172 research outputs found
Apprentice pay in Britain, Germany and Switzerland: Institutions, market forces and market power
This is the accepted version of the original publication in the European Journal of Industrial Relations, which is available online at http://ejd.sagepub.com/content/19/3/201.The pay of metalworking apprentices is high in Britain, middling in Germany and low in Switzerland. We analyse these differences using fieldwork evidence and survey data, drawing on both economic and institutionalist theories. Several institutional attributes influence apprentice pay, partly by affecting supply and demand in markets for training places. Institutional support for apprenticeship training appears to involve important complementarities in both Germany and Switzerland, in contrast to Britain’s less coherent and more market-driven approach.We thank the Hans-Böckler-Stiftung, Anglo-German Foundation, SKOPE (Oxford), the Swiss federal government (OPET/SERI) and WZB (Berlin) for financial support
On the Tort of Light Pollution
光污染是现代社会的新公害。光污染,在英美被称为“干扰光”,在日本则称其为“光害”,在德国则被视为“不可量物”的一种,而在我国,有学者援用“噪音”的说法,将其称“噪光”。光污染是指因不当使用人为照明或其它设备造成光的入侵而引起的不良影响。对于光污染,根据不同的标准可以作不同的分类。例如根据光污染发生时间的不同,可以将光污染分为昼光光污染和夜光光污染。国际上一般将光污染分成三类,即白亮污染、人工白昼和彩光污染。光污染对环境、生物和人都危害甚巨。 我国现行涉及光污染侵权的立法主要体现在宪法、民法通则、物权法、侵权责任法、环境保护法和地方立法之中。我国现行涉及光污染侵权的立法,无论是中央立法还是地方...Light pollution is a new form of environment pollution in modern society. It was called "interference of light" in Britain and America. It was called "light nuisance" in Japan. In Germany, light pollution is considered to be a kind of "non-amount of matter". Light pollution is due to the improper use of artificial lighting and the adverse effects caused by the invasion of light. According to the d...学位:法律硕士院系专业:法学院法律系_法律硕士(JM)学号:1302009115036
Inferring statistics of planet populations by means of automated microlensing searches
(abridged) The study of other worlds is key to understanding our own, and not
only provides clues to the origin of our civilization, but also looks into its
future. Rather than in identifying nearby systems and learning about their
individual properties, the main value of the technique of gravitational
microlensing is in obtaining the statistics of planetary populations within the
Milky Way and beyond. Only the complementarity of different techniques
currently employed promises to yield a complete picture of planet formation
that has sufficient predictive power to let us understand how habitable worlds
like ours evolve, and how abundant such systems are in the Universe. A
cooperative three-step strategy of survey, follow-up, and anomaly monitoring of
microlensing targets, realized by means of an automated expert system and a
network of ground-based telescopes is ready right now to be used to obtain a
first census of cool planets with masses reaching even below that of Earth
orbiting K and M dwarfs in two distinct stellar populations, namely the
Galactic bulge and disk. The hunt for extra-solar planets acts as a principal
science driver for time-domain astronomy with robotic-telescope networks
adopting fully-automated strategies. Several initiatives, both into facilities
as well as into advanced software and strategies, are supposed to see the
capabilities of gravitational microlensing programmes step-wise increasing over
the next 10 years. New opportunities will show up with high-precision
astrometry becoming available and studying the abundance of planets around
stars in neighbouring galaxies becoming possible. Finally, we should not miss
out on sharing the vision with the general public, and make its realization to
profit not only the scientists but all the wider society.Comment: 10 pages in PDF format. White paper submitted to ESA's Exo-Planet
Roadmap Advisory Team (EPR-AT); typos corrected. The embedded figures are
available from the author on request. See also "Towards A Census of
Earth-mass Exo-planets with Gravitational Microlensing" by J.P. Beaulieu, E.
