Spatially Resolved Spitzer-IRS Spectroscopy of the Central Region of M82

We present high spatial resolution (~ 35 parsec) 5-38 um spectra of the central region of M82, taken with the Spitzer Infrared Spectrograph. From these spectra we determined the fluxes and equivalent widths of key diagnostic features, such as the [NeII]12.8um, [NeIII]15.5um, and H_2 S(1)17.03um lines, and the broad mid-IR polycyclic aromatic hydrocarbon (PAH) emission features in six representative regions and analysed the spatial distribution of these lines and their ratios across the central region. We find a good correlation of the dust extinction with the CO 1-0 emission. The PAH emission follows closely the ionization structure along the galactic disk. The observed variations of the diagnostic PAH ratios across M82 can be explained by extinction effects, within systematic uncertainties. The 16-18um PAH complex is very prominent, and its equivalent width is enhanced outwards from the galactic plane. We interpret this as a consequence of the variation of the UV radiation field. The EWs of the 11.3um PAH feature and the H_2 S(1) line correlate closely, and we conclude that shocks in the outflow regions have no measurable influence on the H_2 emission. The [NeIII]/[NeII] ratio is on average low at ~0.18, and shows little variations across the plane, indicating that the dominant stellar population is evolved (5 - 6 Myr) and well distributed. There is a slight increase of the ratio with distance from the galactic plane of M82 which we attribute to a decrease in gas density. Our observations indicate that the star formation rate has decreased significantly in the last 5 Myr. The quantities of dust and molecular gas in the central area of the galaxy argue against starvation and for negative feedback processes, observable through the strong extra-planar outflows.Comment: 15 pages, 12 figures, 3 tables, ApJ, emulateap

A Spitzer high resolution mid-infrared spectral atlas of starburst galaxies

We present an atlas of Spitzer/IRS high resolution (R~600) 10-37um spectra for 24 well known starburst galaxies. The spectra are dominated by fine-structure lines, molecular hydrogen lines, and emission bands of polycyclic aromatic hydrocarbons. Six out of the eight objects with a known AGN component show emission of the high excitation [NeV] line. This line is also seen in one other object (NGC4194) with, a priori, no known AGN component. In addition to strong polycyclic aromatic hydrocarbon emission features in this wavelength range (11.3, 12.7, 16.4um), the spectra reveal other weak hydrocarbon features at 10.6, 13.5, 14.2um, and a previously unreported emission feature at 10.75um. An unidentified absorption feature at 13.7um is detected in many of the starbursts. We use the fine-structure lines to derive the abundance of neon and sulfur for 14 objects where the HI 7-6 line is detected. We further use the molecular hydrogen lines to sample the properties of the warm molecular gas. Several basic diagrams characterizing the properties of the sample are also shown. We have combined the spectra of all the pure starburst objects to create a high S/N template, which is available to the community.Comment: 25 pages (emulate apj), 6 tables, 14 figures, Accepted for publication in ApJ

Lack of PAH emission toward low-mass embedded young stellar objects

PAHs have been detected toward molecular clouds and some young stars with disks, but have not yet been associated with embedded young stars. We present a sensitive mid-IR spectroscopic survey of PAH features toward a sample of low-mass embedded YSOs. The aim is to put constraints on the PAH abundance in the embedded phase of star formation using radiative transfer modeling. VLT-ISAAC L-band spectra for 39 sources and Spitzer IRS spectra for 53 sources are presented. Line intensities are compared to recent surveys of Herbig Ae/Be and T Tauri stars. The radiative transfer codes RADMC and RADICAL are used to model the PAH emission from embedded YSOs consisting of a PMS star with a circumstellar disk embedded in an envelope. The dependence of the PAH feature on PAH abundance, stellar radiation field, inclination and the extinction by the surrounding envelope is studied. The 3.3 micron PAH feature is undetected for the majority of the sample (97%), with typical upper limits of 5E-16 W/m^2. Compact 11.2 micron PAH emission is seen directly towards 1 out of the 53 Spitzer Short-High spectra, for a source that is borderline embedded. For all 12 sources with both VLT and Spitzer spectra, no PAH features are detected in either. In total, PAH features are detected toward at most 1 out of 63 (candidate) embedded protostars (<~ 2%), even lower than observed for class II T Tauri stars with disks (11-14%). Assuming typical class I stellar and envelope parameters, the absence of PAHs emission is most likely explained by the absence of emitting carriers through a PAH abundance at least an order of magnitude lower than in molecular clouds but similar to that found in disks. Thus, most PAHs likely enter the protoplanetary disks frozen out in icy layers on dust grains and/or in coagulated form.Comment: 13 pages, 9 figures, accepted for publication in A&

The Mid-IR Properties of Starburst Galaxies from Spitzer-IRS Spectroscopy

We present 5-38um mid-infrared spectra at a spectral resolution of R~65-130 of a large sample of 22 starburst nuclei taken with the Infrared Spectrograph IRS on board the Spitzer Space Telescope. The spectra show a vast range in starburst SEDs. The silicate absorption ranges from essentially no absorption to heavily obscured systems with an optical depth of tau(9.8um)~5. The spectral slopes can be used to discriminate between starburst and AGN powered sources. The monochromatic continuum fluxes at 15um and 30um enable a remarkably accurate estimate of the total infrared luminosity of the starburst. We find that the PAH equivalent width is independent of the total starburst luminosity L_IR as both continuum and PAH feature scale proportionally. However, the luminosity of the 6.2um feature scales with L_IR and can be used to approximate the total infrared luminosity of the starburst. Although our starburst sample covers about a factor of ten difference in the [NeIII]/[NeII] ratio, we found no systematic correlation between the radiation field hardness and the PAH equivalent width or the 7.7um/11.3um PAH ratio. These results are based on spatially integrated diagnostics over an entire starburst region, and local variations may be ``averaged out''. It is presumably due to this effect that unresolved starburst nuclei with significantly different global properties appear spectrally as rather similar members of one class of objects.Comment: 22 pages, accepted for publication in ApJ, a high-resolution version is available from http://www.strw.leidenuniv.nl/~brandl/IRS_starbursts.pd

