Light scattering from cold rolled aluminum surfaces

We present experimental light scattering measurements from aluminum surfaces obtained by cold rolling. We show that our results are consistent with a scale invariant description of the roughness of these surfaces. The roughness parameters that we obtain from the light scattering experiment are consistent with those obtained from Atomic Force Microscopy measurements

Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential

Ajudes rebudes: Marie Curie Career Integration Grant; Dexeus Foundation for Women's Health Research; i Contratos Ramón y CajalCD11c is an α integrin classically employed to define myeloid dendritic cells. Although there is little information about CD11c expression on human T cells, mouse models have shown an association of CD11c expression with functionally relevant T cell subsets. In the context of genital tract infection, we have previously observed increased expression of CD11c in circulating T cells from mice and women. Microarray analyses of activated effector T cells expressing CD11c derived from naïve mice demonstrated enrichment for natural killer (NK) associated genes. Here we find that murine CD11c+ T cells analyzed by flow cytometry display markers associated with non-conventional T cell subsets, including γδ T cells and invariant natural killer T (iNKT) cells. However, in women, only γδ T cells and CD8+ T cells were enriched within the CD11c fraction of blood and cervical tissue. These CD11c+ cells were highly activated and had greater interferon (IFN)-γ secretory capacity than CD11c- T cells. Furthermore, circulating CD11c+ T cells were associated with the expression of multiple adhesion molecules in women, suggesting that these cells have high tissue homing potential. These data suggest that CD11c expression distinguishes a population of circulating T cells during bacterial infection with innate capacity and mucosal homing potential

Etude experimentale et analyse microscopique de la diffusion elastique de nucleons de basse energie

SIGLEAvailable from CEN Saclay, Service de Documentation, 91191 - Gif-sur-Yvette Cedex (France) / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

Étude par rayonnement synchrotron de moules à alvéoles de La Tène finale trouvés à Villeneuve-St-Germain et au Mont-Beuvray

At the end of the Celtic era (first century BC), one finds on many sites different moulds in baked clay plates. The use of these moulds is unknown and a new examination was desirable. Synchrotron Radiation X-ray fluorescence analysis of the holes was realized to caracterize the elements deposited inside. moulds is not enough to prove the reality of coins production on this site.II a paru nécessaire de réexaminer des moules à alvéoles de section circulaire ou rectangulaire et d'en caractériser le contenu ; l'usage de ces moules reste en effet mystérieux. Deux séries de moules ont été étudiées, l'une en provenance du site de Villeneuve-St-Germain, l'autre de celui du Mont-Beuvray. L'analyse par fluorescence X montre un enrichissement des parois des alvéoles en cuivre, argent, or et plomb pour les moules de Villeneuve-St-Germain. De même on note un enrichissement en nickel, cuivre, arsenic, or et plomb pour les moules du Mont-Beuvray. Il semble raisonnable d'associer ces derniers moules à des ateliers «d'orfèvres» plutôt qu'à une fabrication monétaire, même si les enrichissements correspondent à des alliages monétaires.Chevallier Pierre, Legrand François, Gruel K., Brissaud Ivan, Tarrats Annie. Étude par rayonnement synchrotron de moules à alvéoles de La Tène finale trouvés à Villeneuve-St-Germain et au Mont-Beuvray. In: Revue d'Archéométrie, n°17, 1993. pp. 75-88

A two-dimensional model for sensitivity studies on laser-generated ultrasound

International audienceA two-dimensional simulation model is presented that, within certain limitative assumptions, calculates the displacements generated by the absorption of a laser pulse in the thermoelastic regime. This model solves the Christoffel equations in an axisymmetrical configuration (the laser excitation is supposed to have a gaussian surface profile) over an infinite plate of finite thickness presenting a cylindrical orthotropy. The resolution of these Christoffel equations is made in the Laplace and Hankel spaces. After the validation of this model by the confrontation of its predictions to experimental data, we present two applications of it concerning the related temporal convolutions occurring to produce the longitudinal precursor

Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential

Ajudes rebudes: Marie Curie Career Integration Grant; Dexeus Foundation for Women's Health Research; i Contratos Ramón y CajalCD11c is an α integrin classically employed to define myeloid dendritic cells. Although there is little information about CD11c expression on human T cells, mouse models have shown an association of CD11c expression with functionally relevant T cell subsets. In the context of genital tract infection, we have previously observed increased expression of CD11c in circulating T cells from mice and women. Microarray analyses of activated effector T cells expressing CD11c derived from naïve mice demonstrated enrichment for natural killer (NK) associated genes. Here we find that murine CD11c+ T cells analyzed by flow cytometry display markers associated with non-conventional T cell subsets, including γδ T cells and invariant natural killer T (iNKT) cells. However, in women, only γδ T cells and CD8+ T cells were enriched within the CD11c fraction of blood and cervical tissue. These CD11c+ cells were highly activated and had greater interferon (IFN)-γ secretory capacity than CD11c- T cells. Furthermore, circulating CD11c+ T cells were associated with the expression of multiple adhesion molecules in women, suggesting that these cells have high tissue homing potential. These data suggest that CD11c expression distinguishes a population of circulating T cells during bacterial infection with innate capacity and mucosal homing potential

Unconventional phenotypes included in the CD11c⁺ T cell fraction after vaginal Chlamydia infection in mice.

<p>The frequency of the different subsets obtained from combining CD1d-tetramer, CD8α, γδTCR and NK1.1 expression is displayed for each group as a pie chart and as a complementary bar graph. Gating strategy was performed as described in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0154253#pone.0154253.g001" target="_blank">Fig 1</a></b> and in Materials and Methods. The frequency of CD11c positive cells in the T cell fraction as the mean ± SD is shown as a white number in the center of the pie chart for each group in blood (top) and genital tract (GT, bottom). Each colored portion of a pie chart indicates the percentage of a specific subset detailed in the bar chart below. The arcs around the pie show the molecule or combination of molecules to which those proportions correspond (see color legend indicating CD1d-tetramer, CD8α, γδTCR and NK1.1). *Indicates p<0.05 by Student’s t test analyses only for values >5% of the total CD11c⁺ T cells in vaginally (VAG)-infected mice seven days after infection (n = 4) compared to control (n = 3) animals.</p

Comparison of specific phenotype frequencies based on CD11c expression in blood samples from healthy women.

<p>Comparison of the frequency of CD8, γδTCR, MAIT and iNKT (Vα24) in CD11c⁺ and CD11c^-, CCR7^- CD3⁺ T cells from the same individual. (<b>a</b>) Fresh blood (n = 10) and (<b>b</b>) PBMC (n = 6). Gating strategy consisted on the following consecutive gates: lymphocytes, singlets, live CD14^- CD19^- CD3⁺ T cells and CCR7^- CD11c⁺or CD11c^- T cells (<i>see</i> <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0154253#pone.0154253.s003" target="_blank">S3 Fig</a></b> <i>for further details</i>). Data were analyzed using the paired Student’s t-test.</p