Geoscape: Lessons Learned from 15 Years of Geoscience Outreach

Geoscape is the name for a long term geoscience outreach initiative led by staff of the Geological Survey of Canada (GSC) Vancouver office and designed to better connect people to the land they live on. Although largely focused on outreach in British Columbia, the initiative has been active across Canada and supported by a number of different GSC programs. Geoscape products, some 35 in total, include Geoscape, GeoMap, Waterscape, and climate change series posters, as well as geological highway maps and GeoTour booklets. A popular geoscience book and a national climate change poster series were inspired by Geoscape work. Begun in 1994, Geoscape has drawn dozens of Canadian geoscientists and educators into outreach efforts. This paper summarizes the accomplishments of Geoscape and some of the lessons we learned along the way.SOMMAIREGéopanorama est le nom d'une activité géoscientifique de sensibilisation à long terme menée par le personnel du bureau de Vancouver de la Commission géologique du Canada (CGC) visant à créer des liens entre les gens et la terre sur laquelle ils vivent.  Bien que visant largement la sensibilisation en Colombie-Britannique, l’activité a été menée à travers le Canada et soutenue grâce à un certain nombre de programmes différents de la CGC.  Quelques 35 productions de Géopanorama ont déjà été réalisées, dont Géopanorama, GeoMap, Waterscape, une série d’affiches sur le changement climatique, ainsi que des cartes routières géologiques et des livrets touristiques GeoTour.  Un livre géoscientifiques grand public et une série nationale d’affiches sur le changement climatique découlent directement de Géopanorama.  Commencée en 1994, Géopanorama a inspiré les efforts de sensibilisation de dizaines de géoscientifiques et d’éducateurs canadiens.  Le présent article présente un sommaire des réalisations de Géopanorama ainsi que certaines des leçons que nous avons apprises en cours de route

Learning in doing: the social anthropology of innovation in a large UK organisation

In the face of increasingly dynamic market environments, firms are being urged to develop learning and innovation capabilities if they wish to secure competitive advantage and long-term growth. A bank of work written from numerous theoretical perspectives has converged on the view that knowledge underpins the formation of such capabilities. While much of this literature emphasises the importance of cognitive knowledge, a new approach grounded in techniques from social anthropology suggests that learning is a non-cognitive practice, drawing on embodied exploration, everyday sociality, and a communitarian infrastructure of human and non-human actants. This thesis aims to consolidate the current literature on 'possessed' knowledge by clarifying the relationship between cognition and learning, and to advance understanding of innovation practices within firms by examining the role of non-cognitive mechanisms in the development of organisational capabilities. Drawing on a nine-month period of ethnographic research, this thesis describes the on-the-ground processes of learning and innovation within the marketing department of a large UK organisation. This evidence is used to investigate critically the theoretical claims regarding the role of both cognitive and non-cognitive forms of knowledge. Based on the empirical findings, three interrelated arguments are proposed: the design and governance of strategic learning devices involve non-cognitive practices; informal mechanisms of learning underpin the formation of new capabilities; and communitarian theories of learning overemphasise the social construction of knowledge, while neglecting the agency of the materiality of context

Aeroacoustic source mechanisms of a wavy leading edge undergoing vortical disturbances

High-accuracy numerical simulations are performed to study aeroacoustic source mechanisms of wavy leading edges (WLEs) on a thin aerofoil undergoing vortical disturbances. This canonical study is based on a prescribed spanwise vortex travelling downstream and creating secondary vortices as it passes through the aerofoil’s leading edge. The primary aim of the study is to precisely understand the relationships between the vortex-induced velocity perturbation and the wall pressure fluctuation on the WLE geometry. It is observed that by increasing the size (amplitude) of the WLE the source strength at the peak region is reduced rapidly to a certain point, followed by a saturation stage, while at the root (trough) it remains fairly consistent regardless of the WLE size. This observation is demonstrated to be the consequence of three-dimensional vortex dynamics taking place along the WLE. One of the most profound features is that a system of horseshoe-like secondary vortices are created from the WLE peak region upon the impingement of the prescribed vortex. It is found that the horseshoe vortices produce a significantly non-uniform velocity perturbation in front of the WLE leading to the disparity in the source characteristics between the peak and root. The alterations to the impinging velocity perturbation are carefully analysed and related to the wall pressure fluctuation in this study. In addition, a semi-analytic model based on Biot–Savart’s law is developed to better understand and explain the role of the horseshoe vortex systems and the source mechanisms

The PL calibration for Milky Way Cepheids and its implications for the distance scale

The rationale behind recent calibrations of the Cepheid PL relation using the Wesenheit formulation is reviewed and reanalyzed, and it is shown that recent conclusions regarding a possible change in slope of the PL relation for short-period and long-period Cepheids are tied to a pathological distribution of HST calibrators within the instability strip. A recalibration of the period-luminosity relation is obtained using Galactic Cepheids in open clusters and groups, the resulting relationship, described by log L/L_sun = 2.415(+-0.035) + 1.148(+-0.044)log P, exhibiting only the moderate scatter expected from color spread within the instability strip. The relationship is confirmed by Cepheids with HST parallaxes, although without the need for Lutz-Kelker corrections, and in general by Cepheids with revised Hipparcos parallaxes, albeit with concerns about the cited precisions of the latter. A Wesenheit formulation of Wv = -2.259(+-0.083) - 4.185(+-0.103)log P for Galactic Cepheids is tested successfully using Cepheids in the inner regions of the galaxy NGC 4258, confirming the independent geometrical distance established for the galaxy from OH masers. Differences between the extinction properties of interstellar and extragalactic dust may yet play an important role in the further calibration of the Cepheid PL relation and its application to the extragalactic distance scale.Comment: Accepted for Publication (Astrophysics & Space Science

