433 research outputs found
Short Hypoxia Does not Affect Plasma Leptin in Healthy Men under Euglycemic Clamp Conditions
Leptin is involved in the endocrine control of energy expenditure and body weight regulation. Previous studies emphasize a relationship between hypoxic states and leptin concentrations. The aim of this study was to investigate the effects of acute hypoxia on leptin concentrations in healthy subjects. We examined 14 healthy men. Hypoxic conditions were induced by decreasing oxygen saturation to 75% for 30 minutes. Plasma leptin concentrations were determined at baseline, after 3 hours of euglycemic clamping, during hypoxia, and repeatedly the following 2.5 hours thereafter. Our results show an increase of plasma leptin concentrations in the course of 6 hours of hyperinsulinemic-euglycemic clamping which may reflect diurnal rhythmicity. Notwithstanding, there was no difference between levels of leptin in the hypoxic and the normoxic condition (P = .2). Since we did not find any significant changes in leptin responses upon hypoxia, plasma leptin levels do not seem to be affected by short hypoxic episodes of moderate degree
Parallel programming environment for OpenMP
We present our effort to provide a comprehensive parallel programming environment for the OpenMP parallel directive language. This environment includes a parallel programming methodology for the OpenMP programming model and a set of tools ( Ursa Minor and InterPol) that support this methodology. Our toolset provides automated and interactive assistance to parallel programmers in time-consuming tasks of the proposed methodology. The features provided by our tools include performance and program structure visualization, interactive optimization, support for performance modeling, and performance advising for finding and correcting performance problems. The presented evaluation demonstrates that our environment offers significant support in general parallel tuning efforts and that the toolset facilitates many common tasks in OpenMP parallel programming in an efficient manner
Organizational Mortality of Small Firms: The Effects of Entrepreneurial Age and Human Capital
This paper addresses the issue of internal determination of organizational outcomes. It is argued that in small and simply structured organizations a considerable proportion of the variance in organizational activities and outcomes is associated with individuals. In particular, the paper uses human capital theory to derive hypotheses about individual determinants of organizational mortality. These hypotheses are tested with event-history data of firm registrations and de-registrations in a West German region. The hypotheses are corroborated by the data, but the effects may nonetheless be due to processes linking individual characteristics with organizational performance other than those suggested by the human capital approach
Measurement of the (90,91,92,93,94,96)Zr(n,gamma) and (139)La(n,gamma) cross sections at n_TOF
Open AccessNeutron capture cross sections of Zr and La isotopes have important implications in the field of nuclear astrophysics as well as in the nuclear technology. In particular the Zr isotopes play a key role for the determination of the neutron density in the He burning zone of the Red Giant star, while the (139)La is important to monitor the s-process abundances from Ba up to Ph. Zr is also largely used as structural materials of traditional and advanced nuclear reactors. The nuclear resonance parameters and the cross section of (90,91,92,93,94,96)Zr and (139)La have been measured at the n_TOF facility at CERN. Based on these data the capture resonance strength and the Maxwellian-averaged cross section were calculated
Measurements of high-energy neutron-induced fission of (nat)Pb and (209)Bi
This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial License 3.0, which permits unrestricted use, distribution, and reproduction in any noncommercial medium, provided the original work is properly citedThe CERN Neutron Time-Of-Flight (n_TOF) facility is well suited to measure low cross sections as those of neutron-induced fission in subactinides. The cross section ratios of (nat)Pb and (209)Bi relative to (235)U and (238)U were measured using PPAC detectors and a fragment coincidence method that allows us to identify the fission events. The present experiment provides first results for neutron-induced fission up to 1 GeV. Good agreement is found with previous experimental data below 200 MeV. The comparison with proton-induced fission indicates that the limiting regime where neutron-induced and proton-induced fission reach equal cross sections is close to 1 GeV
New measurement of neutron capture resonances of 209Bi
The neutron capture cross section of Bi209 has been measured at the CERN n
TOF facility by employing the pulse-height-weighting technique. Improvements
over previous measurements are mainly because of an optimized detection system,
which led to a practically negligible neutron sensitivity. Additional
experimental sources of systematic error, such as the electronic threshold in
the detectors, summing of gamma-rays, internal electron conversion, and the
isomeric state in bismuth, have been taken into account. Gamma-ray absorption
effects inside the sample have been corrected by employing a nonpolynomial
weighting function. Because Bi209 is the last stable isotope in the reaction
path of the stellar s-process, the Maxwellian averaged capture cross section is
important for the recycling of the reaction flow by alpha-decays. In the
relevant stellar range of thermal energies between kT=5 and 8 keV our new
capture rate is about 16% higher than the presently accepted value used for
nucleosynthesis calculations. At this low temperature an important part of the
heavy Pb-Bi isotopes are supposed to be synthesized by the s-process in the He
shells of low mass, thermally pulsing asymptotic giant branch stars. With the
improved set of cross sections we obtain an s-process fraction of 19(3)% of the
solar bismuth abundance, resulting in an r-process residual of 81(3)%. The
present (n,gamma) cross-section measurement is also of relevance for the design
of accelerator driven systems based on a liquid metal Pb/Bi spallation target.Comment: 10 pages, 5figures, recently published in Phys. Rev.
