The health belief model: How public health can address the misinformation crisis beyond COVID-19

Objectives: This paper proposes an intervention into health misinformation that relies upon the health belief model as a means to bridge the risks associated with health misinformation and the impact on individual health, beyond the current recommendations for fact checking and information literacy. Study design: This is a short theoretical paper. Methods: N/A. Results: N/A. Conclusions: Misinformation researchers and public health practitioners and communicators can benefit using the infrastructures afforded by public health offices to mobilize the health belief model as a site for misinformation education

Extreme Blazars Studied with Fermi-LAT and Suzaku: 1ES 0347-121 and Blazar Candidate HESS J1943+213

We report on our study of high-energy properties of two peculiar TeV emitters: the "extreme blazar" 1ES 0347-121 and the "extreme blazar candidate" HESS J1943+213 located near the Galactic Plane. Both objects are characterized by quiescent synchrotron emission with flat spectra extending up to the hard X-ray range, and both were reported to be missing GeV counterparts in the Fermi-LAT 2-year Source Catalog. We analyze a 4.5 year accumulation of the Fermi-LAT data, resulting in the detection of 1ES 0347-121 in the GeV band, as well as in improved upper limits for HESS J1943+213. We also present the analysis results of newly acquired Suzaku data for HESS J1943+213. The X-ray spectrum is well represented by a single power law extending up to 25 keV with photon index 2.00+/-0.02 and a moderate absorption in excess of the Galactic value, in agreement with previous X-ray observations. No short-term X-ray variability was found over the 80 ks duration of the Suzaku exposure. Under the blazar hypothesis, we modeled the spectral energy distributions of 1ES 0347-121 and HESS J1943+213, and derived constraints on the intergalactic magnetic field strength and source energetics. We conclude that although the classification of HESS J1943+213 has not yet been determined, the blazar hypothesis remains the most plausible option, since in particular the broad-band spectra of the two analyzed sources along with the source model parameters closely resemble each other, and the newly available WISE and UKIDSS data for HESS J1943+213 are consistent with the presence of an elliptical host at the distance of approximately ~600 Mpc.Comment: 10 pages, 7 figures, 3 tables. Accepted by Ap

New order parameters in the Potts model on a Cayley tree

For the $q-$state Potts model new order parameters projecting on a group of spins instead of a single spin are introduced. On a Cayley tree this allows the physical interpretation of the Potts model at noninteger values q of the number of states. The model can be solved recursively. This recursion exhibits chaotic behaviour changing qualitatively at critical values of $q_0$ . Using an additional order parameter belonging to a group of zero extrapolated size the additional ordering is related to a percolation problem. This percolation distinguishes different phases and explains the critical indices of percolation class occuring at the Peierls temperature.Comment: 16 pages TeX, 5 figures PostScrip

NASA Center for Climate Simulation (NCCS) Advanced Technology AT5 Virtualized Infiniband Report

The NCCS is part of the Computational and Information Sciences and Technology Office (CISTO) of Goddard Space Flight Center's (GSFC) Sciences and Exploration Directorate. The NCCS's mission is to enable scientists to increase their understanding of the Earth, the solar system, and the universe by supplying state-of-the-art high performance computing (HPC) solutions. To accomplish this mission, the NCCS (https://www.nccs.nasa.gov) provides high performance compute engines, mass storage, and network solutions to meet the specialized needs of the Earth and space science user communitie

The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis.

The recently completed European trial of interferon beta-1b (IFN beta -1b) in patients with secondary progressive multiple sclerosis (SP multiple sclerosis) has given an opportunity to assess the impact of treatment on cerebral atrophy using serial MRI. Unenhanced T-1-weighted brain imaging was acquired in a subgroup of 95 patients from five of the European centres; imaging was performed at 6-month intervals from month 0 to month 36. A blinded observer measured cerebral volume on four contiguous 5 mm cerebral hemisphere slices at each time point, using an algorithm with a high level of reproducibility and automation. There was a significant and progressive reduction in cerebral volume in both placebo and treated groups, with a mean reduction of 3.9 and 2.9%, respectively, by month 36 (P = 0.34 between groups). Exploratory subgroup analyses indicated that patients without gadolinium (Gd) enhancement at the baseline had a greater reduction of cerebral volume in the placebo group (mean reduction at month 36: placebo 5.1%, IFN beta -1b 1.8%, P < 0.05) whereas those with Gd-enhancing lesions showed a trend to greater reduction of cerebral volume if the patient was on IFN<beta>-1b (placebo 2.6%, IFN beta -1b, 3.7%; P > 0.05). These results are consistent with ongoing tissue loss in both arms of this study of secondary progressive multiple sclerosis. This finding is concordant with previous observations that disease progression, although delayed, is not halted by IFN beta. The different pattern seen in patients with and without baseline gadolinium enhancement suggests that part of the cerebral volume reduction observed in IFN beta -treated patients may be due to the anti-inflammatory/antioedematous effect of the drug. Longer periods of observation and larger groups of patients may be needed to detect the effects of treatment on cerebral atrophy in this population of patients with advanced disease

