Error Signals from the Brain: 7th Mismatch Negativity Conference

The 7th Mismatch Negativity Conference presents the state of the art in methods, theory, and application (basic and clinical research) of the MMN (and related error signals of the brain). Moreover, there will be two pre-conference workshops: one on the design of MMN studies and the analysis and interpretation of MMN data, and one on the visual MMN (with 20 presentations). There will be more than 40 presentations on hot topics of MMN grouped into thirteen symposia, and about 130 poster presentations. Keynote lectures by Kimmo Alho, Angela D. Friederici, and Israel Nelken will round off the program by covering topics related to and beyond MMN

Specifications of Standards in Systems and Synthetic Biology

Standards shape our everyday life. From nuts and bolts to electronic devices and technological processes, standardised products and processes are all around us. Standards have technological and economic benefits, such as making information exchange, production, and services more efficient. However, novel, innovative areas often either lack proper standards, or documents about standards in these areas are not available from a centralised platform or formal body (such as the International Standardisation Organisation)

Error Signals from the Brain: 7th Mismatch Negativity Conference

The 7th Mismatch Negativity Conference presents the state of the art in methods, theory, and application (basic and clinical research) of the MMN (and related error signals of the brain). Moreover, there will be two pre-conference workshops: one on the design of MMN studies and the analysis and interpretation of MMN data, and one on the visual MMN (with 20 presentations). There will be more than 40 presentations on hot topics of MMN grouped into thirteen symposia, and about 130 poster presentations. Keynote lectures by Kimmo Alho, Angela D. Friederici, and Israel Nelken will round off the program by covering topics related to and beyond MMN

Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency

The occurrence of neurological symptoms and developmental delay in patients affected by congenital hypothyroidism (CH) has been attributed to the lack of thyroid hormone in the developing CNS. Accordingly, after the introduction of neonatal screening programs for CH, which allowed early and adequate treatment, an almost normal outcome for most CH patients could be achieved. However, a few patients did not reach this favorable outcome despite early and adequate treatment. Here we describe five patients with variable degrees of CH who suffered from choreoathetosis, muscular hypotonia, and pulmonary problems, an association of symptoms that had not been described before this study. Since this clinical picture matched the phenotype of mice targeted for deletion of the transcription factor gene Nkx2-1, we investigated the human NKX2-1 gene in these five patients. We found heterozygous loss of function mutations in each of these five patients, e.g., one complete gene deletion, one missense mutation (G2626T), and three nonsense mutations (2595insGG, C2519A, C1302A). Therefore, the unfavorable outcome in patients with CH, especially those with choreoathetosis and pulmonary symptoms, can be explained by mutations in the NKX2-1 gene rather than by hypothyroidism. Moreover, the association of symptoms in the patients with NKX2-1 mutations points to an important role of human NKX2-1 in the development and function of thyroid, basal ganglia, and lung, as already described for rodents

Festschrift für Prof. Dr. Dagmar Blei

Softcover, 17x24Obwohl Deutsch als Fremd- und Zweitsprache (DaF/DaZ) ein verhältnismäßig junges Fach ist, ist es doch alt genug, um bereits über drei Geschichten zu verfügen: eine ostdeutsche, eine westdeutsche und eine gesamtdeutsche. Die Erforschung dieser drei Geschichten samt ihrer spannungsreichen (Nicht-)Bezüge und Bezugnahmen hat gerade erst begonnen. Im vorliegenden Band liegt der Fokus auf dem DaF/DaZ-Standort Dresden und seiner Fachvertreterin Prof. Dr. Dagmar Blei, die diesen Übergang maßgeblich gestaltet hat; ihr ist dieser Band gewidmet. Anhand von berufsbiographischen Reflexionen ihrer ehemaligen Mitarbeiter*innen sowie von Rückblicken ehemaliger Kolleg*innen werden nicht nur der Übergang von der ostdeutschen Teilgeschichte in die gesamtdeutsche Geschichte des Faches, sondern auch einige seiner Teilbereiche exemplarisch beleuchtet. Dabei geht es nie nur um die Vergangenheit, sondern immer auch um die Zukunftsperspektiven des Faches an der TU Dresden und darüber hinaus.Although German as a Foreign and Second Language (DaF/DaZ) is a relatively young subject, it is old enough to already have three histories: one East German, one West German, and one all-German. The exploration of these three histories including their tense (non)references and references has only just begun. In the present volume, the focus is on the DaF/DaZ location Dresden and its subject representative Prof. Dr. Dagmar Blei, who played a decisive role in shaping this transition. this volume is dedicated to her. On the basis of professional biographical reflexions of her former staff members as well as retrospectives of former colleagues, not only the transition from the East German partial history to the all-German history of the The subject's transition from the East German partial history to the history of the whole of Germany, but also some of its sub-areas, are illuminated in an exemplary manner. The focus is never only on the past, but also on the future perspectives of the subject at the TU Dresden and beyond. Translated with www.DeepL.com/Translator (free version

Plato argénteo nº 38.215 . Cabeza antropomorfa diademada - ABE0162_AR

Proyectos del Plan Nacional I+D+I con referencias PB94-0129, PB97-1132, BHA 2002-00138, HUM 2006-06250/HISTProyectos de la CAM con referencias 06/0020/1997, 06/0094/1998, 06/0090/2000, 06/0043/2001Programa Consolider-Ingenio 2010 con sigla CSD2007-00058NoMuseo Arqueológico Nacional (Madrid)AbengibrePlato argénteo nº 38.215 . Cabeza antropomorfa diademad