Instalaciones de clínica de fisioterapia y podología

Traballo fin de grao (UDC.EPS). Enxeñaría en tecnoloxías industriais. Curso 2015/201

Synthesis of enantiomeric polyhydroxyalkylpyrrolidines from 1,3-dipolar cycloadducts. Evaluation as inhibitors of a β-galactofuranosidase

Enantiomeric 2,3,4-tris(hydroxyalkyl)-5-phenylpyrrolidines have been synthesized from the major cycloadducts obtained by the 1,3-dipolar cycloaddition of sugar enones with azomethine ylides derived from natural amino acids. Reduction of the ketone carbonyl group of the cycloadducts, which possess a basic structure of bicyclic 6-(menthyloxy)hexahydropyrano[4,3-c]pyrrol-7(6H)one, afforded a number of pyrrolidine-based bicyclic systems. A sequence of reactions, which involved hydrolysis of the menthyloxy substituent, reduction, N-protection, and degradative oxidation, afforded varied pyrrolidine structures having diverse configurations and patterns of substitution; in particular, polyhydroxylated derivatives have been obtained. The unprotected products were isolated as pyrrolidinium trifluoroacetates. Because of the furanose-like nature of the target trihydroxyalkyl pyrrolidines, these molecules have been evaluated as inhibitors of the β-galactofuranosidase from Penicillium fellutanum. The compounds showed practically no inhibitory activity for concentration of pyrrolidines in the range of 0.1–1.6 mM.Fil: Oliveira Udry, Guillermo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Repetto, Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Vega, Daniel Roberto. Comisión Nacional de Energía Atómica. Centro Atómico Constituyentes. Gerencia de Investigación y Aplicaciones; Argentina. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Varela, Oscar Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentin

Implementação de desmonte com explosivos em Timor-Leste: proposta exploratória

O principal objetivo deste trabalho foi analisar a variação do custo do desmonte com recurso a explosivos em função da escavabilidade do maciço rochoso. Para tal, foram acompanhadas e monitorizados quatro pegas de fogo P1, P3 e P4, da Pedreira de Serdedelo e P2, da Pedreira Fornelo. Antes da implementação do diagrama de fogo e respetiva execução das operações do desmonte, foram previamente bem definidos os locais de cada pega, e, individualmente, realizada uma caracterização do maciço rochoso a desmontar, através de um rigoroso levantamento de cada bancada, recorrendo á técnica de amostragem linear e esclerómetro portátil. Seguidamente, das quatro pegas de fogo, foram registados todos os parâmetros do desmonte e quantificados todos os custos associados aos trabalhos desenvolvidos para as mesmas, desde o levantamento das descontinuidades para caracterização do maciço rochoso a desmontar, até à fragmentação secundária com recurso a meios mecânicos para redução dos calibres resultantes do desmonte que ficaram acima do recomendado para a alimentação do primário. Com base no ábaco Pettifer & Fookes (1994), foi classificada, quanto à sua escavabilidade, o maciço presente em cada bancada a desmontar. Foi criada uma grelha em cima do abaco Pettifer & Fookes (1994), para a respetiva projeção de cada pega no mesmo, com indicação do seu custo unitário de desmonte. Foi realizado este mesmo exercício para uma pega em Timor-Leste, onde são utilizados apenas meios mecânicos para o desmonte, e foi projetado um desmonte teórico com recurso a explosivos, para comparação dos custos do desmonte de diferentes técnicas. A pega P3 apresenta a menor escavabilidade e consequentemente o custo mais elevado (2,463 €/m3 ), em oposição a P2 apresenta a melhor escavabilidade e o menor custo (1,854 €/m3 ). O desmonte mecânico em Timor-Leste tem, atualmente, um custo de 3,39 €/m3 , enquanto a projeção teórica de uma pega com recurso a explosivos tem um custo estimado de 1,450 €/m3 . Podemos concluir que existe uma assinalável relação entre a escavabilidade do maciço rochoso e o respetivo custo do desmonte. Na pega de Timor-Leste, fica clara a grande mais valia económica do desmonte a fogo, quando comparado com o desmonte com meios mecânicos para maciços neste espectro de escavabilidade.The main objective of this study is to analyze the variation of the rock cost blasting cost using explosives according to the excavatability of the rock mass. To achieve this, four blasting projects were carried out and monitored. Blasting P1, P3 and P4 are from the Serdedelo Quarry, while blasting P2 is from the Fornelo Quarry. The locations of each blasting were defined before applying and executing the project design of blasting operations. The rock mass to be excavated was individually characterized by rigorous data collectors of each bench using the scanline sample techniques and Schmidt hammer. All the parameters of the blasting were recorded, and quantified all the costs associated with the four blasting operations, covered from field surveying of the bench, characterizing the rock mass to be excavated up to the secondary fragmentation, using hydraulic breaking to reduce the large rock blocks that exceeded the recommended primary feed. Based on the abacus Pettifer & Fookes (1994), each bench to be excavated was classified as to its excavatability whereby a grid was created over abacus for each of the aforementioned rock blasting operations and indicating their unit costs. The same assignment was carried out for a blasting in Timor-Leste, where only mechanical excavations are used for breaking the rocks, and a theoretical blasting with explosives was designed to compare the costs of different techniques of excavation. Blasting P3 has the lowest excavatability and therefore showed the highest cost of (2.463 €/m3 ), while blasting P2 has the best excavatability and with the lowest cost of (1.854 €/m3 ). The mechanical excavation in TimorLeste has a cost of 3.39 €/m3 , while the theoretical blasting has estimated cost of 1.45 €/m3 . We can conclude therefore, that there is a remarkable relationship between the rock mass excavatability and the respective cost of the blasting. Timor-Leste's blasting clearly proved the great economic value compared to mechanical excavation for the rock masses of this range of excavatability

