826 research outputs found

    Inverse problem for wave equation with sources and observations on disjoint sets

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    We consider an inverse problem for a hyperbolic partial differential equation on a compact Riemannian manifold. Assuming that Γ1\Gamma_1 and Γ2\Gamma_2 are two disjoint open subsets of the boundary of the manifold we define the restricted Dirichlet-to-Neumann operator ΛΓ1,Γ2\Lambda_{\Gamma_1,\Gamma_2}. This operator corresponds the boundary measurements when we have smooth sources supported on Γ1\Gamma_1 and the fields produced by these sources are observed on Γ2\Gamma_2. We show that when Γ1\Gamma_1 and Γ2\Gamma_2 are disjoint but their closures intersect at least at one point, then the restricted Dirichlet-to-Neumann operator ΛΓ1,Γ2\Lambda_{\Gamma_1,\Gamma_2} determines the Riemannian manifold and the metric on it up to an isometry. In the Euclidian space, the result yields that an anisotropic wave speed inside a compact body is determined, up to a natural coordinate transformations, by measurements on the boundary of the body even when wave sources are kept away from receivers. Moreover, we show that if we have three arbitrary non-empty open subsets Γ1,Γ2\Gamma_1,\Gamma_2, and Γ3\Gamma_3 of the boundary, then the restricted Dirichlet-to-Neumann operators ΛΓj,Γk\Lambda_{\Gamma_j,\Gamma_k} for 1≤j<k≤31\leq j<k\leq 3 determine the Riemannian manifold to an isometry. Similar result is proven also for the finite-time boundary measurements when the hyperbolic equation satisfies an exact controllability condition

    Dynamics of viscous dissipative gravitational collapse: A full causal approach

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    The Misner and Sharp approach to the study of gravitational collapse is extended to the viscous dissipative case in, both, the streaming out and the diffusion approximations. The dynamical equation is then coupled to causal transport equations for the heat flux, the shear and the bulk viscosity, in the context of Israel--Stewart theory, without excluding the thermodynamics viscous/heat coupling coefficients. The result is compared with previous works where these later coefficients were neglected and viscosity variables were not assumed to satisfy causal transport equations. Prospective applications of this result to some astrophysical scenarios are discussed.Comment: 22 pages Latex. To appear in Int. J. Mod. Phys. D. Typos correcte

    Some analytical models of radiating collapsing spheres

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    We present some analytical solutions to the Einstein equations, describing radiating collapsing spheres in the diffusion approximation. Solutions allow for modeling physical reasonable situations. The temperature is calculated for each solution, using a hyperbolic transport equation, which permits to exhibit the influence of relaxational effects on the dynamics of the system.Comment: 17 pages Late

    Inverse problem by Cauchy data on arbitrary subboundary for system of elliptic equations

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    We consider an inverse problem of determining coefficient matrices in an NN-system of second-order elliptic equations in a bounded two dimensional domain by a set of Cauchy data on arbitrary subboundary. The main result of the article is as follows: If two systems of elliptic operators generate the same set of partial Cauchy data on an arbitrary subboundary, then the coefficient matrices of the first-order and zero-order terms satisfy the prescribed system of first-order partial differential equations. The main result implies the uniqueness of any two coefficient matrices provided that the one remaining matrix among the three coefficient matrices is known

    Fourier, hyperbolic and relativistic heat transfer equations: a comparative analytical study

