465 research outputs found
Os ODS nos relatórios de sustentabilidade em empresas do Equador, Colômbia e Chile
The Sustainable Development Goals (SDGs) linked to the 2030 Agenda have been widely accepted by public and private companies, with many choosing to incorporate them within the framework of their social responsibility initiatives. This research article aims to find out how the SDGs are reflected in corporate sustainability reports and in which business activities they stand out the most. To this end, using a sequential explanatory methodology, the authors analyzed 12 sustainability reports issued in 2021 by large companies in Colombia, Chile, and Ecuador to verify their alignment with the SDGs. The reports showed evidence of a diverse range of programs associated with at least three SDGs, thus highlighting the importance of fulfilling not only the needs based on each company’s field of expertise but also those of its audiences and the community in general. The most prevalent SDGs were “decent work and economic growth” (SDG 8) and “gender equality” (SDG 5), followed by “responsible consumption and production” (SDG 12). This paper contributes to a growing interest among academia in the research on sustainability communication evidenced in annual reports.Iniciativas globales como los Objetivos de Desarrollo Sostenible, ODS, impulsados por las Naciones Unidas, han sido fuertemente promovidos gracias a la acogida que las empresas públicas y privadas han dado en el marco de sus acciones de responsabilidad social; sin embargo se requiere conocer de qué manera los ODS se reflejan en los reportes de sostenibilidad y cuáles son los de mayor presencia. Se realizó un análisis de contenido a los reportes de sostenibilidad del año 2021 de doce grandes empresas de Colombia, Chile y Ecuador para constatar su relación con los ODS. Los hallazgos mostraron que, a pesar de la pandemia, las empresas mantuvieron sus programas de responsabilidad social conscientes del valor de las comunicaciones. La creación de trabajo decente y el crecimiento económico (ODS 8) así como la igualdad de género (ODS 5) son los ODS más frecuentes, seguidos de la producción y el consumo responsable (ODS 12). Los informes también mostraron que las empresas han implementado una gama de programas con más de tres ODS, lo que destaca la importancia de no solo satisfacer las necesidades del campo de especialización de cada empresa, sino también las necesidades de sus públicos y comunidad en general.Iniciativas globais como os Objetivos de Desenvolvimento Sustentável, ODS, promovidos pelas Nações Unidas, têm sido fortemente promovidas graças à acolhida que empresas públicas e privadas têm dado no âmbito de suas ações de responsabilidade social; porém, é preciso saber como os ODS se refletem nos relatórios de sustentabilidade e quais têm maior presença. Foi realizada uma análise de conteúdo nos relatórios de sustentabilidade 2021 de doze grandes empresas da Colômbia, Chile e Equador para verificar sua relação com os ODS. As descobertas mostraram que, apesar da pandemia, as empresas mantiveram seus programas de responsabilidade social conscientes do valor das comunicações. A criação de trabalho decente e crescimento econômico (ODS 8), bem como a igualdade de gênero (ODS 5) são os ODS mais frequentes, seguidos pela produção e consumo responsáveis (ODS 12). Os relatórios também mostraram que as empresas implementaram uma série de programas com mais de três ODS, destacando a importância de atender não apenas às necessidades da área de atuação de cada empresa, mas também às necessidades de seus públicos e da comunidade em geral
Productividad y calidad de los cuerpos fructíferos de los hongos comestibles Pleurotus pulmonarius RN2 y P. djamor RN81 y RN82 cultivados sobre sustratos lignocelulósicos
Parámetros tales como eficiencia biológica (EB), tasa de productividad (TP), tamaño de los cuerpos
fructíferos, grasa, fibra, carbohidratos totales, valor de energía y proteínas totales, fueron determinados y
analizados para hongos comestibles de la cepa importada Pleurotus pulmonarius RN2 y dos cepas nativas
de Panamá P.djamor RN81 y RN82, cultivadas sobre paja de arroz (Oriza sativa L), rastrojo y tuza de maíz
(Zea maíz L.). El objetivo fue establecer si existían diferencias significativas en estos parámetros, por efecto
de la cepa, el tipo de sustrato o su interacción. Más del 50% de los hongos cosechados presentó un tamaño
entre 5 y10 cm. Se destaca un alto contenido de proteína para el hongo P. djamor RN82 crecido sobre tuza
de maíz (43.07%) y una alta eficiencia biológica para P. pulmonarius RN2 (75.65%). Se obtuvo diferencias
significativas para la eficiencia biológica, proteínas, carbohidratos y fibra por efecto de la interacción cepa
sustrato
What’s in a gene? The outstanding diversity of MAPT
