Human Resources and Employment

Import 01/09/2009V předložené práci je zpracována otázka zaměstnanosti a lidských zdrojů. Ve své práci jsem se pokusila popsat nové pojmy , které nás obklopují naším vstupem do Evropské unie. Novým společenstvím jehož jsme součástí se nás týká jak rozšířený trh práce, geografická mobilita, tak i další vzdělávání - naše seberealizace . Zároveň je poukázáno na reformy, sociální ochranu a trh práce v členských státech EU. Následně je začleněno porovnání vybraných aspektů a popsáno postavení České republiky v této otázce. Zmíněn je jak vývoj naší země v oblasti zaměstnanosti v minulých letech, tak i mobilita v rámci Evropské unie. V třetí části je popsán vývoj zaměstnanosti na základě zpracování zveřejněných dat s výhledem strategie dalšího vývoje. Cílem této práce je seznámení s novou problematikou v návaznosti na ekonomiku a vývoj nového společenství. Závěr práce je věnován aktuálnímu stavu ekonomiky s výhledem do budoucnosti.In presented document the employment and human resources issues are discussed as impacted by Czech Republic joinig the Europia Union. New facts are shown having connection to an extension of labor market, changes on geographical mobility as well as in the area of lifelong education. In the same context it tis referred to reforms, social protection and labor market in member states of the Europia Union. Pricipal part of the work is dedicated to comparison of selected aspects and status of Czech Republic within Europia Union. Final part is devoted to recent status of economy in the area of employment and with outlook on future.Prezenční545 - Institut ekonomiky a systémů řízenívýborn

Forebrain Ischemic Stroke and the Phenomenon of Ischemic Tolerance: Is Homocysteine Foe or Friend?

Hyperhomocysteinemia (hHCy) is a recognized comorbid risk factor of human brain stroke. We overview here the recent data on the homocysteine (Hcy) metabolism and on the genetic and metabolic causes of hHCy‐related neuropathologies. In context of our results which detected an increased oxidative stress in hyperhomocysteinemic rats, we discuss here the role of free radicals in this disorder. Brain ischemia‐reperfusion causes delayed neuronal death. Ischemic tolerance evoked by preconditioning (IPC) represents a phenomenon of central nervous system (CNS) adaptation to any subsequent ischemia. The paper describes changes in the mitogen‐activated protein kinases (MAPKs) protein pathways, and apoptotic markers were used to follow the degeneration process. Our studies provide evidence for the interplay and tight integration between extracellular signal‐regulated kinase (ERK) and p38 MAPKs signaling mechanisms in response to the hHCy and also in association with brain ischemia/IPC challenge. Recognition of the effects of risk factors in the ischemic tolerance would lead to improved therapeutics, especially the brain tissue

Synaptic Loss, ER Stress and Neuro-inflammation Emerge Late in the Lateral Temporal Cortex and Associate with Progressive Tau Pathology in Alzheimer’s Disease

Acknowledgements We would like to deeply thank all donors and their families for the tissue provided for this study. Human tissue samples were supplied by the Brains for Dementia Research programme, jointly funded by Alzheimer’s Research UK, the Alzheimer’s Society and the Medical Research Council, and sourced from the MRC London Neurodegenerative Diseases Brain Bank, the Manchester Brain Bank, the South West Dementia Brain Bank (SWDBB), the Newcastle Brain Tissue Resource and the Oxford Brain Bank. The Newcastle Brain Tissue Resource and Oxford Brain Bank are also supported by the National Institute for Health Research (NIHR) Units. The South West Dementia Brain Bank (SWDBB) receives additional support from BRACE (Bristol Research into Alzheimer’s and Care of the Elderly). Use of human tissue for this work was approved by Brains for Dementia Research from London – City and East NRES committee 08/H0704/128+5. The work presented here was funded by Alzheimer’s Research UK (Grant refs: ARUK-PPG2014A-21, ARUK-NSG2015-1, ARUK-NCG2017A-3 awarded to DK and BP). HB was supported by an Alzheimer’s Society Doctoral Training Centre grant (grant ref: 228) to BP. MK’s participation in the project was funded by ARUK Scotland Network pump priming award to DK and BP. Antibodies CP13 and PHF1 were generously provided by Prof. Peter Davies. TOC1 antibodies were a gift from Nicholas Kanaan at Michigan State University (originally created by Lester Binder at Northwestern University). Funding The work presented here was funded by Alzheimer’s Research UK (Grant refs: ARUK-PPG2014A-21, ARUK-NSG2015-1, ARUK-NCG2017A-3 awarded to DK and BP). HB was supported by an Alzheimer’s Society Doctoral Training Centre grant (grant ref:228) to BP. MK’s participation in the project was funded by ARUK Scotland Network pump priming award to DK and BP.Peer reviewedPublisher PD