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    [EN] Parabolic heat equation based on Fourier's theory (FHE), and hyperbolic heat equation (HHE), has been used to mathematically model the temperature distributions of biological tissue during thermal ablation. However, both equations have certain theoretical limitations. The FHE assumes an infinite thermal energy propagation speed, whereas the HHE might possibly be in breach of the second law of thermodynamics. The relativistic heat equation (RHE) is a hyperbolic-like equation, whose theoretical model is based on the theory of relativity and which was designed to overcome these theoretical impediments. In this study, the three heat equations for modelling of thermal ablation of biological tissues (FHE, HHE and RHE) were solved analytically and the temperature distributions compared. We found that RHE temperature values were always lower than those of the FHE, while the HHE values were higher than the FHE, except for the early stages of heating and at points away from the electrode. Although both HHE and RHE are mathematically hyperbolic, peaks were only found in the HHE temperature profiles. The three solutions converged for infinite time or infinite distance from the electrode. The percentage differences between the FHE and the other equations were larger for higher values of thermal relaxation time in HHE.This work received financial support from the Spanish Government (Ministerio de Ciencia e Innovacion, Ref. TEC2011-27133-C02-01).López Molina, JA.; Rivera Ortun, MJ.; Berjano, E. (2014). Fourier, hyperbolic and relativistic heat transfer equations: a comparative analytical study. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. 470:1-16. https://doi.org/10.1098/rspa.2014.0547S11647

    Pore-size dependence of the thermal conductivity of porous silicon : a phonon hydrodynamic approach

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    Phononhydrodynamics is used to analyze the influence of porosity and of pore size on reduction in thermal conductivity in porous silicon, with respect to crystalline silicon. The expressions predict that the thermal conductivity is lower for higher porosity and for smaller pore radius, as a consequence of phononballisticeffects. The theoretical results describe experimental data better than the assumption that they only depend on porosity

    Oscillatory Flow in a Cone-and-Plate Bioreactor

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    Organics in comet 67P – a first comparative analysis of mass spectra from ROSINA–DFMS, COSAC and Ptolemy

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    The ESA Rosetta spacecraft followed comet 67P at a close distance for more than 2 yr. In addition, it deployed the lander Philae on to the surface of the comet. The (surface) composition of the comet is of great interest to understand the origin and evolution of comets. By combining measurements made on the comet itself and in the coma, we probe the nature of this surface material and compare it to remote sensing observations. We compare data from the double focusing mass spectrometer (DFMS) of the ROSINA experiment on ESA's Rosetta mission and previously published data from the two mass spectrometers COSAC (COmetary Sampling And Composition) and Ptolemy on the lander. The mass spectra of all three instruments show very similar patterns of mainly CHO-bearing molecules that sublimate at temperatures of 275 K. The DFMS data also show a great variety of CH-, CHN-, CHS-, CHO2- and CHNO-bearing saturated and unsaturated species. Methyl isocyanate, propanal and glycol aldehyde suggested by the earlier analysis of the measured COSAC spectrum could not be confirmed. The presence of polyoxymethylene in the Ptolemy spectrum was found to be unlikely. However, the signature of the aromatic compound toluene was identified in DFMS and Ptolemy data. Comparison with remote sensing instruments confirms the complex nature of the organics on the surface of 67P, which is much more diverse than anticipated

    Immunoproteasome Overexpression Underlies the Pathogenesis of Thyroid Oncocytes and Primary Hypothyroidism: Studies in Humans and Mice

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    BACKGROUND:Oncocytes of the thyroid gland (Hürthle cells) are found in tumors and autoimmune diseases. They have a unique appearance characterized by abundant granular eosinophilic cytoplasm and hyperchromatic nucleus. Their pathogenesis has remained, thus far, unknown. METHODOLOGY/PRINCIPAL FINDINGS:Using transgenic mice chronically expressing IFNgamma in thyroid gland, we showed changes in the thyroid follicular epithelium reminiscent of the human oncocyte. Transcriptome analysis comparing transgenic to wild type thyrocytes revealed increased levels of immunoproteasome subunits like LMP2 in transgenics, suggesting an important role of the immunoproteasome in oncocyte pathogenesis. Pharmacologic blockade of the proteasome, in fact, ameliorated the oncocytic phenotype. Genetic deletion of LMP2 subunit prevented the development of the oncocytic phenotype and primary hypothyroidism. LMP2 was also found expressed in oncocytes from patients with Hashimoto thyroiditis and Hürthle cell tumors. CONCLUSIONS/SIGNIFICANCE:In summary, we report that oncocytes are the result of an increased immunoproteasome expression secondary to a chronic inflammatory milieu, and suggest LMP2 as a novel therapeutic target for the treatment of oncocytic lesions and autoimmune hypothyroidism
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