406 research outputs found

    Facts About the Great Plains Conservation Program in South Dakota

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    Know Your Land Program for South Dakota

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    A systematic study of the soil is the basic tool for determining the capabilities and limitations of land. Land judging is used to teach and promote a better understanding of soils through a study of the physical properties of the soil and to show how to use these properties in determining proper land use. Most of the characteristic. s that are used to identify soils can be determined in the field

    Genesis of ancestral haplotypes: RNA modifications and reverse transcription–mediated polymorphisms

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    Understanding the genesis of the block haplotype structure of the genome is a major challenge. With the completion of the sequencing of the Human Genome and the initiation of the HapMap project the concept that the chromosomes of the mammalian genome are a mosaic, or patchwork, of conserved extended block haplotype sequences is now accepted by the mainstream genomics research community. Ancestral Haplotypes (AHs) can be viewed as a recombined string of smaller Polymorphic Frozen Blocks (PFBs). How have such variant extended DNA sequence tracts emerged in evolution? Here the relevant literature on the problem is reviewed from various fields of molecular and cell biology particularly molecular immunology and comparative and functional genomics. Based on our synthesis we then advance a testable molecular and cellular model. A critical part of the analysis concerns the origin of the strand biased mutation signatures in the transcribed regions of the human and higher primate genome, A-to-G versus T-to-C (ratio ~1.5 fold) and C-to-T versus G-to-A (≥1.5 fold). A comparison and evaluation of the current state of the fields of immunoglobulin Somatic Hypermutation (SHM) and Transcription-Coupled DNA Repair focused on how mutations in newly synthesized RNA might be copied back to DNA thus accounting for some of the genome-wide strand biases (e.g., the A-to-G vs T-to-C component of the strand biased spectrum). We hypothesize that the genesis of PFBs and extended AHs occurs during mutagenic episodes in evolution (e.g., retroviral infections) and that many of the critical DNA sequence diversifying events occur first at the RNA level, e.g., recombination between RNA strings resulting in tandem and dispersed RNA duplications (retroduplications), RNA mutations via adenosine-to-inosine pre-mRNA editing events as well as error prone RNA synthesis. These are then copied back into DNA by a cellular reverse transcription process (also likely to be error-prone) that we have called "reverse transcription-mediated long DNA conversion." Finally we suggest that all these activities and others can be envisaged as being brought physically under the umbrella of special sites in the nucleus involved in transcription known as "transcription factories."

    Quasielastic Electron Scattering from Nuclei: Random-Phase vs. Ring Approximations

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    We investigate the extent to which the nuclear transverse response to electron scattering in the quasielastic region, evaluated in the random-phase approximation can be described by ring approximation calculations. Different effective interactions based on a standard model of the type g'+V_pi+V_rho are employed. For each momentum transfer, we have obtained the value of g'_0 permitting the ring response to match the position of the peak and/or the non-energy weighted sum rule provided by the random-phase approach has been obtained. It is found that, in general, it is not possible to reproduce both magnitudes simultaneously for a given g'_0 value.Comment: 7 pages, 4 Postscript figures, to appear in Physical Review

    STM observation of electronic wave interference effect in finite-sized graphite with dislocation-network structures

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    Superperiodic patterns near a step edge were observed by STM on several-layer-thick graphite sheets on a highly oriented pyrolitic graphite substrate, where a dislocation network is generated at the interface between the graphite overlayer and the substrate. Triangular- and rhombic-shaped periodic patterns whose periodicities are around 100 nm were observed on the upper terrace near the step edge. In contrast, only outlines of the patterns similar to those on the upper terrace were observed on the lower terrace. On the upper terrace, their geometrical patterns gradually disappeared and became similar to those on the lower terrace without any changes of their periodicity in increasing a bias voltage. By assuming a periodic scattering potential at the interface due to dislocations, the varying corrugation amplitudes of the patterns can be understood as changes in LDOS as a result of the beat of perturbed and unperturbed waves, i.e. the interference in an overlayer. The observed changes in the image depending on an overlayer height and a bias voltage can be explained by the electronic wave interference in the ultra-thin overlayer distorted under the influence of dislocation-network structures.Comment: 8 pages; 6 figures; Paper which a part of cond-mat/0311068 is disscussed in detai

    Phenomenology of the Deuteron Electromagnetic Form Factors

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    A rigorous extraction of the deuteron charge form factors from tensor polarization data in elastic electron-deuteron scattering, at given values of the 4-momentum transfer, is presented. Then the world data for elastic electron-deuteron scattering is used to parameterize, in three different ways, the three electromagnetic form factors of the deuteron in the 4-momentum transfer range 0-7 fm^-1. This procedure is made possible with the advent of recent polarization measurements. The parameterizations allow a phenomenological characterization of the deuteron electromagnetic structure. They can be used to remove ambiguities in the form factors extraction from future polarization data.Comment: 18 pages (LaTeX), 2 figures Feb. 25: minor changes of content and in Table

    Proton propagation in nuclei studied in the (e,e’p) reaction

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    Proton propagation in nuclei was studied using the (e,e’p) reaction in the quasifree region. The coincidence (e,e’p) cross sections were measured at an electron angle of 50.4° and proton angles of 50.1°, 58.2°, 67.9°, and 72.9° for 12C, 27Al, 58Ni, and 181Ta targets at a beam energy of 779.5 MeV. The average outgoing proton energy was 180 MeV. The ratio of the (e,e’p) yield to the simultaneously measured (e,e’) yield was compared to that calculated in the plane-wave impulse approximation and an experimental transmission defined. These experimental transmissions are considerably larger (a factor of ∼2 for 181Ta) than those one would calculate from the free N-N cross sections folded into the nuclear density distribution. A new calculation that includes medium effects (N-N correlations, density dependence of the N-N cross sections and Pauli suppression) accounts for this increase

    Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system.

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    Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection. One of the principal factors that control the outcome of infection is the localized tissue response and subsequent immune response directed against the invading toxic agent. It is the role of the immune system to contain and control the spread of virus infection in the central nervous system (CNS), and paradoxically, this response may also be pathologic. Chemokines are potent proinflammatory molecules whose expression within virally infected tissues is often associated with protection and/or pathology which correlates with migration and accumulation of immune cells. Indeed, studies with a neurotropic murine coronavirus, mouse hepatitis virus (MHV), have provided important insight into the functional roles of chemokines and chemokine receptors in participating in various aspects of host defense as well as disease development within the CNS. This chapter will highlight recent discoveries that have provided insight into the diverse biologic roles of chemokines and their receptors in coordinating immune responses following viral infection of the CNS

    Transverse Beam Spin Asymmetries in Forward-Angle Elastic Electron-Proton Scattering

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    We have measured the beam-normal single-spin asymmetry in elastic scattering of transversely-polarized 3 GeV electrons from unpolarized protons at Q^2 = 0.15, 0.25 (GeV/c)^2. The results are inconsistent with calculations solely using the elastic nucleon intermediate state, and generally agree with calculations with significant inelastic hadronic intermediate state contributions. A_n provides a direct probe of the imaginary component of the 2-gamma exchange amplitude, the complete description of which is important in the interpretation of data from precision electron-scattering experiments.Comment: 5 pages, 3 figures, submitted to Physical Review Letters; shortened to meet PRL length limit, clarified some text after referee's comment
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