18 research outputs found
Gender Differences in Patients Candidates for Bariatric Surgery: Anxiety, Depression and Causal Attributions
Objetivo. Analizar la relación entre las variables psicológicas tipo de
atribución, sintomatología ansiosa y sintomatología depresiva en
función del género en una muestra de pacientes con obesidad mórbida
candidatos a cirugía bariátrica.
Material y Métodos. Estudio observacional, transversal y unicéntrico.
Se seleccionaron 259 pacientes candidatos a cirugía bariátrica del
Hospital Universitario Virgen del Rocío, Sevilla. Se utilizaron plantillas
para la recogida de datos sociodemográficos y clínicos, así como el
instrumento validado Escala de Ansiedad y Depresión Hospitalaria.
Resultados. En su mayoría, los pacientes realizaron atribuciones
controlables, aunque las mujeres presentaron una mayor proporción de
atribuciones incontrolables. En lo que respecta a la sintomatología
ansiosa y depresiva, se encontró que los pacientes no aptos para la
cirugía bariátrica presentaron mayores niveles de sintomatología
ansiosa y depresiva. Además, apareció una tendencia a que mayores
niveles de sintomatología ansiosa y depresiva estuvieran asociados a atribuciones de tipo controlable, lo que resulta
controvertido atendiendo a la literatura disponible.
Conclusiones. Este estudio muestra la importancia de continuar investigando acerca de distintas variables psicológicas para
ajustar los tratamientos preoperatorios a las características de los pacientes, así como de realizar investigaciones que tengan
en cuenta también medidas postoperatorias que permitan encontrar variables predictoras del éxito de las intervenciones.Objective. To analyze the relationship between the psychological
variables type of attribution, anxiety and depressive symptoms according
to gender in a sample of patients with morbid obesity who are candidates
for bariatric surgery.
Material and methods. Observational, cross-sectional and single-center
study. 259 patients who were candidates for bariatric surgery were
selected from the Virgen del Rocío University Hospital, Seville. Templates
were used to collect sociodemographic and clinical data, as well as the
validated Hospital Anxiety and Depression Scale instrument.
Results. Most of the patients had controllable attributions, although
women had a higher proportion of uncontrollable attributions. Regarding
anxiety and depressive symptoms, it was found that patients ineligible for
bariatric surgery presented higher levels of anxiety and depression. In
addition, there was a tendency for higher levels of anxiety and depressive
symptoms to be associated with controllable attributions, which is
controversial based on the available literature
Air-sea CO2 fluxes in the Atlantic as measured during the FICARAM cruises
A total of fourteen hydrographic cruises spanning from 2000 to 2008 were conducted
during the spring and autumn seasons between Spain and the Southern Ocean, under
the framework of the Spanish research project FICARAM. The performed underway measurements are processed and analysed to describe the meridional air-sea CO2
fluxes (F CO2) along the Atlantic Ocean. The data was organised into different biogeochemical
oceanographic provinces, according mainly to the thermohaline characteristics.
The obtained spatial and temporal distributions of F CO2 follow the generally expected
patterns and annual trends. The Subtropical regions in both hemispheres alternated the CO2 source and sink nature from autumn to spring, respectively. On the other
hand, Tropical waters and the Patagonian Sea clearly behaved as sinks of atmospheric
CO2 like the waters of the Drake Passage during autumn. The obtained results during
the cruises also revealed significant long-term trends, such as the warming of equatorial
waters (0.11±0.03 Cyr−1) and the decrease of surface salinity (−0.16±0.01 yr−1)
in tropical waters caused by the influence of the Amazon River plume. This reduction
in surface salinity appears to have a direct influence over the CO2 storage rates, fostering
the uptake capacity of atmospheric CO2 (−0.09±0.03 molm−2 yr−1). An analysis
of the biogeochemical forcing on the CO2 fugacity (fCO2) variability performed from
an empirical algorithm highlighted the major role of the Amazon River input in the tropical North Atlantic fluxes. In addition, it has provided a quantitative measure of the
importance of the thermodynamic control of F CO2 at temperate latitudes
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
La hepatopatía crónica en el trasplantado renal: influencia sobre la evolución clínica y estudio de la histología hepática
Tesis doctoral inédita. Universidad Autónoma de Madrid, Facultad de Medicina,Departamento de Medicina. Fecha de lectura: 17 de Diciembre de 199
Physical oceanography, CFC-12, SF6, pH, and alkalinity measured on water bottle samples during cruise SUBPOLAR08 with RV Thalassa
Temperature, salinity, oxygen data, anthropogenic tracers, pH and alkalinity measured on the RV Thalassa Cruise SUBPOLAR08 St. John's - Brest 08/25 - 09/15/2008
Chief Scientist: Dagmar Kieke
Region: Subpolar North Atlanti
Dyslipemia in Our Society: Is There Anything Beyond Lipid Profile?
