Interacciones y percepciones en procesos de mediación tecnológica Caso: experiencia de aprendizaje mediada a través de un grupo en whatsapp como complemento para el desarrollo de habilidades comunicativas en un curso básico de inglés

La presencia de las tecnologías de la información y la comunicación en la educación y su consideración en diferentes contextos de aprendizaje se ha vuelto un tema ineludible que merece una mirada más cercana para analizar su pertinencia y uso dentro de un ambiente de estudio formal. Con el auge de las redes social y en especial el WhatsApp, se tuvo como objetivo general en la presente investigación, de carácter cualitativo, comprender las relaciones que se dieron entre las interacciones y las percepciones de los participantes de un curso básico de inglés a través de la implementación de un grupo en la red social como herramienta de apoyo al proceso de aprendizaje del inglés de un grupo de estudiantes de nivel básico del SENA (Servicio Nacional de Aprendizaje) en Colombia..

Interacciones y percepciones en procesos de mediación tecnológica Caso: experiencia de aprendizaje mediada a través de un grupo en whatsapp como complemento para el desarrollo de habilidades comunicativas en un curso básico de inglés

La presencia de las tecnologías de la información y la comunicación en la educación y su consideración en diferentes contextos de aprendizaje se ha vuelto un tema ineludible que merece una mirada más cercana para analizar su pertinencia y uso dentro de un ambiente de estudio formal. Con el auge de las redes social y en especial el WhatsApp, se tuvo como objetivo general en la presente investigación, de carácter cualitativo, comprender las relaciones que se dieron entre las interacciones y las percepciones de los participantes de un curso básico de inglés a través de la implementación de un grupo en la red social como herramienta de apoyo al proceso de aprendizaje del inglés de un grupo de estudiantes de nivel básico del SENA (Servicio Nacional de Aprendizaje) en Colombia..

Genomic variability in Mexican chicken population using Copy Number Variation

Copy number variants (CNVs) are polymorphisms which influence phenotypic variation and are an important source of genetic variability [1]. In Mexico the backyard poultry population is a unique widespread Creole chicken (Gallus gallus domesticus) population, an undefined cross among different breeds brought to Mexico from Europe and under natural selection for almost 500 years [2-3]. The aim of this study was to investigate genomic variation in the Mexican chicken population using CNVs.A total of 256 DNA samples genotyped with Axiom® Genome-Wide Chicken Genotyping Array were used in the analyses. The individual CNV calling, based on log-R ratio and B-allele frequency values, was performed using the Hidden Markov Model (HMM) of PennCNV software on the autosomes [4-5]. CNVs were summarized to CNV regions (CNVRs) at a population level (i.e. overlapping CNVs), using BEDTools.The HMM detected a total of 1924 CNVs in the genome of 256 samples resulting, at population level, in 1216 CNV regions, of which 959 gains, 226 losses and 31 complex CNVRs (i.e. containing both losses and gains), covering a total of 47 Mb of sequence length corresponding to 5,12 % of the chicken galGal4 assembly autosome. A comparison among this study and 7 previous reports about CNVs in chicken was performed, finding that the 1,216 CNVRs detected in this study overlap with 617 regions (51%) mapped by others studies. This study allowed a deep insight into the structural variation in the genome of unselected Mexican chicken population, which up to now has not been never genetically characterized with SNP markers. Based on a cluster analysis (pvclust – R package) on CNV markers the population, even if presenting extreme morphological variation, does not resulted divided in differentiated genetic subpopulations. Finally this study provides a CNV map based on the 600K SNP chip array jointly with a genome-wide gene copy number estimates in Mexican chicken population.

Acontecimientos vitales y hospitalización psiquiátrica en pacientes maniacos.

