The conformal boundary states for SU(2) at level 1

For the case of the SU(2) WZW model at level one, the boundary states that only preserve the conformal symmetry are analysed. Under the assumption that the usual Cardy boundary states as well as their marginal deformations are consistent, the most general conformal boundary states are determined. They are found to be parametrised by group elements in SL(2,C).Comment: 22 pages, harvmac (b), 5 figure

Extended multiplet structure in Logarithmic Conformal Field Theories

We use the process of quantum hamiltonian reduction of SU(2)_k, at rational level k, to study explicitly the correlators of the h_{1,s} fields in the c_{p,q} models. We find from direct calculation of the correlators that we have the possibility of extra, chiral and non-chiral, multiplet structure in the h_{1,s} operators beyond the `minimal' sector. At the level of the vacuum null vector h_{1,2p-1}=(p-1)(q-1) we find that there can be two extra non-chiral fermionic fields. The extra indicial structure present here permeates throughout the entire theory. In particular we find we have a chiral triplet of fields at h_{1,4p-1}=(2p-1)(2q-1). We conjecture that this triplet algebra may produce a rational extended c_{p,q} model. We also find a doublet of fields at h_{1,3p-1}=(\f{3p}{2}-1)(\f{3q}{2}-1). These are chiral fermionic operators if p and q are not both odd and otherwise parafermionic.Comment: 24 pages LATEX. Minor corrections and extra reference

Unitarity of rational N=2 superconformal theories

We demonstrate that all rational models of the N=2 super Virasoro algebra are unitary. Our arguments are based on three different methods: we determine Zhu's algebra (for which we give a physically motivated derivation) explicitly for certain theories, we analyse the modular properties of some of the vacuum characters, and we use the coset realisation of the algebra in terms of su_2 and two free fermions. Some of our arguments generalise to the Kazama-Suzuki models indicating that all rational N=2 supersymmetric models might be unitary.Comment: LaTeX (+amssym.def), 28 pages; minor changes in content, some references added, final versio

Localization of quasiparticles in a disordered vortex

We study the diffusive motion of low-energy normal quasiparticles along the core of a single vortex in a dirty, type-II, s-wave superconductor. The physics of this system is argued to be described by a one-dimensional supersymmetric nonlinear sigma model, which differs from the sigma models known for disordered metallic wires. For an isolated vortex and quasiparticle energies less than the Thouless energy, we recover the spectral correlations that are predicted by random matrix theory for the universality class C. We then consider the transport problem of transmission of quasiparticles through a vortex connected to particle reservoirs at both ends. The transmittance at zero energy exhibits a weak localization correction reminiscent of quasi-one-dimensional metallic systems with symmetry index beta = 1. Weak localization disappears with increasing energy over a scale set by the Thouless energy. This crossover should be observable in measurements of the longitudinal heat conductivity of an ensemble of vortices under mesoscopic conditions. In the regime of strong localization, the localization length is shown to decrease by a factor of 8 as the quasiparticle energy goes to zero.Comment: 38 pages, LaTeX2e + epsf, 4 eps figures, one reference adde

Iodine source apportionment in the Malawian diet

The aim of this study was to characterise nutritional-I status in Malawi. Dietary-I intakes were assessed using new datasets of crop, fish, salt and water-I concentrations, while I status was assessed for 60 women living on each of calcareous and non-calcareous soils as defined by urinary iodine concentration (UIC). Iodine concentration in staple foods was low, with median concentrations of 0.01 mg kg−1 in maize grain, 0.008 mg kg−1 in roots and tubers, but 0.155 mg kg−1 in leafy vegetables. Freshwater fish is a good source of dietary-I with a median concentration of 0.51 mg kg−1. Mean Malawian dietary-Iodine intake from food, excluding salt, was just 7.8 μg d−1 compared to an adult requirement of 150 μg d−1. Despite low dietary-I intake from food, median UICs were 203 μg L−1 with only 12% defined as I deficient whilst 21% exhibited excessive I intake. Iodised salt is likely to be the main source of dietary I intake in Malawi; thus, I nutrition mainly depends on the usage and concentration of I in iodised salt. Drinking water could be a significant source of I in some areas, providing up to 108 μg d−1 based on consumption of 2 L d−1

Tracking Parkinson's Disease over One Year with Multimodal Magnetic Resonance Imaging in a Group of Older Patients with Moderate Disease

Background & Objectives: Cross-sectional magnetic resonance imaging (MRI) suggests that Parkinson’s disease (PD) is associated with changes in cerebral tissue volume, diffusion tensor imaging metrics, and perfusion values. Here, we performed a longitudinal multimodal MRI study—including structural, diffusion tensor imaging (DTI), and perfusion MRI—to investigate progressive brain changes over one year in a group of older PD patients at a moderate stage of disease

Pharmacologic intervention for prevention of fractures in osteopenic and osteoporotic postmenopausal women: Systemic review and meta-analysis

