1,639 research outputs found
Integral group actions on symmetric spaces and discrete duality symmetries of supergravity theories
For a split, simply connected, semisimple Lie group of rank
and the maximal compact subgroup of , we give a method for computing
Iwasawa coordinates of using the Chevalley generators and the Steinberg
presentation. When is a scalar coset for a supergravity theory in
dimensions , we determine the action of the integral form
on . We give explicit results for the action of the
discrete --duality groups and on the
scalar cosets and
for type IIB supergravity
in ten dimensions and 11--dimensional supergravity in dimensions,
respectively. For the former, we use this to determine the discrete U--duality
transformations on the scalar sector in the Borel gauge and we describe the
discrete symmetries of the dyonic charge lattice. We determine the
spectrum--generating symmetry group for fundamental BPS solitons of type IIB
supergravity in dimensions at the classical level and we propose an
analog of this symmetry at the quantum level. We indicate how our methods can
be used to study the orbits of discrete U--duality groups in general
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Diffusion-Based smoothers for spatial filtering of gridded geophysical data
© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Grooms, I., Loose, N., Abernathey, R., Steinberg, J. M., Bachman, S. D., Marques, G., Guillaumin, A. P., & Yankovsky, E. Diffusion-Based smoothers for spatial filtering of gridded geophysical data. Journal of Advances in Modeling Earth Systems, 13(9), (2021): e2021MS002552, https://doi.org/10.1029/2021MS002552.We describe a new way to apply a spatial filter to gridded data from models or observations, focusing on low-pass filters. The new method is analogous to smoothing via diffusion, and its implementation requires only a discrete Laplacian operator appropriate to the data. The new method can approximate arbitrary filter shapes, including Gaussian filters, and can be extended to spatially varying and anisotropic filters. The new diffusion-based smoother's properties are illustrated with examples from ocean model data and ocean observational products. An open-source Python package implementing this algorithm, called gcm-filters, is currently under development.I.G. and N.L. are supported by NSF OCE 1912332. R.A. is supported by NSF OCE 1912325. J.S. is supported by NSF OCE 1912302. S.B. and G.M. are supported by NSF OCE 1912420. A.G. and E.Y. are supported by NSF GEO 1912357 and NOAA CVP NA19OAR4310364
At risk of being risky: The relationship between "brain age" under emotional states and risk preference.
Developmental differences regarding decision making are often reported in the absence of emotional stimuli and without context, failing to explain why some individuals are more likely to have a greater inclination toward risk. The current study (N=212; 10-25y) examined the influence of emotional context on underlying functional brain connectivity over development and its impact on risk preference. Using functional imaging data in a neutral brain-state we first identify the "brain age" of a given individual then validate it with an independent measure of cortical thickness. We then show, on average, that "brain age" across the group during the teen years has the propensity to look younger in emotional contexts. Further, we show this phenotype (i.e. a younger brain age in emotional contexts) relates to a group mean difference in risk perception - a pattern exemplified greatest in young-adults (ages 18-21). The results are suggestive of a specified functional brain phenotype that relates to being at "risk to be risky.
