3 research outputs found
Molecular basis for growth plate abnormalities in a mouse model with schmid metaphyseal chondrodyplasia
- Publication venue
- Publication date
- 01/01/1996
- Field of study
Get PDFThe 7th Pan Pacific Connective Tissue Societies Symposium, Cairns, Queensland, Australia, 28 October-1 November 2007
Are oxidized low-density lipoprotein and C-reactive protein markers of atherosclerosis in nephrotic children?
- Author
- A Ece
- A Ece
- A Orzechowski
- A. Rybi-Szumińska
- A. Wasilewska
- AB Magil
- AG Clark
- AJ Lusis
- AN Baer
- B. Osipiuk-Remża
- BL Lechner
- EL Pavlova
- FC Beer De
- H Nakakura
- H Trachtman
- J Fydryk
- J. Michaluk-Skutnik
- JL Mathew
- K Satoh
- M Imakita
- M Nakhjavani
- M. Zając
- NT El-Melegy
- OP Mishra
- P Holvoet
- PL Luz Da
- R Kamireddy
- R. Fiłonowicz
- RC Rose
- RW Chesney
- S Kinra
- SJ Wang
- SM Marcovina
- T Kawamura
- VJ Savin
- Y Ishigaki
- YC Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full textGenetic studies of body mass index yield new insights for obesity biology
- Author
- Aasarød K
- Abecasis G
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- Wojczynski Mary K.
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- Zemunik T
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- Zhang Weihua
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- Zhao Jing Hua
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
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Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P 20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.</p
