Multifractal properties of elementary cellular automata in a discrete wavelet approach of MF-DFA

In 2005, Nagler and Claussen (Phys. Rev. E 71 (2005) 067103) investigated the time series of the elementary cellular automata (ECA) for possible (multi)fractal behavior. They eliminated the polynomial background at^b through the direct fitting of the polynomial coefficients a and b. We here reconsider their work eliminating the polynomial trend by means of the multifractal-based detrended fluctuation analysis (MF-DFA) in which the wavelet multiresolution property is employed to filter out the trend in a more speedy way than the direct polynomial fitting and also with respect to the wavelet transform modulus maxima (WTMM) procedure. In the algorithm, the discrete fast wavelet transform is used to calculate the trend as a local feature that enters the so-called details signal. We illustrate our result for three representative ECA rules: 90, 105, and 150. We confirm their multifractal behavior and provide our results for the scaling parametersComment: 8 pages, 5 figures, 21 reference

Multifractal properties of elementary cellular automata in a discrete wavelet approach of MF-DFA

In 2005, Nagler and Claussen (Phys. Rev. E 71 (2005) 067103) investigated the time series of the elementary cellular automata (ECA) for possible (multi)fractal behavior. They eliminated the polynomial background at^b through the direct fitting of the polynomial coefficients a and b. We here reconsider their work eliminating the polynomial trend by means of the multifractal-based detrended fluctuation analysis (MF-DFA) in which the wavelet multiresolution property is employed to filter out the trend in a more speedy way than the direct polynomial fitting and also with respect to the wavelet transform modulus maxima (WTMM) procedure. In the algorithm, the discrete fast wavelet transform is used to calculate the trend as a local feature that enters the so-called details signal. We illustrate our result for three representative ECA rules: 90, 105, and 150. We confirm their multifractal behavior and provide our results for the scaling parametersComment: 8 pages, 5 figures, 21 reference

Supersymmetric methods in the traveling variable: inside neurons and at the brain scale

We apply the mathematical technique of factorization of differential operators to two different problems. First we review our results related to the supersymmetry of the Montroll kinks moving onto the microtubule walls as well as mentioning the sine-Gordon model for the microtubule nonlinear excitations. Second, we find analytic expressions for a class of one-parameter solutions of a sort of diffusion equation of Bessel type that is obtained by supersymmetry from the homogeneous form of a simple damped wave equations derived in the works of P.A. Robinson and collaborators for the corticothalamic system. We also present a possible interpretation of the diffusion equation in the brain contextComment: 14 pages, 1 figur

Levels of insulin and HOMA-IR in adolescents in Saltillo, Coahuila, Mexico

An alarming rise of obesity in adolescents has been observed, placing them at risk of developing resistance to insulin (IR) and its adverse metabolic consequences such as diabetes mellitus type 2 (DM2), metabolic syndrome and cardiovascular disease. Objective: To know the prevalence of obesity, and the levels of glucose, insulin and HOMA-IR and its association with the BMIz, waist circumference and the pubertal stage in a random sample of adolescents. Materials and methods: 292 adolescents between 12 and 15 years (152 female and 140 male), whose anthropometric measurements (weight, height and waist circumference) were taken, body mass index calculated and Z-score determined. Blood glucose and insulin levels were evaluated from a sample of blood and their HOMA-IR was determined. Results: The results showed that 32.5% were obese, 22.3% were overweight and 23.6% showed adolescent central obesity. Glucose levels (p = 0.016), insulin (p = 0.0001) and HOMA-IR (p = 0.0001) showed significant differences in the group with obesity. Values of the three parameters were increased with the stage of puberty. We found significant differences in the levels of glucose (p = 0.0388), insulin (p = 0.0005) and HOMA-IR (p = 0.0001) between the prepubertal and postpubertal stages

Uso de ultrasonidos para la predicción del valor de la canal en terneros de raza asturiana de los valles

