287 research outputs found

    Procesos de gentrificación, despojo urbano y elitización del espacio en el zona centro de Guadalajara

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    En el siguiente documento se rescató la experiencia, el aprendizaje y los hallazgos del Proyecto de Aplicación Profesional: Observatorio en ruta, el cual se basó en una investigación urbana en el centro histórico de Guadalajara con el fin de observar el proceso de gentrificación que gracias a los proyectos urbanísticos de la zona ocurre. Con una metodología de investigación cualitativa se realizó trabajo de campo, análisis documental, seminarios especializados en temáticas urbanas/sociales, entrevistas y documentación audiovisual. El grupo conformado por arquitectos y psicólogas logró tener mayor alcance del Centro histórico de Guadalajara dividiéndolo en cuatro cuadrantes (Refugio, Mezquitan, Mexicaltzingo y Mercado Corona-Centro) en los que en cada uno existe un proyecto grande que busca rehabilitar y modificar el centro.ITESO, A.C

    Numerical evidence for `multi-scalar stars'

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    We present a class of general relativistic soliton-like solutions composed of multiple minimally coupled, massive, real scalar fields which interact only through the gravitational field. We describe a two-parameter family of solutions we call ``phase-shifted boson stars'' (parameterized by central density rho_0 and phase delta), which are obtained by solving the ordinary differential equations associated with boson stars and then altering the phase between the real and imaginary parts of the field. These solutions are similar to boson stars as well as the oscillating soliton stars found by Seidel and Suen [E. Seidel and W.M. Suen, Phys. Rev. Lett. 66, 1659 (1991)]; in particular, long-time numerical evolutions suggest that phase-shifted boson stars are stable. Our results indicate that scalar soliton-like solutions are perhaps more generic than has been previously thought.Comment: Revtex. 4 pages with 4 figures. Submitted to Phys. Rev.

    Casimir-like tunneling-induced electronic forces

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    We study the quantum forces that act between two nearby conductors due to electronic tunneling. We derive an expression for these forces by calculating the flux of momentum arising from the overlap of evanescent electronic fields. Our result is written in terms of the electronic reflection amplitudes of the conductors and it has the same structure as Lifshitz's formula for the electromagnetically mediated Casimir forces. We evaluate the tunneling force between two semiinfinite conductors and between two thin films separated by an insulating gap. We discuss some applications of our results.Comment: 8 pages, 3 figs, submitted to Proc. of QFEXT'05, to be published in J. Phys.

    Comparative Effects of Triflusal, S-Adenosylmethionine, and Dextromethorphan over Intestinal Ischemia/Reperfusion Injury

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    Ischemia/reperfusion (I/R) is a condition that stimulates an intense inflammatory response. No ideal treatment exists. Triflusal is an antiplatelet salicylate derivative with anti-inflammatory effects. S-adenosylmethionine is a metabolic precursor for glutathione, an endogenous antioxidant. Dextromethorphan is a low-affinity N-methyl-D-aspartate receptor inhibitor. There is evidence that these agents modulate some of the pathways involved in I/R physiopathology. Intestinal I/R was induced in rats by clamping the superior mesenteric artery for 60 minutes, followed by 60 minutes of reperfusion. Rats either received saline or the drugs studied. At the end of the procedure, serum concentrations of tumor necrosis factor-alpha (TNF-alpha), malonaldehyde (MDA), and total antioxidant capacity (TAC) were determined and intestinal morphology analyzed. I/R resulted in tissue damage, serum TNF-alpha and MDA elevations, and depletion of TAC. All drugs showed tissue protection. Only triflusal reduced TNF-alpha levels. All drugs lowered MDA levels, but only triflusal and S-adenosylmethionine maintained the serum TAC

    UNA DINÁMICA EXPERIMENTAL EDUCATIVA E INTERACTIVA EN EL MUSEO DE HISTORIA NATURAL “VERA ALLEMAN HAEGHEBAERT ”: LÍNEA DE TIEMPO

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    El Día Internacional de los Museos se celebra cada año el 18 de mayo, fecha para la cual el Museo de Historia Natural “Vera Alleman Haeghebaert”, de la Universidad Ricardo Palma organiza diversas actividades, desde conferencias para el alumnado hasta dinámicas de rigor social que involucren la difusión del conocimiento a diferentes niveles educativos. Es así que se crea la dinámica denominada “Línea de Tiempo”, con una visión educativa apoyada en el conocimiento científico y transformada en una actividad con opción a variaciones según el grado académico de las personas participantes, y que otorga accesibilidad a información sobre la historia de nuestro planeta. Recibiendo cada participante un número de imágenes de especies deflora y fauna extinta, este deberá clasificarlo en el periodo geológico correcto luego de haber recibido la explicación correspondiente en la visita al museo, reforzando así lo expuesto, creando identidad con los fósiles peruanos incluidos en la dinámica y dando a conocer la importancia de la protección de los yacimientos paleontológicos que nos permiten tener este conocimiento

