Towards a consistent set of parameters for the definition of a new GRS

Short description of the activities of the GGOS Working Group and some ideas about its continuation

Assembling and Verification of a Fitness Test Battery for the Recruitment of the Swiss Army and Nation-Wide Use

The aim of this study was to assess the reliability, validity and feasibility of selected physical performance tests, to compile a new fi tness test battery based on these results and to obtain standard values for young men. 79 men (20.3 ± 1.1 y) performed the tests for the reliability part, while 60 men (20.3 ± 1.1 y) completed the tests for the validity part of the study. Feasibility was confi rmed by 25 sport experts who conducted the test battery among 1704 men (19.5 ± 1.0 y). For standard values, the data of 12 862 men (19.9 ± 1.0 y) were collected. Based on the reliability and validity data, the following 5 tests were selected for the fi tness-test battery: 1) progressive endurance run, 2) seated 2-kg-shot put, 3) standing long jump, 4) trunk muscle strength test and 5) 1-leg standing test. The reliability and validity of the selected performance tests were suffi cient to very good (r = 0.50–0.90 and r = 0.64–0.91, respectively). The suggested fi tness-test battery can be applied among large groups

Selbstbestimmung in der griechischen Antike

Haben die Griechen die Politik erfunden? Die Frage wird in der Forschung seit langem kontrovers beurteilt. Unklar ist bereits der genaue Sinn der Frage. Geht es wirklich um die Erfindung der Politik, oder geht es darum, eine despotische von einer liberalen Politik zu unterscheiden? Die Frage ist heute wiederum aktuell, weil das Problem des angeblichen oder tatsächlichen Eurozentrismus auftaucht. Diesen Aspekt werde ich hier nicht erörtern. Ich möchte in einem ersten Schritt die Positionen von Autorinnen und Autoren diskutieren, welche die athenische Polis als Ort von Gleichheit, Freiheit, Gewaltlosigkeit, Agon und Exzellenz verstehen. In einem zweiten Schritt soll die Gegenseite zu Wort kommen, Autorinnen und Autoren welche die Stasis, die Permanenz von Gewalt und Bürgerkrieg in den Vordergrund rücken. Die Frage, inwiefern in der griechischen Antike von kollektiver und/oder individueller Autonomie die Rede sein kann, wird im Artikel immer wieder von neuem gestellt

Ausgewählte philosophische Schriften

Bei der Publikation handelt es sich um den zweiten von zwei Bänden der Edition ausgewählter fachphilosophischer Schriften der Genfer Philosophin Jeanne Hersch (1910-2000). Ziel der Edition ist es, vergriffene oder nur schwer zugängliche Schriften der bedeutendsten Schweizer Philosophin einem breiteren Publikum zugänglich zu machen. Dazu wurden die ausgewählten Texte von Hersch von den Herausgebern eingeleitet und mit einem ausführlichen wissenschaftlichen Kommentar versehen. Die Schriften erscheinen in deutscher Sprache, wobei entweder auf bereits vorliegende Übersetzungen zurückgegriffen wurde oder Übersetzungen eigens für die Edition angefertigt wurden. Der zweite Band der Edition enthält Texte von Hersch zur politischen Philosophie. Er umfasst als Hauptwerk das Buch "Die Ideologien und die Wirklichkeit" sowie eine Auswahl von Aufsätzen. Damit sind Herschs philosophische Stellungnahmen zur politischen und ideologischen Situation der Nachkriegszeit, insbesondere ihre Kritik totalitärer Ideologien, ihre Analysen des politischen Handelns und der Ontologie von Macht sowie ihre Bemühungen um eine philosophische Begründung und eine Klärung der Bedeutung der Menschenrechte repräsentiert

CCM – IAG Strategy for Metrology in Absolute Gravimetry: Role of CCM and IAG

The President of the Consultative Committee for Mass and related quantities (CCM) and the President of the International Association of Geodesy (IAG) Commission 2 «Gravity Field» met on March 21, 2013 with the objective to better coordinate the work at the level of both organizations. It was decided to prepare a common strategic document to be used by their respective Working Groups (WG), Sub-commission (SC) and Joint Working Groups (JWG) to clarify future activities and to develop an action plan.The main objective is to define and to harmonize the activities in order to ensure traceability to the SI for gravity measurements at the highest level for metrology and geodesy with-in the framework of the CIPM Mutual Recognition Arrangement (CIPM MRA

