609 research outputs found

    The Life-and-Death Journey of the Soul : Interpreting the Myth of Er

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    A nevetĂ©s a görög kultĂșrĂĄban

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    Justifying the world as an aesthetic phenomenon

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    This article scrutinises one of the most challenging theses of Nietzsche's Birth of Tragedy, that only as an aesthetic phenomenon can existence and the world be (or appear to be) ‘justified’. Through a close examination of the work's frequently masked revaluation of a series of Greek sources of thinking, not least its ‘inversion’ of both the metaphysics and the aesthetics of Plato's Republic, the article shows how the thesis of aesthetic ‘justification’ is caught up in a tension between Apolline and Dionysian interpretations, the first entailing a quasi-Homeric sense that the Olympians justify human existence by living a transfigured form of it themselves, the second involving a tragic insight into reality as itself the creative work of a ‘world-artist’, the latter allusively associated by Nietzsche with the philosophy of Heraclitus.PostprintPeer reviewe

    Normalization of Collisional Decoherence: Squaring the Delta Function, and an Independent Cross-Check

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    We show that when the Hornberger--Sipe calculation of collisional decoherence is carried out with the squared delta function a delta of energy instead of a delta of the absolute value of momentum, following a method introduced by Di\'osi, the corrected formula for the decoherence rate is simply obtained. The results of Hornberger and Sipe and of Di\'osi are shown to be in agreement. As an independent cross-check, we calculate the mean squared coordinate diffusion of a hard sphere implied by the corrected decoherence master equation, and show that it agrees precisely with the same quantity as calculated by a classical Brownian motion analysis.Comment: Tex: 14 pages 7/30/06: revisions to introduction, and references added 9/29/06: further minor revisions and references adde

    Influence Functionals and the Accelerating Detector

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    The influence functional is derived for a massive scalar field in the ground state, coupled to a uniformly accelerating DeWitt monopole detector in D+1D+1 dimensional Minkowski space. This confirms the local nature of the Unruh effect, and provides an exact solution to the problem of the accelerating detector without invoking a non-standard quantization. A directional detector is presented which is efficiently decohered by the scalar field vacuum, and which illustrates an important difference between the quantum mechanics of inertial and non-inertial frames. From the results of these calculations, some comments are made regarding the possibility of establishing a quantum equivalence principle, so that the Hawking effect might be derived from the Unruh effect.Comment: 32 page

    Pair Creation of Black Holes During Inflation

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    Black holes came into existence together with the universe through the quantum process of pair creation in the inflationary era. We present the instantons responsible for this process and calculate the pair creation rate from the no boundary proposal for the wave function of the universe. We find that this proposal leads to physically sensible results, which fit in with other descriptions of pair creation, while the tunnelling proposal makes unphysical predictions. We then describe how the pair created black holes evolve during inflation. In the classical solution, they grow with the horizon scale during the slow roll-down of the inflaton field; this is shown to correspond to the flux of field energy across the horizon according to the First Law of black hole mechanics. When quantum effects are taken into account, however, it is found that most black holes evaporate before the end of inflation. Finally, we consider the pair creation of magnetically charged black holes, which cannot evaporate. In standard Einstein-Maxwell theory we find that their number in the presently observable universe is exponentially small. We speculate how this conclusion may change if dilatonic theories are applied.Comment: 29 pages, LaTeX, 3 figures, submitted to Phys. Rev. D; minor typos corrected, missing minus sign in Eq. (3.11) inserte

    Copper induces Cu-ATPase ATP7A mRNA in a fish cell line, SAF1

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    Copper transporting ATPase, ATP7A, is an ATP dependent copper pump present in all vertebrates, critical for the maintenance of intracellular and whole body copper homeostasis. Effects of copper treatment on ATP7A gene expression in fibroblast cells (SAF1) of the sea bream (Sparus aurata) were investigated by qRT-PCR and by a medium density microarray from a closely related species, striped sea bream (Lithognathus mormyrus). To discriminate between the effects of Cu and other metals, SAF1 cells were exposed to sub-toxic levels of Cu, Zn and Cd. Expression of Cu homeostasis genes copper transporter 1 (CTR1), Cu ATPase (ATP7A), Cu chaperone (ATOX1) and metallothionein (MT) together with the oxidative stress markers glutathione reductase (GR) and Cu/Zn superoxide dismutase (CuZn/SOD) were measured 0, 4 and 24 hours post-exposure by qRT-PCR. Microarray was conducted on samples from 4 hours post Cu exposure. Cu, Zn and Cd increased MT and GR mRNA levels, while only Cu increased ATP7A mRNA levels. Microarray results confirmed the effects of Cu on ATP7A and MT and in addition showed changes in the expression of genes involved in protein transport and secretion. Results suggest that ATP7A may be regulated at the transcriptional level directly by Cu and by a mechanism that is different from that exerteted by metals on MT genes
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