Se investigó la incidencia de AV en los seis meses previos al ingreso psiquiátrico y de AV ocurridos durante la infancia en un grupo de 27 pacientes ingresados por un episodio maníaco en un Hospital Psiquiátrico y se comparó con 24 pacientes traumatológicos ingresados en un Hospital General por patología aguda. El grupo de pacientes maniacos presentó más del doble de AV independientes que el grupo control, sin que se encontrasen diferencias significativas en cuanto a la incidencia de AV precoces. Se estudió también el tipo de A V yla relación entre la presencia de éstos y el número de ingresos psiquiátrico

Acontecimientos vitales y hospitalización psiquiátrica en pacientes maniacos.

Se investigó la incidencia de AV en los seis meses previos al ingreso psiquiátrico y de AV ocurridos durante la infancia en un grupo de 27 pacientes ingresados por un episodio maníaco en un Hospital Psiquiátrico y se comparó con 24 pacientes traumatológicos ingresados en un Hospital General por patología aguda. El grupo de pacientes maniacos presentó más del doble de AV independientes que el grupo control, sin que se encontrasen diferencias significativas en cuanto a la incidencia de AV precoces. Se estudió también el tipo de A V yla relación entre la presencia de éstos y el número de ingresos psiquiátrico

Effects of a Short-Term Resistance-Training Program on Heart Rate Variability in Children With Cystic Fibrosis—A Randomized Controlled Trial

[EN] Background: Cystic fibrosis (CF) affects the autonomic nervous system (ANS) and exercise in healthy children modulates the interaction between sympathetic and parasympathetic activity. This study aimed to evaluate the effects of a short-term resistance exercise program on heart rate variability (HRV) in children and adolescents with CF. Methods: A randomized controlled trial was carried out in children diagnosed with CF aged 6–18 years. Individuals were divided into two groups: control (CON) and resistance-training (EX). Individuals in the EX group completed an individualized guided resistance program (5-RM—60–80%) for 8 weeks (3 sessions of 60 min/week). Upper and lower limbs exercises (seated bench press, seated lateral row, and leg press) were used. HRV was measured using a Suunto watch with subjects in lying position. Results: Nineteen subjects (13 boys) were included (CON = 11; and EX = 8). Mean age was 12.2 ± 3.3, FEV1 (forced expiratory volume in the first second) z-score was 1.72 ± 1.54 and peak oxygen consumption (VO2peak) 42.7 ± 7.4 mL.Kg–1.min–1. Exercise induced significant changes in the frequency-domain variables, including a decrease in LF power (p = 0.001, d = 0.98) and LF/HF ratio (p = 0.020, d = 0.92), and an increase in HF power (p = 0.001, d = −0.97), compared to the CON group. No significant changes were found for time-domain variables, although increases with a moderate effect size were seen for SDNN (p = 0.152, d = −0.41) and RMSSD (p = 0.059, d = −0.49) compared to the CON group.SICatedra Fundación Asisa-UE y Universidad Europe

Genomic Diversity Using Copy Number Variations in Worldwide Chicken Populations

Recently, many studies in livestock have focused on the identification of Copy Number Variants (CNVs) using high-density Single Nucleotide Polymorphism (SNP) arrays, but few have focused on studying chicken ecotypes coming from many locations. CNVs are polymorphisms, which may influence phenotype and are an important source of genetic variation in populations. The aim of this study was to explore the genetic difference and structure, using a high density SNP chip in 936 individuals from seven different countries (Brazil, Italy, Egypt, Mexico, Rwanda, Sri Lanka and Uganda). The DNA was genotyped with the Affymetrix Axiom®600k Chicken Genotyping Array and processed with stringent quality controls to obtain 559,201 SNPs in 915 individuals. The Log R Ratio (LRR) and the B Allele Frequency of SNPs were used to perform the CNV calling with PennCNV software based on a Hidden Markov Model analysis and the LRR was used to perform CNV detection with SVS Golden Helix software.After filtering, a total of 19,027 CNVs were detected with the SVS software, while 9,065 CNVs were identified with the Penn CNV software. The CNVs were summarized in 7,001 Copy Number Variant Regions (CNVRs) and 4,414 CNVRs, using the software BedTool.The consensus analysis across the CNVRs allowed the identification of 2,820 consensus CNVR, of which 1,721 were gain, 637 loss and 462 complex, for a total length of 53 Mb corresponding to the 5 % of the GalGal5 chicken autosomes. Only the consensus CNV regions obtained from both detections were considered for further analysis.The intersection analysis performed between the chicken gene database (Gallus_gallus-5.0) and the 1,927 consensus CNVRs allowed the identification (within or partial overlap) of a total of 2,354 unique genes with an official gene ID.  The CNVRs identified here represent the first comprehensive mapping in several worldwide populations, using a high-density SNP chip

