63 research outputs found

    Near-infrared ps transient photoinduced absorption in conjugated systems

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    Optical Science, Engineering and Instrumentation '97, 1997, San Diego, CA, United StatesSergey V. Frolov, Werner Gellermann, Z. Valy Vardeny, Masanori Ozaki, Katsumi Yoshino, Thomas J. Barton, and Guglielmo Lanzani "Near-infrared ps transient photoinduced absorption in conjugated systems", Proc. SPIE 3145, Optical Probes of Conjugated Polymers, (1 December 1997). DOI: https://doi.org/10.1117/12.29553

    Ultrafast femtosecond relaxation processes in luminescent and nonluminescent conducting polymers

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    Optical Science, Engineering and Instrumentation '97, 1997, San Diego, CA, United StatesJiandong D. Huang, Sergey V. Frolov, Z. Valy Vardeny, W. Chen, Thomas J. Barton, R. Sugimoto, Masanori Ozaki, and Katsumi Yoshino "Ultrafast femtosecond relaxation processes in luminescent and nonluminescent conducting polymers", Proc. SPIE 3145, Optical Probes of Conjugated Polymers, (1 December 1997). DOI: https://doi.org/10.1117/12.28415

    Adding Spin Functionality to Traditional Optoelectronics via Chiral Perovskite

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    Spin polarized current generation and injection into semiconductors at room temperature are key to enable a broader range of opto-spintronic functionalities, yet the inherent efficiency of spin injection across commonly used semiconductor-ferromagnet interfaces is limited. Here, we demonstrate efficient spin injection into commercially viable III-V light emitting diodes (LED) by integrating chiral halide perovskite layers with (AlxGa1-x)0.5In0.5P multiple quantum wells (MQW). Spin polarized current is injected via chirality induced spin selectivity (CISS) and the spin accumulation in the III-V semiconductor is detected via the emission of circularly polarized light with a degree of circular polarization of up to ~ 15%. X-ray photoemission spectroscopy (XPS) and transmission electron microscopy (TEM) cross sectional imaging indicate a pristine perovskite/III-V interface. These findings demonstrate chiral perovskite semiconductors transform well-developed semiconductor platforms to enable control over spin, charge, and light

    A prospective, open-label, randomized trial of doxycycline versus azithromycin for the treatment of uncomplicated murine typhus

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    Murine typhus, or infection with Rickettsia typhi, is a global but neglected disease without randomized clinical trials to guide antibiotic therapy.; A prospective, open, randomized trial was conducted in nonpregnant, consenting inpatient adults with rapid diagnostic test evidence of uncomplicated murine typhus at 2 hospitals in Vientiane, Laos. Patients were randomized to 7 days (D7) or 3 days (D3) of oral doxycycline or 3 days of oral azithromycin (A3). Primary outcome measures were fever clearance time and frequencies of treatment failure and relapse.; Between 2004 and 2009, the study enrolled 216 patients (72 per arm); 158 (73.2%) had serology/polymerase chain reaction (PCR)-confirmed murine typhus, and 52 (24.1%) were R. typhi PCR positive. The risk of treatment failure was greater for regimen A3 (22.5%; 16 of 71 patients) than for D3 (4.2%; 3 of 71) or D7 (1.4%; 1 of 71) (P < .001). Among R. typhi PCR-positive patients, the area under the time-temperature curve and the fever clearance time were significantly higher for A3 than for D3 (1.8- and 1.9-fold higher, respectively; P = .005) and D7 (1.5- and 1.6-fold higher; P = .02). No patients returned with PCR-confirmed R. typhi relapse.; In Lao adults, azithromycin is inferior to doxycycline as oral therapy for uncomplicated murine typhus. For doxycycline, 3- and 7-day regimens have similar efficacy. Azithromycin use in murine typhus should be reconsidered. Investigation of genomic and phenotypic markers of R. typhi azithromycin resistance is needed.; ISRCTN47812566

    Association of the PHACTR1/EDN1 genetic locus with spontaneous coronary artery dissection

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    Background: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndromes (ACS) afflicting predominantly younger to middle-aged women. Observational studies have reported a high prevalence of extracoronary vascular anomalies, especially fibromuscular dysplasia (FMD) and a low prevalence of coincidental cases of atherosclerosis. PHACTR1/EDN1 is a genetic risk locus for several vascular diseases, including FMD and coronary artery disease, with the putative causal noncoding variant at the rs9349379 locus acting as a potential enhancer for the endothelin-1 (EDN1) gene. Objectives: This study sought to test the association between the rs9349379 genotype and SCAD. Methods: Results from case control studies from France, United Kingdom, United States, and Australia were analyzed to test the association with SCAD risk, including age at first event, pregnancy-associated SCAD (P-SCAD), and recurrent SCAD. Results: The previously reported risk allele for FMD (rs9349379-A) was associated with a higher risk of SCAD in all studies. In a meta-analysis of 1,055 SCAD patients and 7,190 controls, the odds ratio (OR) was 1.67 (95% confidence interval [CI]: 1.50 to 1.86) per copy of rs9349379-A. In a subset of 491 SCAD patients, the OR estimate was found to be higher for the association with SCAD in patients without FMD (OR: 1.89; 95% CI: 1.53 to 2.33) than in SCAD cases with FMD (OR: 1.60; 95% CI: 1.28 to 1.99). There was no effect of genotype on age at first event, P-SCAD, or recurrence. Conclusions: The first genetic risk factor for SCAD was identified in the largest study conducted to date for this condition. This genetic link may contribute to the clinical overlap between SCAD and FMD

    Why are women left at home: are they unwilling to go on international assignments?

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    Increasing numbers of women may be climbing the corporate ladder, but when it comes to sending managers on overseas assignments, women are staying home. Is it that women are not interested in international careers, that for some reason companies are reluctant to send women abroad, or that women in foreign countries experience prejudice that prevents them from being effective on their jobs? Our results, based on an extensive survey of female expatriates and their supervisors, indicate that the key may lie in the significantly different views the women and their supervisors hold on the women's interest in pursuing international assignments and in their expectations concerning the prejudice they are likely to encounter. In short, these parties typically do not openly discuss the issues surrounding this important management decision. In addition to presenting the results of our survey, this article discusses strategies to encourage companies to consider women for international assignments and that women can use to increase their chances of being considered. It also presents suggestions for future research.
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