9,150 research outputs found
Magnetoresistance, Micromagnetism and Domain Wall Effects in Epitaxial Fe and Co Structures with Stripe Domains
We review our recent magnetotransport and micromagnetic studies of
lithographically defined epitaxial thin film structures of bcc Fe and hcp Co
with stripe domains. Micromagnetic structure and resistivity anisotropy are
shown to be the predominant sources of low field magnetoresistance (MR) in
these microstructures, with domain wall (DW) effects smaller but observable
(DW-MR ). In Fe, at low temperature, in a regime in which fields
have a significant effect on electron trajectories, a novel negative DW
contribution to the resistivity is observed. In hcp Co microstructures,
temperature dependent transport measurements for current perpendicular and
parallel to walls show that any additional resistivity due to DW scattering is
very small.Comment: 7 pages, 8 figures, to appear in Journal of Applied Physics 199
Author Impact Measures in Communication Sciences and Disorders
Author impact metrics were collected from approximately 2000 academic research faculty in 257 accredited universities in the US and Canada. Three databases (Scopus, Google Scholar, and ResearchGate) were utilized. Indices (e.g., publications, citations, and h-index) were examined as a function of gender, rank, area of study, region, and Carnegie Classification
ESEM-EDS investigation of the weathering of a heritage sydney sandstone
The degradation of Sydney sandstone used to build the heritage St Mary's Cathedral in Sydney, Australia, has been investigated using environmental scanning electron microscopy combined with energy dispersive X-ray spectroscopy. This technique provided the structural details of the cementing clay and an elemental characterization the sandstone. The observed differences in the elemental composition of the unweathered and weathered sandstones were associated with changes to the clay microstructure upon weathering. The results support the substitution theory that Fe3+ replaces Al3+ in the kaolinite clay component upon weathering. An examination of the impurities present prior to a nonstructural iron removal treatment revealed the presence of minerals that may provide a source of the elements responsible for the substitution process. © 2011 Microscopy Society Of America
The Application of Microperforated Panels in Duct Systems
Microperforated panels (MPPs) are usually considered to be an alternative sound absorbing surface treatment in architectural acoustics applications, where they can serve as effective, fiber-free replacements for the more traditional glass fibers and other porous materials. However, the areas in which MPPs may be applied are not only limited to the replacement of conventional sound absorbing materials, but MPPs can also be used in spaces where more conventional materials cannot be conveniently used. For example, heating, ventilation, and air conditioning (HVAC) duct application is one area where MPPs can be used as a stand-alone material,in contrast with glass fiber, which typically must be covered by perforated surface treatments to prevent erosion of the fibers due to the flow. In this study, it will be shown how a suitably designed MPP can be an effective noise control element in ducts by reducing fan and flow noise while at the same time maintaining the flow delivery performance of the duct
Deforestation dynamics in an endemic-rich mountain system: Conservation successes and challenges in West Java 1990–2015
While much has been published on recent rates of forest loss in the Sundaic lowlands, deforestation rates and patterns on Java’s endemic-rich mountains have been rather neglected. We used nearly 1000 Landsat images to examine spatio-altitudinal and temporal patterns of forest loss in montane West Java over the last 28 years, and the effectiveness of protected areas in halting deforestation over that period. Around 40% of forest has been lost since 1988, the bulk occurring pre-2000 (2.5% per annum), falling to 1% per annum post-2007. Most deforestation has occurred at lower altitudes (<1000 m above sea level), both as attrition of the edges of forested mountain blocks as well as the near-total clearance of lower-altitude forested areas. Deforestation within protected areas was rife pre-2000, but greatly decreased thereafter, almost ceasing post-2007 in protected areas of high International Union for Conservation of Nature (IUCN) status. While this trend is welcome, it must be stressed that the area of remaining forest is only 5234 km2, that most accessible lower-altitude forest has already disappeared, and that the extant montane forest is largely fragmented and isolated. The biological value of these forests is huge and without strong intervention we anticipate imminent loss of populations of taxa such as the Javan Slow Loris Nycticebus javanicus and Javan Green Magpie Cissa thalassina
Impactor flux and cratering on Ceres and Vesta: Implications for the early Solar System
We study the impactor flux and cratering on Ceres and Vesta caused by the
collisional and dynamical evolution of the asteroid Main Belt. We develop a
statistical code based on a well-tested model for the simultaneous evolution of
the Main Belt and NEA size distributions. This code includes catastrophic
collisions and noncollisional removal processes such as the Yarkovsky effect
and the orbital resonances. The model assumes that the dynamical depletion of
the early Main Belt was very strong, and owing to that, most Main Belt
comminution occurred when its dynamical structure was similar to the present
one. Our results indicate that the number of D > 1 km Main Belt asteroids
striking Ceres and Vesta over the Solar System history are approximately 4 600
and 1 100 respectively. The largest Main Belt asteroids expected to have
impacted Ceres and Vesta had diameters of 71.7 km and 21.1 km. The number of D
> 0.1 km craters on Ceres is \sim 3.4 \times 10^8 and 6.2 \times 10^7 on Vesta.
