417 research outputs found
Performance, carcass characteristics and ingestive behavior of feedlot lambs fed fresh or ensiled sugar cane
Trinta cordeiros da raça Santa Inês, 26,2±0,6kg e 151±1,7 dias de idade, foram confinados para avaliar os efeitos da utilização de silagens de cana-de-açúcar sobre o desempenho, as características da carcaça e o comportamento ingestivo. As rações experimentais foram compostas de 50% de volumoso e 50% de concentrado, diferindo quanto ao tipo do volumoso utilizado: cana-de-açúcar in natura, silagem de cana-de-açúcar sem aditivo e silagem de cana-de-açúcar aditivada com Lactobacillus buchneri (5x10(4) UFC/g de MV). Não houve diferença (P>0,05) para o consumo de MS, ganho de peso vivo, conversão alimentar e parâmetros de carcaça entre os tratamentos. O tempo de ingestão (min/g FDN) e a eficiência de ruminação (g MS/h) foram menores (P<0,05) para os tratamentos contendo silagem de cana-de-açúcar. Silagens de cana-de-açúcar não alteraram o desempenho e as características da carcaça dos cordeiros em relação à cana de açúcar in natura. A utilização do aditivo microbiano contendo o L. buchneri na ensilagem da cana-de-açúcar não alterou as variáveis avaliadas.Thirty Santa Ines ram lambs, 26.2±0.6kg and 151±1.7 day-old, were penned to evaluate the effects of feeding sugar cane silages on performance, carcass characteristics and ingestive behavior. Lambs were fed a 50:50 (concentrate:roughage ratio) TMR. Experimental treatments were: fresh sugar cane, sugar cane silage without additive and sugar cane silage treated with Lactobacillus buchneri (5x10(4) cfu/g wet basis). No differences (P>0.05) on dry matter intake, average daily gain, feed conversion and carcass characteristics were observed among treatments. Eating time (min/g NDF) and rumination efficiency (g DM/h) were lower (P<0.05) for silage diets. Sugar cane silage had no detrimental effect on lamb performance and carcass characteristics compared to fresh sugar cane. Adding L. buchneri to sugar cane silage did not change the evaluated characteristics
Nitrogen source on performance of feedlot young bulls fed hydrolyzed sugarcane bagasse diets
Oitenta e um machos não castrados das raças Nelore (27), Canchim (27) e Holandesa (27), com peso médio inicial de 360kg e idade média de 18 meses, foram utilizados para avaliar os efeitos da substituição de fonte de proteína verdadeira (farelo de soja), por nitrogênio não protéico (NNP), uréia ou amiréia (fonte de nitrogênio não protéico de suposta liberação gradativa) sobre o desempenho de bovinos confinados. O delineamento experimental foi o de blocos inteiramente ao acaso com três animais por baia e nove baias por tratamento. Os blocos foram delineados de acordo com o peso inicial e na raça. As rações experimentais continham BTPV (45% MS da dieta) e BIN (5% MS da dieta) como fontes de volumosos e 50% de concentrado. Os tratamentos consistiam de: 1) concentrado contendo farelo de soja (FS); 2) concentrado contendo uréia e 3) concentrado contendo amiréia (A-150S). O consumo de matéria seca (CMS) foi de 8,99; 7,43 e 7,69kg/dia, o ganho de peso diário (GPD) foi de 0,983; 0,368 e 0,404kg/dia e a conversão alimentar (CA) 9,56; 20,14 e 19,54kg MS/kg de ganho para os tratamentos FS, uréia e A-150S, respectivamente. As rações com FS apresentaram proporcionalmente maior (P<0,01) CMS e maior GPD e melhor CA em relação aos tratamentos uréia e A-150S. As rações com uréia e A-150S não diferiram (P>0,05) entre si. A substituição do FS por fontes de NNP reduziu o desempenho de bovino de corte em terminação.Eighty-one young bulls (27 Nellore, 27 Canchim, and 27 Holstein), averaging 18-month-old and weighting 360kg of initial body weight (BW), were used to evaluate the effects of nitrogen sources on feedlot performance. Treatments were assigned in a completely randomized block design using three steers per stall and nine per treatment. Blocks were defined by initial BW and breed. Experimental treatments were: 1) soybean meal, 2) urea, and 3) starea. Diets were isonitrogenous and isoenergetic composed by 50% concentrate and 50% forage (45% hydrolyzed sugarcane bagasse + 5% in natura sugarcane bagasse). Dry matter intakes (DMI) were 8.99, 7.43, and 7.69kg/day, average daily gains (ADG) were 0.983, 0.368, and 0.404kg/day and feed efficiencies were 9.56, 20.14, and 19.54kg DM/kg of gain for soybean meal, urea and starea treatments, respectively for steers fed. Diets with soybean meal showed proportionally higher (P<0.01) DMI, higher average daily gain and better feed efficiency compared to urea and starea diets. No differences (P>0.05) between urea and starea treatments were observed. Replacement of soybean meal by nonprotein nitrogen sources decreased the finishing beef steers performance
Effect of raw sugar cane bagasse on performance and ingestive behavior of beef cattle