Kerins, S. Mao et al. (arXiv:0808.0005
I. Flux and color variations of the quadruply imaged quasar HE 0435-1223
aims: We present VRi photometric observations of the quadruply imaged quasar
HE 0435-1223, carried out with the Danish 1.54m telescope at the La Silla
Observatory. Our aim was to monitor and study the magnitudes and colors of each
lensed component as a function of time. methods: We monitored the object during
two seasons (2008 and 2009) in the VRi spectral bands, and reduced the data
with two independent techniques: difference imaging and PSF (Point Spread
Function) fitting.results: Between these two seasons, our results show an
evident decrease in flux by ~0.2-0.4 magnitudes of the four lensed components
in the three filters. We also found a significant increase (~0.05-0.015) in
their V-R and R-i color indices. conclusions: These flux and color variations
are very likely caused by intrinsic variations of the quasar between the
observed epochs. Microlensing effects probably also affect the brightest "A"
lensed component.Comment: 10 pages, 8 figure
Frequency-modulated electromagnetic neural stimulation (FREMS) as a treatment for symptomatic diabetic neuropathy: results from a double-blind, randomised, multicentre, long-term, placebo-controlled clinical trial
AIMS/HYPOTHESIS: The aim was to evaluate the efficacy and safety of
transcutaneous frequency-modulated electromagnetic neural stimulation (frequency
rhythmic electrical modulation system, FREMS) as a treatment for symptomatic
peripheral neuropathy in patients with diabetes mellitus.
METHODS: This was a double-blind, randomised, multicentre, parallel-group study
of three series, each of ten treatment sessions of FREMS or placebo administered
within 3 weeks, 3 months apart, with an overall follow-up of about 51 weeks. The
primary endpoint was the change in nerve conduction velocity (NCV) of deep
peroneal, tibial and sural nerves. Secondary endpoints included the effects of
treatment on pain, tactile, thermal and vibration sensations. Patients eligible
to participate were aged 18-75 years with diabetes for ≥ 1 year, HbA(1c) <11.0%
(97 mmol/mol), with symptomatic diabetic polyneuropathy at the lower extremities
(i.e. abnormal amplitude, latency or NCV of either tibial, deep peroneal or sural
nerve, but with an evocable potential and measurable NCV of the sural nerve), a
Michigan Diabetes Neuropathy Score ≥ 7 and on a stable dose of medications for
diabetic neuropathy in the month prior to enrolment. Data were collected in an
outpatient setting. Participants were allocated to the FREMS or placebo arm (1:1
ratio) according to a sequence generated by a computer random number generator,
without block or stratification factors. Investigators digitised patients' date
of birth and site number into an interactive voice recording system to obtain the
assigned treatment. Participants, investigators conducting the trial, or people
assessing the outcomes were blinded to group assignment.
RESULTS: Patients (n = 110) with symptomatic neuropathy were randomised to FREMS
(n = 54) or placebo (n = 56). In the intention-to-treat population (50 FREMS, 51
placebo), changes in NCV of the three examined nerves were not different between
FREMS and placebo (deep peroneal [means ± SE]: 0.74 ± 0.71 vs 0.06 ± 1.38 m/s;
tibial: 2.08 ± 0.84 vs 0.61 ± 0.43 m/s; and sural: 0.80 ± 1.08 vs -0.91 ± 1.13
m/s; FREMS vs placebo, respectively). FREMS induced a significant reduction in
day and night pain as measured by a visual analogue scale immediately after each
treatment session, although this beneficial effect was no longer measurable 3
months after treatment. Compared with the placebo group, in the FREMS group the
cold sensation threshold was significantly improved, while non-significant
differences were observed in the vibration and warm sensation thresholds. No
relevant side effects were recorded during the study.
CONCLUSIONS/INTERPRETATION: FREMS proved to be a safe treatment for symptomatic
diabetic neuropathy, with immediate, although transient, reduction in pain, and
no effect on NCV.
TRIAL REGISTRATION: ClinicalTrials.gov NCT01628627.
