Kinetic-Ion Simulations Addressing Whether Ion Trapping Inflates Stimulated Brillouin Backscattering Reflectivities

An investigation of the possible inflation of stimulated Brillouin backscattering (SBS) due to ion kinetic effects is presented using electromagnetic particle simulations and integrations of three-wave coupled-mode equations with linear and nonlinear models of the nonlinear ion physics. Electrostatic simulations of linear ion Landau damping in an ion acoustic wave, nonlinear reduction of damping due to ion trapping, and nonlinear frequency shifts due to ion trapping establish a baseline for modeling the electromagnetic SBS simulations. Systematic scans of the laser intensity have been undertaken with both one-dimensional particle simulations and coupled-mode-equations integrations, and two values of the electron-to-ion temperature ratio (to vary the linear ion Landau damping) are considered. Three of the four intensity scans have evidence of SBS inflation as determined by observing more reflectivity in the particle simulations than in the corresponding three-wave mode-coupling integrations with a linear ion-wave model, and the particle simulations show evidence of ion trapping.Comment: 56 pages, 20 figure

Differential diagnosis of dna viruses related to reproductive disorder on sows by multiplex-pcr technique

The newly emerged diseases caused by ASFV and PCV3 and their confirmed prevelance in Vietnam whereas most of available common commercial methods such as ELISA or realtime PCR designed for detecting single pathogen per reaction, highlighted a necessity for another diagnostic method to simultaneously detect and differentiate DNA viruses that are related to reproductive failures in sow herds including PCV2, PCV3, PPV, ASFV. In this communication, a diagnostic multiplex-PCR (mPCR) was established with pathogen-specific primers selected from previous studies and another set of primers designed for COX1 gene serving as an internal amplification control (IAC). The predicted products of PCV2, PCV3, PPV, ASFV and IAC were 702 bp, 223 bp, 380 bp, 278 bp and 463 bp, respectively. After optimization, the mPCR functioned specifically at 62°C. Results revealed the consistent detection limit at 100 copies/gene/reaction. In application, 185 serum samples from sows were used to examine the presence of the related pathogens. mPCR results showed that the mono-infection rate of PCV2, PCV3, PPV, and ASFV was 0% (0/185), 40% (74/185), 28.1% (52/185), and 48.1% (89/185), respectively. Regarding coinfection rate, the data indicated that coinfections of 2, 3 and 4 pathogens were 20%, 8.1% and 0% accordingly. In conclusion, the mPCR assay was successfully established and ready to serve for diagnosis of PCV2, PCV3, PPV and ASFV infection in reality with high specificity and sensitivity. It is a good contribution to a better understanding of the epidemiology of these diseases in swine

Sensor development and readout prototyping for the STAR Pixel detector

The STAR experiment at the Relativistic Heavy Ion Collider (RHIC) is designing a new vertex detector. The purpose of this upgrade detector is to provide high resolution pointing to allow for the direct topological reconstruction of heavy flavor decays such as the D{sup 0} by finding vertices displaced from the collision vertex by greater than 60 microns. We are using Monolithic Active Pixel Sensor (MAPS) as the sensor technology and have a coupled sensor development and readout system plan that leads to a final detector with a <200 {micro}s integration time, 400 M pixels and a coverage of -1 < {eta} < 1. We present our coupled sensor and readout development plan and the status of the prototyping work that has been accomplished

Theory of the optical absorption of light carrying orbital angular momentum by semiconductors

We develop a free-carrier theory of the optical absorption of light carrying orbital angular momentum (twisted light) by bulk semiconductors. We obtain the optical transition matrix elements for Bessel-mode twisted light and use them to calculate the wave function of photo-excited electrons to first-order in the vector potential of the laser. The associated net electric currents of first and second-order on the field are obtained. It is shown that the magnetic field produced at the center of the beam for the $\ell=1$ mode is of the order of a millitesla, and could therefore be detected experimentally using, for example, the technique of time-resolved Faraday rotation.Comment: Submitted to Phys. Rev. Lett. (23 Jan 2008

Quantum Monte Carlo Evidence for d-wave Pairing in the 2D Hubbard Model at a van Hove Singularity

We implement a Quantum Monte Carlo calculation for a repulsive Hubbard model with nearest and next-nearest neighbor hopping interactions on clusters up to 12x12. A parameter region where the Fermi level lies close to the van Hove singularity at the Saddle Points in the bulk band structure is investigated. A pairing tendency in the $d_{x^2-y^2}$ symmetry channel, but no other channel, is found. Estimates of the effective pairing interaction show that it is close to the value required for a 40 K superconductor. Finite-size scaling compares with the attractive Hubbard model.Comment: 11 pages, REVTex, 4 figures, postscrip

A Contractor Based on Convex Interval Taylor

International audienceInterval Taylor has been proposed in the sixties by the interval analysis community for relaxing continuous non-convex constraint systems. However, it generally produces a non-convex relaxation of the solution set. A simple way to build a convex polyhedral relaxation is to select a corner of the studied domain/box as expansion point of the interval Taylor form, instead of the usual midpoint. The idea has been proposed by Neumaier to produce a sharp range of a single function andby Lin and Stadtherr to handle n × n (square) systems of equations. This paper presents an interval Newton-like operator, called X-Newton, that iteratively calls this interval convexification based on an endpoint interval Taylor. This general-purpose contractor uses no preconditioning and can handle any system of equality and inequality constraints. It uses Hansen's variant to compute the interval Taylor form and uses two opposite corners of the domain for every constraint. The X-Newton operator can be rapidly encoded, and produces good speedups in constrained global optimization and constraint satisfaction. First experiments compare X-Newton with affine arithmetic

