92 research outputs found

    Efficiency improvement in induction motor by slitted tooth core design

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    U ovom istraživanju predložen je novi dizajn kako bi se poboljšala učinkovitost rada asinkronih motora. U predloženom dizajnu primjenjeni su procijepi u sredini zubi statora i rotora. U ovim procijepljenim modelima dubina i širina procijepa su optimizirani uz pomoć programa Magnetska metoda konačnih elemenata (FEMM) i koristeći Metodu konačnih elemenata (FEM). Za prikaz poboljšanja izvedbe, predloženi model motora i referentni model motora su uspoređeni u definiranim pogonskim tačkama za vrijednosti kao što su ulazna i izlazna snaga, ulazna struja, faktor snage, efikasnost i gubitci. Zbog smanjenja gubitaka željeza i bakra, ukupni gubitak u motoru je smanjen, a povećana je efikasnost za definiranu pogonsku tačku za 1,869%. U modeliranju korišten je 3 kW kavezni asinkroni motor.In this study, a new design was suggested in order to improve the performance of induction motors. In the proposed design, slits were applied in the middle of stator and rotor teeth. In these slitted models, the depth and width of slits were optimized with Finite Element Method Magnetics (FEMM) software using Finite Elements Method (FEM). To show performance improvement, suggested motor model and a reference motor model were compared at the rated operating point for the values such as input and output power, input current, power factor, efficiency and losses. Because of the decreases in both iron and copper losses, total losses in motor were reduced and the efficiency for rated operating point was improved by 1,869%. In the modelling, 3 kW squirrel-cage induction motor was used

    Hypermethylation of tumor suppressor genes in gastric cancer: associations with demographic and clinicopathological characteristics

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    Background: Gastric cancer (GC) is one of the most common cancers worldwide. Despite the declining prevalence in Western countries, it is still a major health problem in Turkey and Asian countries. In the current study, we investigated the hypermethylation status of 25 TSGs in GC. Furthermore, the association between hypermethylation status of these TSGs and some demographic and clinicopathological characteristics were investigated.Methods: Formalin-fixed paraffin-embedded tissue samples obtained from 27 patients with GC and genomic DNA isolated from these tissues. To compare the methylation status of 25 TSGs, methylation-specific multiplex ligation-dependent probe amplification (MS–MLPA) technique was used. Results were evaluated in terms of age, gender, positive lymph node status, lymphovascular invasion, perineural invasion, mortality and five-years of survival, retrospectively.Results: Tumor suppressor gene hypermethylation was detected 16 (59.3%) of 27 GC tissues. Patients with hypermethylation-detected and patients with no hypermethylation-detected in their TSGs were classified as group 1 and group 2, respectively. The mean age of group 1 was 66.38±7.43 and the mean age of group 2 was found as 58.18±11.12 (p= 0.03). Hypermethylation was detected in 12 of 25 TSGs in patients with GC. Hypermethylation was detected as 51.8% for WT1, 40.7% for ESR1, 18.5% for CDH13, 14.8% for MSH6 and CD44, 7.4% for TP73 and PAX5 genes in the tumor tissues of patients with GC. Mean positive lymph node number was 8.81±5.38 in group 1 and 4.81±3.21 in group 2 (p= 0.037). Lymphovascular invasion, perineural invasion, mortality and five-years of mean survival were not statistically different between group 1 and group 2 (p>0.05 for all comparisons).Conclusions: Hypermethylation frequency of certain tumor suppressor genes may increase with advancing age and with positive lymph nodes in gastric cancer patients.

    The preoperative serum CA125 can predict the lymph node metastasis in endometrioid-type endometrial cancer

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    Objectives: To evaluate the predictive value of preoperative CA125 in extra-uterine disease and its association with poorprognostic factors in endometrioid-type endometrial cancer (EC).Material and methods: A total of 423 patients with pathologically proven endometrioid-type EC were included in thestudy. The association between preoperative CA125 level and surgical–pathological factors was evaluated. The conventional cut-off value was defined as 35 IU/mL.Results: A high CA125 level ( > 35 IU/mL) was significantly associated with all of the studied poor prognostic factors,except grade. The risk of lymph node metastasis (LNM) increased from 15.9% to 45.7% when CA125 level was > 35 IU/mL (p < 0.05). The optimal cut-off value for the prediction of LNM in patients aged > 50 years was determined to be 16 IU/mL (sensitivity, specificity, positive predictive value, and negative predictive value were 71%, 60%, 35%, and 87%, respectively.)Conclusions: Preoperative CA125 level was significantly related with the extent of the disease and LNM. The age-dependent cut-off level of CA125 can improve the prediction of LNM in endometrioid-type EC. For older patients, CA125 level of > 16 IU/ml could be used to predict LNM. However, further studies are needed to evaluate the appropriate cut-off level of CA125 for younger patients

    “Hinge” Mitral Valve Repair for Active Valve Endocarditis and Long-term Follow-up Transesophageal Echocardiography Study.

