The isotopic composition of precipitation from a winter storm – a case study with the limited-area model COSMO_iso

Stable water isotopes are valuable tracers of the atmospheric water cycle, and potentially provide useful information also on weather-related processes. In order to further explore this potential, the water isotopes H₂¹⁸O and HDO are incorporated into the limited-area model COSMO. In a first case study, the new COSMO_iso model is used for simulating a winter storm event in January 1986 over the eastern United States associated with intense frontal precipitation. The modelled isotope ratios in precipitation and water vapour are compared to spatially distributed &delta;</sub>¹⁸O observations. COSMO_iso very accurately reproduces the statistical distribution of &delta;</sub>¹⁸O in precipitation, and also the synoptic-scale spatial pattern and temporal evolution agree well with the measurements. Perpendicular to the front that triggers most of the rainfall during the event, the model simulates a gradient in the isotopic composition of the precipitation, with high &delta;</sub>¹⁸O values in the warm air and lower values in the cold sector behind the front. This spatial pattern is created through an interplay of large scale air mass advection, removal of heavy isotopes by precipitation at the front and microphysical interactions between rain drops and water vapour beneath the cloud base. This investigation illustrates the usefulness of high resolution, event-based model simulations for understanding the complex processes that cause synoptic-scale variability of the isotopic composition of atmospheric waters. In future research, this will be particularly beneficial in combination with laser spectrometric isotope observations with high temporal resolution

A case study on the formation and evolution of ice supersaturation in the vicinity of a warm conveyor belt's outflow region

A case study is presented on the formation and evolution of an ice-supersaturated region (ISSR) that was detected by a radiosonde in NE Germany at 06:00&nbsp;UTC 29 November 2000. The ISSR was situated in the vicinity of the outflow region of a warm conveyor belt associated with an intense event of cyclogenesis in the eastern North Atlantic. Using ECMWF analyses and trajectory calculations it is determined when the air parcels became supersaturated and later subsaturated again. In the case considered, the state of air parcel supersaturation can last for longer than 24h. The ISSR was unusually thick: while the mean vertical extension of ISSRs in NE Germany is about 500m, the one investigated here reached 3km. The ice-supersaturated region investigated was bordered both vertically and horizontally by strongly subsaturated air. Near the path of the radiosonde the ISSR was probably cloud free, as inferred from METEOSAT infrared images. However, at other locations within the ISSR it is probable that there were cirrus clouds. Relative humidity measurements obtained by the Lindenberg radiosonde are used to correct the negative bias of the ECMWF humidity and to construct two-dimensional maps of ice supersaturation over Europe during the considered period. A systematic backward trajectory analysis for the ISSRs on these maps shows that the ISSR air masses themselves experienced only a moderate upward motion during the previous days, whereas parts of the ISSRs were located just above strongly ascending air masses from the boundary layer. This indicates qualitatively that warm conveyor belts associated with mid-latitude cyclogenesis are disturbances that can induce the formation of ISSRs in the upper troposphere. The ISSR maps also lead us to a new perception of ISSRs as large dynamic regions of supersaturated air where cirrus clouds can be embedded at some locations while there is clear air at others

Running quietly reduces ground reaction force and vertical loading rate and alters foot strike technique

This study aimed to determine if a quantifiable relationship exists between the peak sound amplitude and peak vertical ground reaction force (vGRF) and vertical loading rate during running. It also investigated whether differences in peak sound amplitude, contact time, lower limb kinematics, kinetics and foot strike technique existed when participants were verbally instructed to run quietly compared to their normal running. A total of 26 males completed running trials for two sound conditions: normal running and quiet running. Simple linear regressions revealed no significant relationships between impact sound and peak vGRF in the normal and quiet conditions and vertical loading rate in the normal condition. t-Tests revealed significant within-subject decreases in peak sound, peak vGRF and vertical loading rate during the quiet compared to the normal running condition. During the normal running condition, 15.4% of participants utilised a non-rearfoot strike technique compared to 76.9% in the quiet condition, which was corroborated by an increased ankle plantarflexion angle at initial contact. This study demonstrated that quieter impact sound is not directly associated with a lower peak vGRF or vertical loading rate. However, given the instructions to run quietly, participants effectively reduced peak impact sound, peak vGRF and vertical loading rate

OASIS High-Resolution Integral Field Spectroscopy of the SAURON Ellipticals and Lenticulars

