and accessible research survey websites. They further suggest rating forms inclusive of digital accessibility guidelines should be used as a supplement to further meet accessibility and equity goals. We will share our form, then discuss our results using the universal design for learning framework

Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.

Advances in the surgical management of the axilla in patients treated with neoadjuvant chemotherapy, especially those with node positive disease at diagnosis, have led to changes in practice and more judicious use of axillary lymph node dissection that may minimize morbidity from surgery. However, there is still significant confusion about how to optimally manage the axilla, resulting in variation among practices. From the viewpoint of drug development, assessment of response to neoadjuvant chemotherapy remains paramount and appropriate assessment of residual disease-the primary endpoint of many drug therapy trials in the neoadjuvant setting-is critical. Therefore decreasing the variability, especially in a multicenter clinical trial setting, and establishing a minimum standard to ensure consistency in clinical trial data, without mandating axillary lymph node dissection, for all patients is necessary. The key elements which include proper staging and identification of nodal involvement at diagnosis, and appropriately targeted management of the axilla at the time of surgical resection are presented. The following protocols have been adopted as standard procedure by the I-SPY2 trial for management of axilla in patients with node positive disease, and present a framework for prospective clinical trials and practice

Erratum: Author Correction: Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.

[This corrects the article DOI: 10.1038/s41523-018-0074-6.]

A New Model of Delirium Care in the Acute Geriatric Setting: Geriatric Monitoring Unit

<p>Abstract</p> <p>Background</p> <p>Delirium is a common and serious condition, which affects many of our older hospitalised patients. It is an indicator of severe underlying illness and requires early diagnosis and prompt treatment, associated with poor survival, functional outcomes with increased risk of institutionalisation following the delirium episode in the acute care setting. We describe a new model of delirium care in the acute care setting, titled Geriatric Monitoring Unit (GMU) where the important concepts of delirium prevention and management are integrated. We hypothesize that patients with delirium admitted to the GMU would have better clinical outcomes with less need for physical and psychotropic restraints compared to usual care.</p> <p>Methods/Design</p> <p>GMU models after the Delirium Room with adoption of core interventions from Hospital Elder Life Program and use of evening bright light therapy to consolidate circadian rhythm and improve sleep in the elderly patients. The novelty of this approach lies in the amalgamation of these interventions in a multi-faceted approach in acute delirium management. GMU development thus consists of key considerations for room design and resource planning, program specific interventions and daily core interventions. Assessments undertaken include baseline demographics, comorbidity scoring, duration and severity of delirium, cognitive, functional measures at baseline, 6 months and 12 months later. Additionally we also analysed the pre and post-GMU implementation knowledge and attitude on delirium care among staff members in the geriatric wards (nurses, doctors) and undertook satisfaction surveys for caregivers of patients treated in GMU.</p> <p>Discussion</p> <p>This study protocol describes the conceptualization and implementation of a specialized unit for delirium management. We hypothesize that such a model of care will not only result in better clinical outcomes for the elderly patient with delirium compared to usual geriatric care, but also improved staff knowledge and satisfaction. The model may then be transposed across various locations and disciplines in the acute hospital where delirious patients could be sited.</p> <p>Trial Registration</p> <p>Current Controlled Trials <a href="http://www.controlled-trials.com/ISRCTN52323811">ISRCTN52323811</a></p

Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia

The leukemogenic effects of Myc drive recurrent trisomy in a mouse model of acute myeloid leukemia

Molecular Characterization of Branchial aquaporin 1aa and Effects of Seawater Acclimation, Emersion or Ammonia Exposure on Its mRNA Expression in the Gills, Gut, Kidney and Skin of the Freshwater Climbing Perch, Anabas testudineus

10.1371/journal.pone.0061163PLoS ONE84