Without the blanket of the land: agrarian change and biopolitics in post–Apartheid South Africa

This paper connects Marxist approaches to the agrarian political economy of South Africa with post-Marshallian and Foucauldian analyses of distributional regimes and late capitalist governmentality. Looking at South Africa’s stalled agrarian transition through the lens of biopolitics as well as class analysis can make visible otherwise disregarded connections between processes of agrarian change and broader contests about the terms of social and economic incorporation into the South African social and political order before, during and after Apartheid. This can bring a fresh sense of the broader political implications of the course of agrarian change in South Africa, and helps contextualise the enduring salience of land as a flashpoint within South Africa’s unresolved democratic transition

Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry

OBJECTIVES: The Digital Ulcers Outcome (DUO) Registry was designed to describe the clinical and antibody characteristics, disease course and outcomes of patients with digital ulcers associated with systemic sclerosis (SSc). METHODS: The DUO Registry is a European, prospective, multicentre, observational, registry of SSc patients with ongoing digital ulcer disease, irrespective of treatment regimen. Data collected included demographics, SSc duration, SSc subset, internal organ manifestations, autoantibodies, previous and ongoing interventions and complications related to digital ulcers. RESULTS: Up to 19 November 2010 a total of 2439 patients had enrolled into the registry. Most were classified as either limited cutaneous SSc (lcSSc; 52.2%) or diffuse cutaneous SSc (dcSSc; 36.9%). Digital ulcers developed earlier in patients with dcSSc compared with lcSSc. Almost all patients (95.7%) tested positive for antinuclear antibodies, 45.2% for anti-scleroderma-70 and 43.6% for anticentromere antibodies (ACA). The first digital ulcer in the anti-scleroderma-70-positive patient cohort occurred approximately 5 years earlier than the ACA-positive patient group. CONCLUSIONS: This study provides data from a large cohort of SSc patients with a history of digital ulcers. The early occurrence and high frequency of digital ulcer complications are especially seen in patients with dcSSc and/or anti-scleroderma-70 antibodies