An Approach towards Data Clustering By Using NLP and Annotated Text Categorization

Aim is to develop system for clustering of data into user defines clusters with the help of language processing. The main objective behind this research is to solve the problem of data classification into large dataset to get an efficient system which classifies data not only on basis of the dataset, but also on basis of the property of keyword and specified class. This provides the best optimization and segmentation, which incorporate a priori knowledge of existing dataset. This will help end user to choose the item from the particular data cluster from its previous parches or search from the dataset. This field leads to: event resolution, grammar annotation, information mining, knowledgebase, labeling, question/answer, redundancy reduction, similarity measure, summarization, word sense disambiguation, and word sense induction. Implementation of application of Apriory algorithm on the given data to classify the data into the categories. Bisecting K-Means algorithm and hierarchical clustering used categorizing all objects in single cluster. PDDP is the latest development of SVD-based partitioning techniques. DOI: 10.17762/ijritcc2321-8169.15079

Dynamic changes in biochemical markers of renal function with thyroid status- A study in Indian population

Thyroid dysfunction is known to cause significant changes in glomerular filtration rate. The present cross-sectional study was performed to evaluate the changes in biochemical markers of renal function in hypothyroid subjects before and after treatment. Thyroid function tests (T3, T4 and TSH levels) were assayed in 385 subjects. Based on TSH levels, subjects were classified as euthyroid (n=198), sub-clinical hypothyroid (n=98; TSH 6.1 to 19.9 μIU/ml) and overt hypothyroid (n=89; TSH ≥ 20 μIU/ml, abnormally low T4 levels). Forty-eight hypothyroid patients were re-evaluated after 3 months of thyroxine replacement therapy. Renal function tests were carried out in all subjects and statistically analyzed. Serum creatinine was significantly increased in subclinical and overt hypothyroid groups as compared to euthyroid subjects. Serum creatinine showed a significant negative correlation with T3 &T4 levels in overt group(r = -0.372 and r = - 0.371), whereas a positive correlation was observed with TSH (r=0.283). Uric acid levels were significantly increased in the overt group as compared to euthyroid subjects. Uric acid levels showed a significant negative correlation with T3 levels in the overt group (r= -0.298). After 3 months of thyroxine replacement therapy, creatinine and uric acids levels decreased significantly and were comparable to euthyroid levels. Hypothyroidism leads to reversible changes in renal function

Excitation of emission lines by fluorescence and recombination in IC 418

We predict intensities of lines of CII, NI, NII, OI and OII and compare them with a deep spectroscopic survey of IC 418 to test the effect of excitation of nebular emission lines by continuum fluorescence of starlight. Our calculations use a nebular model and a synthetic spectrum of its central star to take into account excitation of the lines by continuum fluorescence and recombination. The NII spectrum is mostly produced by fluorescence due to the low excitation conditions of the nebula, but many CII and OII lines have more excitation by fluorescence than recombination. In the neutral envelope, the NI permitted lines are excited by fluorescence, and almost all the OI lines are excited by recombination. Electron excitation produces the forbidden optical lines of OI, but continuum fluorescence excites most of the NI forbidden line intensities. Lines excited by fluorescence of light below the Lyman limit thus suggest a new diagnostic to explore the photodissociation region of a nebula.Comment: 2 pages, 4 figures, to appear in proceedings of the IAU Symposium 283: "Planetary Nebulae: An Eye to the Future", Eds.: A. Manchado, L. Stanghellini and D. Schoenberne

Precision abundance analysis of bright HII galaxies

We present high signal-to-noise spectrophotometric observations of seven luminous HII galaxies. The observations have been made with the use of a double-arm spectrograph which provides spectra with a wide wavelength coverage, from 3400 to 10400\AA free of second order effects, of exactly the same region of a given galaxy. These observations are analysed applying a methodology designed to obtain accurate elemental abundances of oxygen, sulphur, nitrogen, neon, argon and iron in the ionized gas. Four electron temperatures and one electron density are derived from the observed forbidden line ratios using the five-level atom approximation. For our best objects errors of 1% in t_e([OIII]), 3% in t_e([OII]) and 5% in t_e([SIII]) are achieved with a resulting accuracy of 7% in total oxygen abundances, O/H. The ionisation structure of the nebulae can be mapped by the theoretical oxygen and sulphur ionic ratios, on the one side, and the corresponding observed emission line ratios, on the other -- the \eta and \eta' plots --. The combination of both is shown to provide a means to test photo-ionisation model sequences currently applied to derive elemental abundances in HII galaxies.Comment: 24 pages, 8 figures, accepted by MNRA

Titin truncating variants affect heart function in disease cohorts and the general population

Titin-truncating variants (TTNtv) commonly cause dilated cardiomyopathy (DCM). TTNtv are also encountered in ~1% of the general population, where they may be silent, perhaps reflecting allelic factors. To better understand TTNtv, we integrated TTN allelic series, cardiac imaging and genomic data in humans and studied rat models with disparate TTNtv. In patients with DCM, TTNtv throughout titin were significantly associated with DCM. Ribosomal profiling in rat showed the translational footprint of premature stop codons in Ttn, TTNtv-position-independent nonsense-mediated degradation of the mutant allele and a signature of perturbed cardiac metabolism. Heart physiology in rats with TTNtv was unremarkable at baseline but became impaired during cardiac stress. In healthy humans, machine-learning-based analysis of high-resolution cardiac imaging showed TTNtv to be associated with eccentric cardiac remodeling. These data show that TTNtv have molecular and physiological effects on the heart across species, with a continuum of expressivity in health and disease

Nanoparticle Network Formation in Nanostructured and Disordered Block Copolymer Matrices

Incorporation of nanoparticles composed of surface-functionalized fumed silica (FS) or native colloidal silica (CS) into a nanostructured block copolymer yields hybrid nanocomposites whose mechanical properties can be tuned by nanoparticle concentration and surface chemistry. In this work, dynamic rheology is used to probe the frequency and thermal responses of nanocomposites composed of a symmetric poly(styrene-b-methyl methacrylate) (SM) diblock copolymer and varying in nanoparticle concentration and surface functionality. At sufficiently high loading levels, FS nanoparticle aggregates establish a load-bearing colloidal network within the copolymer matrix. Transmission electron microscopy images reveal the morphological characteristics of the nanocomposites under these conditions

An integrated ultrasound curriculum (iUSC) for medical students: 4-year experience

A review of the development and implementation of a 4-year medical student integrated ultrasound curriculum is presented. Multiple teaching and assessment modalities are discussed as well as results from testing and student surveys. Lessons learned while establishing the curriculum are summarized. It is concluded that ultrasound is a well received, valuable teaching tool across all 4 years of medical school, and students learn ultrasound well, and they feel their ultrasound experience enhances their medical education