In order to improve the meat yield in Asturiana beef cattle, a series of in vivo selection criteria for carcasses are proposed. This information can be obtained by means of ultrasound imaging. The implementation of this technique involves two stages. The first, to put in point the technique and acquire experience in its application, will be developed in the Selection Center at Posada of Llanera (Asturias) with the animals under growth test. The second will be permormed under field conditions, in commercial feedlots and its purpose will be to check whether the taken measurements in the living animal are reasonably correlated with those obtained directly on the carcass. Some results of the first stage are shown.Para mejorar el rendimiento carnicero de la raza Asturiana de los Valles, se pretende incorporar criterios de valoración de canales in vivo en el programa de mejora de dicha raza. Esta información puede obtenerse por métodos ultrasonográficos. La aplicación de la técnica se plantea en dos fases. Una para poner a punto la técnica y adquirir experiencia en su aplicación, se desarrollará en el Centro de Selección de Posada de Llanera (Asturias) con los animales sometidos a testaje. Otra, en condiciones de campo, en cebaderos comerciales para comprobar si las medidas tomadas en el animal vivo están razonablemente correlacionadas con las obtenidas directamente en la canal. Se exponen algunos resultados de la primera fase

Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides

Phosphorothioates (PS) have proven their effectiveness in the area of therapeutic oligonucleotides with applications spanning from cancer treatment to neurodegenerative disorders. Initially, PS substitution was introduced for the antisense oligonucleotides (PS ASOs) because it confers an increased nuclease resistance meanwhile ameliorates cellular uptake and in-vivo bioavailability. Thus, PS oligonucleotides have been elevated to a fundamental asset in the realm of gene silencing therapeutic methodologies. But, despite their wide use, little is known on the possibly different structural changes PS-substitutions may provoke in DNA·RNA hybrids. Additionally, scarce information and significant controversy exists on the role of phosphorothioate chirality in modulating PS properties. Here, through comprehensive computational investigations and experimental measurements, we shed light on the impact of PS chirality in DNA-based antisense oligonucleotides; how the different phosphorothioate diastereomers impact DNA topology, stability and flexibility to ultimately disclose pro-Sp S and pro-Rp S roles at the catalytic core of DNA Exonuclease and Human Ribonuclease H; two major obstacles in ASOs-based therapies. Altogether, our results provide full-atom and mechanistic insights on the structural aberrations PS-substitutions provoke and explain the origin of nuclease resistance PS-linkages confer to DNA·RNA hybrids; crucial information to improve current ASOs-based therapies.© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research

Evaluación de los escenarios de peligro hidrológico en los ríos Colca-Majes-Camaná

"El día 18 de junio del presente año se produjo uno de los más grandes deslizamientos de tierra en el sur del Perú ocasionado por un sismo. Dicho deslizamiento ocasionó el embalse del río Colca en el distrito de Achoma de la provincia de Carabaya-Arequipa. Mediante Decreto Supremo N° 111-2020-PCM se emite la declaratoria de estado de emergencia a los distritos de Achoma, Yanque e Ichupampa por desastre a consecuencia de deslizamientos de tierra".--Introducción

The Close AGN Reference Survey (CARS): Locating the [O III] wing component in luminous local Type 1 AGN

Context. The strong asymmetry in the optical [O III] λ5007 emission line is one of the best signatures of active galactic nuclei (AGN) driven warm (∼104 K) ionized gas outflows on host galaxy scales. While large spectroscopic surveys such as the sloan digital sky survey (SDSS) have characterized the kinematics of [O III] for large samples of AGN, estimating the associated energetics requires spatially resolving these outflows with, for example, integral field unit (IFU) studies. Aims. As part of the Close AGN Reference Survey, we obtained spatially resolved IFU spectroscopy for a representative sample of 39 luminous type 1 AGN at 0.01 < z < 0.06 with the multi unit spectroscopic explorer and the visible multi object spectrograph IFUs at the very large telescope to infer the spatial location of the ionized gas outflows. Methods. We compared the 2D light distributions of the [O III] wing to that of the Hβ broad emission line region, a classical point source (PSF). We then used the PSF to distinguish between the unresolved and resolved [O III] wing emission. We further determined its location using spectro-astrometry for the point-like sources. Results. The [O III] wing is spatially unresolved in 23 out of the 36 AGN with > 80% of the flux associated with a point-like source. We measured < 100 pc offsets in the spatial location of the outflow from the AGN nucleus using the spectro-astrometry technique for these sources. For the other 13 AGN, the [O III] wing emission is resolved and possibly extended on several kiloparsec scales. Conclusions. We conclude that [O III] wing emission can be compact or extended in an unbiased luminous AGN sample, where both cases are likely to appear. Electron density in the compact [O III] wing regions (median ne ∼ 1900 cm−3) is nearly a magnitude higher than in the extended ones (median ne ∼ 500 cm−3). The presence of spatially extended and compact [O III] wing emission is unrelated to the AGN bolometric luminosity and to inclination effects, which means other features such as time delays, or mechanical feedback (radio jets) may shape the ionized gas outflow properties

