The philosopher as artist: Ludwig Wittgenstein seen through Edoardo Paolozzi

In this article I argue that the strong fascination that Wittgenstein has had for artists cannot be explained primarily by the content of his work, and in particular not by his sporadic observation on aesthetics, but rather by stylistic features of his work formal aspects of his writing. Edoardo Paolozzi’s testimony shows that artists often had a feeling of acquaintance or familiarity with the philosopher, which I think is due to stylistic features of his work, such as the colloquial tone in which Wittgenstein shares his observation with the reader, but also the lack of long-winded arguments or explanations. In the concluding part I suggest that we can read Wittgenstein’s artworks of a specific kind: as philosophical works of art

How to measure patent thickets – a novel approach

The existing literature identifies patent thickets indirectly. In this paper we propose a novel measure based on patent citations which allows us to measure the density of patent thickets directly. We discuss the algorithm which generates the measure and present descriptive results validating it. Moreover, we identify technology areas which are particularly impacted by patent thickets

Hilbert Space Geometry of Random Matrix Eigenstates

The geometry of multiparameter families of quantum states is important in numerous contexts, including adiabatic or nonadiabatic quantum dynamics, quantum quenches, and the characterization of quantum critical points. Here, we discuss the Hilbert space geometry of eigenstates of parameter-dependent random matrix ensembles, deriving the full probability distribution of the quantum geometric tensor for the Gaussian unitary ensemble. Our analytical results give the exact joint distribution function of the Fubini-Study metric and the Berry curvature. We discuss relations to Levy stable distributions and compare our results to numerical simulations of random matrix ensembles as well as electrons in a random magnetic field

Rapid-prototyping of microscopic thermal landscapes in micro-focused Brillouin light scattering spectroscopy

Since temperature and its spatial and temporal variations affect a wide range of physical properties of material systems, they can be used to create reconfigurable spatial structures of various types in physical and biological objects. This paper presents an experimental optical setup for creating tunable two-dimensional temperature patterns on a micrometer scale. As an example of its practical application, we have produced temperature-induced magnetization landscapes in ferrimagnetic yttrium iron garnet films and investigated them using micro-focused Brillouin light scattering spectroscopy. It is shown that, due to the temperature dependence of the magnon spectrum, temperature changes can be visualized even for microscale thermal patterns.Comment: 5 pages, 4 figure

Confinement of Bose-Einstein magnon condensates in adjustable complex magnetization landscapes

Coherent wave states such as Bose-Einstein condensates (BECs), which spontaneously form in an overpopulated magnon gas even at room temperature, have considerable potential for wave-based computing and information processing at microwave frequencies. The ability to control the transport properties of magnon BECs plays an essential role for their practical use. Here, we demonstrate spatio-temporal control of the BEC density distribution through the excitation of magnon supercurrents in an inhomogeneously magnetized yttrium iron garnet film. The BEC is created by microwave parametric pumping and probed by Brillouin light scattering spectroscopy. The desired magnetization profile is prepared by heating the film with optical patterns projected onto its surface using a phase-based wavefront modulation technique. Specifically, we observe a pronounced spatially localized magnon accumulation caused by magnon supercurrents flowing toward each other originating in two heated regions. This accumulation effect increases the BEC lifetime due to the constant influx of condensed magnons into the confinement region. The shown approach to manipulate coherent waves provides an opportunity to extend the lifetime of freely evolving magnon BECs, create dynamic magnon textures, and study the interaction of magnon condensates formed in different regions of the sample.Comment: 8 pages, 4 figure

Characterization of the Ca2+-gated and voltage-dependent k+-channel slo-1 of nematodes and its interaction with emodepside

The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-spectrum nematicidal drugs which are able to eliminate nematodes resistant to other anthelmintics. The mode of action of cyclooctadepsipeptides is only partially understood, but involves the latrophilin Lat-1 receptor and the voltage- and calcium-activated potassium channel Slo-1. Genetic evidence suggests that emodepside exerts its anthelmintic activity predominantly through Slo-1. Indeed, slo-1 deficient Caenorhabditis elegans strains are completely emodepside resistant. However, direct effects of emodepside on Slo-1 have not been reported and these channels have only been characterized for C. elegans and related Strongylida. Molecular and bioinformatic analyses identified full-length Slo-1 cDNAs of Ascaris suum, Parascaris equorum, Toxocara canis, Dirofilaria immitis, Brugia malayi, Onchocerca gutturosa and Strongyloides ratti. Two paralogs were identified in the trichocephalids Trichuris muris, Trichuris suis and Trichinella spiralis. Several splice variants encoding truncated channels were identified in Trichuris spp. Slo-1 channels of trichocephalids form a monophyletic group, showing that duplication occurred after the divergence of Enoplea and Chromadorea. To explore the function of a representative protein, C. elegans Slo-1a was expressed in Xenopus laevis oocytes and studied in electrophysiological (voltage-clamp) experiments. Incubation of oocytes with 1-10 µM emodepside caused significantly increased currents over a wide range of step potentials in the absence of experimentally increased intracellular Ca2+, suggesting that emodepside directly opens C. elegans Slo-1a. Emodepside wash-out did not reverse the effect and the Slo-1 inhibitor verruculogen was only effective when applied before, but not after, emodepside. The identification of several splice variants and paralogs in some parasitic nematodes suggests that there are substantial differences in channel properties among species. Most importantly, this study showed for the first time that emodepside directly opens a Slo-1 channel, significantly improving the understanding of the mode of action of this drug class

