301 research outputs found
Brassica genomics: a complement to, and early beneficiary of, the Arabidopsis sequence.
Those studying the genus Brassica will be among the early beneficiaries of the now-completed Arabidopsis sequence. The remarkable morphological diversity of Brassica species and their relatives offers valuable opportunities to advance our knowledge of plant growth and development, and our understanding of rapid phenotypic evolution
The decay pi0 to gamma gamma to next to leading order in Chiral Perturbation Theory
The two photon decay width of the neutral pion is analyzed within the
combined framework of Chiral Perturbation Theory and the 1/Nc expansion up to
order p^6 and p^4 times 1/Nc in the decay amplitude. The eta' is explicitly
included in the analysis. It is found that the decay width is enhanced by about
4.5% due to the isospin-breaking induced mixing of the pure U(3) states. This
effect, which is of leading order in the low energy expansion, is shown to
persist nearly unchanged at next to leading order. The chief prediction for the
width with its estimated uncertainty is 8.10+-0.08 eV. This prediction at the
1% level makes the upcomming precision measurement of the decay width even more
urgent.
Observations on the eta and eta' can also be made, especially about their
mixing, which is shown to be significantly affected by next to leading order
corrections.Comment: 21 pages, two figure
Thermoelectric power of MgBBe
We investigated thermoelectric power of MgBBe (,
0.2, 0.3, 0.4, and 0.6). decreases systematically with , suggesting
that the hole density increases. Our band calculation shows that the increase
occurs in the -band. With the hole-doping, decreases.
Implication of this phenomenon is discussed within the BCS framework. While the
Mott formula explains only the linear part of at low temperature,
incorporation of electron-phonon interaction enables us to explain over
wide temperature range including the anomalous behavior at high temperature.Comment: 4 pages, 4 figure
Study of temperature dependent atomic correlations in MgB
We have studied the evolution with temperature of the local as well as the
average crystal structure of MgB using the real-space atomic pair
distribution function (PDF) measured by high resolution neutron powder
diffraction. We have investigated the correlations of the B-B and B-Mg nearest
neighbor pair motion by comparing, in the wide temperature range from T=10 K up
to T=600 K, the mean-square displacements (MSD) of single atoms with the
mean-square relative displacements (MSRD) obtained from the PDF peak
linewidths. The results show that the single atom B and Mg vibrations are
mostly decoupled from each other, with a small predominance of positive (in
phase) correlation factor for both the B-B and B-Mg pairs. The small positive
correlation is almost temperature independent, in contrast with our theoretical
calculations; this can be a direct consequence of the strong decay processes of
the anharmonic phonons
The depression in visual impairment trial (DEPVIT): trial design and protocol
<b>Background</b>
The prevalence of depression in people with a visual disability is high but screening for depression and referral for treatment is not yet an integral part of visual rehabilitation service provision. One reason for this may be that there is no good evidence about the effectiveness of treatments in this patient group. This study is the first to evaluate the effect of depression treatments on people with a visual impairment and co morbid depression.<p></p>
<b>Methods/design</b>
The study is an exploratory, multicentre, individually randomised waiting list controlled trial. Participants will be randomised to receive Problem Solving Therapy (PST), a ‘referral to the GP’ requesting treatment according to the NICE’s ‘stepped care’ recommendations or the waiting list arm of the trial. The primary outcome measure is change (from randomisation) in depressive symptoms as measured by the Beck’s Depression Inventory (BDI-II) at 6 months. Secondary outcomes include change in depressive symptoms at 3 months, change in visual function as measured with the near vision subscale of the VFQ-48 and 7 item NEI-VFQ at 3 and 6 months, change in generic health related quality of life (EQ5D), the costs associated with PST, estimates of incremental cost effectiveness, and recruitment rate estimation.<p></p>
<b>Discussion</b>
Depression is prevalent in people with disabling visual impairment. This exploratory study will establish depression screening and referral for treatment in visual rehabilitation clinics in the UK. It will be the first to explore the efficacy of PST and the effectiveness of NICE’s ‘stepped care’ approach to the treatment of depression in people with a visual impairment.<p></p>
Analytic Solution for the Critical State in Superconducting Elliptic Films
A thin superconductor platelet with elliptic shape in a perpendicular
magnetic field is considered. Using a method originally applied to circular
disks, we obtain an approximate analytic solution for the two-dimensional
critical state of this ellipse. In the limits of the circular disk and the long
strip this solution is exact, i.e. the current density is constant in the
region penetrated by flux. For ellipses with arbitrary axis ratio the obtained
current density is constant to typically 0.001, and the magnetic moment
deviates by less than 0.001 from the exact value. This analytic solution is
thus very accurate. In increasing applied magnetic field, the penetrating flux
fronts are approximately concentric ellipses whose axis ratio b/a < 1 decreases
and shrinks to zero when the flux front reaches the center, the long axis
staying finite in the fully penetrated state. Analytic expressions for these
axes, the sheet current, the magnetic moment, and the perpendicular magnetic
field are presented and discussed. This solution applies also to
superconductors with anisotropic critical current if the anisotropy has a
particular, rather realistic form.Comment: Revtex file and 13 postscript figures, gives 10 pages of text with
figures built i
A systematic review and meta-synthesis of the impact of low back pain on people's lives
Copyright @ 2014 Froud et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly credited.Background - Low back pain (LBP) is a common and costly problem that many interpret within a biopsychosocial model. There is renewed concern that core-sets of outcome measures do not capture what is important. To inform debate about the coverage of back pain outcome measure core-sets, and to suggest areas worthy of exploration within healthcare consultations, we have synthesised the qualitative literature on the impact of low back pain on people’s lives.