Measurement of the neutron capture cross section of the s-only isotope 204Pb from 1 eV to 440 keV
The neutron capture cross section of 204Pb has been measured at the CERN
n_TOF installation with high resolution in the energy range from 1 eV to 440
keV. An R-matrix analysis of the resolved resonance region, between 1 eV and
100 keV, was carried out using the SAMMY code. In the interval between 100 keV
and 440 keV we report the average capture cross section. The background in the
entire neutron energy range could be reliably determined from the measurement
of a 208Pb sample. Other systematic effects in this measurement could be
investigated and precisely corrected by means of detailed Monte Carlo
simulations. We obtain a Maxwellian average capture cross section for 204Pb at
kT=30 keV of 79(3) mb, in agreement with previous experiments. However our
cross section at kT=5 keV is about 35% larger than the values reported so far.
The implications of the new cross section for the s-process abundance
contributions in the Pb/Bi region are discussed.Comment: 8 pages, 3 figures, article submitted to Phys. Rev.
Resonance capture cross section of 207Pb
The radiative neutron capture cross section of 207Pb has been measured at the
CERN neutron time of flight installation n_TOF using the pulse height weighting
technique in the resolved energy region. The measurement has been performed
with an optimized setup of two C6D6 scintillation detectors, which allowed us
to reduce scattered neutron backgrounds down to a negligible level. Resonance
parameters and radiative kernels have been determined for 16 resonances by
means of an R-matrix analysis in the neutron energy range from 3 keV to 320
keV. Good agreement with previous measurements was found at low neutron
energies, whereas substantial discrepancies appear beyond 45 keV. With the
present results, we obtain an s-process contribution of 77(8)% to the solar
abundance of 207Pb. This corresponds to an r-process component of 23(8)%, which
is important for deriving the U/Th ages of metal poor halo stars.Comment: 7 pages, 3 figures, to be published in Phys. Rev.
Measurement of the radiative neutron capture cross section of 206Pb and its astrophysical implications
The (n, gamma) cross section of 206Pb has been measured at the CERN n_TOF
facility with high resolution in the energy range from 1 eV to 600 keV by using
two optimized C6D6 detectors. In the investigated energy interval about 130
resonances could be observed, from which 61 had enough statistics to be
reliably analyzed via the R-matrix analysis code SAMMY. Experimental
uncertainties were minimized, in particular with respect to (i) angular
distribution effects of the prompt capture gamma-rays, and to (ii) the
TOF-dependent background due to sample-scattered neutrons. Other background
components were addressed by background measurements with an enriched 208Pb
sample. The effect of the lower energy cutoff in the pulse height spectra of
the C6D6 detectors was carefully corrected via Monte Carlo simulations.
Compared to previous 206Pb values, the Maxwellian averaged capture cross
sections derived from these data are about 20% and 9% lower at thermal energies
of 5 keV and 30 keV, respectively. These new results have a direct impact on
the s-process abundance of 206Pb, which represents an important test for the
interpretation of the cosmic clock based on the decay of 238U.Comment: 11 pages, 8 figures, paper to be submitted to Phys. Rev.
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