SOCIAL CAPITAL AS AN ENABLER FOR SUSTAINABLE KNOWLEDGE MANAGEMENT IN ORGANIZATIONS

While the importance of knowledge management in organizations and its benefits as innovative powers and a competitive edge is a widely accepted notion in our field of research, it lacks contributions that focus on how knowledge management can be performed in a sustainable way. If we rely so strongly on knowledge management, we should strive for it that current knowledge practices respect both present and future knowledge demands. This paper aims to uncover how organizations can stimulate sustainable knowledge management, meaning the extent to which the organization is capable to track and adapt to changes, internally and in its external environment, by seeking its enablers. While it is clear now that an important part of knowledge in organizations resides in the informal networks, we use the concept of social capital as a measure for informal networks in organizations. By assessing 50 Dutch knowledge-intensive organizations, we seek to reveal to what extent the existence of social capital is an enabler for a set of best practices in knowledge management (known as New Knowledge Management) of which its practice is regarded as sustainable knowledge management

Revealing Knowledge Networks From Computer Mediated Communication in Organizations

In today’s knowledge driven economy, knowledge is considered to be the key factor in defining the success of an organization. We have learned that knowledge is residing in the informal network of the organization. Hence, to improve performance, it is the informal knowledge network that should be examined and developed. For this purpose, social network analysis is increasingly applied in business contexts. This is, however, a new domain, which is still in development. This paper aims to aid in this development by researching how representative knowledge networks can be revealed in organizations. While surveying is a common first option to capture an organizational network, this technique may not always be suitable. Communication sources (e.g. e-mail) may provide an alternative, however, we do not know to what extent these sources can represent the actual knowledge network. This paper examines a Dutch IT services organization. Here, a web-survey among the employees baselines the knowledge network, which is compared to 3 communication networks from the same organization, captured by means of e-mail, telephone and SMS (Short Message Service) communication (also known as text messaging or texting). A comparison is made by means of correlating the network matrices and by comparing essential network properties. Findings show that only the e-mail network is significantly representative for the baselined knowledge network. This exercise is exploratory in nature as only one organization is examined, but comprehensive with regard to the richness of data that is available for examination. From our findings we gain insight in the extent to which networks, captured from e-mail, telephone and SMS archives can represent an organizational knowledge network

Mining email to leverage knowledge networks in organizations

There is nothing new about the notion that in today‟s knowledge driven economy, knowledge is the key strategic asset for competitive advantage in an organization. Also, we have learned that knowledge is residing in the organization‟s informal network. Hence, to leverage business performance from a knowledge management perspective, focus should be on the informal network. A means to analyze and develop the informal network is by applying Social Network Analysis (SNA). By capturing network data in an organization, bottlenecks in knowledge processes can be identified and managed. But where network data can easily be captured by means of a survey in small organizations, in larger organizations this process is too complex and time-intensive. Mining e-mail data is more and more regarded as a suitable alternative as it automates the data capturing process and enables longitudinal research possibilities. An increasing amount of tools for mining e-mail data into social networks is available, but the question remains to what extent these tools are also capable of conducting knowledge network analysis: the analysis of networks from a knowledge perspective. It is argued that in order to perform knowledge network analysis, a tool is required that is capable of analyzing both the header data and the body data of e-mail messages. In this paper two e-mail mining tools are elaborated. One focuses on the analysis of e-mail header data and the other focuses on the analysis of e-mail body data. Both tools are embedded in their theoretical background and compared to other e-mail mining tools that address e-mail header data or e-mail body data. The aim of this paper is two-fold. The paper primarily aims at providing a detailed discussion of both tools. Continuing, from the in-depth review, the integration of both tools is proposed, concluding towards a single new tool that is capable of analyzing both e-mail header and body data. It is argued how this new tool nurtures the application of knowledge network analysis

Local enterprise partnerships: Socialisation practices enabling business collective action in regional knowledge networks

This article identifies and theorises the interorganisational socialisation mechanisms that facilitatethe knowledge dynamic capabilities of organisations brought together within the applied contextof a U.K. Local Enterprise Partnership. Focusing on the Sheffield City Region's Creative and Dig-ital Industries Sector Group, the data for this study were messages posted to the Creative andDigital Industries Sector Group's online consultation platform. Data analysis proceeded throughinductive thematic analysis. It is revealed that collaborative workspaces, business networksresources, and pathways to internationalisation are perceived to play an important role in facili-tating interorganisational learning. These knowledge socialisation mechanisms are essential toavoid regional competency traps. The article identifies and discusses knowledge socialisationmechanisms that are perceived to play a key role in transferring knowledge between membersof the regional system of innovation. In identifying and discussing knowledge socialisation mech-anisms, this paper offers knowledge management theorists and practitioners—more specifically,regional knowledge brokers and regional development managers—actionable insight into a rangeof strategies that reinforce social ties and increase the flow of knowledge with a view to improv-ing innovation outcomes

Transcriptomic analysis of the temporal host response to skin infestation with the ectoparasitic mite Psoroptes ovis

<p>Abstract</p> <p>Background</p> <p>Infestation of ovine skin with the ectoparasitic mite <it>Psoroptes ovis </it>results in a rapid cutaneous immune response, leading to the crusted skin lesions characteristic of sheep scab. Little is known regarding the mechanisms by which such a profound inflammatory response is instigated and to identify novel vaccine and drug targets a better understanding of the host-parasite relationship is essential. The main objective of this study was to perform a combined network and pathway analysis of the <it>in vivo </it>skin response to infestation with <it>P. ovis </it>to gain a clearer understanding of the mechanisms and signalling pathways involved.</p> <p>Results</p> <p>Infestation with <it>P. </it>ovis resulted in differential expression of 1,552 genes over a 24 hour time course. Clustering by peak gene expression enabled classification of genes into temporally related groupings. Network and pathway analysis of clusters identified key signalling pathways involved in the host response to infestation. The analysis implicated a number of genes with roles in allergy and inflammation, including pro-inflammatory cytokines (<it>IL1A, IL1B, IL6, IL8 </it>and <it>TNF</it>) and factors involved in immune cell activation and recruitment (<it>SELE, SELL, SELP, ICAM1, CSF2, CSF3, CCL2 </it>and <it>CXCL2</it>). The analysis also highlighted the influence of the transcription factors NF-kB and AP-1 in the early pro-inflammatory response, and demonstrated a bias towards a Th2 type immune response.</p> <p>Conclusions</p> <p>This study has provided novel insights into the signalling mechanisms leading to the development of a pro-inflammatory response in sheep scab, whilst providing crucial information regarding the nature of mite factors that may trigger this response. It has enabled the elucidation of the temporal patterns by which the immune system is regulated following exposure to <it>P. ovis</it>, providing novel insights into the mechanisms underlying lesion development. This study has improved our existing knowledge of the host response to <it>P. ovis</it>, including the identification of key parallels between sheep scab and other inflammatory skin disorders and the identification of potential targets for disease control.</p

De Geschillencommissie Ziekenhuizen. Een nieuwe vorm van geschillenbeslechting in de gezondheidszorg

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