Role of Esrrg in the Fibrate-Mediated Regulation of Lipid Metabolism Genes in Human ApoA-I Transgenic Mice

We have used a new ApoA-I transgenic mouse model to identify by global gene expression profiling, candidate genes that affect lipid and lipoprotein metabolism in response to fenofibrate treatment. Multilevel bioinformatical analysis and stringent selection criteria (2-fold change, 0% false discovery rate) identified 267 significantly changed genes involved in several molecular pathways. The fenofibrate-treated group did not have significantly altered levels of hepatic human APOA-I mRNA and plasma ApoA-I compared with the control group. However, the treatment increased cholesterol levels to 1.95-fold mainly due to the increase in high-density lipoprotein (HDL) cholesterol. The observed changes in HDL are associated with the upregulation of genes involved in phospholipid biosynthesis and lipid hydrolysis, as well as phospholipid transfer protein. Significant upregulation was observed in genes involved in fatty acid transport and β-oxidation, but not in those of fatty acid and cholesterol biosynthesis, Krebs cycle and gluconeogenesis. Fenofibrate changed significantly the expression of seven transcription factors. The estrogen receptor-related gamma gene was upregulated 2.36-fold and had a significant positive correlation with genes of lipid and lipoprotein metabolism and mitochondrial functions, indicating an important role of this orphan receptor in mediating the fenofibrate-induced activation of a specific subset of its target genes.National Institutes of Health (HL48739 and HL68216); European Union (LSHM-CT-2006-0376331, LSHG-CT-2006-037277); the Biomedical Research Foundation of the Academy of Athens; the Hellenic Cardiological Society; the John F Kostopoulos Foundatio

A Phantom-Node Method with Edge-Based Strain Smoothing for Linear Elastic Fracture Mechanics

This paper presents a novel numerical procedure based on the combination of an edge-based smoothed finite element (ES-FEM) with a phantom-node method for 2D linear elastic fracture mechanics. In the standard phantom-node method, the cracks are formulated by adding phantom nodes, and the cracked element is replaced by two new superimposed elements. This approach is quite simple to implement into existing explicit finite element programs. The shape functions associated with discontinuous elements are similar to those of the standard finite elements, which leads to certain simplification with implementing in the existing codes. The phantom-node method allows modeling discontinuities at an arbitrary location in the mesh. The ES-FEM model owns a close-to-exact stiffness that is much softer than lower-order finite element methods (FEM). Taking advantage of both the ES-FEM and the phantom-node method, we introduce an edge-based strain smoothing technique for the phantom-node method. Numerical results show that the proposed method achieves high accuracy compared with the extended finite element method (XFEM) and other reference solutions

Burden of injuries in Vietnam: emerging trends from a decade of economic achievement

BACKGROUND: Vietnam has been one of the fastest-growing world economies in the past decade. The burden of injuries can be affected by economic growth given the increased exposure to causes of injury as well as decreased morbidity and mortality of those that experience injury. It is of interest to evaluate the trends in injury burden that occurred alongside Vietnam's economic growth in the past decade. METHODS: Results from Global Burden of Disease 2017 were obtained and reviewed. Estimates of incidence, cause-specific mortality, years lived with disability, years of life lost, disability-adjusted life years were analysed and reported for 30 causes of injury in Vietnam from 2007 to 2017. RESULTS: Between 2007 and 2017, the age-standardised incidence rate of all injuries increased by 14.6% (11.5%-18.2%), while the age-standardised mortality rate decreased by 11.6% (3.0%-20.2%). Interpersonal violence experienced the largest increase in age-standardised incidence (28.3% (17.6%-40.1%)), while exposure to forces of nature had the largest decrease in age-standardised mortality (47.1% (37.9%-54.6%)). The five leading causes of injury in both 2007 and 2017 were road injuries, falls, exposure to mechanical forces, interpersonal violence and other unintentional injuries, all of which increased in incidence from 2007 to 2017. Injury burden varied markedly by age and sex. CONCLUSIONS: The rapid expansions of economic growth in Vietnam as well as improvements in the Sociodemographic Index have occurred alongside dynamic patterns in injury burden. These results should be used to develop and implement prevention and treatment programme

Knowledge transfer for scene-specific motion prediction

When given a single frame of the video, humans can not only interpret the content of the scene, but also they are able to forecast the near future. This ability is mostly driven by their rich prior knowledge about the visual world, both in terms of (i) the dynamics of moving agents, as well as (ii) the semantic of the scene. In this work we exploit the interplay between these two key elements to predict scene-specific motion patterns. First, we extract patch descriptors encoding the probability of moving to the adjacent patches, and the probability of being in that particular patch or changing behavior. Then, we introduce a Dynamic Bayesian Network which exploits this scene specific knowledge for trajectory prediction. Experimental results demonstrate that our method is able to accurately predict trajectories and transfer predictions to a novel scene characterized by similar elements