Experimental Demonstration of Quantum Fully Homomorphic Encryption with Application in a Two-Party Secure Protocol

A fully homomorphic encryption system hides data from unauthorized parties while still allowing them to perform computations on the encrypted data. Aside from the straightforward benefit of allowing users to delegate computations to a more powerful server without revealing their inputs, a fully homomorphic cryptosystem can be used as a building block in the construction of a number of crypt

Experimental demonstration of quantum fully homomorphic encryption with application in a two-party secure protocol

A fully homomorphic encryption system hides data from unauthorized parties, while still allowing them to perform computations on the encrypted data. Aside from the straightforward benefit of allowing users to delegate computations to a more powerful server without revealing their inputs, a fully homomorphic cryptosystem can be used as a building block in the construction of a number of cryptographic functionalities. Designing such a scheme remained an open problem until 2009, decades after the idea was first conceived, and the past few years have seen the generalization of this functionality to the world of quantum machines. Quantum schemes prior to the one implemented here were able to replicate some features in particular use-cases often associated with homomorphic encryption but lacked other crucial properties, for example, relying on continual interaction to perform a computation or leaking information about the encrypted data. We present the first experimental realisation of a quantum fully homomorphic encryption scheme. We further present a toy two-party secure computation task enabled by our scheme. Finally, as part of our implementation, we also demonstrate a post-selective two-qubit linear optical controlled-phase gate with a much higher post-selection success probability (1/2) when compared to alternate implementations, e.g. with post-selective controlled-Z or controlled-X gates (1/9).</p

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

Central corneal thickness (CCT) is a highly heritable trait associated with complex eye diseases such as keratoconus and glaucoma. We perform a genome-wide association meta-analysis of CCT and identify 19 novel regions. In addition to adding support for known connective tissue-related pathways, pathway analyses uncover previously unreported gene sets. Remarkably, >20% of the CCT-loci are near or within Mendelian disorder genes. These included FBN1, ADAMTS2 and TGFB2 which associate with connective tissue disorders (Marfan, Ehlers-Danlos and Loeys-Dietz syndromes), and the LUM-DCN-KERA gene complex involved in myopia, corneal dystrophies and cornea plana. Using index CCT-increasing variants, we find a significant inverse correlation in effect sizes between CCT and keratoconus (r =-0.62, P = 5.30 × 10-5) but not between CCT and primary open-angle glaucoma (r =-0.17, P = 0.2). Our findings provide evidence for shared genetic influences between CCT and keratoconus, and implicate candidate genes acting in collagen and extracellular matrix regulation

Correlates, facilitators and barriers of healthy eating among primary care patients with prediabetes in singapore-A mixed methods approach

10.3390/nu11051014Nutrients115101

Correlates, facilitators and barriers of physical activity among primary care patients with prediabetes in Singapore - A mixed methods approach

10.1186/s12889-019-7969-5BMC Public Health201

Erratum to: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases (Nature Communications, (2018), 9, 1, (1864), 10.1038/s41467-018-03646-6)

10.1038/s41467-018-07819-1Nature Communications10115