Stromal Vascular Fraction Transplantation as an Alternative Therapy for Ischemic Heart Failure: Anti-inflammatory Role

<p>Abstract</p> <p>Background</p> <p>The aims of this study were: (1) to show the feasibility of using adipose-derived stromal vascular fraction (SVF) as an alternative to bone marrow mono nuclear cell (BM-MNC) for cell transplantation into chronic ischemic myocardium; and (2) to explore underlying mechanisms with focus on anti-inflammation role of engrafted SVF and BM-MNC post chronic myocardial infarction (MI) against left ventricular (LV) remodelling and cardiac dysfunction.</p> <p>Methods</p> <p>Four weeks after left anterior descending coronary artery ligation, 32 Male Lewis rats with moderate MI were divided into 3 groups. SVF group (n = 12) had SVF cell transplantation (6 × 10⁶cells). BM-MNC group (n = 12) received BM-MNCs (6 × 10⁶) and the control (n = 10) had culture medium. At 4 weeks, after the final echocardiography, histological sections were stained with Styrus red and immunohistochemical staining was performed for α-smooth muscle actin, von Willebrand factor, CD3, CD8 and CD20.</p> <p>Results</p> <p>At 4 weeks, in SVF and BM-MNC groups, LV diastolic dimension and LV systolic dimension were smaller and fractional shortening was increased in echocardiography, compared to control group. Histology revealed highest vascular density, CD3+ and CD20+ cells in SVF transplanted group. SVF transplantation decreased myocardial mRNA expression of inflammatory cytokines TNF-α, IL-6, MMP-1, TIMP-1 and inhibited collagen deposition.</p> <p>Conclusions</p> <p>Transplantation of adipose derived SVF cells might be a useful therapeutic option for angiogenesis in chronic ischemic heart disease. Anti-inflammation role for SVF and BM transplantation might partly benefit for the cardioprotective effect for chronic ischemic myocardium.</p

PAH chemistry and IR emission from circumstellar disks

Aims. The chemistry of, and infrared (IR) emission from, polycyclic aromatic hydrocarbons (PAHs) in disks around Herbig Ae/Be and T Tauri stars are investigated. The equilibrium distribution of the PAHs over all accessible charge/hydrogenation states depends on the size and shape of the PAHs and on the physical properties of the star and surrounding disk. Methods. A chemistry model is created to calculate this equilibrium distribution. Destruction of PAHs by ultraviolet (UV) photons, possibly in multi-photon absorption events, is taken into account. The chemistry model is coupled to a radiative transfer code to provide the physical parameters and to combine the PAH emission with the spectral energy distribution (SED) from the star+disk system. Results. Normally hydrogenated PAHs in Herbig Ae/Be disks account for most of the observed PAH emission, with neutral and positively ionized species contributing in roughly equal amounts. Close to the midplane, the PAHs are more strongly hydrogenated and negatively ionized, but these species do not contribute to the overall emission because of the low UV/optical flux deep inside the disk. PAHs of 50 carbon atoms are destroyed out to 100 AU in the disk's surface layer, and the resulting spatial extent of the emission does not agree well with observations. Rather, PAHs of about 100 carbon atoms or more are predicted to cause most of the observed emission. The emission is extended on a scale similar to that of the size of the disk. Furthermore, the emission from T Tauri disks is much weaker and concentrated more towards the central star than that from Herbig Ae/Be disks. Positively ionized PAHs are predicted to be largely absent in T Tauri disks because of the weaker radiation field.Comment: 13 pages, 8 figures, accepted for publication in A&

Spitzer-IRS spectra of disks around T Tauri stars II. PAH emission features

Aims: We search for PAH features towards T Tauri stars and compare them with surveys of Herbig Ae/Be stars. The presence and strength of the PAH features are interpreted with disk radiative transfer models exploring the PAH feature dependence on the incident UV radiation, PAH abundance and disk parameters. Methods: Spitzer Space Telescope 5-35 micron spectra of 54 pre-main sequence stars with disks were obtained, consisting of 38 T Tauri, 7 Herbig Ae/Be and 9 stars with unknown spectral type. Results: Compact PAH emission is detected towards at least 8 sources of which 5 are Herbig Ae/Be stars. The 11.2 micron PAH feature is detected in all of these sources, as is the 6.2 micron PAH feature where short wavelength data are available. However, the 7.7 and 8.6 micron features appear strongly in only 1 of these 4 sources. PAH emission is observed towards at least 3 T Tauri stars (8% detection rate). The lowest mass source with PAHs in our sample is T Cha (G8). All 4 sources in our sample with evidence for dust holes in their inner disk show PAH emission, increasing the feature/continuum ratio. Typical 11.2 micron line intensities are an order of magnitude lower than those observed for the more massive Herbig Ae/Be stars. Measured line fluxes indicate PAH abundances that are factors of 10-100 lower than standard interstellar values. Conversely, PAH features from disks exposed to stars with Teff<=4200K without enhanced UV are predicted to be below the current detection limit, even for high PAH abundances. Disk modeling shows that the 6.2 and 11.2 micron features are the best PAH tracers for T Tauri stars, whereas the 7.7 and 8.6 micron bands have low feature over continuum ratios due to the strongly rising silicate emission.Comment: 20 pages, 15 figures, accepted for publication in A&