Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies

The life sciences are currently being transformed by an unprecedented wave of developments in molecular analysis, which include important advances in instrumental analysis as well as biocomputing. In light of the central role played by metabolism in nutrition, metabolomics is rapidly being established as a key analytical tool in human nutritional studies. Consequently, an increasing number of nutritionists integrate metabolomics into their study designs. Within this dynamic landscape, the potential of nutritional metabolomics (nutrimetabolomics) to be translated into a science, which can impact on health policies, still needs to be realized. A key element to reach this goal is the ability of the research community to join, to collectively make the best use of the potential offered by nutritional metabolomics. This article, therefore, provides a methodological description of nutritional metabolomics that reflects on the state‐of‐the‐art techniques used in the laboratories of the Food Biomarker Alliance (funded by the European Joint Programming Initiative "A Healthy Diet for a Healthy Life" (JPI HDHL)) as well as points of reflections to harmonize this field. It is not intended to be exhaustive but rather to present a pragmatic guidance on metabolomic methodologies, providing readers with useful "tips and tricks" along the analytical workflow

The Frozen Commons: Possibilities and Limitations in International Environmental Development in the Russian Arctic

Thesis (Master's)--University of Washington, 2015This study relies on social science research on the causal mechanisms of capacity improvement to assess multilateral, environmental interventions in the Russian Arctic. The case studies reveal the occasions wherein target linking, commitment making, behavioral influence, and knowledge production played significant roles in influencing Russian institutions to take sustainable, environmental action. This theoretical basis enables an assessment of the Arctic Council’s unique use of knowledge production as a mechanism of influence. This assessment is achieved through a case study in the Council’s first and only major intervention into the Russian Arctic, the National Program of Action (NPA). Unlike other Council programs that coordinate multilateral research, the NPA tried to intervene directly into Russian policy-making by transferring the knowledge it generated into recommended regulations. However, none of these draft laws were ever passed. The study concludes that Russia accepts new environmental commitments, adapts its environmental targets, and acts on new knowledge when doing so intersects candidly with interests that are connected to Russian economics and defense

Human geography : people, place, and cultures

xiv, 399 p. : il.; 29 cm

Laser Item Identification System Development for a Laser Based Identification of UF6 Cylinders

Providing Continuity of Knowledge (CoK) on feed, product and tails material contained in UF6 cylinders that enter and exit enrichment plants has to date posed a substantial challenge to the IAEA. Control of the stored unsealed cylinders is also a challenge. Currently, these UF6 cylinders can only be manually identified by steel ID plates ¿ welded in place or riveted or bolted to the front of the cylinders ¿ unable to be authenticated by any reasonable method. The IAEA is testing a laser based method that identi-fies individual UF6 cylinders by the intrinsic spatial irregularities that are unique to each cylinder. The technique, developed by the European Joint Research Centre (JRC) in Ispra, has the potential to en-hance the Agency's ability to verify UF6 transfers. If proven feasible, the IAEA would incorporate this technique into unattended systems coupled with video surveillance.JRC.G.8-Nuclear safeguard