Numerical modelling of masonry infill walls in existing steel frames

It is now widely recognised that masonry infill plays an essential role in the seismic behaviour of existing steel buildings; however, there is still a lack of clear guidance on the modelling of masonry infill in the current Eurocode 8-Part 3. Several methods for the numerical modelling of masonry infills have been proposed in literature over the past few decades, which either adopt a detailed approach (micro-model) or a simplified approach (macromodel). In the former case, bricks are individually modelled, taking into account the brickmortar cohesive interface, which is able to provide detailed insights of the behaviour of masonry infills and the frame-wall interaction but usually at a high computational cost. On the other hand, a simplified model can be easily built within finite element software, most of which replace the infill wall panel with one or more equivalent struts in the diagonal direction. It has been demonstrated that the strut models can simulate RC infilled structures’ global response with acceptable accuracy; however, there are still no adequate recommendations for their modelling within steel frames. Besides, these models are generally incapable of capturing the interactions between the infills and the frame members. To this end, the present paper numerically investigates an Abaqus macro-model of the infilled steel frame, which was experimentally tested as part of the recent SERA HITFRAMES project. The preliminary re-sults shows that the different detailing of steel frames could lead to different damage patterns in the infill walls when compared to RC frames. In particular, instead of a single diagonal strut, at most three struts were observed in this study. The results also suggested that the number and geometry of struts could change with increasing displacement demands, hence it might not be appropriate to use the same strut model for infill walls on different floors

Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis

Background: The link between reproductive life history and incidence of ovarian tumors is well known. Periods of reduced ovulations may confer protection against ovarian cancer. Using phenotypic data available for mouse, a possible association between the ovarian transcriptome, reproductive records and spontaneous ovarian tumor rates was investigated in four mouse inbred strains. NIA15k-DNA microarrays were employed to obtain expression profiles of BalbC, C57BL6, FVB and SWR adult ovaries.Results: Linear regression analysis with multiple-test control (adjusted p ≤ 0.05) resulted in ovarian tumor frequency (OTF) and number of litters (NL) as the top-correlated among five tested phenotypes. Moreover, nearly one-hundred genes were coincident between these two traits and were decomposed in 76 OTF(-) NL(+) and 20 OTF(+) NL(-) genes, where the plus/minus signs indicate the direction of correlation. Enriched functional categories were RNA-binding/mRNA-processing and protein folding in the OT

Preliminary numerical analysis of the seismic response of steel frames with masonry infills retrofitted by buckling-restrained braces

Existing steel moment-resisting frames in several seismic regions worldwide are often characterised by high vulnerability to earthquakes due to insufficient local and/or global ductility. Nowadays, it is of paramount importance to assess their response under strong motions and provide cost-effective retrofitting strategies. Amongst others, the seismic behaviour of these frames is often strongly affected by the presence of masonry infills which, from one side, if adequately distributed, beneficially contribute to the seismic resistance of the structure providing stiffness and strength to the frame, from the other side often experience a brittle behaviour and are very vulnerable to seismic actions. To this end, the H2020-INFRAIA-SERA project HITFRAMES (i.e., HybrId Testing of an Existing Steel Frame with Infills under Multiple EarthquakeS) experimentally evaluated a case study building representative of non-seismically designed European steel frames with masonry infills and investigated a possible retrofit strategy. This paper takes advantage of the experimental results of the HITFRAMES project to calibrate numerical models in OpenSees of a case study building which is analysed as bare, infilled and retrofitted frame with buckling-restrained braces (BRBs). The impact of masonry infills and BRB-retrofit is investigated by comparing the response of models with different configurations. The numerical results provide some insights on the ability of BRB-retrofit option in protecting not only the steel frames from experiencing critical damage during earthquakes but also the masonry infills and on the importance of using appropriate models for the masonry infills in the assessment procedures

Nitrofluorene derivatives trapped within MWCNTs for electrocatalysis of NADH: Substituent effects on π-π stacking interaction strength

