1,010 research outputs found

    Implementation of Health Policy on Establishment of Provincial Center of Diseases Control (CDC) in Vietnam

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    Purpose: There is increasing interest in the understanding of key influences over successful implementation of health policies within ever-changing contexts of national health systems. The epidemiological transition in Vietnam, combined with an urgent need for improving efficiency of the national health system under the government’s administrative reforms, form important facilitators of restructuring the public health system. This paper explored the implementation processes of policy on establishment of the Centers for Diseases Control (CDC) in Vietnam during 2016– 2019. Methods: The study employed a cross-sectional and mixed methods design. Staff surveys were collected at 55 out of 63 provinces and in-depth interviews, focus groups were conducted in three purposefully selected provinces. Quantitative data were analysed using descriptive statistics and qualitative data were analyzed thematically. The innovation implementation framework guided the study. Results: After 3 years of introduction, 82.5% of provinces had established the CDCs. Implementation of CDC establishment policy was influenced by 1) management support; 2) alignment between policy and practice; 3) values towards CDC,; and 4) implementation climate. Other external key influencers included political, social, and cultural factors. Conclusion: Our study provides a framework and evidence to guide future inquiry into the factors that affect the relationship between policy implementation and other contextual factors in healthcare organizations

    Reflectarray Antennas printed on convex surfaces

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    The characteristics of Reflectarray Antennas printed on convex curved surfaces are discussed in this paper. In particular, results will be presented on the radiation performances of Reflectarrays designed to fit cylinders with different radii of curvature, and with different types of radiating elements

    UTJECAJ UVJETA POSTUPKA DOBIVANJA MLJEVENE TROSKE TALJENJEM UGLJENA U VISOKOJ PEĆI UZ UPORABU GEOPOLIMERA

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    In this study, the material characterization of Vietnamese ground coal slag and ground granulated blast furnace slag (GGBFS), such as particle size distribution, chemical composition, bulk density and particle density are shown. The geopolymer specimens were prepared by mixing an 80 m/m% mass of solid materials (ground coal slag and GGBFS in a different ratio) with 20 m/m % of a 10M NaOH alkaline activator. A systematic experimental series was carried out in order to optimize the preparation process. In that series, the heat curing temperature was 60°C for 6 hours, and then selected specimens were heat treated at a high temperature (1000 °C) for 1 hour. After 7 days of ageing, the physical properties of the geopolymer (compressive strength, specimen density) were measured. Also, after 180 days of ageing, the pH values of water in the geopolymer leaching preparation were determined. The results show that the geopolymer can be used for refractory applications due to its good heat resistance properties. However, geopolymers that were heated at 1000 °C had lower compressive strength, specimen density and pH values of water containing the geopolymer than those that were cured at 60 °C.U ovome istraživanju donose se obilježja vijetnamskih granulata ugljene troske i troske željezne rude na osnovi njihove veličine, kemijskoga sastava i gustoće. Uzorci geopolimera pripremljeni su miješanjem 80 % m/m (mase otopljenoga / masa otopine) ugljene i željezne troske (u različitim omjerima) s 20 % m/m 10M NaOH kao alkalnoga aktivatora. Sustavnim serijama eksperimenata optimiziran je postupak pripreme, pri čemu je temperatura iznosila 60 °C tijekom 6 sati, nakon čega su odabrani uzorci zagrijavani 1 sat na 1000 °C. Nakon sljedećih 7 dana izmjerena su fizička svojstva geopolimera (tlačna čvrstoća, gustoća). Zatim je poslije 180 dana određena pH-vrijednost vode korištene u postupku ispiranja geopolimera. Rezultati su pokazali kako geopolimeri mogu biti korišteni za namjene u vatrostalnim uvjetima zahvaljujući toplinskim svojstvima. Također, geopolimeri koji su zagrijavani na 1000 °C imaju niže vrijednosti tlačne čvrstoće, gustoće i pH-vrijednosti vode u njima od onih koji su grijani na 60 °C

    Carbon Footprint Calculator Customized for Rice Products: Concept and Characterization of Rice Value Chains in Southeast Asia

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    In this study, we developed user-friendly software (CF-Rice) for calculating the carbon footprints (CF) of rice products. The approach follows the principles of Life Cycle Assessment while incorporating more flexibility for activities specific to rice production. The graphical user interface provides empirical emission and conversion factors obtained from the literature and from primary research studies of rice value chains. CF-Rice also allows the entering of new values for specific processes or practices. Data outputs distinguish among the contributions of individual stages of the value chain as well as different greenhouse gases (GHG), namely, CH4_{4}, N2_{2}O and CO2_{2}. The new tool was then applied to a scenario assessment of rice production in the regional context of Southeast Asia. The CF baseline of a typical rice value chain in the region accounted for a value of around 2300 g CO2_{2}e/kgProd_{Prod}. The CF can be reduced by about 27.4% through water-saving practices alone and can further be reduced up to 37.3% through interventions that increase product recovery rates and, thus, reduce food losses. In contrast, straw incorporation into the soil increased the CF by 26.0%. The tool is well suited for impact assessments of advanced practices and technologies of rice value chains

    Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition.