Causal explanations for the evolution of ‘low gear’ locomotion in insular ruminants

Aim: Mammals on islands often undergo remarkable evolutionary changes. The acquisition of ‘low gear’ locomotion, namely short and robust limb elements, has been typically associated with the island syndrome in large mammals and, especially, ruminants. Here we provide an investigative framework to examine biotic and abiotic selective factors hypothesized to influence evolution of this peculiar type of gait. Location: Islands worldwide. Taxon: Bovidae. Methods: We calculated response variables associated with ‘low gear’ locomotion in 21 extinct and extant insular bovids. We assembled data on the physiography of 11 islands and on life history and ecological traits of the focal taxa. We estimated 10 predictors (island area and four topographic indices, body mass, body size divergence, number of predators and competitors, large mammal richness) and used multiple regressions, regression trees, and random forests to assess their contextual importance. Results: The acquisition of ‘low gear’ locomotion generally happens on islands with a small number of competitors. However, the roughness of the island terrain appears to be also important, without being a main driver. Finally, although the most extreme cases of ‘low gear’ locomotion occurred on islands with no mammalian predators, our models show a non-significant relationship with this factor. Main conclusions: The evolution of ‘low gear’ locomotion in insular ruminants does not simply result from phyletic dwarfing and predatory release. Variation in morphological responses within Bovidae to ecological and topographic traits suggests, instead, a complex interplay of biotic and abiotic factors. Current understanding on the main drivers of species evolutionary pathways and biogeographic patterns are disproportionally based on few taxa, mainly vertebrates, and in some extreme cases (like this one) even on few species. Here we show how adding more data, even within the same taxonomic group, can challenge historically accepted macroevolutionary and macroecological concepts

Realidad aumentada y secuencias didácticas como elementos de mejora en la educación matemática y la formación permanente del profesorado

Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Formación de Profesorado y Educación. Departamento de Didáctica y Teoría de la Educación. Fecha de lectura: 26 de junio de 201

Grain size effect on the electrical response of SnO2 thin and thick film gas sensors

Porous nano and micro crystalline tin oxide films were deposited by RF Magnetron Sputtering and doctor blade techniques, respectively. Electrical resistance and impedance spectroscopy measurements, as a function of temperature and atmosphere, were performed in order to determine the influence of the microstructure and working conditions over the electrical response of the sensors. The conductivity of all samples increases with the temperature and decreases in oxygen, as expected for an n-type semiconducting material. The impedance plots indicated the existence of two time constants related to the grains and the grain boundaries. The Nyquist diagrams at low frequencies revealed the changes that took place in the grain boundary region, with the contribution of the grains being indicated by the formation of a second semicircle at high frequencies. The better sensing performance of the doctor bladed samples can be explained by their lower initial resistance values, bigger grain sizes and higher porosity.Fil: Savu, Raluca. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Ponce, Miguel Adolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Joanni, Ednan. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Bueno, Paulo Roberto. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Castro, Miriam Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Cilense, Mario. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Varela, Jose Arana. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Longo, Elson. Universidade Estadual Paulista Julio de Mesquita Filho; Brasi

Satisfacción Laboral y Compromiso Organizacional, Docentes Institución Educativa Libertador José de San Martín, Lima 2020