Mapping of the range of operational conditions for Cu-, Fe-, and Ni-based oxygen carriers in chemical-looping combustion

Available online September 14, 2006.- El pdf del artículo es la versión post-printChemical-looping combustion (CLC) is a two-step combustion process that produces a pure CO2 stream, ready for compression and sequestration. A CLC system is composed by two reactors, an air and a fuel reactor, and an oxygen carrier (OC) circulating between the reactors, which transfers the oxygen necessary for the fuel combustion from the air to the fuel. This system can be designed similar to a circulating fluidised bed, but with the addition of a bubbling fluidised bed on the return side. A mapping of the range of operational conditions, design values, and OC characteristics is presented for the most usual metal oxides (CuO, Fe2O3, and NiO) and different fuel gases (CH4, H2, and CO). The pressure operation of a CLC system is also considered. Moreover, a comparison of the possible use of three high reactive OCs (Cu10Al-I, Fe45Al-FG, Ni40Al-FG) previously characterised is carried out. It was found that the circulation rates and the solids inventories are linked, and the possible operating conditions are closely dependent on the reactivity of the OCs. The operational limits of the solids circulation rates, given by the mass and heat balances in the system, were defined for the different type of OCs. Moreover, a plot to calculate the solids inventories in a CLC system, valid for any type of OC and fuel gas, is proposed. The minimum solids inventories depended on the fuel gas used, and followed the order CH4 > CO > H2. Values of minimum solids inventories in a range from 40 to 133 kg / MWf were found for the OCs used in this work, excepting for the reaction of Fe45Al-FG with CH4, which needs a higher amount of solids because of its low reactivity. From the economic analysis carried out it was found the cost of the OC particles does not represent any limitation to the development of the CLC technology. © 2006 Elsevier Ltd. All rights reserved.This work was carried out with financial support from the European Coal and Steel Community (Project 7220-PR/125), and the Spanish Ministry of Education and Science (Project CTQ2004- 04034).Peer Reviewe

The Epsilon Calculus and Herbrand Complexity

Hilbert's epsilon-calculus is based on an extension of the language of predicate logic by a term-forming operator $\epsilon_{x}$. Two fundamental results about the epsilon-calculus, the first and second epsilon theorem, play a role similar to that which the cut-elimination theorem plays in sequent calculus. In particular, Herbrand's Theorem is a consequence of the epsilon theorems. The paper investigates the epsilon theorems and the complexity of the elimination procedure underlying their proof, as well as the length of Herbrand disjunctions of existential theorems obtained by this elimination procedure.Comment: 23 p

Observation of discrete time-crystalline order in a disordered dipolar many-body system

Understanding quantum dynamics away from equilibrium is an outstanding challenge in the modern physical sciences. It is well known that out-of-equilibrium systems can display a rich array of phenomena, ranging from self-organized synchronization to dynamical phase transitions. More recently, advances in the controlled manipulation of isolated many-body systems have enabled detailed studies of non-equilibrium phases in strongly interacting quantum matter. As a particularly striking example, the interplay of periodic driving, disorder, and strong interactions has recently been predicted to result in exotic "time-crystalline" phases, which spontaneously break the discrete time-translation symmetry of the underlying drive. Here, we report the experimental observation of such discrete time-crystalline order in a driven, disordered ensemble of $\sim 10^6$ dipolar spin impurities in diamond at room-temperature. We observe long-lived temporal correlations at integer multiples of the fundamental driving period, experimentally identify the phase boundary and find that the temporal order is protected by strong interactions; this order is remarkably stable against perturbations, even in the presence of slow thermalization. Our work opens the door to exploring dynamical phases of matter and controlling interacting, disordered many-body systems.Comment: 6 + 3 pages, 4 figure