Original[ES] Dos aspectos relevantes de la medicina laboral son estudiar la salud del individuo en su ámbito de
trabajo y promover entornos laborales saludables. Actualmente, los factores de riesgo cardiovascular siguen liderando la morbi-mortalidad en nuestra sociedad. El entorno laboral es la oportunidad de conocer la situación real e iniciar estrategias de prevención precoz. Uno de los factores más prevalentes son las alteraciones de los lípidos, siendo el colesterol LDL el que define el riesgo del paciente, pero sabemos que no identifica a todos los pacientes en riesgo de padecer un evento, persistiendo un riesgo residual.
Determinar el número y tamaño de partículas de lipoproteínas mediante resonancia magnética nuclear,
aporta valor añadido en la identificación de pacientes con riesgo lipídico. Esta revisión presenta una
actualización de la situación del riesgo lipídico y muestra las características de un nuevo método para la
caracterización de las lipoproteínas basada en espectroscopia de RMN de difusión 2D.
[EN] Two relevant aspects of occupational medicine are studying the health of the individual in their
occupational environment and promoting healthy occupational environments.
Currently, cardiovascular risk factors continue to lead morbidity and mortality in our society. The
occupational environment is the opportunity to know the real situation and initiate early prevention strategies.
One of the most prevalent factors are the alterations of the lipids, being the LDL cholesterol (low-density
lipoprotein) the one that defines the risk of the patient, but we know that it does not identify all patients at
risk of suffering an event, persisting a residual risk.
Determining the number and size of lipoprotein particles by nuclear magnetic resonance provides
added value in the identification of patients with lipid risk. This review presents an update of the status of
lipid risk and shows the characteristics of a new method for the characterization of lipoproteins based on
2D diffusion NMR spectroscopy.N
Glomerular binding and contractile response to angiotensin II in rats with chronic experimental cirrhosis of the liver
La dislipemia en nuestra sociedad: ¿hay algo más allá del perfil lipídico?
Resumen Dos aspectos relevantes de la medicina laboral son estudiar la salud del individuo en su ámbito de trabajo y promover entornos laborales saludables. Actualmente, los factores de riesgo cardiovascular siguen liderando la morbi-mortalidad en nuestra sociedad. El entorno laboral es la oportunidad de conocer la situación real e iniciar estrategias de prevención precoz. Uno de los factores más prevalentes son las alteraciones de los lípidos, siendo el colesterol LDL el que define el riesgo del paciente, pero sabemos que no identifica a todos los pacientes en riesgo de padecer un evento, persistiendo un riesgo residual. Determinar el número y tamaño de partículas de lipoproteínas mediante resonancia magnética nuclear, aporta valor añadido en la identificación de pacientes con riesgo lipídico. Esta revisión presenta una actualización de la situación del riesgo lipídico y muestra las características de un nuevo método para la caracterización de las lipoproteínas basada en espectroscopia de RMN de difusión 2D
La cultura oral en Acebo y sierra de Gata
En el documento no aparece la fecha de publicaciónTras hacer un análisis de las geografía, la historia y otros aspectos culturales de Acebo (Cáceres) y de la zona de la sierra de Gata (Cáceres) se presentan una serie de tradiciones de la zona (juegos populares, refranes, poesías, canciones, etc.) que se han trasmitido de generación en generación y que pretenden ser un material que permita a los alumnos describir, conocer y valorar su propia cultura y tradiciones.ExtremaduraCPR de Navalmoral de la Mata (Cáceres); Avda. San Isidro, 10; Apdo. 221; 10300 Navalmoral de la Mata (Cáceres); +34927016720; +34927016721; [email protected]
Meridional overturning circulation conveys fast acidification to the deep Atlantic Ocean
Since the Industrial Revolution, the North Atlantic Ocean has been accumulating anthropogenic carbon dioxide (CO2) and experiencing ocean acidification, that is, an increase in the concentration of hydrogen ions (a reduction in pH) and a reduction in the concentration of carbonate ions. The latter causes the 'aragonite saturation horizon' - below which waters are undersaturated with respect to a particular calcium carbonate, aragonite - to move to shallower depths (to shoal), exposing corals to corrosive waters. Here we use a database analysis to show that the present rate of supply of acidified waters to the deep Atlantic could cause the aragonite saturation horizon to shoal by 1,000-1,700 metres in the subpolar North Atlantic within the next three decades. We find that, during 1991-2016, a decrease in the concentration of carbonate ions in the Irminger Sea caused the aragonite saturation horizon to shoal by about 10-15 metres per year, and the volume of aragonite-saturated waters to reduce concomitantly. Our determination of the transport of the excess of carbonate over aragonite saturation ((xc)[CO3(2-)]) - an indicator of the availability of aragonite to organisms - by the Atlantic meridional overturning circulation shows that the present-day transport of carbonate ions towards the deep ocean is about 44 per cent lower than it was in preindustrial times. We infer that a doubling of atmospheric anthropogenic CO2 levels - which could occur within three decades according to a 'business-as-usual scenario' for climate change - could reduce the transport of (xc)[CO3(2-)] by 64-79 per cent of that in preindustrial times, which could severely endanger cold-water coral habitats. The Atlantic meridional overturning circulation would also export this acidified deep water southwards, spreading corrosive waters to the world ocean