Peran Dependency, Commitment, Trust Dan Communication Terhadap Kolaborasi Rantai Pasok Dan Kinerja Perusahaan: Studi Pendahuluan

. Supply Chain Collaboration plays a significant role to the effectiveness of organizations. This preliminary study aims to identify social psychology factors that might influence collaborative relationship within a supply chain network, in the context of medium-sized food manufacturing enterprise. The supply chain collaboration practice and its impact of implementation on firm's performance, both operational and financial, were investigated. Based on this purposes, a survey within a case study approach was conducted. The data were collected from one medium scale food manufacturing enterprise. A partial least squares-path modeling (PLS-PM) was proposed for conceptualizing and measuring the effects of dependence, commitment, trust, and communication on supply chain collaboration. The effect of supply chain collaboration on firm's performance was also measured and quantified. From buyer's perspective, the study reveals that commitment and trust positively affect supply chain collaboration and that supply chain collaboration has a considerable effect on firm's performance. Meanwhile, dependence influences the collaboration indirectly through commitment, while communication influences the collaboration indirectly through trust

Magnetic field dynamos and magnetically triggered flow instabilities

The project A2 of the LIMTECH Alliance aimed at a better understanding of those magnetohydrodynamic instabilities that are relevant for the generation and the action of cosmic magnetic fields. These comprise the hydromagnetic dynamo effect and various magnetically triggered flow instabilities, such as the magnetorotational instability and the Tayler instability. The project was intended to support the experimental capabilities to become available in the framework of the DREsden Sodium facility for DYNamo and thermohydraulic studies (DRESDYN). An associated starting grant was focused on the dimensioning of a liquid metal experiment on the newly found magnetic destabilization of rotating flows with positive shear. In this paper, the main results of these two projects are summarized

Induction in a von Karman flow driven by ferromagnetic impellers

We study magnetohydrodynamics in a von K\'arm\'an flow driven by the rotation of impellers made of material with varying electrical conductivity and magnetic permeability. Gallium is the working fluid and magnetic Reynolds numbers of order unity are achieved. We find that specific induction effects arise when the impeller's electric and magnetic characteristics differ from that of the fluid. Implications in regards to the VKS dynamo are discussed.Comment: 14 pages, 7 figure

Linear magnetic resonance imaging measurements of the hippocampal formation differ in young versus old dogs

Age-related hippocampal formation (HF) atrophy has been documented on MRI studies using volumetric analysis and visual rating scales.This retrospective cross-sectional study aimed to compare linear MRI measurements of the HF between young (1–3 years) and old (>10 years) non-brachycephalic dogs, with normal brain anatomy and cerebrospinal fluid (CSF) analysis. Right and left hippocampal formation height (HFH), height of the brain (HB) and mean HFH/HB ratio were measured by two observers on a transverse T2 fluid-attenuated inversion recovery sequence containing rostral colliculi and mesencephalic aqueduct.119 MRI studies were enrolled: 75 young and 44 old dogs. Left and right HFH were greater (p<0.0001) in young, while HB was greater in old dogs (p=0.024). Mean HFH/HB ratio was 15.66 per cent and 18.30 per cent in old and young dogs (p<0.0001). No differences were found comparing measurements between epileptic and non-epileptic dogs.Old dogs have a greater HB; this may represent the different study populations or a statistical phenomenon. Ageing affects HF linear measurements. A reduction of mean HFH/HB ratio between 18.30 per cent and 15.66 per cent should be considered a physiological age-related process of the canine lifespan. The use of mean HFH/HB ratio could be considered for quantifying brain atrophy in elderly dogs

On the viability of the shearing box approximation for numerical studies of MHD turbulence in accretion disks

Most of our knowledge on the nonlinear development of the magneto-rotational instability (MRI) relies on the results of numerical simulations employing the shearing box (SB) approximation. A number of difficulties arising from this approach have recently been pointed out in the literature. We thoroughly examine the effects of the assumptions made and numerical techniques employed in SB simulations. This is done in order to clarify and gain better understanding of those difficulties as well as of a number of additional serious problems, raised here for the first time, and of their impact on the results. Analytical derivations and estimates as well as comparative analysis to methods used in the numerical study of turbulence are used. Numerical experiments are performed to support some of our claims and conjectures. The following problems, arising from the (virtually exclusive) use of the SB simulations as a tool for the understanding and quantification of the nonlinear MRI development in disks, are analyzed and discussed: (i) inconsistencies in the application of the SB approximation itself; (ii) the limited spatial scale of the SB; (iii) the lack of convergence of most ideal MHD simulations; (iv) side-effects of the SB symmetry and the non-trivial nature of the linear MRI; (v) physical artifacts arising on the too small box scale due to periodic boundary conditions. The computational and theoretical challenge posed by the MHD turbulence problem in accretion disks cannot be met by the SB approximation, as it has been used to date. A new strategy to confront this challenge is proposed, based on techniques widely used in numerical studies of turbulent flows - developing (e.g., with the help of local numerical studies) a sub-grid turbulence model and implementing it in global calculations.Comment: Accepted for publication in Astronomy and Astrophysic