Tau protein is a microtubule-associated protein encoded by the MAPT gene that carries out a myriad of physiological functions and has been linked to certain pathologies collectively termed tauopathies, including Alzheimer’s disease, frontotemporal dementia, Huntington’s disease, progressive supranuclear palsy, etc. Alternative splicing is a physiological process by which cells generate several transcripts from one single gene and may in turn give rise to different proteins from the same gene. MAPT transcripts have been proven to be subjected to alternative splicing, generating six main isoforms in the central nervous system. Research throughout the years has demonstrated that the splicing landscape of the MAPT gene is far more complex than that, including at least exon skipping events, the use of 3′ and 5′ alternative splice sites and, as has been recently discovered, also intron retention. In addition, MAPT alternative splicing has been showed to be regulated spatially and developmentally, further evidencing the complexity of the gene’s splicing regulation. It is unclear what would drive the need for the existence of so many isoforms encoded by the same gene, but a wide range of functions have been ascribed to these Tau isoforms, both in physiology and pathology. In this review we offer a comprehensive up-to-date exploration of the mechanisms leading to the outstanding diversity of isoforms expressed from the MAPT gene and the functions in which such isoforms are involved, including their potential role in the onset and development of tauopathies such as Alzheimer’s diseaseThis research received no external fundin
Resultados Perinatales De Hijos De Madres Adolescentes, Comparados Con Hijos De Madres No Adolescentes En Un Hospital De Segundo Nivel En México
OBJECTIVE: To determine perinatal outcomes of children of adolescent mothers against the ones of children of non-adolescent mothers in a second level class hospital in Mexico. METHODOLOGY: Case-control studies applied at “Hospital del Niño y la Mujer” from the National Health Department of Queretaro, Qro. from September 1st, 2015 to January 30th, 2016. A sample of 60 medical records of teenage pregnant women was studied. In addition to 90 medical records of women between 20 to 35 years old who had an obstetric event. The analysis was performed using descriptive and inferential statistics. With a 95% confidence interval and a value of p < 0.05. RESULTS: The average age range was 17.38 and 25.33 respectively. The quantitative variables, statistically significant with a p<0.05, were: weight and Apgar score one minute after birth, whereas in weeks of gestation, height and Apgar score five minutes after birth and after days of hospitalization, there was no change. The most frequent qualitative variables among adolescent women were: complications during childbirth (15%), complications with the newborn (18.3%), and route of termination of pregnancy by caesarean section (70%), while in pregnant women between 20 to 35 years old, the complications during the pregnancy were more frequent (51.1%). CONCLUSIONS: Pregnancy among adolescent women continues to have a higher mortality rate than in 20 to 35 year-old women, although it is less frequent than in previous years. It is necessary to promote sexual education to reduce the incidence in this age group
Mitophagy Failure in APP and Tau Overexpression Model of Alzheimer’s Disease.
Mitochondrial alterations and oxidative stress are common features of Alzheimer’s disease brain and peripheral
tissues. Moreover, mitochondrial recycling process by autophagy has been found altered in the sporadic form of the disease.
However, the contribution of the main proteins involved in this pathology such as amyloid- protein precursor (A PP) and tau
needs to be achieved.With this aim, human unmodified fibroblasts were transduced with lentivectors encoding APP and Tau
and treated with CCCP to study the mitophagy process. Both A PP and tau separately increased autophagy flux mainly by
improving degradation phase. However, in the specific case of mitophagy, labeling of mitochondria by PINK1 and PARK2 to
be degraded by autophagy seemed reduced, which correlates with the long-term accumulation of mitochondria. Nevertheless,
the combination of tau and A PP was necessary to cause a mitophagy functional impairment reflected in the accumulation
of depolarized mitochondria labeled by PINK1. The overexpression of Tau and APP recapitulates the mitophagy failure
previously found in sporadic Alzheimer’s diseasepre-print3421 K
European and Spanish Language Policies: The Road to Change in Tertiary Education
La misión de la universidad es dotar al alumnado con recursos para el
mercado de trabajo y dar formación en un mundo globalizado. Las lenguas y sus culturas
son instrumentos esenciales en la sociedad multilingüe en la que desarrollamos nuestro
potencial como ciudadanos. Las políticas lingüísticas salvaguardan y facilitan la igualdad
de oportunidades en el mercado laboral y es por este papel central por lo que se convierten
en objeto de estudio en contextos educativos. El Consejo de Europa, la Comisión Europea
y el Centro de Lenguas de Graz en sus recomendaciones identifican al plurilingüismo como
principio básico de las políticas lingüísticas y el enfoque AICLE como itinerario eficaz
para alcanzar este objetivo. España acogió con gran entusiasmo este enfoque desde sus
comienzos y ha llegado a ser enclave de referencia en su implantación. En la educación
superior el desarrollo ha sido heterogéneo en primera instancia. Las políticas lingüísticas
europeas llegan a la educación terciaria española de la mano de la implantación previa en
educación primaria y secundaria, permitiendo completar el círculo de la oferta educativa
multilingüe. Las recientes medidas tomadas por la CRUE y ACLES intentan establecer
un marco común en la promoción del multilingüismo en la universidad española.The mission of universities is to equip students with skills for the labour
market and provide training for our global world. Languages and cultures are key tools in
our multilingual social reality where our potential as citizens of the world is developed.