La investigación que se presenta \"Satisfacción laboral y compromiso organizacional en docentes, Institución Educativa Libertador José de San Martín, Lima 2020\", la cual en su objetivo busca conocer la relación entre satisfacción laboral y compromiso organizacional, en la institución educativa mencionada. Se manejó en tipo aplicada, nivel descriptivo correlacional, enfoque cuantitativo; con un diseño no experimental transversal. El muestreo probabilístico siendo la muestra 58 docentes. Técnica que se tuvo es la encuesta, mientras se aplicó la Escala Satisfacción Laboral SL-SPC Palma (2006) además la Escala de Compromiso Organizacional. Meyer y Allen (1997), que tradujo Arciniega & Gonzales (2006), y adaptó Argomedo (2013). Los resultados fueron de satisfacción laboral 22 docentes (37.9%) se encuentran insatisfechos y 14 docentes (24.1%) están satisfechos; asimismo en compromiso organizacional se tuvo 46 docentes calificaron en la categoría Fuerte haciendo un 79.31% y para la categoría Moderado lo hicieron 12 con un 20.69%, dejando desierta la categoría Débil. Dicho esto, concluye no se relación a la Satisfacción Laboral y Compromiso Organizacional, siendo p, 688, que evidencia un grado valorativo atribuido al docente para estar satisfecho con su institución es de interés mínimo refiriéndose a incrementar el compromiso organizacional.Tesi

Desarrollo de un sistema web para planificación docente en la Unidad Educativa “Juan XXIII”.

En la presente investigación se desarrolló una aplicación web que automatice los procesos que intervienen en la planificación curricular docente y de actividades complementarias en la Unidad Educativa Fisco Misional “Juan XXIII”. Para la elaboración de la aplicación web se trabajó sobre el sistema operativo de Windows, utilizando un servidor de base de datos PostgreSQL, 9.6, el entorno de desarrollo integrado NetBeans 8.02 RC, para los reportes Itext 4.2 y JasperReport 4.2 , de la misma forma el framework PrimeFaces 6.0, y para el despliegue de la aplicación el servidor GlassFish 4.1. Se realizaron métodos de recolección de información como: entrevista, encuesta, lluvia de ideas, debate, foros; tanto a los directivos de la institución educativa, así como también a un sector de los docentes que ocupan los cargos tanto de coordinadores como colectivos. Y se aplico la metodología de desarrollo SCRUM, lo que permitió realizar la entrega de los productos en los tiempos establecidos por el cliente. La aplicación cuenta con control de usuario los mismos que se manejan en 4 roles: Administrados, Rector, Vicerrector, Coordinador, Colectivo y Docente. Para evaluar la eficiencia de la aplicación se utilizo la norma ISO/IEC 25010, a partir de la cual se estableció un test en 2 fases para verificar el cumplimiento de la norma, para lo cual se realizo un simulacro con la totalidad de los docentes de la Institución concluyendo que la mayor parte de la comunidad docente cuenta con acceso a conectividad y acceso tecnológico teniendo un mínimo de rechazo de la aplicación y se puede hacer la recomendación de que para llevar a cabo el proceso de recolección de información se utilicen los métodos virtuales debido a la falta de disponibilidad de educación presencial, además se recomienda que se establezcan los procesos a automatizar y los que no, teniendo en cuenta que algunas de las tareas realizadas por los docentes necesitan de manera obligatoria una parte física.In the current research, we developed a web application that automates the processes of the teaching curriculum planning and complementary activities in the Unidad Educativa Fisco Misional “Juan XXIII”., We worked on the Windows operating system for the development of the web application using a PostgreSQL database server 9.6, the NetBeans 8.02 RC integrated development environment, JasperReport 4.2 reports, and the PrimeFaces 6.0 framework for the Itext reports 4.2 and the GlassFish 4.1 server for application deployment. We carried out information gathering methods such as: interview, survey, brainstorming, debate, forums both with the directors of the educational institution, as well as with the teachers who are coordinators as collectives. We applied The SCRUM development methodology which allowed the delivery of the products in the times established by the client. The application contains user control that is managed by roles: Administrator, Rector, Vice-Rector, Coordinator, Collective and Teacher. We used the ISO / IEC 25010 Standard to evaluate the efficiency of the application, from which we established a 2-phase test to verify accomplishment of the standard, where a simulation with all the teachers of the Institution was carried out concluding that most of the teaching community has access to connectivity and technological access having a minimum rejection of the application. We recommend establishing the processes that need to be automated and those that do not need to be automated, taking into consideration that some of the tasks performed by teachers necessarily require a physical part

Biotechnology in Argentine agriculture faces world-wide concentration

In the 1980s, the technical pattern of production in agriculture changed due to the increasing design of genetically modified plants. Modern biotechnology thrived on events requiring certain thresholds of scientific and technological skills as well as scale economies usually seen in developed countries. The mergers and acquisitions during the mid-1990s led to a world-wide oligopoly composed of very few agri-biotechnological mega-corporations and the literature discusses the impact of the mergers and acquisitions on the agriculture of developing countries with comparative advantages in agriculture. This paper analyzes the world-wide process of agri-biotechnological mega-corporation mergers and acquisitions as well as its impact and interrelationships with Argentine agriculture using information from primary and secondary sources. Conclusions refer to the set-backs of endogenous agri-biotechnological development due to world-wide concentration in developing countries with comparative advantage in agriculture