We present a summary of high-spatial resolution follow-up observations of the elliptical (E) and lenticular (S0) galaxies in the SAURON survey using the OASIS integral field spectrograph. The OASIS observations explore the central 8x10" regions of these galaxies using a spatial sampling four times higher than SAURON, often revealing previously undiscovered features. Around 75% (31/48) of the SAURON E/S0s with central velocity dispersion >= 120 km/s were observed with OASIS, covering well the original SAURON representative sample. We present here an overview of this follow-up survey, and some preliminary results on individual objects, including a previously unreported counter-rotating core in NGC 4382; the decoupled stellar and gas velocity fields of NGC 2768; and the strong age gradient towards the centre of NGC 3489.Comment: 4 pages, 5 figures. Accepted for publication in Astron. Nachr. as refereed proceedings of Euro3D Science Workshop, IoA Cambridge, May 200

Ultrathin Tropical Tropopause Clouds (UTTCs) : I. Cloud morphology and occurrence

Subvisible cirrus clouds (SVCs) may contribute to dehydration close to the tropical tropopause. The higher and colder SVCs and the larger their ice crystals, the more likely they represent the last efficient point of contact of the gas phase with the ice phase and, hence, the last dehydrating step, before the air enters the stratosphere. The first simultaneous in situ and remote sensing measurements of SVCs were taken during the APE-THESEO campaign in the western Indian ocean in February/March 1999. The observed clouds, termed Ultrathin Tropical Tropopause Clouds (UTTCs), belong to the geometrically and optically thinnest large-scale clouds in the Earth´s atmosphere. Individual UTTCs may exist for many hours as an only 200--300 m thick cloud layer just a few hundred meters below the tropical cold point tropopause, covering up to 105 km2. With temperatures as low as 181 K these clouds are prime representatives for defining the water mixing ratio of air entering the lower stratosphere

Extremely high velocity gas from the massive YSOs in IRAS 17233-3606

Molecular outflows from high-mass young stellar objects provide an excellent way to study the star formation process, and investigate if they are scaled-up versions of their low-mass counterparts. We selected the nearby massive star forming region IRAS 17233-3606 in order to study the kinematics and physics along the molecular outflow(s) originating from this source. We observed IRAS 17233-3606 in CO, a typical tracer of gas associated with molecular outflow, with the Submillimeter Array in the (2-1) transition, and with the APEX telescope in the higher excitation (6-5) line. Additional infrared H2 observations were performed with the UKIRT telescope. The CO data were analysed using a LVG approach. Our data resolve the previously detected molecular outflow in at least three different components, one of them with a high collimation factor ~4, and characterised by emission at extremely high velocities (|v-v_{LSR}|>120 km s^{-1}). The estimate of the kinematical outflow parameters are typical of massive YSOs, and in agreement with the measured bolometric luminosity of the source. The kinematic ages of the flows are in the range 10^2-10^3 yr, and therefore point to young objects that still did not reach the main sequence.Comment: accepted for publication in A&

Warm conveyor belt activity over the Pacific: modulation by the Madden–Julian Oscillation and impact on tropical–extratropical teleconnections

Research in the last few decades has revealed that rapidly ascending airstreams in extratropical cyclones – so-called warm conveyor belts (WCBs) – play an important role in extratropical atmospheric dynamics. However on the subseasonal timescale, the modulation of their occurrence frequency, henceforth referred to as WCB activity, has so far received little attention. Also, it is not yet clear whether WCB activity may affect tropospheric teleconnection patterns, which constitute a source of predictability on this subseasonal timescale. Using reanalysis data, this study analyzes the modulation of WCB activity by the Madden–Julian Oscillation (MJO). A key finding is that WCB activity increases significantly over the western North Pacific when the convection of the MJO is located over the Indian Ocean. This increased WCB activity, which is stronger during La Niña conditions, is related to enhanced poleward moisture fluxes driven by the circulation of subtropical Rossby gyres associated with the MJO. In contrast, when the convection of the MJO is located over the western North Pacific, WCB activity increases significantly over the eastern North Pacific. This increase stems from a southward shift and eastward extension of the North Pacific jet stream. However, while these mean increases are significant, individual MJO events exhibit substantial variability, with some events even exhibiting anomalously low WCB activity. Individual events of the same MJO phase with anomalously low WCB activity over the North Pacific tend to be followed by the known canonical teleconnection patterns in the Atlantic–European region; i.e., the occurrence frequency of the positive phase of the North Atlantic Oscillation (NAO) is enhanced when convection of the MJO is located over the Indian Ocean and similarly for the negative phase of the NAO when MJO convection is over the western North Pacific. However, the canonical teleconnection patterns are modified when individual events of the same MJO phase are accompanied by anomalously high WCB activity over the North Pacific. In particular, the link between MJO and the negative phase of the NAO weakens considerably. Reanalysis data and experiments with an idealized general circulation model reveal that this is related to anomalous ridge building over western North America favored by enhanced WCB activity. Overall, our study highlights the potential role of WCBs in shaping tropical–extratropical teleconnection patterns and underlines the importance of representing them adequately in numerical weather prediction models in order to fully exploit the sources of predictability emerging from the tropics.</p