Design and construction of the MicroBooNE Cosmic Ray Tagger system

The MicroBooNE detector utilizes a liquid argon time projection chamber (LArTPC) with an 85 t active mass to study neutrino interactions along the Booster Neutrino Beam (BNB) at Fermilab. With a deployment location near ground level, the detector records many cosmic muon tracks in each beam-related detector trigger that can be misidentified as signals of interest. To reduce these cosmogenic backgrounds, we have designed and constructed a TPC-external Cosmic Ray Tagger (CRT). This sub-system was developed by the Laboratory for High Energy Physics (LHEP), Albert Einstein center for fundamental physics, University of Bern. The system utilizes plastic scintillation modules to provide precise time and position information for TPC-traversing particles. Successful matching of TPC tracks and CRT data will allow us to reduce cosmogenic background and better characterize the light collection system and LArTPC data using cosmic muons. In this paper we describe the design and installation of the MicroBooNE CRT system and provide an overview of a series of tests done to verify the proper operation of the system and its components during installation, commissioning, and physics data-taking

Dense stellar clump formation driven by strong quasar winds in the FIRE cosmological hydrodynamic simulations

We investigate the formation of dense stellar clumps in a suite of high-resolution cosmological zoom-in simulations of a massive, star forming galaxy at $z \sim 2$ under the presence of strong quasar winds. Our simulations include multi-phase ISM physics from the Feedback In Realistic Environments (FIRE) project and a novel implementation of hyper-refined accretion disk winds. We show that powerful quasar winds can have a global negative impact on galaxy growth while in the strongest cases triggering the formation of an off-center clump with stellar mass ${\rm M}_{\star}\sim 10^{7}\,{\rm M}_{\odot}$, effective radius ${\rm R}_{\rm 1/2\,\rm Clump}\sim 20\,{\rm pc}$, and surface density $\Sigma_{\star} \sim 10^{4}\,{\rm M}_{\odot}\,{\rm pc}^{-2}$. The clump progenitor gas cloud is originally not star-forming, but strong ram pressure gradients driven by the quasar winds (orders of magnitude stronger than experienced in the absence of winds) lead to rapid compression and subsequent conversion of gas into stars at densities much higher than the average density of star-forming gas. The AGN-triggered star-forming clump reaches ${\rm SFR} \sim 50\,{\rm M}_{\odot}\,{\rm yr}^{-1}$ and $\Sigma_{\rm SFR} \sim 10^{4}\,{\rm M}_{\odot}\,{\rm yr}^{-1}\,{\rm kpc}^{-2}$, converting most of the progenitor gas cloud into stars in $\sim$2\,Myr, significantly faster than its initial free-fall time and with stellar feedback unable to stop star formation. In contrast, the same gas cloud in the absence of quasar winds forms stars over a much longer period of time ($\sim$35\,Myr), at lower densities, and losing spatial coherency. The presence of young, ultra-dense, gravitationally bound stellar clumps in recently quenched galaxies could thus indicate local positive feedback acting alongside the strong negative impact of powerful quasar winds, providing a plausible formation scenario for globular clusters.Comment: 14 pages, 12 figure