Metabolic indicators in cattle breeding

Potential associations among glucose tolerance test (GTT) as ability to metabolize glucose, estimated breeding values (EBVs) for milk traits and selected candidate gene polymorphisms were evaluated.  German Holstein sires, born in 1993 and between years 1999 and 2003, were analysed. A few significant negative correlations between milk and protein yield and GTT were found in sires born in 1993. Only a few significant correlations were found for protein yield, protein percentage and for fat percentage and yield (sires born in different years). Any linkage of DGAT1, GH1, GHR, FASN and OLR1 to GTT was found.Keywords: milk, glucose, correlation, breeding valuesReferencesDeepa, P.M. et al. (2015) Alteration in clinico-biochemical profile and oxidative stress indices associated with hyperglycaemia with special reference to diabetes in cattle-a pilot study. Trop. Anim. Health Prod., Vol. 47, no. 1, pp. 103-109. DOI:10.1007/s11250-014-0691-5Di Stasio, L. et al. (2005) Polymorphism of the GHR gene in cattle and relationships with meat production and quality. Anim. Genet., Vol. 36, pp. 138–140.Grisart, B. et al. (2002) Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition. Genome Res., Vol. 12, pp. 222-231.Kneeskern, S. G. et al. (2016) Effects of chromium supplementation to feedlot steers on growth performance, insulin sensitivity, and carcass characteristics. J. Anim. Sci., Vol. 94, no. 1, pp. 217-226. DOI: 10.2527/jas2015-9517 Khatib, H. et al. (2006) Association of the OLR1 Gene with Milk Composition in Holstein Dairy Cattle. J. Dairy Sci., Vol. 89, pp. 1753–1760.Morris, C. A. (2007) Fatty acid synthase effects on bovine adipose fat and milk fat. Mamm. Genome, Vol. 18, pp. 64–74.Panicke, L. et al. (2000) Relationships between parameters of the glucose tolerance test by young sires and estimated their breeding values. Arch. Tierz., Vol. 43, pp. 231-239

Modification of Titania-Based Nanoparticles for Anode Materials of Li Ion Battery

The present poster contribution aims at optimization of electrochemical properties of titania (N doped anatase TiO2 / N) and Li-Ti ternary oxides (Li4Ti5O12, LTO) with respect to their performance as anode materials in Li-ion battery by using mechanochemical effects

Association study of bovine candidate loci to meat quality

The aim of this study was to determine the potential association between candidate loci and  indicators of meat quality in Czech Simmentals. For the study, loci for calpain (CAPN530) and myostatin (MSTN) were chosen. The  analysis revealed 258 bulls (locus CAPN530) and 228 bulls (locus MSTN) of Czech Simmental cattle. Genotyping was carried out by PCR/RFLP method. The association analysis was performed for polymorphisms of both loci and shear force of the raw and grilled meat on the 1st, 14th and 28th day after slaughter. The CAPN530 locus showed a statistically significant effect on the power cut for raw and grilled meat in the 1st day after the slaughter (P<0.05), and for grilled meat significant changes were stated in the 14th and 28th day post mortem (P<0.05). No significant relationships in locus MSTN between genotype and shear force (P<0.05) were found. The MSTN genotype affected the ability to bind water. However, the findings should be interpreted with caution to the unequal representation of genotypes for the locus MSTN in the study

Nuclear Power Plant Staff VR Training

Cílem bakalářské práce je vytvořit aplikaci pro virtuální realitu určenou pro jaderné inženýrství, která by usnadňovala trénink personálu jaderné elektrárny se zaměřením na pracovníky, kteří pracují na pracovištích s rizikem ionizujícího záření. Práce studuje jak problematiku vývoje aplikací pro virtuální realitu, tak radiační ochranu a bezpečnost. Primárním zaměřením bakalářské práce je nabídnout způsob optimalizace prací a naplánovaní činností tak, aby nebyly překročeny limity ozáření pracovníků. Výsledná aplikace je určena pro Oculus Rift S.ObhájenoThe aim of this thesis is to create a VR application intended for use in nuclear engineering. It should make training of nuclear power plant personnel easier and more effective and focus on workers exposed to ionizing radiation. This work delves into research on VR application development as well as protection against radiation. The final application is designed for Oculus Rift S

Fashion blog as a marketing tool

Bachelor thesis is focused on exploring promotion of brands and companies on specific Czech fashion blogs. At the same time investigates the reaction of readers and awareness on the promotion of blogs and its actual impact on these readers. The theoretical part contains information about marketing, communication process, forms of communication, communication and communication mix on the internet. Further information in this section is about social networks and their use in business, the characteristics of a blog, the blog history, whether abroad or in the Czech Republic. The practical part presents the analysis of co-operation brands with specific Czech fashion bloggers and results of a questionnaire survey among the readers