A search for VHE counterparts of Galactic Fermi bright sources and MeV to TeV spectral characterization

Very high-energy (VHE; E>100 GeV) gamma-rays have been detected from a wide range of astronomical objects, such as pulsar wind nebulae (PWNe), supernova remnants (SNRs), giant molecular clouds, gamma-ray binaries, the Galactic Center, active galactic nuclei (AGN), radio galaxies, starburst galaxies, and possibly star-forming regions as well. At lower energies, observations using the Large Area Telescope (LAT) onboard Fermi provide a rich set of data which can be used to study the behavior of cosmic accelerators in the MeV to TeV energy bands. In particular, the improved angular resolution of current telescopes in both bands compared to previous instruments significantly reduces source confusion and facilitates the identification of associated counterparts at lower energies. In this paper, a comprehensive search for VHE gamma-ray sources which are spatially coincident with Galactic Fermi/LAT bright sources is performed, and the available MeV to TeV spectra of coincident sources are compared. It is found that bright LAT GeV sources are correlated with TeV sources, in contrast to previous studies using EGRET data. Moreover, a single spectral component seems unable to describe the MeV to TeV spectra of many coincident GeV/TeV sources. It has been suggested that gamma-ray pulsars may be accompanied by VHE gamma-ray emitting nebulae, a hypothesis that can be tested with VHE observations of these pulsars.Comment: Astronomy and Astrophysics, in press, 17 pages, 12 figures, 5 table

Involvement of patients or their representatives in quality management functions in EU hospitals:implementation and impact on patient-centred care strategies

OBJECTIVE: The objective of this study was to describe the involvement of patients or their representatives in quality management (QM) functions and to assess associations between levels of involvement and the implementation of patient-centred care strategies. DESIGN: A cross-sectional, multilevel STUDY DESIGN: that surveyed quality managers and department heads and data from an organizational audit. SETTING: Randomly selected hospitals (n = 74) from seven European countries (The Czech Republic, France, Germany, Poland, Portugal, Spain and Turkey). PARTICIPANTS: Hospital quality managers (n = 74) and heads of clinical departments (n = 262) in charge of four patient pathways (acute myocardial infarction, stroke, hip fracture and deliveries) participated in the data collection between May 2011 and February 2012. MAIN OUTCOME MEASURES: Four items reflecting essential patient-centred care strategies based on an on-site hospital visit: (1) formal survey seeking views of patients and carers, (2) written policies on patients' rights, (3) patient information literature including guidelines and (4) fact sheets for post-discharge care. The main predictors were patient involvement in QM at the (i) hospital level and (ii) pathway level. RESULTS: Current levels of involving patients and their representatives in QM functions in European hospitals are low at hospital level (mean score 1.6 on a scale of 0 to 5, SD 0.7), but even lower at departmental level (mean 0.6, SD 0.7). We did not detect associations between levels of involving patients and their representatives in QM functions and the implementation of patient-centred care strategies; however, the smallest hospitals were more likely to have implemented patient-centred care strategies. CONCLUSIONS: There is insufficient evidence that involving patients and their representatives in QM leads to establishing or implementing strategies and procedures that facilitate patient-centred care; however, lack of evidence should not be interpreted as evidence of no effect

Investigating the widely held belief that men and women with learning disabilities receive poor quality healthcare when admitted to hospital: a single-site study of 30-day readmission rates.

BACKGROUND: This study aims to use 30-day readmission rates to investigate the presumption that men and women with learning disabilities (LDs, known internationally as intellectual disabilities) receive poorer quality hospital care than their non-disabled peers. METHOD: A 12-month retrospective audit was conducted using Hospital Episode Statistics (HES) at a single acute hospital in the East of England. This identified all in-patient admissions; admissions where the person concerned was recognised as having a LD; and all emergency readmissions within 30 days of discharge. Additionally, the healthcare records of all patients identified as having a LD and readmitted within 30 days as a medical emergency were examined in order to determine whether or not these readmissions were potentially preventable. RESULTS: Over the study period, a total of 66 870 adults were admitted as in-patients, among whom 7408 were readmitted as medical emergencies within 30 days of discharge: a readmission rate of 11%. Of these 66 870 patients, 256 were identified as having a LD, with 32 of them experiencing at least one emergency readmission within 30 days: a readmission rate of 13%. When examined, the healthcare records pertaining to these 32 patients who had a total of 39 unique 30-day readmissions revealed that 69% (n = 26) of these readmissions were potentially preventable. CONCLUSION: Although overall readmission rates were similar for patients with LDs and those from the general population, patients with LDs had a much higher rate of potentially preventable readmissions when compared to a general population estimate from van Walraven et al. This suggests that there is still work to be done to ensure that this patient population receives hospital care that is both safe and of high quality.This research was funded by a grant from the Addenbrooke's Charitable Trust (CK), while the preparation of this paper was funded by the Health Foundation (AH, MR) and the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care East of England (AH, MR, AW) at Cambridgeshire and Peterborough NHS Foundation Trust.This is the author accepted manuscript. The final version is available from Wiley via http://dx.doi.org/10.1111/jir.1219