FUNDING: The clinical trial was sponsored by Lorenz Biotech (Medolla, Italy),
lately Lorenz Lifetech (Ozzano dell'Emilia, Italy)
Differential Actions of Chlorhexidine on the Cell Wall of Bacillus subtilis and Escherichia coli
Chlorhexidine is a chlorinated phenolic disinfectant used commonly in mouthwash for its action against bacteria. However, a comparative study of the action of chlorhexidine on the cell morphology of Gram-positive and Gram-negative bacteria is lacking. In this study, the actions of chlorhexidine on the cell morphology were identified with the aids of electron microscopy. After exposure to chlorhexidine, numerous spots of indentation on the cell wall were found in both Bacillus subtilis and Escherichia coli. The number of indentation spots increased with time of incubation and increasing chlorhexidine concentration. Interestingly, the dented spots found in B. subtilis appeared mainly at the hemispherical caps of the cells, while in E. coli the dented spots were found all over the cells. After being exposed to chlorhexidine for a prolonged period, leakage of cellular contents and subsequent ghost cells were observed, especially from B subtilis. By using 2-D gel/MS-MS analysis, five proteins related to purine nucleoside interconversion and metabolism were preferentially induced in the cell wall of E. coli, while three proteins related to stress response and four others in amino acid biosynthesis were up-regulated in the cell wall materials of B. subtilis. The localized morphological damages together with the biochemical and protein analysis of the chlorhexidine-treated cells suggest that chlorhexidine may act on the differentially distributed lipids in the cell membranes/wall of B. subtilis and E. coli
Genes but Not Genomes Reveal Bacterial Domestication of Lactococcus Lactis
BACKGROUND: The population structure and diversity of Lactococcus lactis subsp. lactis, a major industrial bacterium involved in milk fermentation, was determined at both gene and genome level. Seventy-six lactococcal isolates of various origins were studied by different genotyping methods and thirty-six strains displaying unique macrorestriction fingerprints were analyzed by a new multilocus sequence typing (MLST) scheme. This gene-based analysis was compared to genomic characteristics determined by pulsed-field gel electrophoresis (PFGE). METHODOLOGY/PRINCIPAL FINDINGS: The MLST analysis revealed that L. lactis subsp. lactis is essentially clonal with infrequent intra- and intergenic recombination; also, despite its taxonomical classification as a subspecies, it displays a genetic diversity as substantial as that within several other bacterial species. Genome-based analysis revealed a genome size variability of 20%, a value typical of bacteria inhabiting different ecological niches, and that suggests a large pan-genome for this subspecies. However, the genomic characteristics (macrorestriction pattern, genome or chromosome size, plasmid content) did not correlate to the MLST-based phylogeny, with strains from the same sequence type (ST) differing by up to 230 kb in genome size. CONCLUSION/SIGNIFICANCE: The gene-based phylogeny was not fully consistent with the traditional classification into dairy and non-dairy strains but supported a new classification based on ecological separation between "environmental" strains, the main contributors to the genetic diversity within the subspecies, and "domesticated" strains, subject to recent genetic bottlenecks. Comparison between gene- and genome-based analyses revealed little relationship between core and dispensable genome phylogenies, indicating that clonal diversification and phenotypic variability of the "domesticated" strains essentially arose through substantial genomic flux within the dispensable genome
Is the meiofauna a good indicator for climate change and anthropogenic impacts?
Our planet is changing, and one of the most pressing challenges facing the scientific community revolves around understanding how ecological communities respond to global changes. From coastal to deep-sea ecosystems, ecologists are exploring new areas of research to find model organisms that help predict the future of life on our planet. Among the different categories of organisms, meiofauna offer several advantages for the study of marine benthic ecosystems. This paper reviews the advances in the study of meiofauna with regard to climate change and anthropogenic impacts. Four taxonomic groups are valuable for predicting global changes: foraminifers (especially calcareous forms), nematodes, copepods and ostracods. Environmental variables are fundamental in the interpretation of meiofaunal patterns and multistressor experiments are more informative than single stressor ones, revealing complex ecological and biological interactions. Global change has a general negative effect on meiofauna, with important consequences on benthic food webs. However, some meiofaunal species can be favoured by the extreme conditions induced by global change, as they can exhibit remarkable physiological adaptations. This review highlights the need to incorporate studies on taxonomy, genetics and function of meiofaunal taxa into global change impact research
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