The number of craters with D > 100 km are 47 on Ceres and 8 on Vesta. Our study
indicates that the D = 460 km crater observed on Vesta had to be formed by the
impact of a D \sim 66.2 km projectile, which has a probability of occurr \sim
30% over the Solar System history. If significant discrepancies between our
results about the cratering on Ceres and Vesta and data obtained from the Dawn
Mission were found, they should be linked to a higher degree of collisional
evolution during the early Main Belt and/or the existence of the late heavy
bombardment. An increase in the collisional activity in the early phase may be
provided for an initial configuration of the giant planets consistent with, for
example, the Nice model. From this, the Dawn Mission would be able to give us
clues about the initial configuration of the early Solar System and its
subsequent dynamical evolution.Comment: Accepted for publication in Astronomy and Astrophysic
Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles
Background: There is renewed interest in the development of poxvirus vector-based HIV vaccines due to the protective effect observed with repeated recombinant canarypox priming with gp120 boosting in the recent Thai placebo-controlled trial. This study sought to investigate whether a heterologous prime-boost-boost vaccine regimen in Chinese cynomolgus macaques with a DNA vaccine and recombinant poxviral vectors expressing HIV virus-like particles bearing envelopes derived from the most prevalent clades circulating in sub-Saharan Africa, focused the antibody response to shared neutralising epitopes.
Methods: Three Chinese cynomolgus macaques were immunised via intramuscular injections using a regimen composed of a prime with two DNA vaccines expressing clade A Env/clade B Gag followed by boosting with recombinant fowlpox virus expressing HIV-1 clade D Gag, Env and cholera toxin B subunit followed by the final boost with recombinant modified vaccinia virus Ankara expressing HIV-1 clade C Env, Gag and human complement protein C3d. We measured the macaque serum antibody responses by ELISA, enumerated T cell responses by IFN-gamma ELISpot and assessed seroneutralisation of HIV-1 using the TZM-bl beta-galactosidase assay with primary isolates of HIV-1.
Results: This study shows that large and complex synthetic DNA sequences can be successfully cloned in a single step into two poxvirus vectors: MVA and FPV and the recombinant poxviruses could be grown to high titres. The vaccine candidates showed appropriate expression of recombinant proteins with the formation of authentic HIV virus-like particles seen on transmission electron microscopy. In addition the b12 epitope was shown to be held in common by the vaccine candidates using confocal immunofluorescent microscopy. The vaccine candidates were safely administered to Chinese cynomolgus macaques which elicited modest T cell responses at the end of the study but only one out of the three macaques elicited an HIV-specific antibody response. However, the antibodies did not neutralise primary isolates of HIV-1 or the V3-sensitive isolate SF162 using the TZM-bl b-galactosidase assay.
Conclusions: MVA and FP9 are ideal replication-deficient viral vectors for HIV-1 vaccines due to their excellent safety profile for use in humans. This study shows this novel prime-boost-boost regimen was poorly immunogenic in Chinese cynomolgus macaques
Conceptual energy and water recovery system for self-sustained nano membrane toilet
With about 2.4 billion people worldwide without access to improved sanitation facilities, there is a strong incentive for development of novel sanitation systems to improve the quality of life and reduce mortality. The Nano Membrane Toilet is expected to provide a unique household-scale system that would produce electricity and recover water from human excrement and urine. This study was undertaken to evaluate the performance of the conceptual energy and water recovery system for the Nano Membrane Toilet designed for a household of ten people and to assess its self-sustainability. A process model of the entire system, including the thermochemical conversion island, a Stirling engine and a water recovery system was developed in Aspen Plus®. The energy and water recovery system for the Nano Membrane Toilet was characterised with the specific net power output of 23.1 Wh/kgsettledsolids and water recovery rate of 13.4 dm3/day in the nominal operating mode. Additionally, if no supernatant was processed, the specific net power output was increased to 69.2 Wh/kgsettledsolids. Such household-scale system would deliver the net power output (1.9–5.8 W). This was found to be enough to charge mobile phones or power clock radios, or provide light for the household using low-voltage LED bulbs
Simplified Aid for Extra-Vehicular Activity Rescue (SAFER) Battery Assessment
In 2013, the Boeing Company model 787-8 Dreamliner commercial aircraft experienced three catastrophic lithium (Li) battery failures. The cause of each failure resulted in a single-cell thermal runaway (TR) condition, which propagated to adjacent battery cells. Two of the failures involved rechargeable lithium-ion (Li-Ion) batteries, and the third event involved a nonrechargeable lithium-manganese dioxide (Li-MnO2) battery. In response to these Li battery failures, the NASA Engineering and Safety Center (NESC) approved a technical assessment of the International Space Station Simplified Aid for Extra-Vehicular Activity Rescue (SAFER) Li non-rechargeable battery. This assessment was conducted to evaluate the SAFER Li nonrechargeable battery safety design features against Boeing 787 Dreamliner Li battery failure lessons learned. Specifically, this investigation focused on assessing the severity of a SAFER battery TR hazard conditions
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