Fission cross section measurements for 240Pu, 242Pu

This report comprises the deliverable 1.5 of the ANDES project (EURATOM contract FP7-249671) of Task 3 "High accuracy measurements for fission" of Work Package 1 entitled "Measurements for advanced reactor systems". This deliverables provide evidence of a successful completion of the objectives of Task 3.JRC.D.4-Standards for Nuclear Safety, Security and Safeguard

A compact fission detector for fission-tagging neutron capture experiments with radioactive fissile isotopes

© 2020 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).In the measurement of neutron capture cross-sections of fissile isotopes, the fission channel is a source of background which can be removed efficiently using the so-called fission-tagging or fission-veto technique. For this purpose a new compact and fast fission chamber has been developed. The design criteria and technical description of the chamber are given within the context of a measurement of the 233U(n, γ) cross-section at the n_TOF facility at CERN, where it was coupled to the n_TOF Total Absorption Calorimeter. For this measurement the fission detector was optimized for time resolution, minimization of material in the neutron beam and for alpha-fission discrimination. The performance of the fission chamber and its application as a fission tagging detector are discussed.Peer reviewe

DEFORMABILITY OF A FLAX REINFORCEMENT FOR COMPOSITE MATERIALS

In this work, the deformability of a flax fabric adopted as composite reinforcement is experimentally investigated. The fabric (commercialized as FLAXPLY UD 180 by LINEO) is a quasi-unidirectional woven fabric with thin weft yarns connecting thick slightly twisted warp using satin weave interlacing pattern. The study is dedicated to the understanding and measurement of the main deformation mechanisms occurring during forming processes. The deformation during extension is investigated under uniaxial and biaxial loading in the in-plane tow directions (i.e. warp and weft). Particular attention is dedicated to the behavior during shear loading because this is considered the primary deformation mechanism in the reinforcement forming. Uniaxial bias extension and picture frame tests are adopted to measure the shear deformation. The tests are assisted by digital image correlation (DIC) technique to have a continuous measurement of the local deformation in the fabric plane during loading

Quasi-unidirectional flax composite reinforcement: Deformability and complex shape forming

Deformability and complex shape forming of a quasi-unidirectional flax reinforcement for composite materials (commercialized as FLAXPLY UD 180 by LINEO) are experimentally investigated. The first part of the study is focused on the understanding and measurement of the main deformation modes: in-plane tension, in-plane shear, and out-of-plane bending and compression, which are involved during draping of composite reinforcements. The second part is dedicated to the experimental study of a complex 3D shape forming, namely double-dome. The obtained results represent a complete data set for the characterisation of the deformation capabilities of the quasi-unidirectional flax reinforcement during complex 3D shape forming processes and provide benchmarking data for numerical predictions

Forming of a flax reinforcement for composite materials

This research work is focussed on the experimental complex shape forming of a flax fabric adopted as composite reinforcement. The fabric is a quasi-unidirectional woven fabric with thin twisted weft yarns connecting thick warp yarns using a warp rep weave interlacing pattern. The first part of the study is dedicated to the experimental measurement of the main deformation mechanisms of the fabric involved in forming processes: in-plane uniaxial and biaxial tension; in-plane shear; out-of-plane bending and out-of-plane compression. The second part is devoted to the experimental study of a complex 3D shape forming. The formability of the quasi-unidirectional flax reinforcement was observed using a double-dome punch in an open die forming process

Establishment of an Academic Tissue Microarray Platform as a Tool for Soft Tissue Sarcoma Research

Soft tissue sarcoma (STS) is a heterogeneous family of rare mesenchymal tumors, characterized by histopathological and molecular diversity. Tissue microarray (TMA) is a tool that allows performing research in orphan diseases in a more efficient and cost-effective way. TMAs are paraffin blocks consisting of multiple small representative tissue cores from biological samples, for example, from multiple donors, diverse sites of disease, or multiple different diseases. In 2015, we began constructing TMAs using archival tumor material from STS patients. Specimens were well annotated in terms of histopathological diagnosis, treatment, and clinical follow-up of the tissue donors. Each TMA block contains duplicate or triplicate 1.0-1.5 mm tissue cores from representative tumor areas selected by sarcoma pathologists. The construction of TMAs was performed with TMA Grand Master (3DHistech). So far, we have established disease-specific TMAs from 7 STS subtypes: gastrointestinal stromal tumor (72 cases included in the array), alveolar soft part sarcoma (n = 12 + 47), clear cell sarcoma (n = 22 + 32), leiomyosarcoma (n = 55), liposarcoma (n = 42), inflammatory myofibroblastic tumor (n = 12 + 21), and alveolar rhabdomyosarcoma (n = 24). We also constructed a multisarcoma TMA covering a representative number of important histopathological subtypes on arrays for screening purposes, namely, angiosarcoma, dedifferentiated liposarcoma, pleomorphic liposarcoma, and myxoid liposarcoma, leiomyosarcoma, malignant peripheral nerve sheath tumor, myxofibrosarcoma, rhabdomyosarcoma, synovial sarcoma, and undifferentiated pleomorphic sarcoma, with 7-11 individual cases per subtype. We are currently expanding the list of TMAs with additional sarcoma entities, considering the heterogeneity of this family of tumors. Our extensive STS TMA platform is suitable for rapid and cost-effective morphological, immunohistochemical, and molecular characterization of the tumor as well as for the identification of potential novel diagnostic markers and drug targets. It is readily available for collaborative projects with research partners

Establishment of an Academic Tissue Microarray Platform as a Tool for Soft Tissue Sarcoma Research

Soft tissue sarcoma (STS) is a heterogeneous family of rare mesenchymal tumors, characterized by histopathological and molecular diversity. Tissue microarray (TMA) is a tool that allows performing research in orphan diseases in a more efficient and cost-effective way. TMAs are paraffin blocks consisting of multiple small representative tissue cores from biological samples, for example, from multiple donors, diverse sites of disease, or multiple different diseases. In 2015, we began constructing TMAs using archival tumor material from STS patients. Specimens were well annotated in terms of histopathological diagnosis, treatment, and clinical follow-up of the tissue donors. Each TMA block contains duplicate or triplicate 1.0–1.5 mm tissue cores from representative tumor areas selected by sarcoma pathologists. The construction of TMAs was performed with TMA Grand Master (3DHistech). So far, we have established disease-specific TMAs from 7 STS subtypes: gastrointestinal stromal tumor (72 cases included in the array), alveolar soft part sarcoma (n = 12 + 47), clear cell sarcoma (n = 22 + 32), leiomyosarcoma (n = 55), liposarcoma (n = 42), inflammatory myofibroblastic tumor (n = 12 + 21), and alveolar rhabdomyosarcoma (n = 24). We also constructed a multisarcoma TMA covering a representative number of important histopathological subtypes on arrays for screening purposes, namely, angiosarcoma, dedifferentiated liposarcoma, pleomorphic liposarcoma, and myxoid liposarcoma, leiomyosarcoma, malignant peripheral nerve sheath tumor, myxofibrosarcoma, rhabdomyosarcoma, synovial sarcoma, and undifferentiated pleomorphic sarcoma, with 7–11 individual cases per subtype. We are currently expanding the list of TMAs with additional sarcoma entities, considering the heterogeneity of this family of tumors. Our extensive STS TMA platform is suitable for rapid and cost-effective morphological, immunohistochemical, and molecular characterization of the tumor as well as for the identification of potential novel diagnostic markers and drug targets. It is readily available for collaborative projects with research partners