Life after eruption, II : the eclipsing old nova V728 Scorpii

The old nova V728 Sco has been recently recovered via photometric and spectroscopic observations, 150 yr after the nova eruption. The spectral properties pointed to a high-inclination system with a comparatively low mass-transfer rate. In this paper, we show that the object is an eclipsing system with an orbital period of 3.32 h. It has enhanced long-term variability that can be interpreted as `stunted' dwarf-nova-type outbursts. Using the ingress and egress times of the eclipsed components we calculate the radius of the central object. The latter turns out to be significantly larger than a white dwarf and we identify it with a hot inner disc. The implications for models on the behaviour of post-novae are discussed

The Role of Governance in Tourism Planning

This research tests Beaumont and Dredge’s tourism application of governance structure theory using recent tourism planning efforts in the community of Sitka, Alaska. In less than two years, the community of Sitka undertook two separate tourism-planning processes in response to a major tourism event (need for cruise dock to accommodate large cruise ships). The first plan followed a participant-led governance structure, the second plan a council-led governance structure. The participant-led governance structure produced a plan through a collaborative process that empowered citizen participants and sought to limit growth, while the council-led structure produced a more pro-growth plan and downplayed citizen concern for maintaining quality of life. Through this research, tourism governance structures are critically analyzed with a clearer understanding of advantages and disadvantages of planning processes under differing governance structures

Coping with Tourism: The Case of Sitka, Alaska

In this case study, resident coping strategies for dealing with the proposed development of a cruise style dock in the community of Sitka, AK are examined. Tourism literature is surprisingly devoid of research examining coping behaviors; therefore a definition developed by Folkman and Lazarus (1980) is utilized. This research shows that the tourism planning process is an example of coping behavior, although certain elements of community dynamics prevented coping strategies from being particularly successful

Characterisation of Bombyx mori odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components

In many insect species, odorant-binding proteins (OBPs) are thought to be responsible for the transport of pheromones and other semiochemicals across the sensillum lymph to the olfactory receptors (ORs) within the antennal sensilla. In the silkworm Bombyx mori, the OBPs are subdivided into three main subfamilies; pheromone-binding proteins (PBPs), general odorant-binding proteins (GOBPs) and antennal-binding proteins (ABPs). We used the MotifSearch algorithm to search for genes encoding putative OBPs in B. mori and found 13, many fewer than are found in the genomes of fruit flies and mosquitoes. The 13 genes include seven new ABP-like OBPs as well as the previously identified PBPs (three), GOBPs (two) and ABPx. Quantitative examination of transcript levels showed that BmorPBP1, BmorGOBP1, BmorGOBP2 and BmorABPx are expressed at very high levels in the antennae and so could be involved in olfaction. A new two-phase binding assay, along with other established assays, showed that BmorPBP1, BmorPBP2, BmorGOBP2 and BmorABPx all bind to the B. mori sex pheromone component (10E,12Z)-hexadecadien-1-ol (bombykol). BmorPBP1, BmorPBP2 and BmorABPx also bind the pheromone component (10E,12Z)-hexadecadienal (bombykal) equally well, whereas BmorGOBP2 can discriminate between bombykol and bombykal. X-ray structures show that when bombykol is bound to BmorGOBP2 it adopts a different conformation from that found when it binds to BmorPBP1. Binding to BmorGOBP2 involves hydrogen bonding to Arg110 rather than to Ser56 as found for BmorPBP1

Möglichkeitsräume an Hochschulen post Corona experimentell gestalten

Dieser Beitrag stellt Ergebnisse einer qualitativen Studie vor, die unter Studierenden, Lehrenden und Hochschulleitungen im Frühjahr 2021 an elf Hochschulen fächerübergreifend durchgeführt wurde. Zunächst werden anhand der Begriffe Kontingenz und Möglichkeitsraum die Herausforderungen der Gestaltung der zukünftigen Hochschullehre dargestellt. Die Methode des Experimentierens hat in den Corona-Semestern eine entscheidende Rolle gespielt und kann zusammen mit einer inkrementellen Arbeitsweise auch zukünftig sinnvoll sein. In diesem Artikel werden Dimensionen im Möglichkeitsraum der Hochschullehre erörtert, welche als Experimentierfelder gestaltet werden können