Overdeepenings in the Swiss plateau: U-shaped geometries underlain by inner gorges

We investigated the mechanisms leading to the formation of tunnel valleys in the Swiss foreland near Bern. We proceeded through producing 3D maps of the bedrock topography based on drillhole information and a new gravimetric survey combined with modelling. In this context, the combination of information about the densities of the sedimentary fill and of the bedrock, together with published borehole data and the results of gravity surveys along 11 profiles across the valleys, served as input for the application of our 3D gravity modelling software referred to as PRISMA. This ultimately allowed us to model the gravity effect of the Quaternary fill of the overdeepenings and to produce cross-sectional geometries of these troughs. The results show that 2–3 km upstream of the city of Bern, the overdeepenings are approximately 3 km wide. They are characterized by steep to oversteepened lateral flanks and a wide flat base, which we consider as a U-shaped cross-sectional geometry. There, the maximum residual gravity anomaly ranges between − 3 to − 4 mGal for the Aare valley, which is the main overdeepening of the region. Modelling shows that this corresponds to a depression, which reaches a depth of c. 300 m a.s.l. Farther downstream approaching Bern, the erosional trough narrows by c. 1 km, and the base gets shallower by c. 100 m as revealed by drillings. This is supported by the results of our gravity surveys, which disclose a lower maximum gravity effect of c. − 0.8 to − 1.3 mGal. Interestingly, in the Bern city area, these shallow troughs with maximum gravity anomalies ranging from − 1.4 to − 1.8 mGal are underlain by one or multiple inner gorges, which are at least 100 m deep (based on drilling information) and only a few tens of meters wide (disclosed by gravity modelling). At the downstream end of the Bern area, we observe that the trough widens from 2 km at the northern border of Bern to c. 4 km approximately 2 km farther downstream, while the bottom still reaches c. 300 to 200 m a.s.l. Our gravity survey implies that this change is associated with an increase in the maximum residual anomaly, reaching values of − 2.5 mGal. Interestingly, the overdeepening’s cross-sectional geometry in this area has steeply dipping flanks converging to a narrow base, which we consider as V-shaped. We attribute this shape to erosion by water either underneath or at the snout of a glacier, forming a gorge. This narrow bedrock depression was subsequently widened by glacial carving. In this context, strong glacial erosion upstream of the Bern area appears to have overprinted these traces. In contrast, beneath the city of Bern and farther downstream these V-shaped features have been preserved. Available chronological data suggest that the formation of this gorge occurred prior to MIS 8 and possibly during the aftermath of one of the largest glaciations when large fluxes of meltwater resulted in the fluvial carving into the bedrock

Design and clinical evaluation of an image-guided surgical microscope with an integrated tracking system

A new image-guided microscope system using augmented reality image overlays has been developed. With this system, CT cut-views and segmented objects such as tumors that have been previously extracted from preoperative tomographic images can be directly displayed as augmented reality overlays on the microscope image. The novelty of this design stems from the inclusion of a precise mini-tracker directly on the microscope. This device, which is rigidly mounted to the microscope, is used to track the movements of surgical tools and the patient. In addition to an accuracy gain, this setup offers improved ergonomics since it is much easier for the surgeon to keep an unobstructed line of sight to tracked objects. We describe the components of the system: microscope calibration, image registration, tracker assembly and registration, tool tracking, and augmented reality display. The accuracy of the system has been measured by validation on plastic skulls and cadaver heads, obtaining an overlay error of 0.7mm. In addition, a numerical simulation of the system has been done in order to complement the accuracy study, showing that the integration of the tracker onto the microscope could lead to an improvement of the accuracy to the order of 0.5mm. Finally, we describe our clinical experience using the system in the operation room, where three operations have been performed to dat

Sinus node disease and arrhythmias in the long-term follow-up of former professional cyclists

