Neural network based MOS transistor geometry decision for TSMC 0.18 mu process technology

6th International Conference on Computational Science (ICCS 2006) -- MAY 28-31, 2006 -- Reading, ENGLANDWOS: 000238417500084In sub-micron technologies MOSFETs are modeled by complex nonlinear equations. These equations include many process parameters, terminal voltages of the transistor and also the transistor geometries; channel width (W) and length (L) parameters. The designers have to choose the most suitable transistor geometries considering the critical parameters, which determine the DC and AC characteristics of the circuit. Due to the difficulty of solving these complex nonlinear equations, the choice of appropriate geometry parameters depends on designer's knowledge and experience. This work aims to develop a neural network based MOSFET model to find the most suitable channel parameters for TSMC 0.18 mu technology, chosen by the circuit designer. The proposed model is able to find the channel parameters using the input information, which are terminal voltages and the drain current. The training data are obtained by various simulations in the HSPICE design environment with TSMC 0.18 mu m process nominal parameters. The neural network structure is developed and trained in the MATLAB 6.0 program. To observe the utility of proposed MOSFET neural network model it is tested through two basic integrated circuit blocks.Intel Corp, IBM, SGI, Microsoft Res, EPSRC, Springer, ACET Ctr, Univ Reading, SIAM, IMACS, UK e Sci Programm

The Effect of Domestic Violence During Pregnancy on Cortisol Hormone Release, Breastfeeding, and Newborn

This study was conducted to determine the effect of domestic violence during pregnancy on the cortisol hormone release, preterm birth, low birth weight, and breastfeeding status. The cross-sectional study was conducted with 255 pregnant women in a Family Health Centre in the Southeastern Anatolia Region of Turkey between October 2017 and August 2018. The questionnaire, DVWDS (Domestic Violence to Women Determination Scale) and Breastfeeding Self-Efficacy Scale were used to collect the data. In the present study, the pregnant women were followed up three times. The first follow-up was applied to the pregnant women in the second trimester, the second follow-up was applied to those in the third trimester, and the third follow-up was applied to the postpartum women. At each follow-up from newborn, cortisol hormone level was taken with saliva and evaluated. It was determined that 9.8% of the pregnant women participating in the study were exposed to violence by their partners. An important result was found that those who were exposed to domestic violence during their pregnancy gave birth in the 37th week (p < 0.05). It was seen that the babies of those exposed to domestic violence during pregnancy had a higher mean cortisol hormone level (p < 0.05). It was found that the mean score of the Breastfeeding Self-Efficacy Scale in the third follow-up was lower for those who were exposed to domestic violence during pregnancy than those who were not (p < 0.05). It was observed during the pregnancy that domestic violence affected cortisol hormone secretion, breastfeeding after birth and newborn health

Investigation of some metals in honey samples from West Mediterranean region of Turkey

WOS: 000510738500001PubMed: 31737225Analysis of elements content in honey is important for honey quality and safety and for monitoring of environmental pollution. The levels of 22 elements, aluminum (Al), barium (Ba), calcium (Ca), cadmium (Cd), chromium (Cr), cobalt (Co), iron (Fe), copper (Cu), potassium (K), magnesium (Mg), manganese (Mn), nickel (Ni), sodium (Na), lead (Pb), strontium (Sr), silver (Ag), bismuth (Bi), gallium (Ga), indium (In), lithium (Li), thallium (Tl) and zinc (Zn), were determined in 70 samples obtained from beekeepers located in the West Mediterranean region of Turkey. Determination of elements content was carried out using ICP-OES. Chromium, Co, Cd, Ag, Bi, In and Tl were not detected in any of the tested honey samples. The most abundant metal was K which has an overall average of 764.26 mg kg(-1). Higher concentrations of Pb, Ni, Mg, Na, K and Mn were found in the samples obtained from Burdur compared to other provinces. The levels of Cu were statistically lower in Antalya in comparison to other regions. No significant differences were observed in Al, Zn, Fe, Sr, Ba, Ca and Ga levels between regions. The differences in the chemistry of honey samples collected from different regions may be due to geochemical soil composition and geographical differences. Their levels were below to the European limits and the honeys are safe for human consumption. (C) 2019 Urmia University. All rights reserved

A Current Source Converter-Based Active Power Filter for Mitigation of Harmonics at the Interface of Distribution and Transmission Systems