The Role of Animal Models for Research on Severe Malaria

The Role of Animal Models for Research on Severe Malari

Invasion genetics of the Pacific oyster Crassostrea gigas in the British Isles inferred from microsatellite and mitochondrial markers

The Pacific oyster, Crassostrea gigas, native to northeast Asia, is one of the most important cultured shellfish species. In Europe, Pacific oysters first settled along the Atlantic coasts of France at the end of the 1960s but rapidly spread and are now widely established. Twenty-two sites in the United Kingdom (UK), Ireland, Denmark, France and Spain were sampled to assess genetic diversity and differentiation. Hatchery-propagated stocks from two hatcheries located in the UK also were included. Two main genetic clusters were identified from pairwise genetic differentiation indexes, Bayesian clustering methods or neighbour-joining analysis, based on 7 microsatellite loci: (1) a Northeast cluster (including feral samples from East England, Ireland and Denmark as well as UK hatchery stocks) and (2) a Southwest cluster (including samples from South Wales, South West England, France and Spain). The Southwest cluster had significantly higher allelic richness (A) and expected heterozygosity (He) (A: 45.68, He: 0.928) than in the Northeast (A: 26.58, He: 0.883); the two diverging by a small but significant FST value (FST=0.017, 95% CI: 0.014-0.021). A 739-bp fragment of the major noncoding region of the mitochondrial genome was sequenced in 248 oysters from 12 of the studied samples in Europe and in 25 oysters from Miyagi prefecture (Japan). A total of 81 haplotypes were found. Haplotype frequency analyses identified the same two clusters observed using microsatellites. This study highlights how the number and size of introduction events, aquaculture practices, genetic bottlenecks followed by genetic drift and natural dispersal can act concurrently to shape the genetic diversity and structure of introduced populations

Predicted 10-year risk of cardiovascular disease is influenced by the risk equation adopted: a cross-sectional analysis

Background Validated risk equations are currently recommended to assess individuals to determine those at ‘high risk’ of cardiovascular disease (CVD). However, there is no longer a risk ‘equation of choice’. Aim This study examined the differences between four commonly-used CVD risk equations. Design and setting Cross-sectional analysis of individuals who participated in a workplace-based risk assessment in Carmarthenshire, south Wales. Method Analysis of 790 individuals (474 females, 316 males) with no prior diagnosis of CVD or diabetes. Ten-year CVD risk was predicted by entering the relevant variables into the QRISK2, Framingham Lipids, Framingham BMI, and JBS2 risk equations. Results The Framingham BMI and JBS2 risk equations predicted a higher absolute risk than the QRISK2 and Framingham Lipids equations, and CVD risk increased concomitantly with age irrespective of which risk equation was adopted. Only a small proportion of females (0–2.1%) were predicted to be at high risk of developing CVD using any of the risk algorithms. The proportion of males predicted at high risk ranged from 5.4% (QRISK2) to 20.3% (JBS2). After age stratification, few differences between isolated risk factors were observed in males, although a greater proportion of males aged ≥50 years were predicted to be at ‘high risk’ independent of risk equation used. Conclusions Different risk equations can influence the predicted 10-year CVD risk of individuals. More males were predicted at ‘high risk’ using the JBS2 or Framingham BMI equations. Consideration should also be given to the number of isolated risk factors, especially in younger adults when evaluating CVD risk

NK1-r antagonist treatment comparable to decompressive craniectomy in reducing intracranial pressure following stroke

Background and Purpose: The morbidity and early mortality associated with stroke is largely attributable to cerebral edema and elevated intracranial pressure (ICP). Existing pharmacotherapies do not target the underlying pathophysiology and are often ineffective in sustainably lowering ICP, whilst decompressive craniectomy (DC) surgery is life-saving yet with surgical/peri-operative risk and increased morbidity in the elderly. Accordingly, there is an urgent need for therapies that directly target the mechanisms of edema genesis. Neurogenic inflammation, mediated by substance P (SP) binding to the tachykinin NK1 receptor (NK1-r), is associated with blood-brain barrier (BBB) disruption, cerebral edema and poor outcome post-stroke. NK1-r antagonist treatment ameliorates BBB dysfunction and cerebral edema in rodent stroke models. However, treatment has not been investigated in a large animal model, an important step toward clinical translation. Consequently, the current study compared the efficacy of NK1-r antagonist treatment to DC surgery in reducing ICP post-stroke in a clinically relevant ovine model. Methods: Anesthetized female Merino sheep (65 ± 6 kg, 18-24 months) underwent sham surgery (n = 4) or permanent middle cerebral artery occlusion (n = 22). Stroke animals were randomized into one of 5 treatments: 1×NK1 bolus (4 h), 2×NK1 bolus (4 h;9 h), 3×NK1 bolus (4 h;9 h;14 h), DC surgery (performed at 4 h) or saline vehicle. ICP, blood pressure and blood gasses were monitored for 24 h post-stroke. At 24 h post-stroke anesthetized animals underwent MRI followed by perfusion and brains removed and processed for histological assessment. Results: 2×NK1, 3×NK1 administration or DC surgery significantly (p < 0.05) reduced ICP compared to vehicle. 1×NK1 was ineffective in sustainably lowering ICP. On MRI, midline shift and cerebral edema were more marked in vehicles compared to NK1-r treatment groups. Conclusion: Two or three boluses of NK1-r antagonist treatment reduced ICP comparable to DC surgery, suggesting it may provide a novel alternative to invasive surgery for the management of elevated ICP.Annabel J. Sorby-Adams, Anna V. Leonard, Jan W. Hoving, Nawaf Yassi, Robert Vink, Adam J. Wells and Renée J. Turne