We describe nanostructured electrode platforms composed of multiwalled carbon nanotube/glassy carbon electrodes (MWCNT/GCEs) with entrapped nitroaromatic compounds such as 2-nitrofluorene (2-NF), 2-nitro-9- fluorenone (2-NFN), 2,7-dinitrofluorene (2,7-NF) and 2,7-dinitro-9-fluorenone (2,7-NFN). All of the above ni- troaromatic compounds were tested as precursors for the production of redox mediator couples useful for NADH electrocatalysis. In this communication, we reveal the effect of the substituents on both the π-π stacking interaction strength and the electrocatalysis of NADH. The results show that the nitro group plays a triple role: it acts as a precursor of the mediator redox couple for NADH electrocatalysis; it increases the π-π stacking interaction with the electrode; and it acts as an electron acceptor substituent that promotes the electrocatalysis of NADHWe thank FONDECYT Grant 1170054 and 1210899 for financial supportDepartamento de Ingeniería Química, Química Física y Ciencias de los Materiale

Effect of phenols on the potentiometric response of a nitrate-ion-selective electrode

Abstract The effect of phenols containing different electron-withdrawing substituents on the potentiometric responses of several liquid PVC membranes containing the complex trioctylmethylammonium-nitrate, TOMA + NO − 3 , is analyzed. The results make it possible to separate these phenols into two groups; those phenols containing electron-releasing groups, which produce almost Nernstian slopes, and those containing electron-withdrawing substituents, which generate sub-Nernstian slopes. The highly negative standard free energy of transfer of the aryl phenolic group from water to a cationic polar head suggests that these phenols are mainly located in the membrane phase associated with TOMA + via a cation-π interaction. It seems that the strength of this interaction, and hence of the nitrate dissociation, is affected by the presence of phenols in an extension which correlates well with the kind of phenol present in these membranes and, consequently, with the type of their potentiometric responses

Nuevos enfoques de valoración de empresas. Aplicación de la metodología de opciones a una empresa de transporte de carga chilena

Diversos estudios asimilan las acciones de una empresa como una opción de compra sobre los activos de la compañía. Basado en aquello, en este estudio determinamos el valor de una empresa de transporte de carga chilena mediante la aplicación de la metodología de opciones. Las opciones consideran el aporte de la flexibilidad en la evaluación por lo que se ajusta a escenarios inciertos. Asimismo, se incorporó el valor de la incertidumbre mediante movimiento geométrico browniano y simulación de Montecarlo. Preliminarmente y para efectos de comparación, se valoró la empresa a través de Flujos de Caja Descontados. Se pudo establecer que la metodología de opciones usada para valorar empresas genera un valor adicional debido al impacto del riesgo sobre el valor de la acción.Several studies consider as the shares of a company as a call option over the assets. Based on that, in this study we determine the value of a Chilean freight company by application of Options Methodology. The options considered the contribution of the flexibility in the assessment so that it fits uncertain environments. Further the uncertainly value was incorporated by Geometric Brownian Motion and Montecarlo simulation. Preliminary and for comparison, the company was valued by Discounted Cash Flow (DCF). It was established that the Options Methodology used to assess companies generates additional value due to the risk impact over the share’s value

The influence of glacial melt and retreat on the nutritional condition of the bivalve Nuculana inaequisculpta (Protobranchia: Nuculanidae) in the West Antarctic Peninsula

Due to climate change, numerous ice bodies have been lost in the West Antarctic Peninsula (WAP). As a consequence, deglaciation is expected to impact the marine environment and its biota at physiological and ecosystem levels. Nuculana inaequisculpta is a marine bivalve widely distributed around Antarctica that plays an important role for ecosystem functioning. Considering that N. inaequisculpta inhabits coastal areas under effect of glacial melt and retreat, impacts on its nutritional condition are expected due to alterations on its physiology and food availability. To test this hypothesis, biochemical composition (lipids, proteins, and fatty acids) and energy content were measured in individuals of N. inaequisculpta collected in a fjord at different distances to the retreating glacier in the WAP. Oceanographic parameters of the top and bottom-water layers (temperature, salinity, dissolved oxygen, and chlorophyll-a) were measured to investigate how the environment changes along the fjord. Results showed that surface oceanographic parameters displayed a lower temperature and dissolved oxygen, but a higher salinity and chlorophyll-a content at nearest compared to farthest sites to the glacier. In contrast, a lower temperature and chlorophyll-a, and a higher salinity and dissolved oxygen was measured in the bottom-water layer toward the glacier. N. inaequisculpta had a higher amount of lipids (17.42 ± 3.24 vs. 12.16 ± 3.46%), protein (24.34 ± 6.12 vs. 21.05 ± 2.46%) and energy content (50.57 ± 6.97 J vs. 39.14 ± 5.80 J) in the farthest compared to the nearest site to the glacier. No differences were found in total fatty acids among all sites. It seems likely that lower individual fitness related to proximity to the glacier would not be related to nutritional quality of sediment food, but rather to food quantity