Objectives Emerging evidence has indicated a role for pharmacologic agents in the primary prevention of osteoporotic fracture, but have not yet been systematically reviewed for meta-analysis. We conducted a meta-analysis to evaluate the efficacy of pharmacologic interventions in reducing fracture risk and increasing bone mineral density (BMD) in postmenopausal women with osteopenia or osteoporosis but without prevalent fragility fracture. Method The Medline, EMBASE, and CENTRAL databases were searched from inception to September 30, 2019. Only randomized placebo-controlled trials evaluating postmenopausal women with −1.0 > bone mineral density (BMD) T-score > −2.5 (low bone mass) and those with BMD T-score ≤ −2.5 (osteoporosis) but without baseline fractures, who were receiving anti-osteoporotic agents, providing quantitative outcomes data and evaluating risk of vertebral and/or non-vertebral fragility fracture at follow-up. The PRISMA guidelines were followed, applying a random-effects model. The primary endpoint was the effect of anti-osteoporotic regimens in reducing the incidence of vertebral fractures. Secondary endpoints were percentage changes in baseline BMD at the lumbar spine and total hip at 1 and 2 years follow up. Results Full-text review of 144 articles yielded, 20 for meta-analysis. Bisphosphonates reduced the risk of vertebral fracture (pooled OR = 0.50, 95%CIs = 0.36–0.71) and significantly increased lumbar spine BMD after 1 year, by 4.42% vs placebo (95%CIs = 3.70%–5.14%). At the hip, this value was 2.94% (95%CIs = 2.13%–3.75%). Overall results of limited studies for non-bisphosphonate drugs showed increased BMD and raloxifene significantly decreases the risk of subsequent clinical vertebral fractures. Conclusion The bisphosphonates are efficacious and most evident for the primary prevention of osteoporotic vertebral fractures, reducing their incidence and improving BMD in postmenopausal women with osteopenia or osteoporosis

A Bayesian analysis of pentaquark signals from CLAS data

We examine the results of two measurements by the CLAS collaboration, one of which claimed evidence for a $\Theta^{+}$ pentaquark, whilst the other found no such evidence. The unique feature of these two experiments was that they were performed with the same experimental setup. Using a Bayesian analysis we find that the results of the two experiments are in fact compatible with each other, but that the first measurement did not contain sufficient information to determine unambiguously the existence of a $\Theta^{+}$. Further, we suggest a means by which the existence of a new candidate particle can be tested in a rigorous manner.Comment: 5 pages, 3 figure

Quantifying atherogenic lipoproteins for lipid-lowering strategies : Consensus-based recommendations from EAS and EFLM

The joint consensus panel of the European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) recently addressed present and future challenges in the laboratory diagnostics of atherogenic lipoproteins. Total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, and calculated non-HDL cholesterol (= total - HDL cholesterol) constitute the primary lipid panel for estimating risk of atherosclerotic cardiovascular disease (ASCVD) and can be measured in the nonfasting state. LDL cholesterol is the primary target of lipid-lowering therapies. For on-treatment follow-up, LDL cholesterol shall be measured or calculated by the same method to attenuate errors in treatment decisions due to marked between-method variations. Lipoprotein(a)-cholesterol is part of measured or calculated LDL cholesterol and should be estimated at least once in all patients at risk of ASCVD, especially in those whose LDL cholesterol decline poorly upon statin treatment. Residual risk of ASCVD even under optimal LDL-lowering treatment should be also assessed by non-HDL cholesterol or apolipoprotein B, especially in patients with mild-to-moderate hypertriglyceridemia (2-10 mmol/L). Non-HDL cholesterol includes the assessment of remnant lipoprotein cholesterol and shall be reported in all standard lipid panels. Additional apolipoprotein B measurement can detect elevated LDL particle numbers often unidentified on the basis of LDL cholesterol alone. Reference intervals of lipids, lipoproteins, and apolipoproteins are reported for European men and women aged 20-100 years. However, laboratories shall flag abnormal lipid values with reference to therapeutic decision thresholds.Peer reviewe

First measurement of direct f0(980)f_0(980) photoproduction on the proton

We report on the results of the first measurement of exclusive $f_0(980)$ meson photoproduction on protons for $E_\gamma=3.0 - 3.8$ GeV and $-t = 0.4-1.0$ GeV$^2$. Data were collected with the CLAS detector at the Thomas Jefferson National Accelerator Facility. The resonance was detected via its decay in the $\pi^+ \pi^-$ channel by performing a partial wave analysis of the reaction $\gamma p \to p \pi^+ \pi^-$. Clear evidence of the $f_0(980)$ meson was found in the interference between $P$ and $S$ waves at $M_{\pi^+ \pi^-}\sim 1$ GeV. The $S$-wave differential cross section integrated in the mass range of the $f_0(980)$ was found to be a factor of 50 smaller than the cross section for the $\rho$ meson. This is the first time the $f_0(980)$ meson has been measured in a photoproduction experiment