Aspects of high strain rate industrial forging of Inconel 718

The major part of all material and microstructural data used for the modelling of nickel superalloy forgings is obtained from uniaxial laboratory tests with limited plastic strain and very simple thermo-mechanical history. At the same time, new challenges in near net shape industrial forging require a high level of reliability of modelling prediction of metal flow, for predicting the risk of defects and microstructural transformation. A few recently conducted benchmarking studies have shown that despite the availability of various material models (including microstructural ones) embedded in commercial FE software, in many cases, the level of prediction remains unsatisfactory. This is especially true for fast industrial forging processes (like screw press or hammer forgings). This paper suggests a methodology for processing the results from industrial forgings for obtaining robust data for calibration, validation, and improvement of material and microstructural models. This also can provide additional information on the material science behind the microstructural phenomena, which are problematic to capture and study using simple uniaxial tests

B Lymphocytes as Targets of the Immunomodulatory Properties of Human Amniotic Mesenchymal Stromal Cells

Mesenchymal stromal cells (MSC) from the amniotic membrane of human term placenta (hAMSC), and the conditioned medium generated from their culture (CM-hAMSC) offer significant tools for their use in regenerative medicine mainly due to their immunomodulatory properties. Interestingly, hAMSC and their CM have been successfully exploited in preclinical disease models of inflammatory and autoimmune diseases where depletion or modulation of B cells have been indicated as an effective treatment, such as inflammatory bowel disease, lung fibrosis, would healing, collagen-induced arthritis, and multiple sclerosis. While the interactions between hAMSC or CM-hAMSC and T lymphocytes, monocytes, dendritic cells, and macrophages has been extensively explored, how they affect B lymphocytes remains unclear. Considering that B cells are key players in the adaptive immune response and are a central component of different diseases, in this study we investigated the in vitro properties of hAMSC and CM-hAMSC on B cells. We provide evidence that both hAMSC and CM-hAMSC strongly suppressed CpG-activated B-cell proliferation. Moreover, CM-hAMSC blocked B-cell differentiation, with an increase of the proportion of mature B cells, and a reduction of antibody secreting cell formation. We observed the strong inhibition of B cell terminal differentiation into CD138+ plasma cells, as further shown by a significant decrease of the expression of interferon regulatory factor 4 (IRF-4), PR/SET domain 1(PRDM1), and X-box binding protein 1 (XBP-1) genes. Our results point out that the mechanism by which CM-hAMSC impacts B cell proliferation and differentiation is mediated by secreted factors, and prostanoids are partially involved in these actions. Factors contained in the CM-hAMSC decreased the CpG-uptake sensors (CD205, CD14, and TLR9), suggesting that B cell stimulation was affected early on. CM-hAMSC also decreased the expression of interleukin-1 receptor-associated kinase (IRAK)-4, consequently inhibiting the entire CpG-induced downstream signaling pathway. Overall, these findings add insight into the mechanism of action of hAMSC and CM-hAMSC and are useful to better design their potential therapeutic application in B-cell mediated diseases

DNA barcoding reveals the coral “laboratory-rat”, Stylophora pistillata encompasses multiple identities

Stylophora pistillata is a widely used coral “lab-rat” species with highly variable morphology and a broad biogeographic range (Red Sea to western central Pacific). Here we show, by analysing Cytochorme Oxidase I sequences, from 241 samples across this range, that this taxon in fact comprises four deeply divergent clades corresponding to the Pacific-Western Australia, Chagos-Madagascar-South Africa, Gulf of Aden-Zanzibar-Madagascar, and Red Sea-Persian/Arabian Gulf-Kenya. On the basis of the fossil record of Stylophora, these four clades diverged from one another 51.5-29.6 Mya, i.e., long before the closure of the Tethyan connection between the tropical Indo-West Pacific and Atlantic in the early Miocene (16–24 Mya) and should be recognised as four distinct species. These findings have implications for comparative ecological and/or physiological studies carried out using Stylophora pistillata as a model species, and highlight the fact that phenotypic plasticity, thought to be common in scleractinian corals, can mask significant genetic variation