Methods - Two reviewers searched CINAHL, Embase, PsycINFO, PEDro, and Medline, identifying qualitative studies of people’s experiences of non-specific LBP. Abstracted data were thematic coded and synthesised using a meta-ethnographic, and a meta-narrative approach.
Results - We included 49 papers describing 42 studies. Patients are concerned with engagement in meaningful activities; but they also want to be believed and have their experiences and identity, as someone ‘doing battle’ with pain, validated. Patients seek diagnosis, treatment, and cure, but also reassurance of the absence of pathology. Some struggle to meet social expectations and obligations. When these are achieved, the credibility of their pain/disability claims can be jeopardised. Others withdraw, fearful of disapproval, or unable or unwilling to accommodate social demands. Patients generally seek to regain their pre-pain levels of health, and physical and emotional stability. After time, this can be perceived to become unrealistic and some adjust their expectations accordingly.
Conclusions - The social component of the biopsychosocial model is not well represented in current core-sets of outcome measures. Clinicians should appreciate that the broader impact of low back pain includes social factors; this may be crucial to improving patients’ experiences of health care. Researchers should consider social factors to help develop a portfolio of more relevant outcome measures.Arthritis Research U
Apparent diffusion coefficient restriction in the white matter: going beyond acute brain territorial ischemia
BACKGROUND: Reduction of apparent diffusion coefficient (ADC) values in white matter is not always ischaemic in nature.
METHODS: We retrospectively analysed our MRI records featuring reduced ADC values in the centrum semiovale without grey matter involvement or significant vasogenic oedema.
RESULTS: Several conditions showed the aforementioned MR findings: moose-horn lesions on coronal images in X-linked Charcot-Marie-Tooth disease; small fronto-parietal lesions in Menkes disease; marked signal abnormalities in the myelinised regions in the acute neonatal form of maple syrup urine disease; strip-like involvement of the corpus callosum in glutaric aciduria type 1; persistent periventricular parieto-occipital abnormalities in phenylketonuria; diffuse signal abnormalities with necrotic evolution in global cerebral anoxia or after heroin vapour inhalation; almost completely reversible symmetric fronto-parietal lesions in methotrexate neurotoxicity; chain-like lesions in watershed ischaemia; splenium involvement that normalises in reversible splenial lesions or leads to gliosis in diffuse axonal injury.
CONCLUSION: Neuroradiologists must be familiar with these features, thereby preventing misdiagnosis and inappropriate management
Indication for the disappearance of reactor electron antineutrinos in the Double Chooz experiment
The Double Chooz Experiment presents an indication of reactor electron
antineutrino disappearance consistent with neutrino oscillations. A ratio of
0.944 0.016 (stat) 0.040 (syst) observed to predicted events was
obtained in 101 days of running at the Chooz Nuclear Power Plant in France,
with two 4.25 GW reactors. The results were obtained from a single 10
m fiducial volume detector located 1050 m from the two reactor cores. The
reactor antineutrino flux prediction used the Bugey4 measurement as an anchor
point. The deficit can be interpreted as an indication of a non-zero value of
the still unmeasured neutrino mixing parameter \sang. Analyzing both the rate
of the prompt positrons and their energy spectrum we find \sang = 0.086
0.041 (stat) 0.030 (syst), or, at 90% CL, 0.015 \sang 0.16.Comment: 7 pages, 4 figures, (new version after PRL referee's comments
Surgical management of dural arteriovenous fistulas with transosseous arterial feeders involving the jugular bulb
Dural arteriovenous fistulas located in the vicinity of the jugular foramen are complex vascular malformations and belong to the most challenging skull base lesions to treat. The authors comprehensively analyze multiple features in a series of dural arteriovenous fistulas with transosseous arterial feeders involving the jugular bulb. Four patients who underwent surgery via the transcondylar approach to treat dural arteriovenous fistulas around the jugular foramen were retrospectively reviewed. Previously, endovascular treatment was attempted in all patients. The success of the surgical treatment was examined with postoperative angiography. Complete obliteration of the dural arteriovenous fistulas (DAVFs) was achieved in three patients, and significant flow reduction in one individual. All patients had a good postoperative outcome, and only one experienced mild hypoglossal nerve palsy. Despite extensive bone drilling, an occipitocervical fusion was necessary in only one patient with bilateral lesions. The use of an individually tailored transcondylar approach to treat dural arteriovenous fistulas at the region of the jugular foramen is most effective. This approach allows for complete obliteration of the connecting arterial feeders, and removal of bony structures containing pathological vessels
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