Far-Sidelobe Antenna Pattern Measurement of LiteBIRD Low Frequency Telescope in 1/4 Scale

International audiencePolarization of the cosmic microwave background (CMB) has crucial information on the inflationary universe. To detect these signals, it is necessary to suppress far sidelobes of a telescope, which contaminate the CMB signals with strong foreground radiation, such as the Galactic plane. LiteBIRD is the only funded CMB observation satellite for the 2020s, and the low frequency telescope (LFT; 34–161 GHz) is one of its telescopes. We measured near-field antenna patterns of the LFT using its 1/4-scaled model and examined far sidelobes up to 60° from the peaks. To cover the 20° field of view of the LFT, we investigated the antenna patterns at the edges of the focal plane as well as at the center. The measurement frequencies were 140–220 GHz, which correspond to the lowest bands (35–55 GHz) of the full-scale LFT. The measurements were consistent with the simulated far-sidelobe patterns at least −50 dB level, and showed that far sidelobes for two orthogonal polarization directions are consistent with each other down to −40 dB level. We also measured the cross-polarization patterns, and their peak level was less than −20 d

Disseminated Nocardia farcinica infection in a patient with myasthenia gravis successfully treated by linezolid: a case report and literature review.

Nocardiosis is increasingly being diagnosed because of a growing population of immunocompromised hosts and improvements in the detection of Nocardia species in clinical laboratories. Historically, sulphonamides have been the first-line therapy for the treatment of nocardiosis, but sulphonamides tend to have a high rate of drug allergy in clinical settings. In this report, we described a disseminated Nocardia farcinica infection that occurred in a patient with myasthenia gravis who suffered from multiple drug allergies and was successfully treated using linezolid. We undertook a review of the literature of previously reported cases of nocardiosis treated with linezolid. To date, only 15 cases of nocardiosis treated with linezolid have been published. All cases exhibited long-term tolerance of linezolid, and 14 of 15 cases showed either an improvement in or complete clearance of the infection. According to the literature review, linezolid is an attractive alternative to trimethoprim-sulfamethoxazole for the treatment of disseminated nocardiosis, despite limited clinical evidence to support this claim

Design and Synthesis of Cyclopropane Congeners of Resolvin E2, an Endogenous Proresolving Lipid Mediator, as Its Stable Equivalents

Lipid chemical mediator resolvins with highly potent anti-inflammatory activity can be leads to develop novel anti-inflammatory drugs; however, they are unstable in oxygen due to their characteristic polyunsaturated structures. To solve the problem, CP-RvE2 has been designed and synthesized in which the <i>cis</i>-olefin of RvE2 was replaced with a cyclopropane. CP-RvE2s were much more stable than RvE2 against autoxidation and equipotent or more potent than RvE2. CP-RvE2s were successfully identified as stable equivalents of RvE2

Concept design of the LiteBIRD satellite for CMB B-mode polarization

LiteBIRD is a candidate for JAXA's strategic large mission to observe the cosmic microwave background (CMB) polarization over the full sky at large angular scales. It is planned to be launched in the 2020s with an H3 launch vehicle for three years of observations at a Sun-Earth Lagrangian point (L2). The concept design has been studied by researchers from Japan, U.S., Canada and Europe during the ISAS Phase-A1. Large scale measurements of the CMB B-mode polarization are known as the best probe to detect primordial gravitational waves. The goal of LiteBIRD is to measure the tensor-to-scalar ratio (r) with precision of r < 0:001. A 3-year full sky survey will be carried out with a low frequency (34 - 161 GHz) telescope (LFT) and a high frequency (89 - 448 GHz) telescope (HFT), which achieve a sensitivity of 2.5 \u3bcK-arcmin with an angular resolution 30 arcminutes around 100 GHz. The concept design of LiteBIRD system, payload module (PLM), cryo-structure, LFT and verification plan is described in this paper