Avaliou-se o efeito da utilização do bagaço de cana-de-açúcar in natura (BIN), obtido por dois métodos de extração do açúcar, moagem convencional ou difusão, como fonte de fibra em dietas que continham bagaço tratado sob pressão e vapor (BTPV), como principal fonte de volumoso sobre o desempenho e o comportamento ingestivo de bovinos confinados. Para avaliação do desempenho, foram utilizados 84 machos não castrados das raças Nelore, Canchim e Holandesa, com média de peso inicial de 270kg, distribuídos em delineamento de blocos ao acaso. Para a avaliação do comportamento ingestivo, foram utilizados quatro garrotes da raça Nelore, em delineamento de quadrado latino 4 x 4. Os tratamentos consistiram na substituição do BTPV pelo BIN na matéria seca, constituindo as dietas experimentais: 5% BIN moagem convencional; 5% BIN difusão, 10% BIN difusão e 15% BIN difusão. O consumo de MS foi menor no tratamento com 15% de BIN obtido por difusão (BINdif), em relação ao teor de inclusão de 10%. Não houve diferença (P>0,05) entre os tratamentos para ganho diário de peso, conversão alimentar e peso vivo final entre os tratamentos. Os tempos despendidos com as atividades de ruminação (minutos/kg de MS) e mastigação (minutos/kg de MS ou de FDN) foram maiores (P<0,05) no tratamento com 15% de BINdif na dieta. O BINdif pode ser utilizado como fonte de fibra íntegra em até 15% da MS da dieta sem prejudicar o desempenho dos animais.This study was conducted to evaluate effects of replacing steam pressure treated sugar cane bagasse by two types of raw sugar cane bagasse extracted through grinding or diffusion, on performance and ingestive behavior of beef cattle. Eighty four young bulls (Nelore, Canchim and Holstein) with 270kg of body weight at the beginning of the experiment were used in a randomized block design. Ingestive behavior was evaluated using four Nelore young bulls in a 4 x 4 Latin square design. Treatments were the direct substitution of steam pressure treated sugarcane bagasse by raw bagasse (RB), corresponding to the experimental treatments: 5% RB from grinding; 5% RB from diffusion; 10% RB from diffusion and 15% RB from diffusion. Dry matter intake was lower in treatment with 15% of bagasse obtained by diffusion (BINdif) in comparison to 10% BINdif. There were no differences (P>0.05) among treatments for average daily gain, feed conversion and final live weight. Ruminating time (minutes/kg of DM) and chewing time (minutes/kg of DM or NDF) was greater (P>0.05) when BINdif was added at 15% level to diets. BINdif can be added up to 15% of the dietary DM with no detrimental effect on beef cattle performance
Effects of starch sources and processing on nutrient digestibility and ruminal parameters of lactating cows
Cinco vacas holandesas pluríparas, com cânulas no rúmen e no duodeno, foram distribuídas em delineamento de quadrado latino 5 x 5. As vacas foram submetidas a cinco rações experimentais contendo 40% de cana-de-açúcar, 60% de concentrado e cerca de 30% de amido. As rações diferiram quanto ao processamento ou à fonte principal do amido utilizado: milho grosseiramente moído, milho finamente moído, milho floculado a 310g/l, milho floculado a 360g/l ou raspa de mandioca. Não houve diferença (P>0,05) no consumo de matéria seca entre os tratamentos. A digestibilidade ruminal do amido foi maior na ração que continha raspa de mandioca. As digestibilidades ruminal da fibra em detergente neutro e da fibra em detergente ácido não diferiram entre os tratamentos. Os dados médios de pH ruminal se mantiveram acima de 6,0, exceto às 2 e às 4h após a alimentação com a dieta que continha raspa de mandioca. Não houve efeito significativo dos tratamentos sobre a concentração de ácidos graxos voláteis totais. O processo de floculação promoveu aumento da digestibilidade do amido do milho, em relação à moagem de forma grosseira. A digestibilidade ruminal do amido presente na raspa de mandioca foi maior do que a do milho, independentemente da forma de processamento utilizada.Five multiparous lactating Holsteins cows, cannulated in the rumen and proximal duodenum, were used in a 5 x 5 latin square. Cows were fed a 40:60 forage: concentrate diet (40% fresh sugar cane and 60% concentrate). Diets were formulated to have 30% of starch and treatments were starch sources and ration processing forms: cracked corn, finely ground corn, flaked corn at 310g/l, flaked corn at 360g/l, or cassava scrapings. No difference (P>0.05) was observed among treatments for dry matter intake. Starch ruminal digestibility was higher for cassava scrapings treatment. NDF and ADF digestibility were similar among treatments. Average values of ruminal pH were above 6, except at 2 and 4h after feeding the cassava diet. There was no effect of treatment on concentrations of total volatile fatty acids. The flocculation process increased corn starch digestibility. Ruminal degradability of the cassava scrapings starch was higher than corn, without effect of processing form
NoX: a Compact Open-Source RISC-V Processor for Multi-Processor Systems-on-Chip
IoT applications are one of the driving forces in making systems energy and
power-efficient, given their resource constraints. However, because of
security, latency, and transmission, we advocate for local computing through
multi-processor systems-on-chip (MPSoCs) for edge computing. The RISC-V ISA has
grown in academia and industry due to its flexibility. Still, available
open-source cores cannot be seamlessly integrated into MPSoCs for a fast time
to market. This paper presents NoX, a compact open-source plug-and-play 32-bit
RISC-V core designed in System Verilog for efficient data processing in MPSoCs.