Temporal evolution of a driven optomechanical system in the strong coupling regime

We obtain a time-evolution operator for a forced optomechanical quantum system using Lie algebraic methods when the normalized coupling between the electromagnetic field and a mechanical oscillator, $G/\omega_m$, is not negligible compared to one. Due to the forcing term, the interaction picture Hamiltonian contains the number operator in the exponents, and in order to deal with it, we approximate these exponentials by their average values taken between initial coherent states. Our approximation is justified when we compare our results with the numerical solution of the number of photons, phonons, Mandel parameter, and the Wigner function, showing an excellent agreement.Comment: 21 pages, 11 figure

Assessment of existing steel frames: Numerical study, pseudo-dynamic testing and influence of masonry infills

Most of existing steel multi-storey frames in Europe have been designed before the introduction of modern seismic design provisions, hence they often exhibit low performance under earthquake loads due to their low lateral resistance and energy dissipation capacity. In addition, such structures often include rigid and brittle masonry infill walls that highly influence their lateral response and distribution of damage pattern. However, current procedures for the assessment of existing steel buildings in Europe, included in the Eurocode 8 – Part 3 (EC8–3), do not provide adequate guidance for the assessment of ‘weak’ steel frame with masonry infill walls. Moreover, most of available modelling approaches of masonry infills formerly developed for reinforced concrete (RC) structures do not properly represent the behaviour of infill walls in steel frames. An improved numerical has to be provided to satisfactorily mimic infill walls' behaviour in steel moment frames. To this end, an experimental and theoretical study was carried out within the framework of HITFRAMES (i.e., HybrId Testing of an Existing Steel Frame with Infills under Multiple EarthquakeS) SERA project. This paper firstly presents the limitations of current EC8–3 by conducting a code-based assessment on a case study steel moment frame using pushover analysis. Three different single strut models, widely used for simulating the presence of masonry infills in RC structures, are considered for the numerical analyses. The paper also presents the results of pseudo-dynamic (PsD) tests performed on a large-scale 3D steel frame with masonry infills. The capability of the different masonry infill models is successively evaluated by comparisons between numerical and experimental results. On the basis of the obtained results, recommendations on how to potentially improve the single strut model for masonry infills surrounded by steel frames are also provided

An integrated biochemical system for nitrate assimilation and nitric oxide detoxification in Bradyrhizobium japonicum

Rhizobia are recognized to establish N(2)-fixing symbiotic interactions with legume plants. Bradyrhizobium japonicum, the symbiont of soybeans, can denitrify and grow under free-living conditions with nitrate (NO(3)(−)) or nitrite (NO(2)(−)) as sole nitrogen source. Unlike related bacteria that assimilate NO(3)(−), genes encoding the assimilatory NO(3)(−) reductase (nasC) and NO(2)(−) reductase (nirA) in B. japonicum are located at distinct chromosomal loci. The nasC gene is located with genes encoding an ABC-type NO(3)(−) transporter, a major facilitator family NO(3)(−)/NO(2)(−) transporter (NarK), flavoprotein (Flp) and single-domain haemoglobin (termed Bjgb). However, nirA clusters with genes for a NO(3)(−)/NO(2)(−)-responsive regulator (NasS-NasT). In the present study, we demonstrate NasC and NirA are both key for NO(3)(−) assimilation and that growth with NO(3)(−), but not NO(2)(−) requires flp, implying Flp may function as electron donor to NasC. In addition, bjgb and flp encode a nitric oxide (NO) detoxification system that functions to mitigate cytotoxic NO formed as a by-product of NO(3)(−) assimilation. Additional experiments reveal NasT is required for NO(3)(−)-responsive expression of the narK-bjgb-flp-nasC transcriptional unit and the nirA gene and that NasS is also involved in the regulatory control of this novel bipartite assimilatory NO(3)(−)/NO(2)(−) reductase pathway