Wissenschaftliche Weiterbildung als Format für Wissenstransfer

Das Aufgabenfeld von Hochschulen umfasst nicht nur Lehre und Forschung, sie sollen auch zur Problemlösung gesellschaftlicher Herausforderungen beitragen. Wissenschaftliche Weiterbildung wird dabei als Format zum Wissenstransfer zwischen Hochschule und Gesellschaft angewendet. Nun stellt sich die Frage, wie dieses Transferformat „wissenschaftliche Weiterbildung“ gestaltet werden kann, damit es gelingt? Der Beitrag behandelt diese Fragestellung, indem er zunächst die Faktoren aufzeigt, die einen Wissenstransfer grundsätzlich beeinflussen. Damit die Einflussfaktoren zu Erfolgsfaktoren des Transferformats der wissenschaftlichen Weiterbildung werden können, erfolgt darauf die Adaption bereits bekannter Gelingensbedingungen aus der transformativen Forschung auf die wissenschaftliche Weiterbildung. Aus der Zusammenführung der Einflussfaktoren und der Gelingensbedingungen ergeben sich Empfehlungen für das Transferformat der wissenschaftlichen Weiterbildung

Wissenschaftliche Weiterbildung als Format für Wissenstransfer

Das Aufgabenfeld von Hochschulen umfasst nicht nur Lehre und Forschung, sie sollen auch zur Problemlösung gesellschaftlicher Herausforderungen beitragen. Wissenschaftliche Weiterbildung wird dabei als Format zum Wissenstransfer zwischen Hochschule und Gesellschaft angewendet. Nun stellt sich die Frage, wie dieses Transferformat „wissenschaftliche Weiterbildung“ gestaltet werden kann, damit es gelingt? Der Beitrag behandelt diese Fragestellung, indem er zunächst die Faktoren aufzeigt, die einen Wissenstransfer grundsätzlich beeinflussen. Damit die Einflussfaktoren zu Erfolgsfaktoren des Transferformats der wissenschaftlichen Weiterbildung werden können, erfolgt darauf die Adaption bereits bekannter Gelingensbedingungen aus der transformativen Forschung auf die wissenschaftliche Weiterbildung. Aus der Zusammenführung der Einflussfaktoren und der Gelingensbedingungen ergeben sich Empfehlungen für das Transferformat der wissenschaftlichen Weiterbildung. (DIPF/Orig.

Inpatient signs and symptoms and factors associated with death in children aged 5 years and younger admitted to two Ebola management centres in Sierra Leone, 2014: a retrospective cohort study

Background Médecins Sans Frontières (MSF) opened Ebola management centres (EMCs) in Sierra Leone in Kailahun in June, 2014, and Bo in September, 2014. Case fatality in the west African Ebola virus disease epidemic has been highest in children younger than 5 years. Clinical data on outcomes can provide important evidence to guide future management. However, such data on children are scarce and disaggregated clinical data across all ages in this epidemic have focussed on symptoms reported on arrival at treatment facilities, rather than symptoms and signs observed during admission. We aimed to describe the clinical characteristics of children aged 5 years and younger admitted to the MSF EMCs in Bo and Kailahun, and any associations between these characteristics and mortality. Methods In a retrospective cohort study, we included data from children aged 5 years and younger with laboratoryconfi rmed Ebola virus disease admitted to EMCs between June and December, 2014. We described epidemiological, demographic, and clinical characteristics and viral load (measured using Ebola virus cycle thresholds [Ct]), and assessed their association with death using Cox regression modelling. Findings We included 91 children in analysis; 52 died (57·1%). Case fatality was higher in children aged less than 2 years (76·5% [26/34]) than those aged 2–5 years (45·6% [26/57]; adjusted HR 3·5 [95% CI 1·5–8·5]) and in those with high (Ct<25) versus low (Ct≥25) viral load (81·8% [18/22] vs 45·9% [28/61], respectively; adjusted HR 9·2 [95% CI 3·8–22·5]). Symptoms observed during admission included: weakness 74·7% (68); fever 70·8% (63/89); distress 63·7% (58); loss of appetite 60·4% (55); diarrhoea 59·3% (54); and cough 52·7% (48). At admission, 25% (19/76) of children were afebrile. Signs signifi cantly associated with death were fever, vomiting, and diarrhoea. Hiccups, bleeding, and confusion were observed only in children who died. Interpretation This description of the clinical features of Ebola virus disease over the duration of illness in children aged 5 years and younger shows symptoms associated with death and a high prevalence of distress, with implications for clinical management. Collection and analysis of age-specifi c data on Ebola is very important to ensure that the specifi c vulnerabilities of children are addressed