Efficacy and safety of travoprost 0.004% compared with tafluprost 0.0015% in patients with primary open-angle glaucoma

Background: This prospective, open, randomized, parallel-group, comparative study is to evaluate the efficacy and side-effect profile of travoprost (TRAV) 0.004% compared with tafluprost (TAF) 0.0015% in patients with primary open-angle glaucoma (POAG) over 12 weeks. A total of 80 patients of POAG selected and were randomized to either TRAV or TAF monotherapy administered once daily in the evening for 12 weeks.Methods: The study was conducted on 80 cases of POAG, in which patients were randomized to either TRAV or TAF monotherapy administered as 1 drop daily in the evening for 12 weeks. Intraocular pressure (IOP) was measured (8 am, 12 noon and 4 pm) at each visit, slit-lamp bio-microscopy was done and side effects noted.Results: The mean IOP reduction in TRAV group decreased from 27.58±2.30 to 19.03±2.326 thus resulting in fall of 8.55 (31.0%) and in TAF group it decreased from 27.38±2.676 to 20.58±2.827 resulting in fall of 6.8 mm Hg (24.8%) was significant (p<0.05). In both treatment groups, the most frequently reported adverse event at 12 weeks was red eye, noted in, 9 (22.5%) and 7 (17.5%) cases of TRAV and TAF groups respectively, though the difference was not statistically significant.Conclusion: TRAV 0.004% monotherapy produced lower diurnal IOP than TAF 0.0015% in patients with POAG and exhibited a similar safety profile

Electrochemo-magneto abrasive flow machine setup fabrication and experimental investigation of the process alongwith mathematical modeling and optimization

In abrasive flow machining, there are two sets of piston-cylinder arrangements, i.e. machine and media. the machine ram pushes the media piston two and fro so that media filled inside it flows past the inner wall of workpiece and the material is removed. The extrusion pressure is the main mechanism of material removal. Various authors have made the process more effective in terms of material removal and surface roughness by providing rotational and magnetic force

Electrochemo-magneto abrasive flow machine setup fabrication and experimental investigation of the process alongwith mathematical modeling and optimization

In abrasive flow machining, there are two sets of piston-cylinder arrangements, i.e. machine and media. the machine ram pushes the media piston two and fro so that media filled inside it flows past the inner wall of workpiece and the material is removed. The extrusion pressure is the main mechanism of material removal. Various authors have made the process more effective in terms of material removal and surface roughness by providing rotational and magnetic force

Abstracts of International Conference on Innovations in Business Management

This book contains abstracts of the various research ideas of the academic community and practitioners of management presented at the International Conference on Innovations in Business Management (ICIBM 2020). The researchers have contributed toward various themes of the conference such as sustainable economy, supply chain, women-empowerment, export-import, microfinance, government policies, etc. We strongly believe that it will open up further scope for in-depth research in various disciplines of business management. Best wishes to the participants to have detailed discussions on the above-said wide range of areas. Conference Title: International Conference on Innovations in Business ManagementConference Acronym: ICIBM 2020Conference Date: 16-17 January 2020Conference Location: ICFAI University, Dehradun, IndiaConference Organizers: ICFAI Business School, ICFAI University, Dehradun, India &amp; University of Derby, United Kingdo