Aims Significant brady- and tachyarrhythmias may occur in active endurance athletes. It is controversial whether these arrhythmias do persist after cessation of competitive endurance training. Methods and results Among all 134 former Swiss professional cyclists [hereafter, former athletes (FAs)] participating at least once in the professional bicycle race Tour de Suisse in 1955-1975, 62 (46%) were recruited for the study. The control group consisted of 62 male golfers matched for age, weight, hypertension, and cardiac medication. All participants were screened with history, clinical and echocardiographic examination, ECG, and 24 h ECG. The time for the last bicycle race of FAs was 38 ± 6 years. The mean age at examination was 66 ± 6 years in controls and 66 ± 7 years in FAs (P = 0.47). The percentage of study participants with >4 h current cardiovascular training per week was identical. QRS duration (102 ± 20 vs. 95 ± 13 ms, P = 0.03) and corrected QTc interval (416 ± 27 vs. 404 ± 18, P = 0.004) were longer in FAs. There was no significant difference in the number of isolated atrial or ventricular premature complexes, or supraventricular tachycardias in the 24 h ECG; however, ventricular tachycardias tended to occur more often in FAs than in controls (15 vs. 3%, P = 0.05). The average heart rate was lower in FAs (66 ± 9 vs. 70 ± 8 b.p.m.) (P = 0.004). Paroxysmal or persistent atrial fibrillation or flutter was reported more often in FAs (P = 0.028). Sinus node disease (SND), defined as bradycardia of 2.5 s (6 vs. 0%), was more common in FA (16%) than in controls (2%, P = 0.006). Observed survival of all FAs was not different from the expected. Conclusions Among FAs, SND occurred significantly more often compared with age-matched controls, and there is trend towards more frequent ventricular tachycardias. Further studies have to evaluate prevention of arrhythmias with extreme endurance training, the necessity of regular follow-up of heart rhythm, and management of arrhythmias in former competitive endurance athlete

GGOS Bureau of Products and Standards: Description and Promotion of Geodetic Products

The Bureau of Products and Standards (BPS) is a key component of the Global Geodetic Observing System (GGOS) of the International Association of Geodesy (IAG). It supports GGOS in its goal to provide consistent geodetic products needed to monitor, map, and understand changes in the Earth’s shape, rotation, and gravity field. In its present structure, the two Committees "Earth System Modeling" and "Essential Geodetic Variables" as well as the Working Group "Towards a consistent set of parameters for the definition of a new Geodetic Reference System (GRS)" are associated to the BPS. This paper presents the structure and role of the BPS and it highlights some of the recent activities. A major focus is on the classification and description of geodetic products and their representation at the renewed GGOS website (www.ggos.org). This website serves as an "entrance door" to geodetic products to satisfy different user needs and communities (e.g., geodesists, geophysicists, other geosciences and further customers) in order to make geodesy more visible to other disciplines and to society

Time to treatment with bridging intravenous alteplase before endovascular treatment:subanalysis of the randomized controlled SWIFT-DIRECT trial.

BACKGROUND We hypothesized that treatment delays might be an effect modifier regarding risks and benefits of intravenous thrombolysis (IVT) before mechanical thrombectomy (MT). METHODS We used the dataset of the SWIFT-DIRECT trial, which randomized 408 patients to IVT+MT or MT alone. Potential interactions between assignment to IVT+MT and expected time from onset-to-needle (OTN) as well as expected time from door-to-needle (DTN) were included in regression models. The primary outcome was functional independence (modified Rankin Scale (mRS) 0-2) at 3 months. Secondary outcomes included mRS shift, mortality, recanalization rates, and (symptomatic) intracranial hemorrhage at 24 hours. RESULTS We included 408 patients (IVT+MT 207, MT 201, median age 72 years (IQR 64-81), 209 (51.2%) female). The expected median OTN and DTN were 142 min and 54 min in the IVT+MT group and 129 min and 51 min in the MT alone group. Overall, there was no significant interaction between OTN and bridging IVT assignment regarding either the functional (adjusted OR (aOR) 0.76, 95% CI 0.45 to 1.30) and safety outcomes or the recanalization rates. Analysis of in-hospital delays showed no significant interaction between DTN and bridging IVT assignment regarding the dichotomized functional outcome (aOR 0.48, 95% CI 0.14 to 1.62), but the shift and mortality analyses suggested a greater benefit of IVT when in-hospital delays were short. CONCLUSIONS We found no evidence that the effect of bridging IVT on functional independence is modified by overall or in-hospital treatment delays. Considering its low power, this subgroup analysis could have missed a clinically important effect, and exploratory analysis of secondary clinical outcomes indicated a potentially favorable effect of IVT with shorter in-hospital delays. Heterogeneity of the IVT effect size before MT should be further analyzed in individual patient meta-analysis of comparable trials. TRIAL REGISTRATION NUMBER URL: https://www. CLINICALTRIALS gov ; Unique identifier: NCT03192332