27 research outputs found

    4-Carb­oxy-2-methyl-1H-imidazol-3-ium-5-carboxyl­ate monohydrate

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    In the title compound, C6H6N2O4·H2O, one carboxyl group is deprotonated and one imidazole N atom is protonated. The organic mol­ecule, excluding methyl H atoms, is essentially planar, with an r.m.s. deviation of 0.0156 (1) Å. In the crystal structure, inter­molecular N—H⋯O hydrogen bonds link mol­ecules into chains along the b axis; these chains are further linked via O—H⋯O hydrogen bonds involving the water O atoms and carboxyl O atoms, generating a two-dimensional supra­molecular framework

    2-(2-Hydroxyphenyl)-4,5-dimethyl-1H-imidazol-3-ium acetate monohydrate

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    In the title compound, C11H13N2O+·C2H3O2 −·H2O, the dihedral angle between the benzene ring and the imidazole ring is 7.83 (6)°. In the crystal structure, N—H⋯O and O—H⋯O hydrogen bonds form a two-dimensional network. All the methyl H atoms are disorderd over two sites with equal occupancies

    2-(4-Fluoro­phen­yl)-1-(4-meth­oxy­phen­yl)-4,5-dimethyl-1H-imidazole

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    In the title compound, C18H17FN2O, the imidazole ring makes dihedral angles of 76.46 (7) and 40.68 (7)° with the meth­oxy­phenyl and fluoro­phenyl rings, respectively. The dihedral angle between the two benzene rings is 71.25 (6)°

    Synthesis and antifungal activities of some aryl (3-methyl-benzofuran-2-yl) ketoximes

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    In this study, some aryl (3-methyl-benzofuran-2-yl) ketoximes and their. ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1-NMR, MASS spectroscopy and elemental analyses. Antifungal activities of the compounds were examined and moderate activity was obtained

    Synthesis and antimicrobial activities of some imidazole substituted indoles

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    174-179The compounds 1-substituted 2-(imidazol-1-yl )-3 -(4,5-diarylimidazol-2-yl) indoles 2,1- substituted 2-(imidazol-1-yl)-3-(phenanthro[9, 10-d]imidazol-2-yl)indoles 3 and 1- substituted 2-(imidazol-l-yl)-3-(be nzimidazol-2-yl)indoles 4 have been synthesized from 1-substituted 2-(imidazol-1-yl)-3-formylindole 1. The structural elucidation of the synthesised compounds has been performed by IR, 1H NMR and mass spectroscopic data and elemental analyses. Antimicrobial activities of the compounds are examined and notable antifungal activity is obtained from some of the compounds as expected in comparison with the control agent ketoconazole

    4-(4,5-Diphenyl-1H-imidazol-2-yl)-N,N-dimethylaniline

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    The asymmetric unit of the title compound, C23H21N3, consists of two symmetry-independent and conformationally different molecules [the comparable dihedral angles between the imidazole ring and the three benzene rings being 38.5 (2)/61.5 (3)/3.37 (17) and 45.8 (2)/36.01 (19)/46.94 (17)°]. In the crystal, intermolecular imidazole N—H...N hydrogen-bonding interactions give a one-dimensional chain extending along [101]
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