Thus, language policies safeguard and facilitate the equality of opportunities, and it is in
this central role they become an object of study in educational contexts. The Council of
Europe, the European Commission and the European Centre of Modern Languages (Graz)
recommends multilingualism as a basic principle and a central objective of language
policies, and advocates CLIL as the path to reach the goal. Spain embraced multilingual
projects right from the start and has become a landmark in their implementation; however,
in higher education, their development has been rather heterogeneous from the beginning.
Multilingual language policies were first developed in primary and secondary education,
paving the way for its further expansion to tertiary education and, therefore, closing the
circle of multilingual provision. Recent measures issued by the Chancellors’ Conference and the Association of Higher Education Language Centres attempt to set the path for a
common framework in the promotion of multilingualism in Spanish universities
PRINCIPALES FACTORES DE RIESGO EN LA TERCERA EDAD. SU PREVENCIÓN: PRINCIPALES FACTORES DE RIESGO EN LA TERCERA EDAD
The objective of the work was to analyze the main factors of risk that affect to people of the third age and the participation of the family in its prevention. For the development of this work twenty-four up-to-date bibliographies were revised, related with the branches of the medicine that you/they study to this population group that is the gerontology and the geriatrics. The bibliographical search on the biggest adult and how the family is a decisive factor in a pleasant and active age you could concert that the old men are prone to the falls and to suffer of illnesses that are characteristic of the age to the organism not to respond similar to certain changes in the means where they move and they develop, it is necessary that the family knows their symptoms and the most important thing its prevention like part of the development of this stage of the life in a calm way and achieving the biggest autonomy in the caretaker's old man, of walkways and canes.El objetivo del trabajo fue analizar los principales factores de riesgo que afectan a las personas de la tercera edad y la participación de la familia en su prevención. Para el desarrollo de este trabajo se revisaron veinticuatro bibliografías actualizadas, relacionadas con las ramas de la medicina que estudian a este grupo poblacional que es la gerontología y la geriatría. La búsqueda bibliográfica sobre el adulto mayor y cómo la familia es un factor determinante en una vejez agradable y activa se pudo concertar que los ancianos son propensos a las caídas y a padecer de enfermedades que son propias de la edad al organismo no responder igual a ciertos cambios en el medio donde se mueven y desarrollan, es necesario que la familia conozca sus síntomas y lo más importante su prevención como parte del desarrollo de esta etapa de la vida de forma tranquila y logrando la mayor autonomía del anciano del cuidador, de andadores y bastones
The role of spirituality and religiosity in healthcare during the COVID-19 pandemic: an integrative review of the scientific literature
The pandemic caused by the new coronavirus SARS-CoV-2 has been afecting
populations globally since the end of 2019. Previous studies have indicated that
spirituality in these times of crisis serves as a source of hope and well-being that
helps people get through the day. This study investigated the role of spirituality and
religiosity in healthcare during the COVID-19 pandemic. An integrative review of
the scientifc literature available on PubMed, Scopus, and Web of Science databases
and a review of the gray literature in the Information System on Gray Literature in
Europe (OpenGrey) were carried out. From a total of 1,338 articles searched; 25
articles were included in this review (22 quantitative observational, 2 qualitative and
one randomized controlled trial). Our fndings revealed the importance of includ ing spirituality in clinical practice for both health professionals and patients. On the
one hand, spirituality can be considered a good coping strategy used by healthcare
professionals to promote mental health and well-being during the COVID-19 pan demic and resulting in greater patient satisfaction with the care given. On the other
hand, addressing spiritual needs of individuals leads to a reduction in stress, anxiety,
depression, and an increase in resilience and hope among patients
Approach to phytotechnology regulatory and market trends in Europe: future perspectives
info:eu-repo/semantics/publishedVersio
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