    A nature-inspired design yields a new class of steroids against trypanosomatids

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    This article belongs to the Special Issue Drug Discovery for Neglected DiseasesChagas disease and Leishmaniasis are neglected endemic protozoan diseases recognized as public health problems by the World Health Organization. These diseases affect millions of people around the world however, efficient and low-cost treatments are not available. Different steroid molecules with antimicrobial and antiparasitic activity were isolated from diverse organisms (ticks, plants, fungi). These molecules have complex structures that make de novo synthesis extremely difficult. In this work, we designed new and simpler compounds with antiparasitic potential inspired in natural steroids and synthesized a series of nineteen steroidal arylideneketones and thiazolidenehydrazines. We explored their biological activity against Leishmania infantum, Leishmania amazonensis, and Trypanosoma cruzi in vitro and in vivo. We also assayed their genotoxicity and acute toxicity in vitro and in mice. The best compound, a steroidal thiosemicarbazone compound 8 (ID_1260) was active in vitro (IC50 200 nM) and in vivo (60% infection reduction at 50 mg/kg) in Leishmania and T. cruzi. It also has low toxicity in vitro and in vivo (LD50 >2000 mg/kg) and no genotoxic effects, being a promising compound for anti-trypanosomatid drug development

    Supermassive black holes in scalar field galaxy halos

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    Ultra-light scalar fields provide an interesting alternative to WIMPS as halo dark matter. In this paper we consider the effect of embedding a supermassive black hole within such a halo, and estimate the absorption probability and the accretion rate of dark matter onto the black hole. We show that the accretion rate would be small over the lifetime of a typical halo, and hence that supermassive central black holes can coexist with scalar field halos.Comment: 5 pages RevTex4, no figures. Updated file to match published versio

    VAMOS: a Pathfinder for the HAWC Gamma-Ray Observatory

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    VAMOS was a prototype detector built in 2011 at an altitude of 4100m a.s.l. in the state of Puebla, Mexico. The aim of VAMOS was to finalize the design, construction techniques and data acquisition system of the HAWC observatory. HAWC is an air-shower array currently under construction at the same site of VAMOS with the purpose to study the TeV sky. The VAMOS setup included six water Cherenkov detectors and two different data acquisition systems. It was in operation between October 2011 and May 2012 with an average live time of 30%. Besides the scientific verification purposes, the eight months of data were used to obtain the results presented in this paper: the detector response to the Forbush decrease of March 2012, and the analysis of possible emission, at energies above 30 GeV, for long gamma-ray bursts GRB111016B and GRB120328B.Comment: Accepted for pubblication in Astroparticle Physics Journal (20 pages, 10 figures). Corresponding authors: A.Marinelli and D.Zaboro

    Collective mapping: participatory approaches to community health-disease-care process

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    La atención primaria de la salud renovada entiende a la salud como un derecho que busca la construcción de la ciudadanía a través de la participación comunitaria (De Lellis, 2015). Esto genera un desafío en lo que respecta a los modos de trabajar en conjunto con las poblaciones ya que exige nuevas modalidades de trabajo conjunto tanto en la identificación de necesidades como en la gestión del sistema de salud. El reconocimiento del lugar en donde se desarrolla la vida cotidiana es indispensable para identificar los espacios y los modos de vida que se desenvuelven en los territorios, para así tener un acercamiento a los procesos de salud-enfermedad- atención de las comunidades. El mapeo colectivo es una técnica que permite visibilizar hábitos y espacios importantes donde transcurre la vida cotidiana de los y las diferentes actores a partir de la identificación y reconocimiento del barrio desde las representaciones sociales de los y las participantes del mismo

    Safe Areas for the Placement of Standard Shoulder Arthroscopy Portals: An Anatomical Study

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    The abundant vascular structures that surround the shoulder joint are complex and variable, complicating arthroscopy approaches. The aim of this study is to determine safe and risky areas around standard posterior and standard anterior portals, and accounting for the distribution of neurovascular structures of small and medium diameters that can lead to intra-articular bleeding during surgery. The standard posterior portal, and standard anterior portal were placed as described in the literature, and punch dissection was performed 2.5 cm around the trocar in situ. The arrangement of each identified structure was photographically documented and digitalized for each anatomic plane; the distance to the trocar and the diameter of each structure were measured. Based on each digitalized anatomic plane, safe and risky tissue areas were determined, and a clock face coordinate system was used to represent these areas. The safe area around the standard posterior portal was located between 11 and 1 o´clock for the left shoulder and 11 and 2 o´clock for the right shoulder. For the standard anterior portal, the safe area was located between 2 and 3 o´clock for the left shoulder and between 9 and 12 o´clock for the right shoulder. However, we did document a risk of injuring the cephalic vein 5 times, the axillary artery 3 times and the deltoid branch of the thoracoacromial artery once. This study reports quantitatively the total number of small diameter structures present in the two shoulder arthroscopic portals evaluated. The safe areas proposed in this study must be evaluated to propose new access points for performing arthroscopic procedures on the shoulder
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