125 research outputs found

    Big Data Approach for Secure Traffic Data Analytics using Hadoop

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    As the volume of traffic is increasing day by day, it gets difficult to store and process such huge sets of data using traditional software. A cluster of storage devices is needed to store such huge amounts of data and also a parallel computing model for analyzing those huge inputs of data. Hadoop is one such framework that provides reliable cluster of storage facility, which stores huge data in a distributed manner using a special file system, called Hadoop Distributed File System and provides efficient parallel processing feature through MapReduce framework. Using Map Reduce the filtered traffic data can be fetched easily, to provide end user with traffic analysis and giving useful predictions

    A REVIEW ON BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION

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    ABSTRACTIn this review article, bioanalytical methods are widely used to quantitate drugs and their metabolites in plasma matrices and the methods should beapplied to studies in areas of human clinical and nonhuman study. Bioanalytical method employed for the quantitative estimation of drugs and theirmetabolites in biological media and plays an important role in estimation and interpretation of bioequivalence, pharmacokinetic, and toxicokineticstudies. The major bioanalytical role is method development, method validation, and sample analysis. Every step in the method must be investigatedto decide the extent to which environment, matrix, or procedural variables can interfere the estimation of analyte in the matrix from the time of setup to the time of analysis. Techniques such as high pressure liquid chromatography (HPLC) and liquid chromatography coupled with double massspectrometry (LCMS-MS) can be used for the bioanalysis of drugs in body. Each of the instruments has its own merits and demerits. Chromatographicmethods are HPLC and gas chromatography have been mainly used for the bioanlysis of small/ large molecules, with LC/MS/MS. Linearity, accuracy,precision, selectivity, sensitivity, reproducibility, and stability are some of the regularly used parameters. In this review article, we are proposedto add some points regarding bioanalytical method development and validation parameter, beneficial to quality assurance to determine the drug,concentration and its metabolite.Keywords: Method development, Clinical and nonclinical study, Analyte, Validation of bioanlysis techniques, Validation parameter

    Password Authentication Key Exchange Mechanism using Identity Based System

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    In digital world various authentication techniques are used, password authentication is one of the traditional technique. Many improvements are made in password authentication techniques as only password authentication cannot withstand today?s attack. One of the password authentication technique is two-server password authentication. In two-server password-authenticated key exchange (PAKE) protocol, a client splits its password and stores two shares of its password in the two servers, respectively, and the two servers then cooperate to authenticate the client without knowing the password of the client. In case one server is compromised by an adversary, the password of the client is required to remain secure. Research work proposed two servers that stores two shares of identity password in encrypted format. The two shares of passwords will be stored in such a way that identity password will be reformed with the help of any user defined algorithm. Along with password authentication, here idea is to implement identity based on encryption technique to encrypt the documents and messages. Proposed system will prevent dictionary, shoulder surfing, and key logger attacks

    Meat Quality of Broiler Breast Fillets with White Striping and Woody Breast Muscle Myopathies

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    The global poultry industry has been faced with emerging broiler breast meat quality issues known as white striping and woody breast. Two experiments were conducted to evaluate effects of white striping and woody breast hardness on meat quality traits in broiler breast fillets. Birds were processed at 8 wk (Exp.1) and at 6 and 9 wk of age (Exp.2), whereas deboning was carried out at 4 and 2 h postmortem in Exp.1 and 2, respectively. Fillets were categorized as: normal for both white striping and woody breast (NORM); mild for white striping and woody breast (MILD); severe for white striping and mild for woody breast (WS); severe for woody breast and mild for white striping (WB); or severe for both white striping and woody breast (BOTH). Sarcomere length, gravimetric fragmentation index (GFI; Exp.1 only), marination uptake, cook loss, and Meullenet-Owens razor shear energy (MORSE) values on non-marinated and marinated fillets were assessed. Sarcomeres tended to be longer (P≤0.07) with increasing severity of white striping and woody breast in both experiments, but GFI was not impacted (P=0.49). Marinade uptake decreased (

    Access Constraint Of Intelligent System Over Wi-Fi Network - A Propose Plan

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    The growing ubiquity of public wireless network in university campus, corporate sector and other settings. The logical separation of user permission and security has become a matter of concern. To solve this problem, dual layer authentication is introduced in term of One Time Password (OTP) which is difficult to guess and not easily hacked or cracked by user. The concepts of time constraint mechanism for access control to limit the network usage and bandwidth utilization. Time constraint is different depending on the type of user. Another feature of this proposed paper is connection termination when system is idle for certain period of time

    An ETOP metric for Link Positions Routing in Wireless Network

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    Abstract Here we account for the fact that MAC protocols incorporate a finite number of transmission attempts per packet. The performance of a path depends not only on the number of the links on the path and the quality of its links, but also, on the relative positions of the links on the path based on this observation, we propose ETOP (Expected number of Transmissions On a Path), a path metric that captures the expected number of link layer transmissions required for reliable end-to-end packet delivery. We can analytically compute ETOP, which is not trivial, since ETOP is a noncommutative function of the link success probabilities. Although ETOP is a more involved metric, we show that the problem of computing paths with the minimum ETOP cost can be solved by a greedy algorithm. We will try to implement and evaluate a routing approach based on ETOP metric on wireless network

    Effect of Conventional and Microwave Tissue Processing Technique on DNA Integrity: A Comparative Molecular Analysis

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    BACKGROUND: Methods of diagnostic molecular biology are routinely applied on formalin-fixed, paraffin-embedded tissues processed via conventional method. Recently, there has been a growing interest to use microwave technology in histopathology laboratories to overcome the deficiencies of the conventional processing method. Thefore, this study was aimed to compare and analyze the quality and quantity of DNA obtained from tissues processed by conventional and microwave tissue processing techniques and to further ascertain the applicability of the latter for PCR (polymerase chain reaction based research).METHODS: Thirty fresh tissues of oral squamous cell carcinoma (OSCC) were included, and each sample was cut into two equivalent halves. One tissue half was processed by conventional manual method whereas the other half was processed using a domestic microwave oven. DNA was obtained from all the tissues which were then subjected to Polymerase chain reaction (PCR) to evaluate GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) gene expression.RESULTS: The results revealed better DNA yield from microwave processed tissue while the quality of the DNA was alike from both the techniques.CONCLUSION: On the basis of the results obtained, it can be concluded that DNA produced by microwave processed tissues was similar to that obtained by conventional processing technique in terms of quantity and quality. Thus, microwave processed tissue samples can be successfully used for further molecular studies and researches

    130 nm low power CMOS analog multiplier

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    Processing analog signal often involves analog multiplier and the multiplier is part of system on chip (SoC). Designing such system with a low power consumption is crucial nowadays. It is very important to increase the system battery lifetime. The design also must be smaller in size. In order to reduce the power consumption of the multiplier, an architecture that require smaller current must be designed and the approach is to use a design that is able to function at a low voltage supply. This project has designed the analog multiplier with a low power consumption using Silterra 130 nm Complementary Metal Oxide Semiconductor (CMOS) technology. A four quadrant technique is applied in the design. The scaling of transistor will help in reducing the size of the analog multiplier, and the proposed circuit architecture has produced a compact multiplier. Cadence electronic design automation (EDA) Tools is used to design the circuit. The schematic, layout, physical verification and parasitic extraction with post layout simulation are done to verify the multiplier circuit is functioning. The analog multiplier is operated with 1.2 V voltage supply and the power consumption is 98 μW. At 1 V, the power consumption is 32 μW. The total area for the design is 99 μm²

    Intraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study

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    Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk
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