NoX has a 4-stage single-issue in-order pipeline with full bypass, providing an
efficient resource-constrained architecture. Compared to industry and academia
resource-constrained RISC-V cores, NoX offers a better resource usage and
performance trade-off
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise is generally referred to as ‘accidental cell death’ (ACD). In most settings, however, cell death is initiated by a genetically encoded apparatus, correlating with the fact that its course can be altered by pharmacologic or genetic interventions. ‘Regulated cell death’ (RCD) can occur as part of physiologic programs or can be activated once adaptive responses to perturbations of the extracellular or intracellular microenvironment fail. The biochemical phenomena that accompany RCD may be harnessed to classify it into a few subtypes, which often (but not always) exhibit stereotyped morphologic features. Nonetheless, efficiently inhibiting the processes that are commonly thought to cause RCD, such as the activation of executioner caspases in the course of apoptosis, does not exert true cytoprotective effects in the mammalian system, but simply alters the kinetics of cellular demise as it shifts its morphologic and biochemical correlates. Conversely, bona fide cytoprotection can be achieved by inhibiting the transduction of lethal signals in the early phases of the process, when adaptive responses are still operational. Thus, the mechanisms that truly execute RCD may be less understood, less inhibitable and perhaps more homogeneous than previously thought. Here, the Nomenclature Committee on Cell Death formulates a set of recommendations to help scientists and researchers to discriminate between essential and accessory aspects of cell death
Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential
Bax, a pro-apoptotic member of the Bcl-2 family, is a cytosolic protein that inserts into mitochondrial membranes upon induction of cell death. Using the green fluorescent protein fused to Bax (GFP-Bax) to quantitate mitochondrial binding in living cells we have investigated the cause of Bax association with mitochondria and the time course relative to endogenous and induced changes in mitochondrial membrane potential (Delta Psi (m)). We have found that staurosporine (STS) induces a loss in Delta Psi (m) before GFP-Bax translocation can be measured. the onset of the Delta Psi (m) loss is followed by a rapid and complete collapse of Delta Psi (m) which is followed by Bax association with mitochondria. the mitochondria uncoupler FCCP, in the presence of the F-1-F-0 ATPase inhibitor oligomycin, can trigger Bax translocation to mitochondria suggesting that when ATP levels are maintained a collapse of Delta Psi (m) induces Bax translocation. Neither FCCP nor oligomycin alone alters Bax location. Bax association with mitochondria is also triggered by inhibitors of the electron transport chain, antimycin and rotenone, compounds that collapse Delta Psi (m) without inducing rapid ATP hydrolysis that typically occurs with uncouplers such as FCCP. Taken together, our results suggest that alterations in mitochondrial energization associated with apoptosis can initiate Bax docking to mitochondria.NINDS, Biochem Sect, Surg Neurol Branch, NIH, Bethesda, MD 20892 USAUniversidade Federal de São Paulo, Dept Farmacol, São Paulo, BrazilNICHHD, Lab Cellular & Mol Neurophysiol, NIH, Bethesda, MD 20892 USAMed Univ S Carolina, Charleston, SC 29425 USAUniversidade Federal de São Paulo, Dept Farmacol, São Paulo, BrazilWeb of Scienc
THEORETICAL BASE TO ORGANIZATIONS OF THE CONCLUSION OF THE CONCLUSIONS IN NONMONOTONIC AMBIENCE ON BASE CONDITIONALLYHUNG VARIABLE
It is offered one of the approach to organizations of the notional thinking of the intellectual systems, connected with development theoretical base conclusion of the conclusions in free non monotonic problem-solving area on base conditionally hung variable
OPTIMIZATION OF SOLID-LIQUID EXTRACTION OF ETHANOL OBTAINED BY SOLID-STATE FERMENTATION OF SURGARCANE BAGASSE
ABSTRACT -Solid-state fermentation has arrived as an alternative to reduce the amount of waste water in ethanol fermentation. However, the recovery of ethanol from solid medium should be investigated, since depending of experimental condition used in the extraction, significant difference in the results can be obtained. In this work was investigated the influence of temperature (30-50°C), solid to liquid ratio (0.1-0.4 wt%) and orbital agitation (50-180 rpm) in the recovery of ethanol from sugarcane bagasse at different fermentation conditions of moisture content (50-80%) and ethanol amount (5-20 wt%). The highest recovering efficiency was 99,8% at 30°C, initial ethanol amount of 10 wt%, orbital agitation of 100 rpm and moisture content of 60%. The main contribution of this work was to demonstrate that the amount of water used in the extraction is lesser than that used in traditional liquid fermentation, making possible to obtain a more concentrated broth, saving with water treatment and energy
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