A medium-power current source converter (CSC)-based shunt active power filter (APF) system is designed and implemented to suppress the amplification of low-order harmonics at the medium-voltage (MV) interface bus between the distribution and transmission systems, owing to the presence of large shunt capacitor banks installed only for reactive power compensation. Four CSC-based APF modules designed at 1.0 kV are operated in parallel and connected to the 31.5-kV MV bus via a specially designed coupling transformer. In each APF module, a specially designed LC-type input filter eliminates the switching ripples, and active damping method embedded into the control software suppresses harmonic frequencies around the corner frequency of the input filter. The resulting system can operate at relatively high frequencies in the range from 2.0 to 3.0 kHz, depending upon which selected harmonics among 5th, 7th, 11th, and 13th are to be eliminated. Furthermore, in order to reduce the installed capacity of CSCs, selective harmonic amplification method is applied to the APF system described in the paper. MV APF system has been built as a mobile system for temporary connection to a problematic MV interface bus until a permanent solution is found for that location in the distribution system

A View from Young Oncologists on Clinical Trials in Turkey: Obstacles and Solution Proposals

There is a new improvement in oncology nearly in every day as a result of preclinical or clinical. As the number of publication per capita, Turkey is far behind the other developed European countries. For example, the number of publications in oncology field is 2.134.964 in the world, it is 15.576 in our country. The most important obstacles for clinical trials in Turkey may be listed as financial problems, difficulties of working conditions, time limitation due to work intensity, inadequate experienced/trained man-power, absence of assistance team at all steps of a scientific trial, difficulties faced during project planning and ethics committee submissions, and lack of motivation. In this article, we, as young oncologists, aimed to discuss the place of Turkey in areas of scientific and clinical trials in the world; underlying causes for inadequate number, type and quality of national studies and possible solution proposals in our country

The recurrence with isolated intra-abdominal lymph node in patients with colorectal cancer: A study of the Turkish Descriptive Oncological Researches Group (intra-abdominal lymph node and colon cancer)

Background: This study aimed to identify the risk factors related in recurrence with isolated intra-abdominal lymph node metastasis in patients with colorectal cancer. Methods: This is a retrospective, cross-sectional study of 21 colorectal cancer patients with isolated intra-abdominal lymph node metastases. Preoperative demographic and laboratory/postoperative histological features of these patients were been analyzed. Results: Lymphovascular and perineural invasion and mutant-type K-ras status were more common in the study patients. In addition, a significant correlation was been detected between lymphovascular and perineural invasion, preoperative serum CEA level, preoperative thrombocyte count, mutant-type K-ras status, and pathological N3 disease. Mutant-type K-ras status and the presence of lymphovascular invasion were independent prognostic risk factors for isolated intra-abdominal lymph node metastasis. Conclusions: The presence of lymphovascular invasion and mutant-type K-ras status may be poor prognostic risk factors for isolated intra-abdominal lymph node metastasis in patients with colorectal cancer. However, studies involving larger patient series, molecular indicators, and cohorts with metastasis in other areas are been needed to verify this study

Sunitinib for Patients with Metastatic Non-clear Cell Renal Cell Carcinoma: A Multicenter Retrospective Turkish Oncology Group Trial

Aim: This study aimed to assess the clinical efficacy and toxicity of sunitinib, a targeted-agent, for non-clear cell renal cell carcinoma. Patients and Methods: Sixty-three patients with complete clinical data from 13 oncology Centers were retrospectively evaluated. Outcomes analyzed were objective response rate (ORR), progression-free survival (PFS), overall survival (OS) and adverse events. Results: The median age of all patients, 38 men (60.3%) and 25 women (39.7%), was 63 years (range=25-82 years). Histological subtypes included 46 (88%) cases of papillary RCC, 10 of chromophobe, and 7 unclassified cases. Median treatment duration was seven months (range=2-86 months). At the time of this analysis, 52 patients had discontinued treatment, 33 of whom had died. Treatment discontinuation was due to disease progression in 43 patients, and toxicity in nine. Dose interruption was necessary in 22 (34.9%) patients, and dose reduction in 27 (42.9%). The objective response rate and disease control rate were 11.1% and 63.5%, respectively. The median PFS and OS were 7.6 months (95% confidence interval (CI)=5.5-9.7 months) and 22.0 months (95% CI=13.4-30.6 months), respectively, with 1-year rates of 64.7% and 33.7%, respectively. Conclusion: Clinical outcome of the metastatic non-clear cell RCC patients with sunitinib treatment seemed to be worse than the historical data of clear cell RCC patients, in terms of PFS, OS and objective response. New and more effective targeted-therapies and better understanding of the underlying molecular processes are necessary to improve survival outcome for these patients