Influence of air temperature on drying kinetics and antioxidant potential of olive pomace

This work aims to evaluate the influence of olive pomace drying (a solid by-product of the olive oil industry) on both antioxidant potential and drying kinetics. The two main fractions of olive pomace (pits, PI and pulps + peels, P + P) were characterized by image analysis and density measurement. The drying process was analyzed in experiments carried out at different temperatures (from 50 to 150 C) and mathematically described from the diffusion and Weibull models. The antioxidant potential of the extracts (ethanol water 80:20 v/v, 22 ± 1 C, 170 rpm for 24 h) obtained from the dry product was analyzed by measuring the total phenolic content and antioxidant capacity and the main polyphenols were quantified by HPLC DAD/MS MS. The drying behavior of olive pomace was well described by considering the diffusion in the PI and P + P fractions separately and the influence of temperature on effective moisture diffusivities was quantified by an Arrhenius type equation. The antioxidant potential was only mildly influenced by the drying temperature. However, long drying times at the highest temperature tested (150 C) significantly (p < 0.05) increased the antioxidant potentialThe authors acknowledge the Generalitat Valenciana (PROMETEO/2010/062 and PROMETEO/2012/007) and Ministerio de Economia y Competitividad (AGL2011-29857-C03-04) for their financial support and the Ministerio de Educacion, Cultura y Deporte of Spain for the financing through the Formacion de Profesorado Universitario del Programa Nacional de Formacion de Recursos Humanos de Investigacion.Ahmad-Qasem Mateo, MH.; Barrajón Catalán, E.; Micol, V.; Cárcel Carrión, JA.; García Pérez, JV. (2013). Influence of air temperature on drying kinetics and antioxidant potential of olive pomace. Journal of Food Engineering. 119(3):516-524. https://doi.org/10.1016/j.jfoodeng.2013.06.027S516524119

PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer

To identify a group of patients who might benefit from the addition of weekly paclitaxel to conventional anthracycline-containing chemotherapy as adjuvant therapy of node-positive operable breast cancer. The predictive value of PAM50 subtypes and the 11-gene proliferation score contained within the PAM50 assay were evaluated in 820 patients from the GEICAM/9906 randomized phase III trial comparing adjuvant FEC to FEC followed by weekly paclitaxel (FEC-P). Multivariable Cox regression analyses of the secondary endpoint of overall survival (OS) were performed to determine the significance of the interaction between treatment and the (1) PAM50 subtypes, (2) PAM50 proliferation score, and (3) clinical and pathological variables. Similar OS analyses were performed in 222 patients treated with weekly paclitaxel versus paclitaxel every 3 weeks in the CALGB/9342 and 9840 metastatic clinical trials. In GEICAM/9906, with a median follow up of 8.7 years, OS of the FEC-P arm was significantly superior compared to the FEC arm (unadjusted HR = 0.693, p = 0.013). A benefit from paclitaxel was only observed in the group of patients with a low PAM50 proliferation score (unadjusted HR = 0.23, p < 0.001; and interaction test, p = 0.006). No significant interactions between treatment and the PAM50 subtypes or the various clinical–pathological variables, including Ki-67 and histologic grade, were identified. Finally, similar OS results were obtained in the CALGB data set, although the interaction test did not reach statistical significance (p = 0.109). The PAM50 proliferation score identifies a subset of patients with a low proliferation status that may derive a larger benefit from weekly paclitaxel. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s10549-013-2416-2) contains supplementary material, which is available to authorized users