107 research outputs found
A 10-year update to the principles for clinical trial data sharing by pharmaceutical companies: perspectives based on a decade of literature and policies
The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing
Ionospheric response modeling under eclipse conditions: Evaluation of 14 December 2020, total solar eclipse prediction over the South American sector
In this work, we evaluate the SUPIM-INPE model prediction of the 14 December 2020, total solar eclipse over the South American continent. We compare the predictions with data from multiple instruments for monitoring the ionosphere and with different obscuration percentages (i.e., Jicamarca, 12.0°S, 76.8°W, 17%; TucumĂĄn 26.9°S, 65.4° W, 49%; ChillĂĄn 36.6°S, 72.0°W; and BahĂa Blanca, 38.7°S, 62.3°W, reach 95% obscuration) due to the eclipse. The analysis is done under total eclipse conditions and non-total eclipse conditions. Results obtained suggest that the model was able to reproduce with high accuracy both the daily variation and the eclipse impacts of E and F1 layers in the majority of the stations evaluated (except in Jicamarca station). The comparison at the F2 layer indicates small differences (<7.8%) between the predictions and observations at all stations during the eclipse periods. Additionally, statistical metrics reinforce the conclusion of a good performance of the model. Predicted and calibrated Total Electron Content (TEC, using 3 different techniques) are also compared. Results show that, although none of the selected TEC calibration methods have a good agreement with the SUPIM-INPE prediction, they exhibit similar trends in most of the cases. We also analyze data from the Jicamarca Incoherent Scatter Radar (ISR), and Swarm-A and GOLD missions. The electron temperature changes observed in ISR and Swarm-A are underestimated by the prediction. Also, important changes in the O/N2 ratio due to the eclipse, have been observed with GOLD mission data. Thus, future versions of the SUPIM-INPE model for eclipse conditions should consider effects on thermospheric winds and changes in composition, specifically in the O/N2 ratio
IRMM-1000a and IRMM-1000b uranium reference materials certified for the production date. Part I: methodology, preparation and target characteristics
The GEOTRACES Intermediate Data Product 2014
The GEOTRACES Intermediate Data Product 2014 (IDP2014) is the first publicly available data product of the international GEOTRACES programme, and contains data measured and quality controlled before the end of 2013. It consists of two parts: (1) a compilation of digital data for more than 200 trace elements and isotopes (TEIs) as well as classical hydrographic parameters, and (2) the eGEOTRACES Electronic Atlas providing a strongly inter-linked on-line atlas including more than 300 section plots and 90 animated 3D scenes. The IDP2014 covers the Atlantic, Arctic, and Indian oceans, exhibiting highest data density in the Atlantic. The TEI data in the IDP2014 are quality controlled by careful assessment of intercalibration results and multi-laboratory data comparisons at cross-over stations. The digital data are provided in several formats, including ASCII spreadsheet, Excel spreadsheet, netCDF, and Ocean Data View collection. In addition to the actual data values the IDP2014 also contains data quality flags and 1-? data error values where available. Quality flags and error values are useful for data filtering. Metadata about data originators, analytical methods and original publications related to the data are linked to the data in an easily accessible way. The eGEOTRACES Electronic Atlas is the visual representation of the IDP2014 data providing section plots and a new kind of animated 3D scenes. The basin-wide 3D scenes allow for viewing of data from many cruises at the same time, thereby providing quick overviews of large-scale tracer distributions. In addition, the 3D scenes provide geographical and bathymetric context that is crucial for the interpretation and assessment of observed tracer plumes, as well as for making inferences about controlling processes
The reference site collaborative network of the european innovation partnership on active and healthy ageing
Seventy four Reference Sites of the European Innovation
Partnership on Active and Healthy Ageing (EIP on AHA)
have been recognised by the European Commission in
2016 for their commitment to excellence in investing and
scaling up innovative solutions for active and healthy
ageing. The Reference Site Collaborative Network
(RSCN) brings together the EIP on AHA Reference Sites
awarded by the European Commission, and Candidate
Reference Sites into a single forum. The overarching goals
are to promote cooperation, share and transfer good
practice and solutions in the development and scaling up
of health and care strategies, policies and service delivery
models, while at the same time supporting the action
groups in their work. The RSCN aspires to be recognized
by the EU Commission as the principal forum and
authority representing all EIP on AHA Reference Sites.
The RSCN will contribute to achieve the goals of the EIP
on AHA by improving health and care outcomes for
citizens across Europe, and the development of sustainable
economic growth and the creation of jobs
Compensatio lucri cum damno: The Decisions of the Sezioni Unite of Italian Court of Cassation
Before examining the new position that the Italian Supreme Court has assumed with the recent decisions of the United Sections on compensatio lucri cum damno, this article analyses the origins of the doctrine, its foundations and the traditional sphere of operation in the Italian law system. Finally, some concluding remarks will be formulated
Four Judgments of the Sezioni Unite of the Italian Court of Cassation on the compensatio lucri cum damno
In certain cases, an unlawful act or a breach of contract, apart from disadvantageous consequences, could confer economic benefit on the injured party. For determining the compensation, in such cases it is necessary to take account not only of harms suffered by the victim, but also the advantages that he or she has possibly achieved. Generally, the law scholars expressed that need with the elaboration of the \u2018compensatio lucri cum damno\u2019 doctrine (from now also \u2018c.l.c.d\u2019.).
On 22 May 2018, in order to clarify a contrast existing among the different Sections, the Sezioni Unite of the Italian Court of Cassation provided a meticulous discussion of the foundations and the rules of this doctrine
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