Single agent rituximab in patients with follicular or mantle cell lymphoma: clinical and biological factors that are predictive of response and event-free survival as well as the effect of rituximab on the immune system: a study of the Swiss Group for Clinical Cancer Research (SAKK)

Background: Predictive factors of rituximab efficacy and its effect on the immune system are still not defined. Patients and methods: Three hundred and six patients with follicular or mantle cell lymphoma received four weekly doses of rituximab (induction) and no further treatment (arm A) or four more doses at 2-month intervals (arm B). Results: Response rate to induction was 44%. Independent predictive factors for response were disease bulk <5 cm, follicular histology, normal hemoglobin and low lymphocyte count. Factors associated with event-free survival (EFS) were having responded to induction, having received not more than one line of therapy, Ann Arbor stage I-III, high lymphocyte count, disease bulk <5 cm, Fc-gamma receptor genotype VV and receiving prolonged treatment. B cells were suppressed by treatment but recovered after a median of 12 months in arm A and 18 months in arm B. The median IgM level after 1 year was normal in arm A but was decreased to 73% of baseline in arm B. We observed 24 serious adverse events, equally distributed between arms. Ten patients receiving induction only and six patients receiving prolonged treatment developed a second tumor. Conclusions: We defined the characteristics predicting response and EFS to rituximab. Prolonged treatment results in longer EFS at the cost of a longer reduction in B cell and IgM levels, but without additional clinical toxicit

Kilometer-scale climate models: Prospects and challenges

Currently major efforts are underway toward refining the horizontal resolution (or grid spacing) of climate models to about 1 km, using both global and regional climate models (GCMs and RCMs). Several groups have succeeded in conducting kilometer-scale multiweek GCM simulations and decadelong continental-scale RCM simulations. There is the well-founded hope that this increase in resolution represents a quantum jump in climate modeling, as it enables replacing the parameterization of moist convection by an explicit treatment. It is expected that this will improve the simulation of the water cycle and extreme events and reduce uncertainties in climate change projections. While kilometer-scale resolution is commonly employed in limited-area numerical weather prediction, enabling it on global scales for extended climate simulations requires a concerted effort. In this paper, we exploit an RCM that runs entirely on graphics processing units (GPUs) and show examples that highlight the prospects of this approach. A particular challenge addressed in this paper relates to the growth in output volumes. It is argued that the data avalanche of high-resolution simulations will make it impractical or impossible to store the data. Rather, repeating the simulation and conducting online analysis will become more efficient. A prototype of this methodology is presented. It makes use of a bit-reproducible model version that ensures reproducible simulations across hardware architectures, in conjunction with a data virtualization layer as a common interface for output analyses. An assessment of the potential of these novel approaches will be provided

The cometary composition of a protoplanetary disk as revealed by complex cyanides

Observations of comets and asteroids show that the Solar Nebula that spawned our planetary system was rich in water and organic molecules. Bombardment brought these organics to the young Earth's surface, seeding its early chemistry. Unlike asteroids, comets preserve a nearly pristine record of the Solar Nebula composition. The presence of cyanides in comets, including 0.01% of methyl cyanide (CH3CN) with respect to water, is of special interest because of the importance of C-N bonds for abiotic amino acid synthesis. Comet-like compositions of simple and complex volatiles are found in protostars, and can be readily explained by a combination of gas-phase chemistry to form e.g. HCN and an active ice-phase chemistry on grain surfaces that advances complexity[3]. Simple volatiles, including water and HCN, have been detected previously in Solar Nebula analogues - protoplanetary disks around young stars - indicating that they survive disk formation or are reformed in situ. It has been hitherto unclear whether the same holds for more complex organic molecules outside of the Solar Nebula, since recent observations show a dramatic change in the chemistry at the boundary between nascent envelopes and young disks due to accretion shocks[8]. Here we report the detection of CH3CN (and HCN and HC3N) in the protoplanetary disk around the young star MWC 480. We find abundance ratios of these N-bearing organics in the gas-phase similar to comets, which suggests an even higher relative abundance of complex cyanides in the disk ice. This implies that complex organics accompany simpler volatiles in protoplanetary disks, and that the rich organic chemistry of the Solar Nebula was not unique.Comment: Definitive version of the manuscript is published in Nature, 520, 7546, 198, 2015. This is the author's versio