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    The epithelial-mesenchymal transition (EMT) endows carcinoma cells with phenotypic plasticity that can facilitate the formation of cancer stem cells (CSCs) and contribute to the metastatic cascade. While there is substantial support for the role of EMT in driving cancer cell dissemination, less is known about the intracellular molecular mechanisms that govern formation of CSCs via EMT. Here we show that β2 and β5 proteasome subunit activity is downregulated during EMT in immortalized human mammary epithelial cells. Moreover, selective proteasome inhibition enabled mammary epithelial cells to acquire certain morphologic and functional characteristics reminiscent of cancer stem cells, including CD44 expression, self-renewal, and tumor formation. Transcriptomic analyses suggested that proteasome-inhibited cells share gene expression signatures with cells that have undergone EMT, in part, through modulation of the TGF-β signaling pathway. These findings suggest that selective downregulation of proteasome activity in mammary epithelial cells can initiate the EMT program and acquisition of a cancer stem cell-like phenotype. As proteasome inhibitors become increasingly used in cancer treatment, our findings highlight a potential risk of these therapeutic strategies and suggest a possible mechanism by which carcinoma cells may escape from proteasome inhibitor-based therapy

    Metrology Needs for Predicting Concrete Pumpability

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    With the increasing use of pumping to place concrete, the development and refinement of the industry practice to ensure successful concrete pumping are becoming important needs for the concrete construction industry. To date, research on concrete pumping has been largely limited to a few theses and research papers. The major obstacle to conduct research on concrete pumping is that it requires heavy equipment and large amounts of materials. Thus, developing realistic and simple measurement techniques and prediction tools is a financial and logistical challenge that is out of reach for small research labs and many private companies in the concrete construction industry. Moreover, because concrete pumping involves the flow of a complex fluid under pressure in a pipe, predicting its flow necessitates detailed knowledge of the rheological properties of concrete, which requires new measurement science. This paper summarizes the technical challenges associated with concrete pumping and the development in concrete pumping that have been published in the technical literature and identifies future research needed for the industry to develop best practices for ensuring successful concrete pumping in the field

    Regional prediction of landslide hazard using probability analysis of intense rainfall in the Hoa Binh province, Vietnam.

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    The main objective of this study is to assess regional landslide hazards in the Hoa Binh province of Vietnam. A landslide inventory map was constructed from various sources with data mainly for a period of 21 years from 1990 to 2010. The historic inventory of these failures shows that rainfall is the main triggering factor in this region. The probability of the occurrence of episodes of rainfall and the rainfall threshold were deduced from records of rainfall for the aforementioned period. The rainfall threshold model was generated based on daily and cumulative values of antecedent rainfall of the landslide events. The result shows that 15-day antecedent rainfall gives the best fit for the existing landslides in the inventory. The rainfall threshold model was validated using the rainfall and landslide events that occurred in 2010 that were not considered in building the threshold model. The result was used for estimating temporal probability of a landslide to occur using a Poisson probability model. Prior to this work, five landslide susceptibility maps were constructed for the study area using support vector machines, logistic regression, evidential belief functions, Bayesian-regularized neural networks, and neuro-fuzzy models. These susceptibility maps provide information on the spatial prediction probability of landslide occurrence in the area. Finally, landslide hazard maps were generated by integrating the spatial and the temporal probability of landslide. A total of 15 specific landslide hazard maps were generated considering three time periods of 1, 3, and 5 years

    Challenges in the harmonisation of global integrated assessment models: a comprehensive methodology to reduce model response heterogeneity

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    Harmonisation sets the ground to a solid inter-comparison of integrated assessment models. A clear and transparent harmonisation process promotes a consistent interpretation of the modelling outcomes divergences and, reducing the model variance, is instrumental to the use of integrated assessment models to support policy decision-making. Despite its crucial role for climate economic policies, the definition of a comprehensive harmonisation methodology for integrated assessment modelling remains an open challenge for the scientific community. This paper proposes a framework for a harmonisation methodology with the definition of indispensable steps and recommendations to overcome stumbling blocks in order to reduce the variance of the outcomes which depends on controllable modelling assumptions. The harmonisation approach of the PARIS REINFORCE project is presented here to layout such a framework. A decomposition analysis of the harmonisation process is shown through 6 integrated assessment models (GCAM, ICES-XPS, MUSE, E3ME, GEMINI-E3, and TIAM). Results prove the potentials of the proposed framework to reduce the model variance and present a powerful diagnostic tool to feedback on the quality of the harmonisation itself
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