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    Ciljevi: Liječenje mitralnog zalistka u endokarditisu zalistka izazovna je tema, a rekonstrukcija je poželjnija u odnosu na zamjenu, no često zahtijeva opsežan debridman vegetacije, infi ciranoga tkiva i složenu rekonstrukciju tijekom aktivne faze. Metode: Donosimo prikaz uspješne rekonstrukcije mitralnoga zalistka u pacijenta s aktivnim endokarditisom. Rezultati: Postoperativna ehokardiografi ja nije pokazala regurgitaciju na novoformiranom mitralnom zalistku. Zaključak: Reparacija mitralnoga zalistka perikardijanom zakrpom prvi je izbor liječenja aktivnog endokarditisa, koja je tehnički zahtjevna, no ima zadovoljajuće rezultate. Rekonstrukcija mitralnog zalistka ovom metodom ne samo da podržava otvaranje područja mitralnih komisura, već i potpomaže ponovno uspostavljanje fizilološkoga kretanja mitralnoga zalistka.Aims: Mitral valve treatment in valve endocarditis is currently a challenging issue. Repair is preferred to replacement but it often requires extensive debridement of vegetation and infected tissue as well as complex reconstruction in the active phase. Methods: We report on a successful repair of the mitral valve, as described in the case of active endocarditis. Results: Postoperative echocardiography demonstrated no regurgitation at the newly formed mitral valve. Conclusion: First preference is pericardial repair, a technically difficult procedure but with satisfactory results in mitral repair for active endocarditis. Reconstruction of the mitral commissure with this technique not only supports the opening of the commissural area but also helps regain the physiological motion of the mitral valve

    Safety and efficacy of PNL vs RIRS in the management of stones located in horseshoe kidneys: A critical comparative evaluation

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    Aim: To assess the efficacy and safety of two different techniques (Percutaneous nephrolithotomy (PNL) vs Retrograde intrarenal surgery (RIRS)) in the management of stones in patients with horseshoe kidneys (HSK). Patients and methods: Departmental files of 88 cases with radiopaque kidney stones in horseshoe kidneys undergoing two different approaches (PNL vs RIRS) were evaluated with respect to the success and complication rates of in a retrospective manner. In addition to the factors related with the procedures (success and complication rates, additional procedures), patient and stone characteristics were all well evaluated. Findings obtained in both groups were evaluated in a comparative manner with respect to the statistical significance. Results: Stone free rates were comparable in both groups after 1-week period (81.6% PNL vs 80% RIRS). As well as 3 months evaluation (84.2% PNL and 82.0% RIRS). The percentage of the cases with residual fragments (> 4 mm) were similar in both groups and while all PNL procedures were completed in one session, mean number of RIRS sessions was higher (1.22 ± 0.05). Mean duration of the procedure was slightly higher in RIRS group and based on Clavien scoring system, despite a higher risk of Hb drop noted in patients treated with PNL, all complication rates were found to be similar in both groups. Conclusion: Our results demonstrate that of the available minimally invasive treatment alternatives, both PNL and RIRS could be safe and effective alternatives for renal stone removal in patients with HSK

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Evaluation of volatile compounds in chicken breast meat using simultaneous distillation and extraction with odour activity value

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    WOS: 000337664600005Limited information is available about the volatile components of raw chicken meat; therefore the current study was aimed at chicken meat volatiles. In addition, odour activity values (OAV) were used to evaluate potent volatile components of the chicken meat. Simultaneous distillation and extraction with dichloromethane was used to obtain volatile components. The volatile compounds were analysed by gas chromatography-mass spectrometry. A total of 33 compounds were identified and quantified in the sample. Volatile acids, esters and alcohols were the dominant volatiles in the chicken breast meat. On the basis of OAV, the most important aroma compounds identified in the extract were hexanal and (E)-2-heptenal, which were described as the green-fresh odour and green-cheesy-fatty odour, respectively

    Low Genetic Diversity in Turkish Populations of Wels Catfish Silurus glanis L., 1758 (Siluridae, Pisces) Revealed by Mitochondrial Control Region Sequences

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    turan, davut/0000-0002-9586-6223; Kalayci, Gokhan/0000-0003-1255-496X; AKSU, ISMAIL/0000-0002-2104-9888WOS: 000575615800006This study aimed to investigate the genetic diversity and population structure of Wels catfish Silurus glanis L. 1758 in Turkey using squences of the mitochondrial DNA control region the 887-bp fragment of D-loop was aligned for 112 S. glanis individuals from ten wild populations in Turkey, defined by 29 polymorphic sites comprising 16 haplotypes. the low haplotype diversity and nucleotide diversity within each population ranged from 0.000 to 0.378 and from 0.0000 to 0.0045, respectively. Analysis of molecular variance showed significant genetic differentiation among ten populations (F-ST =0.940; P0.05), Harpending's raggedness index (Hri; 0,300, P>0.05) and Ramos-Onsins & Rozas (R2; 0,0771, P>0.05), supporting population neutrality.Recep Tayyip Erdogan University Research FundRecep Tayyip Erdogan University [2009.103.01.2]This study was funded by Recep Tayyip Erdogan University Research Fund (Project No: 2009.103.01.2)

    USING TOPSIS METHOD WITH LAPLACE CRITERION TO SELECT OPTIMUM AIRLINE

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    In this study, for evaluating subjective features that provides preference of airline companies to others the method TOPSIS has been used. Whilst calculating the weights of the criteria Laplace Criterion had been used. The importance of the study is that this is a unique application in air cargo industry
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