Search for corannulene (C20H10) in the Red Rectangle
Polycyclic Aromatic Hydrocarbons (PAHs) are widely accepted as the carriers of the Aromatic Infrared Bands (AIBs), but an unambiguous identification of any specific interstellar PAH is still missing. For polar PAHs, pure rotational transitions can be used as spectral fingerprints for identification. Combining dedicated experiments, detailed simulations and observations, we explore d the mm wavelength domain to search for specific rotational transitions of corannulene (C20H10). We performed high-resolution spectroscopic measurements and a simulation of the emission spectrum of ultraviolet-excited C20H10 in the environment of the Red Rectangle (RR), calculating its synthetic rotational spectrum. Based on these results, we conducted a first observational campaign at the IRAM 30-m telescope towards this source to search for several high-J rotational transitions of C20H10. The laboratory detection of the J = 112 ← 111 transition of corannulene showed that no centrifugal splitting is present up to this line. Observations with the IRAM 30-m telescope towards the RR do not show any corannulene emission at any of the observed frequencies, down to a rms noise level of Tmb= 8 mK for the J =135 → 134 transition at 137.615 GHz. Comparing the noise level with the synthetic spectrum, we are able to estimate an upper limit to the fraction of carbon locked in corannulene of about 1.0 × 10−5 relative to the total abundance of carbon in PAHs. The sensitivity achieved in this work shows that radio spectroscopy can be a powerful tool to search for polar PAHs. We compare this upper limit with models for the PAH size distribution, emphasizing that small PAHs are much less abundant than predicted. We show that this cannot be explained by destruction but is more likely related to the chemistry of their formation in the environment of the R
Effect of positive end-expiratory pressure and tidal volume on lung injury induced by alveolar instability
Increased Orbitofrontal Brain Activation after Administration of a Selective Adenosine A2A Antagonist in Cocaine Dependent Subjects
Background: Positron Emission Tomography imaging studies provide evidence of reduced dopamine function in cocaine dependent subjects in the striatum, which is correlated with prefrontal cortical glucose metabolism, particularly in the orbitofrontal cortex. However, whether enhancement of dopamine in the striatum in cocaine dependent subjects would be associated with changes in prefrontal cortical brain activation is unknown. One novel class of medications that enhance dopamine function via heteromer formation with dopamine receptors in the striatum is the selective adenosine A2A receptor antagonists. This study sought to determine the effects administration of the selective adenosine A2A receptor antagonist SYN115 on brain function in cocaine dependent subjects. Methodology/Principle Findings: Twelve cocaine dependent subjects underwent two fMRI scans (one after a dose of placebo and one after a dose of 100 mg of SYN115) while performing a working memory task with three levels of difficulty (3, 5, and 7 digits). fMRI results showed that for 7-digit working memory activation there was significantly greater activation from SYN115 compared to placebo in portions of left (L) lateral orbitofrontal cortex, L insula, and L superior and middle temporal pole. Conclusion/Significance: These findings are consistent with enhanced dopamine function in the striatum in cocaine dependent subjects via blockade of adenosine A2A receptors producing increased brain activation in the orbitofrontal cortex and other cortical regions. This suggests that at least some of the changes in brain activation in prefrontal cortical regions in cocaine dependent subjects may be related to altered striatal dopamine function, and that enhancement of dopamine function via adenosine A2A receptor blockade could be explored further for amelioration of neurobehavioral deficits associated with chronic cocaine use
An assessment of the use of sediment traps for estimating upper ocean particle fluxes
Author Posting. © Sears Foundation for Marine Research, 2007. This article is posted here by permission of Sears Foundation for Marine Research for personal use, not for redistribution. The definitive version was published in Journal of Marine Research 65 (2007): 345–416, doi: 10.1357/002224007781567621This review provides an assessment of sediment trap accuracy issues by gathering data to address trap hydrodynamics, the problem of zooplankton "swimmers," and the solubilization of material after collection. For each topic, the problem is identified, its magnitude and causes reviewed using selected examples, and an update on methods to correct for the potential bias or minimize the problem using new technologies is presented. To minimize hydrodynamic biases due to flow over the trap mouth, the use of neutrally buoyant sediment traps is encouraged. The influence of swimmers is best minimized using traps that limit zooplankton access to the sample collection chamber. New data on the impact of different swimmer removal protocols at the US time-series sites HOT and BATS are compared and shown to be important. Recent data on solubilization are compiled and assessed suggesting selective losses from sinking particles to the trap supernatant after collection, which may alter both fluxes and ratios of elements in long term and typically deeper trap deployments. Different methods are needed to assess shallow and short- term trap solubilization effects, but thus far new incubation experiments suggest these impacts to be small for most elements. A discussion of trap calibration methods reviews independent assessments of flux, including elemental budgets, particle abundance and flux modeling, and emphasizes the utility of U-Th radionuclide calibration methods.WG meetings and production of this report was partially supported by the U.S.
National Science Foundation via grants to the SCOR. Individuals and science efforts discussed herein
were supported by many national science programs, including the U.S. National Science Foundation,
Swedish Research Council, the International Atomic Energy Agency through its support of the Marine
Environmental Laboratory that also receives support from the Government of the Principality of Monaco,
and the Australian Antarctic Science Program. K.B. was supported in part by a WHOI Ocean Life
Institute Fellowship
PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain
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